EPS-AIM-00028

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-AIM-00028

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	200.5	4.1E-59	659	902	244

Status

Unreviewed

Ensembl Protein

ENSAMEP00000006676

UniProt Accession

G1LIB8;

Protein Name

Protein Synonyms/Alias

Gene Name

PHLPP1

Gene Synonyms/Alias

PHLPP1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSAMEG00000006315	ENSAMEP00000006636	ENSAMET00000006916
ENSAMEG00000006315	ENSAMEP00000006676	ENSAMET00000006957
ENSAMEG00000006315	ENSAMEP00000006669	ENSAMET00000006950

Organism

Ailuropoda melanoleuca

Functional Description

Protein Length

1183

Protein Sequence
(FASTA)

LKCLLVFVSG KPHSTGSSER IQLSGTYNVR KGKMQLPVNR WTRRQVILCG TCLIVSSVKD 60

SLTGKMHVLP LIGGKVEEVK KHQHCLAFTS SGPQSQTYYI CFDTFTEYLR WLRQVSKIAS 120

QRISSVDLSC CSLEHLPANL FYSQDLTHLN LKQNFLRQNP CLLAARGLNE LQRFTKLKSL 180

NLSNNHLGDF PLAVCNIPTL TELNVSCNAL RAVPAAVGVM HNLQTFLLDG NFLQALPPEL 240

ENMHQLSYLG LSFNEFADIP EVLEKLTAVD KLCMSGNCME TLRLQALRKM PHIKHVDLRL 300

NVIRKLIADE VDFLQHVTQL DLRDNKLGDL DTMIFNNIEV LHCERNQLVT LNICGYFLKA 360

LYAASNELVQ LDVFPVPNYL SYMDVSRNCL ENVPEWVCES RKLEVLDVGH NQICELPARL 420

FCNSSLRKLL AGHNQLTRLP ERLERTSVEV LDVQHNQLLE LPPSLLMKAN SLRFLNASAN 480

KLETLPPATL SEETNSILQE LYLTNNNLTD KCVPLLTGHP HLKILHMAYN RLQSFPASKM 540

AKLEELEEID ISGNKLKAIP TTIMNCRRMH TMIAHSNCIE VFPEVMQLPE IKCVDLSCNE 600

LSEVTLPENL PPKLQELDLT GNPRLVLDHK TLELLNNIRC FKIDQPSAGD ASGAPAVWSH 660

GYTEASGVKN KLCVAALSVN NFCDNREALY GVFDGDRNVE VPYLLQCTMS DILAEELQKT 720

KNEEEYMVNT FIVMQRKLGT AGQKLGGAAV LCHIKHDPMD PGGSFTLTSA NVGKCQTVLC 780

RNGKPLPLSR SYVMSCEEEW KRIKQHKAII TEDGKVNGVT ESTRILGYTF LHPSVVPRPH 840

VQSVPLTPQD EFFILGSKGL WDSLSGEEAV AAVRPVPDAL AAAKKLCTLA QSYGCRDLSA 900

VVVQLSVTED SFCCCELGAG GAGPPPSPGI FPPSVSMVIK ERPADALGVP SSSSGLASEM 960

SSELSTSEMS SEVGSTASDE PPPGALAESS PAYASEPRCM LHPVGLASSF QRQLSSATFS 1020

SAFSDNGLDS DDEEPIEGVF SNGSRVEVEV DIHCSRAKEK EQQRPLHAPA EASDEGIVIS 1080

ANEDEPGLPR RADAAATGTI GRRRANGSVA PQERSHNVIE VAADAPLRKP GGYFAAPAQP 1140

DPEDQFIIPP ELEEEVKEMM KKQQPPARPC PGDPLPDYCD TPL 1183

Nucleotide Sequence
(FASTA)

CTAAAATGTT TGCTTGTGTT TGTTTCAGGA AAACCTCACA GCACCGGTAG CTCTGAACGG 60

ATTCAGCTCT CAGGAACGTA TAATGTCCGT AAAGGCAAAA TGCAGTTGCC AGTAAACCGA 120

TGGACCAGAC GCCAAGTCAT CCTGTGTGGG ACCTGCCTAA TAGTATCATC TGTGAAAGAC 180

AGCTTGACTG GAAAGATGCA TGTTCTGCCA CTAATTGGTG GAAAAGTAGA AGAAGTGAAA 240

AAGCACCAGC ACTGTTTAGC ATTTACCTCC TCTGGACCCC AAAGCCAGAC TTACTACATT 300

TGTTTTGATA CATTCACAGA GTATTTAAGG TGGCTTCGAC AAGTCTCCAA GATTGCATCA 360

CAGCGCATCA GCTCAGTGGA CCTCTCGTGT TGTAGCCTGG AGCATCTGCC TGCCAACCTC 420

TTCTACAGCC AGGACCTCAC TCATCTCAAC TTAAAACAAA ACTTCCTAAG GCAGAATCCC 480

TGCCTACTAG CTGCCAGGGG GCTCAATGAA CTGCAAAGGT TCACCAAGTT GAAGAGTCTT 540

AACCTTTCCA ATAATCATTT AGGGGACTTC CCATTAGCAG TCTGCAATAT ACCAACCCTG 600

ACCGAGCTGA ACGTGTCCTG CAACGCCCTG CGAGCAGTCC CAGCAGCCGT CGGAGTTATG 660

CACAACTTAC AGACATTCTT GTTGGATGGG AACTTCCTCC AGGCCCTTCC TCCTGAGTTG 720

GAGAATATGC ATCAGCTTAG TTATCTTGGT CTTTCTTTCA ATGAATTCGC TGACATTCCA 780

GAGGTTTTGG AGAAATTGAC TGCTGTGGAT AAACTTTGTA TGTCTGGAAA CTGTATGGAG 840

ACCCTTAGGC TACAGGCTTT AAGAAAAATG CCTCACATTA AACATGTGGA TCTAAGACTG 900

AATGTAATTA GGAAGCTAAT AGCAGATGAA GTGGACTTTC TCCAGCATGT CACTCAGCTT 960

GATCTGCGCG ACAATAAGCT TGGTGATCTA GATACCATGA TTTTCAACAA CATTGAAGTT 1020

TTACACTGTG AAAGGAATCA GCTGGTGACA TTAAACATCT GTGGCTATTT CCTAAAAGCA 1080

CTCTATGCCG CTTCTAATGA ACTTGTTCAA CTGGATGTTT TCCCAGTTCC AAATTATCTG 1140

TCCTACATGG ATGTTTCAAG GAACTGCTTA GAAAACGTGC CTGAGTGGGT ATGCGAAAGC 1200

CGAAAGCTAG AAGTTTTGGA TGTTGGCCAT AATCAAATAT GTGAACTTCC TGCGCGCTTA 1260

TTTTGTAATA GTAGTCTCCG GAAGCTGCTG GCAGGACACA ACCAGCTGAC GAGGCTCCCT 1320

GAGAGGCTGG AGAGGACCTC AGTGGAGGTC TTGGATGTGC AGCACAACCA GCTCCTGGAG 1380

CTGCCGCCAA GCCTGCTGAT GAAGGCCAAC AGCCTGAGAT TCCTGAATGC ATCTGCAAAC 1440

AAACTGGAAA CCCTTCCTCC AGCCACTCTT TCTGAAGAGA CGAACAGCAT CTTACAGGAG 1500

TTGTATTTGA CAAATAACAA CCTCACAGAT AAATGTGTGC CCTTGTTAAC AGGACATCCC 1560

CATCTAAAGA TCCTTCACAT GGCCTACAAC CGACTTCAGA GTTTTCCAGC AAGTAAAATG 1620

GCCAAACTGG AGGAACTTGA AGAAATTGAC ATCAGTGGGA ATAAACTGAA GGCCATCCCG 1680

ACGACCATCA TGAATTGCCG GCGCATGCAC ACCATGATTG CTCATTCTAA TTGCATCGAA 1740

GTCTTTCCTG AGGTCATGCA GCTCCCAGAA ATCAAGTGCG TGGACCTGAG CTGTAATGAG 1800

CTAAGCGAAG TCACTTTACC AGAAAACCTG CCTCCAAAGC TACAAGAACT AGATCTGACT 1860

GGAAACCCCC GACTCGTCCT CGATCACAAA ACCTTGGAAC TGCTGAATAA TATCCGCTGT 1920

TTCAAGATTG ATCAACCTTC AGCAGGCGAT GCGTCCGGAG CCCCAGCCGT GTGGAGCCAT 1980

GGCTACACCG AAGCCTCGGG GGTAAAAAAC AAGTTGTGTG TTGCGGCCCT GTCAGTGAAC 2040

AACTTCTGCG ACAACCGGGA GGCCCTGTAC GGGGTATTTG ACGGAGACCG TAACGTGGAG 2100

GTGCCCTACC TTCTCCAGTG CACTATGAGT GACATTTTGG CTGAAGAGTT GCAGAAAACA 2160

AAAAATGAGG AAGAATACAT GGTTAATACA TTCATTGTTA TGCAAAGGAA ACTTGGAACT 2220

GCTGGGCAGA AACTTGGAGG TGCTGCTGTC CTCTGTCATA TCAAGCATGA CCCCATGGAC 2280

CCAGGGGGAT CCTTCACCTT GACCTCTGCT AATGTAGGCA AGTGCCAGAC GGTTCTCTGT 2340

CGGAACGGGA AGCCGTTGCC TCTGTCCAGG TCATACGTCA TGAGCTGTGA AGAAGAATGG 2400

AAGAGAATTA AACAGCACAA GGCCATTATC ACAGAGGACG GCAAGGTGAA CGGCGTGACG 2460

GAGTCCACGC GCATTCTGGG CTACACTTTC CTCCACCCCA GCGTGGTGCC GCGCCCCCAC 2520

GTGCAGTCCG TGCCCCTGAC GCCCCAGGAC GAGTTCTTCA TCCTGGGCAG CAAGGGCCTG 2580

TGGGACAGCC TGTCCGGCGA GGAGGCGGTG GCCGCCGTGC GCCCAGTGCC CGACGCCCTG 2640

GCCGCCGCCA AGAAGCTGTG CACGCTGGCG CAGAGCTACG GCTGCCGCGA CCTGAGCGCC 2700

GTGGTGGTTC AGCTCAGCGT CACGGAGGAC AGCTTCTGCT GCTGCGAGCT GGGAGCGGGG 2760

GGCGCCGGGC CGCCGCCCAG CCCGGGCATC TTCCCGCCGT CCGTCAGCAT GGTGATCAAG 2820

GAGCGGCCGG CCGACGCCCT GGGCGTGCCG TCCTCCAGCA GTGGCCTGGC GTCCGAGATG 2880

AGCAGCGAGC TGTCCACGTC TGAGATGAGC AGCGAGGTGG GCTCCACCGC CTCGGACGAG 2940

CCCCCGCCGG GCGCGCTGGC GGAGAGCAGC CCCGCGTATG CCAGCGAGCC GCGCTGCATG 3000

CTGCACCCAG TGGGCCTGGC CAGCTCATTC CAGCGCCAGC TGTCCAGCGC CACCTTTTCC 3060

AGCGCCTTCT CCGACAACGG CCTGGACAGC GACGACGAGG AGCCCATCGA GGGCGTCTTC 3120

AGCAACGGCA GCCGCGTGGA GGTGGAGGTG GACATCCACT GCAGCCGGGC CAAGGAGAAG 3180

GAGCAGCAGC GCCCGCTGCA CGCGCCGGCC GAGGCCAGCG ACGAGGGCAT CGTCATCAGC 3240

GCCAACGAGG ACGAGCCGGG GCTGCCCCGG CGGGCGGACG CGGCGGCCAC GGGGACCATC 3300

GGGCGGCGCA GGGCCAACGG CTCCGTCGCG CCCCAGGAAA GGAGCCACAA CGTGATCGAG 3360

GTGGCGGCGG ACGCGCCTCT CCGAAAACCC GGGGGCTACT TCGCGGCGCC GGCCCAGCCG 3420

GACCCCGAGG ATCAGTTCAT CATCCCGCCG GAGCTGGAGG AGGAGGTCAA GGAAATGATG 3480

AAGAAGCAGC AGCCGCCGGC GCGGCCGTGC CCGGGGGACC CGCTGCCAGA CTACTGTGAC 3540

ACGCCACTAT GA 3552

Domain Profile

S: 2     lvgvvsvngrrnemedavtsspnflkspekkdrlaffgvyDGhggsevakfcseklheil  61

         ++g+++ +g +n+++ a+ s++nf++++e+     ++gv+DG+++ ev + +++++++il

Q: 659   SHGYTEASGVKNKLCVAALSVNNFCDNREA-----LYGVFDGDRNVEVPYLLQCTMSDIL  713

         689***********************9885.....9************************

S: 62    aeelesseseerkvkkalakaFlstdeelkvleeksldidksGstavvalikds......  115

         aeel+    ++++ ++++ ++F+ ++++l       ++ +k G +av+++ik++

Q: 714   AEELQ----KTKNEEEYMVNTFIVMQRKL------GTAGQKLGGAAVLCHIKHDpmdpgg  763

         ***99....999*****************......99****************999****

S: 116   ..klyvanvGdSravLcrngkavelssdHkpsredEleRieeaggsvilkdgaRvlGvLa  173

           +l+ anvG++++vLcrngk+++ls+ + +s+e+E +Ri+++++ ++++   +v+Gv++

Q: 764   sfTLTSANVGKCQTVLCRNGKPLPLSRSYVMSCEEEWKRIKQHKAIITEDG--KVNGVTE  821

         *99*****************************************9999998..*******

S: 174   vsRalGdlylkpyvtpePevtshrltsedefliLasDGlwdvvsneeavslvrdvlekke  233

          +R lG ++l+p v+p+P+v+s++lt++def+iL+s+Glwd +s eeav++vr v +

Q: 822   STRILGYTFLHPSVVPRPHVQSVPLTPQDEFFILGSKGLWDSLSGEEAVAAVRPVPD---  878

         *********************************************************...

S: 234   aeqeaakkLvklalargskdnvsaiv  259

          + +aakkL++la+++g++d   a+v

Q: 879   -ALAAAKKLCTLAQSYGCRDLS-AVV  902

         .*****************9976.444

Domain Sequence
(FASTA)

SHGYTEASGV KNKLCVAALS VNNFCDNREA LYGVFDGDRN VEVPYLLQCT MSDILAEELQ 60

KTKNEEEYMV NTFIVMQRKL GTAGQKLGGA AVLCHIKHDP MDPGGSFTLT SANVGKCQTV 120

LCRNGKPLPL SRSYVMSCEE EWKRIKQHKA IITEDGKVNG VTESTRILGY TFLHPSVVPR 180

PHVQSVPLTP QDEFFILGSK GLWDSLSGEE AVAAVRPVPD ALAAAKKLCT LAQSYGCRDL 240

SAVV 244

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Loxodonta africana"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>