EKS-AIM-00398

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-AIM-00398

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/WEE	327.1	7.4E-98	108	356	249

Status

Unreviewed

Ensembl Protein

ENSAMEP00000008844

UniProt Accession

G1LP64;

Protein Name

Protein Synonyms/Alias

Gene Name

PKMYT1

Gene Synonyms/Alias

PKMYT1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSAMEG00000008397	ENSAMEP00000008844	ENSAMET00000009221

Organism

Ailuropoda melanoleuca

Functional Description

Protein Length

500

Protein Sequence
(FASTA)

CTSGAPVLAM PVPTEGTPPS LSGIPVPAYF RHAEPGFSLK RPGGLSRSLP PRPPAKGSIP 60

ISRLFPPRTP GWHQPQPRRV SFRGKAPETL QSPSYDPSRP ESFFQQSFQR LGRLGHGSYG 120

EVFKVRSKED GRLYAIKRSM SPFRGPKDRA RKLAEVGGHE KVGQHPRCVR LEQAWEEGGI 180

LYLQTELCGP SLQQHCEAWG TGLPEAQVWG YLRDTLLALA HLHGQGLVHL DVKPANIFLG 240

PRGRCKLGDF GLLVELGTSG AGEAQEGDPR YMAPELLQGS YGTAADVFSL GLTILEVACN 300

MELPHGGEGW QQLRQGYLPP EFTAGLSSEL RSVLTMMLEP DPKLRATASA LLALPMLRQP 360

RPWSVLWYMA ADVLSRGWAL WQALLSLLCW FWHGLAHPVS WLQPPSPPAT PPGSPPCSLL 420

LDSSLSSNWD DDSTGLSLSP EAVLARAAGN TSTPRNGSPA PRNRDALDLS DIDSEPPRGS 480

FPSFEPRNLL SLFEDSLGPT 500

Nucleotide Sequence
(FASTA)

TGCACCTCAG GGGCTCCTGT GCTGGCCATG CCTGTGCCCA CGGAGGGCAC CCCTCCATCT 60

CTGAGTGGTA TCCCAGTCCC AGCCTACTTC CGCCATGCAG AACCTGGCTT CTCCCTCAAG 120

AGGCCTGGGG GGCTCAGTCG GAGCCTCCCA CCCCGGCCCC CTGCCAAGGG CAGCATCCCC 180

ATCAGCCGCC TCTTCCCTCC TCGGACCCCG GGCTGGCACC AGCCCCAGCC CCGGAGGGTG 240

TCATTCCGAG GCAAAGCCCC TGAGACCCTG CAGAGCCCCT CATATGACCC CAGCCGGCCG 300

GAGTCCTTTT TCCAGCAGAG TTTCCAGAGG CTTGGCCGCC TGGGCCACGG CTCCTATGGA 360

GAGGTCTTCA AGGTACGCTC TAAGGAAGAC GGCCGACTCT ATGCCATAAA GCGCTCTATG 420

TCACCATTCC GGGGCCCCAA GGACCGGGCC CGCAAGCTGG CCGAGGTCGG CGGCCACGAG 480

AAGGTGGGGC AGCACCCGCG CTGTGTGCGG CTGGAGCAAG CCTGGGAGGA GGGCGGCATC 540

CTGTACCTGC AGACAGAGCT GTGTGGGCCC AGCCTACAGC AGCACTGTGA GGCCTGGGGC 600

ACCGGCCTAC CTGAGGCCCA GGTCTGGGGC TACCTGCGGG ATACCCTGCT TGCTCTGGCT 660

CACCTCCACG GCCAAGGCCT GGTCCACCTT GATGTCAAGC CTGCCAACAT CTTCCTGGGG 720

CCCCGGGGCC GTTGCAAGCT GGGTGACTTT GGGCTGCTGG TTGAGCTGGG TACATCCGGA 780

GCTGGTGAGG CGCAGGAAGG AGACCCCCGG TACATGGCCC CTGAGCTGCT GCAGGGCTCC 840

TATGGGACAG CGGCGGACGT GTTCAGTCTG GGTCTCACCA TCCTGGAAGT GGCATGCAAC 900

ATGGAGCTAC CCCATGGTGG AGAGGGCTGG CAGCAGCTTC GCCAGGGCTA TCTGCCCCCT 960

GAGTTTACTG CTGGCCTGTC TTCTGAGCTG CGTTCTGTTC TCACCATGAT GCTGGAACCT 1020

GACCCCAAGC TGCGGGCCAC AGCCTCGGCC CTGCTGGCGC TGCCCATGCT CAGGCAGCCT 1080

CGGCCCTGGA GCGTTCTGTG GTATATGGCT GCCGATGTCC TCAGTCGAGG GTGGGCCCTG 1140

TGGCAGGCCC TGCTTTCCTT GCTGTGCTGG TTCTGGCACG GACTAGCTCA CCCTGTGAGC 1200

TGGCTGCAGC CCCCGAGCCC ACCAGCCACC CCACCTGGCT CCCCACCCTG CAGCCTCCTC 1260

CTGGACAGCA GCCTCTCCAG CAACTGGGAT GATGACAGCA CAGGGCTCTC ACTCTCTCCG 1320

GAGGCCGTCC TGGCCAGGGC TGCCGGGAAC ACCTCCACCC CCCGCAATGG CTCCCCTGCC 1380

CCCCGGAACA GGGATGCCCT GGACCTCAGT GACATTGACT CTGAGCCCCC TCGGGGTTCC 1440

TTCCCCTCCT TTGAACCTCG GAACCTCCTC AGCCTGTTTG AGGACTCACT GGGCCCAACC 1500

TGA 1503

Domain Profile

S: 1     FeevekiGkGefgevfkvvkredgklyAikkskkplkglskekkalrEvtahavlgqhen  60

         F+++ ++G+G++gevfkv+++edg+lyAik+s++p++g ++++++l+Ev +h+++gqh+

Q: 108   FQRLGRLGHGSYGEVFKVRSKEDGRLYAIKRSMSPFRGPKDRARKLAEVGGHEKVGQHPR  167

         89999*******************************************************

S: 61    vvryisaWeeddslyiqtElCeggsLeaalqeceakkkaleeaelkkilldlllglrylH  120

         +vr+ +aWee ++ly+qtElC g sL+++   cea+ + l+ea+++ +l d ll+l +lH

Q: 168   CVRLEQAWEEGGILYLQTELC-GPSLQQH---CEAWGTGLPEAQVWGYLRDTLLALAHLH  223

         *********************.*******...****************************

S: 121   ssslvHlDikpenifitkevtlklgDlGlvtelnsedkskveEGDsrylakEilqeeysk  180

          + lvHlD+kp+nif+  ++++klgD+Gl++el+++ + +++EGD ry+a+E+lq++y +

Q: 224   GQGLVHLDVKPANIFLGPRGRCKLGDFGLLVELGTSGAGEAQEGDPRYMAPELLQGSYGT  283

         ************************************************************

S: 181   lkaDiFslgltilevaanvelPsnGeaWhklRkgklpdeilkelsedlrellklmlepdp  240

         + aD+Fslgltileva+n+elP+ Ge W++lR+g+lp+e+++ ls++lr++l +mlepdp

Q: 284   A-ADVFSLGLTILEVACNMELPHGGEGWQQLRQGYLPPEFTAGLSSELRSVLTMMLEPDP  342

         *.**********************************************************

S: 241   erRptaeellkhev  254

         + R+ta++ll+ ++

Q: 343   KLRATASALLALPM  356

         **********9876

Domain Sequence
(FASTA)

FQRLGRLGHG SYGEVFKVRS KEDGRLYAIK RSMSPFRGPK DRARKLAEVG GHEKVGQHPR 60

CVRLEQAWEE GGILYLQTEL CGPSLQQHCE AWGTGLPEAQ VWGYLRDTLL ALAHLHGQGL 120

VHLDVKPANI FLGPRGRCKL GDFGLLVELG TSGAGEAQEG DPRYMAPELL QGSYGTAADV 180

FSLGLTILEV ACNMELPHGG EGWQQLRQGY LPPEFTAGLS SELRSVLTMM LEPDPKLRAT 240

ASALLALPM 249

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gasterosteus aculeatus"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005737	; C:cytoplasm
GO:0005634	; C:nucleus
GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0010923	; P:negative regulation of phosphatase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013