EKS-AIM-00084

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-AIM-00084

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Atypical/PIKK	444.2	3.2E-133	2152	2476	325

Status

Unreviewed

Ensembl Protein

ENSAMEP00000010132

UniProt Accession

G1LST9;

Protein Name

Protein Synonyms/Alias

Gene Name

MTOR

Gene Synonyms/Alias

MTOR;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSAMEG00000009623	ENSAMEP00000010132	ENSAMET00000010573

Organism

Ailuropoda melanoleuca

Functional Description

Protein Length

2544

Protein Sequence
(FASTA)

MLGTGPTAAT AATTTSSNVS VLQQFASGLK SRNEETRAKA AKELQHYVTM ELREMSQEES 60

TRFYDQLNHH IFELVSSSDA NERKGGILAI ASLIGVEGGN ATRIGRFANY LRNLLPSNDP 120

VVMEMASKAI GRLAMAGDTF TAEYVEFEVK RALEWLGADR NEGRRHAAVL VLRELAISVP 180

TFFFQQVQPF FDNIFVAVWD PKQAIREGAV AALRACLILT TQREPKEMQK PQWYRHTFEE 240

AEKGFDETLA KEKGMNRDDR IHGALLILNE LVRISSMEGE RLREEMEEIT QQQLVHDKYC 300

KDLMGFGTKP RHITPFTSFQ AVQPPQSNAL VGLLGYSSHQ GLMGFGASPS PAKSTLVESR 360

CCRDLMEEKF DQVCQWVLKC RNSKNSLIQM TILNLLPRLA AFRPSAFTDT QYLQDTMNHV 420

LSCVKKEKER TAAFQALGLL SVAVRSEFKV YLPRVLDIIR AALPPKDFAH KRQKAMQVDA 480

TVFTCISMLA RAMGPGIQQD IKELLEPMLA VGLSPALTAV LYDLSRQIPQ LKKDIQDGLL 540

KMLSLVLMHK PLRHPGMPKG LAHQLASPGL TALPEASDVG SITLALRTLG SFEFEGHSLT 600

QFVRHCADHF LNSEHKEIRM EAARTCSRLL TPSVHLISGH AHVVSQTAVQ VVADVLSKLL 660

VVGITDPDPD IRYCVLASLD ERFDAHLAQA ENLQALFVAL NDQVFEIREL AICTVGRLSS 720

MNPAFVMPFL RKMLIQILTE LEHSGIGRIK EQSARMLGHL VSNAPRLIRP YMEPILKALI 780

LKLKDPDPDP NPGVINNVLA TIGELAQVSG LEMRKWVDEL FIIIMDMLQD SSLLAKRQVA 840

LWTLGQLVAS TGYVVEPYRK YPTLLEVLLN FLKTEQNQGT RREAIRVLGL LGALDPYKHK 900

VNIGMIDQSR DASAVSLSES KSSQDSSDYS TSEMLVNMGN LPLDEFYPAV SMVALMRIFR 960

DQSLSHHHTM VVQAITFIFK SLGLKCVQFL PQVMPTFLNV IRVCDGAIRE FLFQQLGMLV 1020

SFVKSHIRPY MDEIVTLMRE FWVMNTSIQS TIILLIEQIV VALGGEFKLY LPQLIPHMLR 1080

VFMHDNSPGR IVSIKLLAAI QLFGANLDDY LHLLLPPIVK LFDAPEVPLP SRKAALETVD 1140

RLTESLDFTD YASRIIHPIV RTLDQSPELR PTAMDTLSSL VFQLGKKYQI FIPMVNKVLV 1200

RHRINHQRYD VLICRIVKGY TLADEEEDPL IYQHRMLRSG QGDALASGPV ETGPMKKLHV 1260

STINLQKAWG AARRVSKDDW LEWLRRLSLE LLKDSSSPSL RSCWALAQAY NPMARDLFNA 1320

AFVSCWSELN EDQQDELIRS IELALTSQDI AEVTQTLLNL AEFMEHSDKG PLPLRDDNGI 1380

VLLGERAAKC RAYAKALHYK ELEFQKGPTP AILESLISIN NKLQQPEAAA GVLEYAMKHF 1440

GELEIQATWY EKLHEWEDAL VAYDKKMDTN KDDPELMLGR MRCLEALGEW GQLHQQCCEK 1500

WTLVNDETQA KMARMAAAAA WGLGQWDSME EYTCMIPRDT HDGAFYRAVL ALHQDLFSLA 1560

QQCIDKARDL LDAELTAMAG ESYSRAYGAM VSCHMLSELE EVIQYKLVPE RREIIRQIWW 1620

ERLQGCQRIV EDWQKILMVR SLVVSPHEDM RTWLKYASLC GKSGRLALAH KTLVLLLGVD 1680

PSRQLDHPLP TVHPQVTYAY MKNMWKSARK IDAFQHMQHF VQTVQQQAQH AIATEDQQHK 1740

QELHKLMARC FLKLGEWQLN LQGINESTIP KVLQYYSAAT EHDRSWYKAW HAWAVMNFEA 1800

VLHYKHQNQA RDEKKKLRHA SGANITSTST AATTAATATA TSTEGSNSES EAESTENSPT 1860

PSPLQKKVTE DLSKTLLMYT VPAVQGFFRS ISLSRGNNLQ DTLRVLTLWF DYGHWPDVNE 1920

ALVEGVKAIQ IDTWLQVIPQ LIARIDTPRP LVGRLIHQLL TDIGRYHPQA LIYPLTVASK 1980

STTTARHNAA NKILKNMCEH SNTLVQQAMM VSEELIRVAI LWHEMWHEGL EEASRLYFGE 2040

RNVKGMFEVL EPLHAMMERG PQTLKETSFN QAYGRDLMEA QEWCRKYMKS GNVKDLTQAW 2100

DLYYHVFRRI SKQLPQLTSL ELQYVSPKLL MCRDLELAVP GTYDPNQPII RIQSIAPSLQ 2160

VITSKQRPRK LTLMGSNGHE FVFLLKGHED LRQDERVMQL FGLVNTLLAN DPTSLRKNLS 2220

IQRYAVIPLS TNSGLIGWVP HCDTLHALIR DYREKKKILL NIEHRIMLRM APDYDHLTLM 2280

QKVEVFEHAV NNTAGDDLAK LLWLKSPSSE VWFDRRTNYT RSLAVMSMVG YILGLGDRHP 2340

SNLMLDRLSG KILHIDFGDC FEVAMTREKF PEKIPFRLTR MLTNAMEVTG LDGNYRITCH 2400

TVMEVLREHK DSVMAVLEAF VYDPLLNWRL MDTNTKGNKR SRTRTDSYSA GQSVEILDGV 2460

ELGEPAHKKT GTTVPESIHS FIGDGLVKPE ALNKKAIQII NRVRDKLTGR DFSHDETLDV 2520

PTQVELLIKQ ATSHENLCQC YIGW 2544

Nucleotide Sequence
(FASTA)

ATGCTGGGAA CTGGACCCAC TGCCGCCACC GCAGCTACCA CCACGTCCAG CAACGTGAGC 60

GTCCTGCAGC AGTTCGCCAG TGGCCTGAAG AGCCGGAATG AGGAGACCAG GGCCAAAGCT 120

GCCAAGGAGC TCCAGCACTA TGTCACCATG GAGCTTCGAG AGATGAGTCA AGAGGAGTCT 180

ACTCGATTCT ATGATCAGCT GAACCATCAC ATTTTTGAAC TGGTTTCCAG CTCAGATGCC 240

AATGAGAGGA AAGGTGGCAT CTTGGCCATA GCCAGCCTTA TAGGAGTGGA AGGCGGGAAT 300

GCCACTCGGA TTGGAAGATT CGCTAACTAT CTTCGGAACC TCCTCCCCTC GAATGACCCA 360

GTTGTCATGG AGATGGCATC CAAGGCCATT GGCCGCCTCG CCATGGCAGG GGACACTTTT 420

ACGGCTGAGT ATGTGGAGTT TGAGGTGAAG CGAGCCTTGG AGTGGCTGGG TGCTGACCGC 480

AACGAGGGCC GGAGACACGC CGCTGTTCTG GTTCTCCGTG AGCTGGCCAT CAGCGTCCCC 540

ACCTTCTTCT TCCAGCAAGT GCAGCCCTTC TTTGACAACA TTTTTGTGGC CGTGTGGGAC 600

CCCAAACAGG CCATCCGTGA GGGAGCCGTG GCCGCCCTTC GTGCCTGCCT GATTCTCACC 660

ACGCAGCGTG AGCCGAAGGA GATGCAGAAG CCTCAGTGGT ACCGGCACAC GTTTGAAGAA 720

GCAGAGAAAG GGTTTGATGA GACATTGGCC AAGGAGAAAG GCATGAATCG GGATGATCGC 780

ATCCACGGAG CCTTGCTGAT CCTCAACGAG TTGGTCCGAA TCAGCAGCAT GGAGGGAGAG 840

CGCCTGAGAG AAGAAATGGA AGAAATCACA CAGCAGCAGC TCGTGCACGA CAAGTACTGC 900

AAGGACCTCA TGGGCTTCGG GACGAAACCT CGCCACATCA CCCCCTTCAC CAGTTTCCAG 960

GCCGTCCAGC CCCCGCAGTC CAATGCCTTG GTGGGACTGC TGGGGTACAG CTCTCACCAA 1020

GGCCTCATGG GGTTCGGGGC TTCCCCCAGC CCAGCGAAGT CCACCCTGGT GGAGAGTCGG 1080

TGTTGCAGAG ACCTGATGGA GGAGAAATTT GATCAGGTGT GCCAGTGGGT GCTGAAATGC 1140

AGGAACAGCA AGAACTCACT GATCCAGATG ACAATCCTTA ATCTGTTGCC CCGCCTGGCC 1200

GCGTTTCGAC CTTCTGCCTT CACAGATACC CAGTACCTCC AAGATACCAT GAACCATGTC 1260

TTAAGCTGTG TCAAGAAGGA GAAGGAACGT ACAGCAGCCT TCCAAGCCCT GGGGCTGCTT 1320

TCTGTGGCTG TGAGATCTGA GTTTAAGGTC TATTTACCTC GTGTGCTGGA CATCATCCGT 1380

GCAGCCCTAC CCCCTAAGGA CTTTGCCCAT AAGAGACAGA AGGCCATGCA GGTGGATGCC 1440

ACAGTGTTCA CCTGCATCAG CATGCTGGCC CGGGCAATGG GGCCAGGCAT CCAACAGGAT 1500

ATCAAGGAGC TGCTGGAGCC CATGCTGGCA GTGGGACTGA GCCCTGCCCT CACTGCTGTG 1560

CTGTATGACC TGAGCCGTCA GATTCCGCAG CTGAAGAAGG ACATCCAGGA TGGGCTCCTG 1620

AAGATGCTGT CCCTGGTCCT GATGCACAAA CCCCTCCGGC ATCCAGGCAT GCCCAAGGGC 1680

CTGGCCCATC AGCTAGCTTC CCCTGGCCTC ACAGCCCTGC CTGAGGCCAG CGATGTCGGC 1740

AGCATTACTC TTGCCCTGCG AACCCTTGGC AGCTTTGAGT TTGAAGGCCA CTCTCTGACC 1800

CAGTTCGTCC GCCACTGTGC GGATCATTTC CTAAACAGCG AGCACAAGGA GATCCGCATG 1860

GAAGCTGCCC GCACCTGCTC CCGCCTGCTC ACGCCCTCTG TCCACCTCAT TAGCGGCCAC 1920

GCTCACGTGG TTAGCCAGAC TGCAGTGCAA GTCGTGGCAG ACGTGCTCAG CAAACTGCTC 1980

GTGGTTGGGA TAACAGATCC TGACCCTGAC ATCCGCTACT GTGTCTTGGC ATCCCTGGAT 2040

GAGCGCTTTG ATGCACACCT GGCCCAGGCA GAGAATTTGC AGGCCCTGTT TGTGGCCCTG 2100

AACGACCAGG TGTTTGAGAT CCGGGAGCTG GCCATCTGCA CCGTGGGCCG GCTCAGTAGC 2160

ATGAACCCAG CCTTCGTCAT GCCTTTCCTG CGCAAGATGC TTATCCAGAT TTTGACGGAG 2220

CTGGAGCACA GCGGCATTGG AAGAATCAAA GAGCAGAGTG CCCGCATGCT GGGACACCTG 2280

GTCTCCAATG CACCCCGGCT CATCCGCCCC TACATGGAGC CCATTCTGAA GGCTTTAATT 2340

TTGAAACTGA AAGATCCGGA CCCTGATCCA AACCCAGGTG TGATCAATAA TGTCTTGGCT 2400

ACAATAGGAG AATTGGCTCA GGTTAGTGGC CTAGAAATGA GGAAGTGGGT GGATGAACTC 2460

TTTATCATCA TCATGGACAT GCTCCAGGAC TCCTCGCTGT TGGCCAAAAG GCAGGTGGCT 2520

CTGTGGACCC TGGGACAGTT GGTGGCCAGC ACTGGCTATG TAGTGGAGCC CTACAGGAAG 2580

TACCCCACTC TGCTTGAGGT CCTGCTGAAT TTTCTGAAGA CTGAGCAGAA CCAGGGTACA 2640

CGGAGAGAGG CTATCCGTGT GTTGGGGCTT TTGGGGGCCC TGGATCCCTA CAAGCACAAA 2700

GTAAACATTG GCATGATTGA CCAGTCCCGC GACGCTTCTG CTGTCAGCCT GTCTGAATCC 2760

AAGTCAAGTC AGGATTCCTC CGACTACAGC ACCAGCGAGA TGCTGGTCAA CATGGGCAAC 2820

CTGCCCCTGG ATGAGTTCTA CCCTGCCGTG TCCATGGTGG CGCTGATGCG GATCTTCCGA 2880

GACCAGTCCC TCTCGCACCA TCACACCATG GTTGTCCAGG CCATCACCTT CATCTTCAAG 2940

TCCCTGGGCC TCAAGTGTGT GCAGTTCCTG CCTCAGGTCA TGCCCACATT CCTCAATGTC 3000

ATTCGGGTCT GCGATGGGGC CATCCGGGAA TTCCTGTTCC AGCAGCTGGG AATGCTGGTG 3060

TCCTTTGTGA AGAGCCACAT CCGACCTTAC ATGGATGAAA TAGTCACCCT CATGAGAGAA 3120

TTCTGGGTCA TGAACACCTC GATCCAGAGC ACAATCATCC TTCTCATTGA GCAAATAGTG 3180

GTAGCTCTTG GGGGTGAATT TAAGCTCTAC CTGCCCCAGC TGATCCCACA CATGCTACGT 3240

GTCTTCATGC ATGACAACAG CCCAGGTCGC ATCGTCTCCA TCAAGCTGTT GGCCGCCATC 3300

CAGCTGTTTG GTGCCAACCT GGATGACTAT CTGCATTTGT TGTTGCCCCC TATCGTGAAG 3360

CTGTTTGACG CCCCGGAAGT CCCACTGCCA TCTCGGAAGG CAGCATTAGA GACAGTGGAC 3420

CGCCTGACAG AGTCCCTGGA CTTCACTGAC TACGCCTCCC GGATCATTCA TCCAATTGTT 3480

CGAACGCTGG ACCAGAGTCC GGAACTGCGT CCCACGGCCA TGGACACGTT GTCTTCGCTG 3540

GTCTTCCAAC TGGGGAAGAA GTACCAGATT TTCATTCCAA TGGTGAACAA AGTCCTGGTG 3600

CGACACCGAA TCAACCATCA GCGCTACGAC GTCCTCATCT GCAGAATTGT CAAGGGATAC 3660

ACCCTTGCTG ATGAAGAAGA GGACCCTTTG ATTTACCAGC ATCGAATGCT GAGGAGTGGC 3720

CAGGGGGATG CATTGGCTAG TGGCCCAGTA GAAACAGGGC CCATGAAGAA ACTGCATGTC 3780

AGCACCATCA ACCTCCAAAA GGCCTGGGGA GCTGCCAGAA GGGTGTCCAA AGATGACTGG 3840

CTGGAATGGC TGAGGCGGCT GAGTCTGGAG CTCCTGAAGG ACTCCTCGTC GCCTTCCCTG 3900

CGCTCGTGCT GGGCCCTGGC TCAGGCTTAC AACCCAATGG CCAGGGATCT TTTTAATGCC 3960

GCATTTGTGT CCTGCTGGTC TGAACTGAAT GAAGACCAGC AGGATGAACT CATCAGAAGC 4020

ATCGAGTTGG CCCTCACCTC GCAGGACATC GCTGAAGTCA CGCAGACCCT CTTAAACTTG 4080

GCTGAATTCA TGGAACACAG TGACAAGGGC CCTCTGCCAT TGAGAGACGA CAATGGCATT 4140

GTCCTGCTGG GTGAAAGGGC TGCCAAGTGC CGAGCATATG CCAAAGCACT CCACTACAAA 4200

GAACTGGAGT TCCAGAAAGG TCCCACCCCC GCCATCCTAG AGTCTCTCAT CAGCATTAAT 4260

AATAAGCTCC AGCAGCCGGA GGCAGCCGCG GGGGTCTTAG AGTATGCCAT GAAACACTTC 4320

GGAGAACTGG AGATCCAGGC TACCTGGTAC GAGAAACTGC ACGAGTGGGA GGACGCGCTC 4380

GTGGCCTACG ACAAGAAGAT GGACACCAAC AAGGATGACC CGGAGCTGAT GCTGGGCCGC 4440

ATGCGCTGCC TCGAGGCCCT GGGGGAATGG GGCCAGCTCC ACCAGCAGTG CTGTGAAAAG 4500

TGGACCCTGG TTAATGATGA GACCCAAGCC AAGATGGCCC GCATGGCTGC CGCAGCTGCG 4560

TGGGGTTTAG GTCAGTGGGA TAGCATGGAG GAGTACACCT GTATGATCCC TCGGGACACC 4620

CACGATGGGG CATTTTACAG AGCCGTGCTG GCACTGCATC AGGACCTCTT CTCCTTGGCA 4680

CAGCAGTGCA TCGACAAAGC CAGAGACCTG CTGGATGCCG AGTTAACTGC TATGGCAGGA 4740

GAGAGCTACA GTCGGGCATA TGGGGCTATG GTCTCTTGCC ACATGCTCTC CGAGCTGGAG 4800

GAGGTTATCC AGTACAAACT TGTCCCCGAG CGACGGGAGA TCATCCGCCA GATCTGGTGG 4860

GAGAGACTGC AGGGCTGCCA GCGTATTGTG GAGGACTGGC AGAAAATCCT GATGGTGCGG 4920

TCACTTGTGG TCAGCCCTCA TGAGGACATG AGGACCTGGC TCAAGTATGC CAGCCTGTGC 4980

GGGAAGAGTG GCAGGCTGGC CCTTGCTCAC AAAACCTTGG TGTTGCTCCT GGGAGTTGAT 5040

CCATCTCGGC AACTTGACCA CCCTCTGCCA ACAGTTCACC CTCAGGTGAC CTACGCCTAC 5100

ATGAAAAACA TGTGGAAGAG CGCTCGCAAG ATCGACGCCT TCCAGCACAT GCAGCACTTC 5160

GTACAGACCG TGCAGCAGCA GGCCCAGCAC GCCATCGCCA CCGAGGACCA GCAGCACAAG 5220

CAAGAGCTGC ACAAGCTCAT GGCCCGGTGC TTCCTGAAGC TCGGGGAGTG GCAGCTGAAC 5280

CTGCAGGGCA TCAATGAGAG CACCATCCCC AAGGTGCTGC AGTACTACAG TGCGGCCACG 5340

GAGCACGACC GCAGCTGGTA CAAGGCCTGG CACGCGTGGG CAGTGATGAA CTTTGAGGCT 5400

GTGCTGCACT ACAAACATCA GAACCAAGCC CGTGATGAGA AGAAGAAGCT GCGGCACGCC 5460

AGTGGGGCCA ACATCACCAG CACAAGCACT GCCGCCACCA CAGCGGCCAC TGCCACCGCC 5520

ACCAGCACCG AGGGCAGCAA CAGCGAGAGT GAGGCCGAGA GCACCGAGAA CAGCCCCACT 5580

CCGTCTCCTC TGCAGAAGAA GGTCACTGAG GATTTATCCA AAACCCTCTT GATGTACACC 5640

GTCCCTGCGG TCCAGGGCTT CTTCCGTTCC ATCTCCTTGT CACGAGGCAA CAACCTCCAG 5700

GACACGCTGA GAGTCCTCAC CTTATGGTTT GACTATGGTC ACTGGCCAGA CGTAAATGAA 5760

GCCTTAGTGG AGGGGGTGAA AGCAATTCAG ATTGACACTT GGTTACAGGT TATACCGCAG 5820

CTCATCGCAA GGATCGATAC TCCCAGGCCT TTGGTGGGCC GCCTCATTCA CCAGCTTCTC 5880

ACAGACATTG GCCGGTACCA CCCGCAGGCC CTCATCTACC CCCTGACCGT GGCCTCTAAG 5940

TCCACCACGA CGGCCCGCCA CAACGCAGCC AACAAGATTC TGAAGAACAT GTGCGAGCAC 6000

AGTAATACCC TGGTCCAGCA GGCTATGATG GTGAGCGAGG AGCTAATCCG CGTGGCCATC 6060

CTGTGGCACG AGATGTGGCA CGAAGGCCTG GAAGAAGCGT CTCGTTTGTA CTTTGGGGAA 6120

AGGAACGTGA AAGGCATGTT TGAGGTGCTG GAGCCCCTGC ATGCTATGAT GGAACGGGGC 6180

CCCCAGACTC TGAAGGAAAC ATCTTTTAAT CAGGCGTATG GTCGAGACTT AATGGAGGCC 6240

CAAGAGTGGT GCAGGAAGTA CATGAAATCC GGGAACGTCA AGGACCTCAC CCAAGCCTGG 6300

GACCTCTATT ATCACGTGTT CAGACGAATC TCGAAGCAGC TGCCTCAGCT CACCTCCTTA 6360

GAACTGCAGT ATGTTTCCCC CAAACTTCTT ATGTGCCGGG ACCTTGAATT GGCTGTGCCA 6420

GGGACGTACG ACCCCAACCA GCCGATCATT CGCATTCAGT CCATAGCGCC GTCCCTGCAG 6480

GTCATCACCT CCAAGCAGAG GCCCCGGAAG CTGACACTCA TGGGCAGCAA CGGGCATGAG 6540

TTTGTTTTCC TCCTGAAGGG CCACGAAGAC CTGCGGCAGG ATGAGCGAGT GATGCAGCTC 6600

TTTGGCCTGG TGAACACTCT TCTGGCCAAC GACCCAACGT CTCTTCGCAA GAACCTCAGC 6660

ATCCAGAGAT ACGCTGTCAT CCCCTTATCA ACCAACTCGG GCCTCATCGG CTGGGTCCCC 6720

CACTGCGACA CGCTGCACGC CCTCATCCGG GACTACAGAG AGAAGAAGAA GATCCTTCTC 6780

AACATCGAGC ATCGCATCAT GTTGCGGATG GCACCAGACT ACGATCACCT GACGCTGATG 6840

CAGAAGGTGG AGGTGTTCGA GCACGCCGTC AATAACACGG CCGGCGACGA CCTGGCCAAG 6900

CTGCTGTGGC TGAAGAGCCC CAGCTCCGAG GTGTGGTTTG ACCGAAGAAC CAACTATACC 6960

CGCTCTTTAG CGGTCATGTC CATGGTTGGG TATATTTTGG GCCTGGGAGA TCGACACCCA 7020

TCCAACCTAA TGCTGGACCG GCTGAGTGGG AAGATCCTGC ACATCGACTT TGGGGACTGC 7080

TTTGAGGTTG CTATGACCAG GGAGAAATTC CCAGAGAAGA TTCCATTTAG ACTAACAAGA 7140

ATGCTGACCA ATGCTATGGA GGTTACTGGT CTGGATGGCA ACTATAGAAT CACGTGCCAC 7200

ACGGTGATGG AAGTGCTTCG GGAACACAAG GATAGTGTCA TGGCCGTGCT GGAAGCCTTT 7260

GTCTACGACC CCTTGCTGAA CTGGAGGCTG ATGGACACAA ATACCAAAGG CAACAAGCGG 7320

TCCCGAACAA GGACGGATTC CTACTCTGCT GGACAGTCAG TAGAAATTTT GGACGGTGTG 7380

GAACTTGGGG AACCTGCCCA TAAGAAAACA GGGACCACAG TGCCAGAATC TATTCATTCT 7440

TTCATTGGAG ACGGTTTGGT GAAACCAGAG GCCCTAAATA AGAAAGCTAT TCAAATTATT 7500

AACAGGGTTC GAGACAAGCT CACTGGTCGG GACTTTTCTC ATGACGAAAC CCTGGATGTC 7560

CCAACACAGG TGGAGCTGCT CATCAAACAA GCAACGTCCC ACGAGAACCT CTGTCAATGC 7620

TACATCGGCT GG 7632

Domain Profile

S: 1     iagfderveilaskqkpkklllrGsdgkeypyLvkgkeDlrqdervlqlfslvNtlLakd  60

         i+++++++++++skq+p+kl+l+Gs+g+e+++L+kg+eDlrqderv+qlf+lvNtlLa+d

Q: 2152  IQSIAPSLQVITSKQRPRKLTLMGSNGHEFVFLLKGHEDLRQDERVMQLFGLVNTLLAND  2211

         899*********************************************************

S: 61    ketsrrkLkirtykVvplstrsgliewventvsLkellkklvekkavlldqpisyrykdl  120

         +++ r++L+i++y+V+plst+sgli+wv+++++L++l+++++ekk++ll+        ++

Q: 2212  PTSLRKNLSIQRYAVIPLSTNSGLIGWVPHCDTLHALIRDYREKKKILLN-------IEH  2264

         *************************************************9.......9**

S: 121   stvqarkpklkhlkls..levfkevlenlvpkdllkklllekfpspeewfelrkaytrsl  178

         +++ +++p+++hl+l+  +evf+++++n ++ d l+kll+ k+ps+e+wf++r++ytrsl

Q: 2265  RIMLRMAPDYDHLTLMqkVEVFEHAVNN-TAGDDLAKLLWLKSPSSEVWFDRRTNYTRSL  2323

         ****************************.999****************************

S: 179   AvislvgyiLgLgdrhlenllidqetgevvhidfgvafekaktqlkvpekvPFRLTrniv  238

         Av+s+vgyiLgLgdrh++nl++d+ +g+++hidfg +fe a+t++k+pek+PFRLTr+++

Q: 2324  AVMSMVGYILGLGDRHPSNLMLDRLSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLT  2383

         ************************************************************

S: 239   nalgvtgveGvfrasceavlrvlreskeklltiLevflydplvdwkkkkktsketeeela  298

         na++vtg++G++r++c++v++vlre+k++++++Le+f+ydpl++w+ +++++k+++++++

Q: 2384  NAMEVTGLDGNYRITCHTVMEVLREHKDSVMAVLEAFVYDPLLNWRLMDTNTKGNKRSRT  2443

         ************************************************************

S: 299   ekakaealkikkllskvekaenavatrdlllle  331

         ++++++a +++++l++ve +e+a+++++++++e

Q: 2444  RTDSYSAGQSVEILDGVELGEPAHKKTGTTVPE  2476

         ****************************99987

Domain Sequence
(FASTA)

IQSIAPSLQV ITSKQRPRKL TLMGSNGHEF VFLLKGHEDL RQDERVMQLF GLVNTLLAND 60

PTSLRKNLSI QRYAVIPLST NSGLIGWVPH CDTLHALIRD YREKKKILLN IEHRIMLRMA 120

PDYDHLTLMQ KVEVFEHAVN NTAGDDLAKL LWLKSPSSEV WFDRRTNYTR SLAVMSMVGY 180

ILGLGDRHPS NLMLDRLSGK ILHIDFGDCF EVAMTREKFP EKIPFRLTRM LTNAMEVTGL 240

DGNYRITCHT VMEVLREHKD SVMAVLEAFV YDPLLNWRLM DTNTKGNKRS RTRTDSYSAG 300

QSVEILDGVE LGEPAHKKTG TTVPE 325

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005829	; C:cytosol
GO:0012505	; C:endomembrane system
GO:0005764	; C:lysosome
GO:0016020	; C:membrane
GO:0016605	; C:PML body
GO:0005524	; F:ATP binding
GO:0008144	; F:drug binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0043022	; F:ribosome binding
GO:0001030	; F:RNA polymerase III type 1 promoter DNA binding
GO:0001031	; F:RNA polymerase III type 2 promoter DNA binding
GO:0001032	; F:RNA polymerase III type 3 promoter DNA binding
GO:0071456	; P:cellular response to hypoxia
GO:0031669	; P:cellular response to nutrient levels
GO:0007281	; P:germ cell development
GO:0045792	; P:negative regulation of cell size
GO:0016242	; P:negative regulation of macroautophagy
GO:0051534	; P:negative regulation of NFAT protein import into nucleus
GO:0018105	; P:peptidyl-serine phosphorylation
GO:0018107	; P:peptidyl-threonine phosphorylation
GO:0030838	; P:positive regulation of actin filament polymerization
GO:0010592	; P:positive regulation of lamellipodium assembly
GO:0046889	; P:positive regulation of lipid biosynthetic process
GO:0050731	; P:positive regulation of peptidyl-tyrosine phosphorylation
GO:0051496	; P:positive regulation of stress fiber assembly
GO:0045945	; P:positive regulation of transcription from RNA polymerase III promoter
GO:0045859	; P:regulation of protein kinase activity
GO:0032314	; P:regulation of Rac GTPase activity
GO:0043200	; P:response to amino acid stimulus
GO:0032868	; P:response to insulin stimulus
GO:0031529	; P:ruffle organization
GO:0031929	; P:TOR signaling cascade

KEGG

aml:100471122

;

InterPros

IPR011989	; ARM-like.
IPR016024	; ARM-type_fold.
IPR024585	; DUF3385_TOR.
IPR003152	; FATC.
IPR011009	; Kinase-like_dom.
IPR000403	; PI3/4_kinase_cat_dom.
IPR018936	; PI3/4_kinase_CS.
IPR003151	; PIK-rel_kinase_FAT.
IPR014009	; PIK_FAT.
IPR009076	; Rapamycin-bd_dom.
IPR026683	; TOR/Smg1.

Pfam

PF11865	; DUF3385; 1.
PF02259	; FAT; 1.
PF02260	; FATC; 1.
PF00454	; PI3_PI4_kinase; 1.
PF08771	; Rapamycin_bind; 1.

SMARTs

SM00146

; PI3Kc; 1.

Prosites

PS51189	; FAT; 1.
PS51190	; FATC; 1.
PS00915	; PI3_4_KINASE_1; 1.
PS00916	; PI3_4_KINASE_2; 1.
PS50290	; PI3_4_KINASE_3; 1.

Prints

Created Date

20-Feb-2013