EKS-AIM-00307

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-AIM-00307

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
STE/STE20	312.3	2.7E-93	26	292	267

Status

Unreviewed

Ensembl Protein

ENSAMEP00000010997

UniProt Accession

G1LV96;

Protein Name

Protein Synonyms/Alias

Gene Name

MYO3B

Gene Synonyms/Alias

MYO3B;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSAMEG00000010422	ENSAMEP00000010997	ENSAMET00000011467

Organism

Ailuropoda melanoleuca

Functional Description

Protein Length

1341

Protein Sequence
(FASTA)

KHLYGLFHYN PTMLGLESLP DPTDTWEIIE TIGKGTYGKV YKVTNKRDGS LAAVKILDPI 60

SDMDEEIEAE YSILQFLPNH PNVVKFYGMF YKADHCVGGQ LWLVLELCNG GSVTELVKGL 120

LRCGQRLDEA MISYILYGAL LGLQHLHNNR IIHRDVKGNN ILLTTEGGVK LVDFGVSAQL 180

TSTRLRRNTS VGTPFWMAPE VIACEQQYDS SYDARCDVWS LGITAIELGD GDPPLFDMHP 240

VKTLFKIPRN PPPTLLHPEK WCEEFNHFIS QCLIKDFEKR PSVTHLLDHP FIKGAHGKVL 300

FLQKQLAKVL QDQKHLNPVV KTRHERMHTR RPYHVEDAEK YCLEDDLVNL EVLDEDTIIR 360

QLQKRYVDLL IYTYVGDILI ALNPFQNLSI YSPQFSRLYH GVKRASNPPH IFASADAAYQ 420

CMVTFSKDQC IVISGESGSG KTESAHLIVQ HLTFLGKANN QTLREKILQV NSLVEAFGNA 480

CTAINDNSSR FGKYLEMMFT PTGAVMGARI SEYLLEKSRV IKQAVGEKNF HIFYYIYAGL 540

YHQKKLSEFR LPEEKPPRYI ADETGKVIHD ITSKDSYRRQ FEAIQHCFRI IGFTDKEVQS 600

VYRILAGILN IGNIEFAAIS SQHQTDKSEV PNADALENAA SVLCISPEEL QEALISRCVV 660

TRGETIVRAN TVDGAADVRD AMSKALYGRL FSWIVNRINT LLQPDKNICS ADDGMNVGIL 720

DIFGFENFRR NSFEQLCINI ANEQIQYYFN QHVFALEQME YQNEGIDATP VVYEDNRPLL 780

DMFLQKPLGL LALLDEESRF PQATDQTLVD KFEVNLRSKY FWRPKGVELC FGILHYAGKV 840

LYDASGVLEK NRDTLPADVV VVLRMSENKL LQQLFSIPLT KTGNLAQTRA RITAASRSLP 900

PHFSAGRTKV DTLEVIRHPE ETTNMKRQTM ASYFRYSLMD LLSKMVVGQP HFVRCIKPND 960

DREALKFSRE SVLAQLRSTG ILETVSIRRQ GYSHRILFEE FVKRYYYLAF KAHETPLASK 1020

ESCVAILEKS RLDHWVLGKT KVFLKYYHVE QLNLLLQEVI GRVVVLQAYA KGWLGTRRYK 1080

RIREKREKGA IAIQSAWRGY DARKKFKKIS NRRSKSAVPI QAGHPSDQSR DLQPTVAEDS 1140

EESAQDQDYS EPGDHTVLRG SIDHKSSPQT EFNGGHAVTS SNSPADTEKN RHPQAQCSPK 1200

GCDVSAGHSN KHSISGTDLP SSQTCLAAPG CPGWSPLREA PTKPVSENGL TQKQRTPRRR 1260

CQQPKMLSSP EDTMYYNQLN GTLEYQGSKR KPRKLGQIKV LDGEDEYYKS LSPVDSIPED 1320

DNPSCPFFSS STSKGASFAQ H 1341

Nucleotide Sequence
(FASTA)

AAACATCTGT ATGGATTGTT TCATTACAAC CCCACGATGC TTGGACTTGA ATCACTTCCA 60

GATCCCACTG ATACCTGGGA AATTATAGAG ACCATAGGTA AAGGCACCTA TGGCAAGGTC 120

TACAAAGTAA CTAACAAGAG AGATGGGAGC CTGGCTGCAG TAAAAATTTT GGATCCAATC 180

AGTGATATGG ATGAAGAGAT TGAAGCAGAG TACAGCATTT TGCAGTTTCT TCCAAATCAT 240

CCCAACGTTG TAAAGTTTTA TGGGATGTTT TACAAAGCAG ATCACTGTGT GGGAGGACAG 300

CTGTGGCTGG TCCTGGAGTT GTGTAATGGG GGCTCAGTCA CCGAGCTTGT CAAAGGTCTA 360

CTCAGGTGCG GCCAGCGGTT GGATGAAGCA ATGATCTCAT ACATCTTATA TGGGGCCCTC 420

TTGGGCCTTC AGCATTTGCA CAATAACCGA ATCATCCACC GTGATGTCAA GGGGAATAAC 480

ATTCTTCTGA CAACAGAAGG AGGAGTTAAG CTCGTTGACT TTGGTGTCTC AGCTCAACTC 540

ACCAGTACAC GTTTACGGAG AAACACATCT GTTGGCACCC CATTCTGGAT GGCTCCTGAG 600

GTCATTGCTT GTGAGCAGCA GTATGACTCC TCCTATGACG CTCGGTGTGA CGTCTGGTCG 660

TTGGGGATCA CAGCTATTGA ACTGGGGGAT GGAGACCCTC CCCTCTTTGA CATGCATCCT 720

GTGAAAACGC TTTTTAAGAT TCCAAGAAAT CCTCCACCTA CTTTACTTCA TCCGGAAAAA 780

TGGTGTGAGG AATTCAATCA CTTTATTTCA CAGTGTCTTA TTAAGGATTT TGAAAAGCGG 840

CCTTCTGTCA CACATCTCCT CGACCACCCA TTTATTAAAG GAGCCCACGG GAAGGTTTTG 900

TTTCTGCAAA AACAGCTGGC CAAGGTCCTC CAAGATCAGA AGCATCTAAA CCCTGTTGTT 960

AAAACCAGGC ATGAAAGAAT GCATACCAGA AGACCCTATC ATGTGGAAGA TGCTGAAAAA 1020

TACTGCCTTG AGGATGATTT GGTCAATTTA GAGGTTCTGG ATGAGGATAC AATTATTCGT 1080

CAGTTGCAAA AGCGTTATGT GGACTTGCTG ATTTACACAT ATGTTGGAGA CATCTTAATT 1140

GCCTTAAACC CCTTCCAGAA CCTAAGCATA TACTCTCCAC AGTTTTCCAG GCTTTATCAT 1200

GGGGTAAAAC GTGCCTCAAA TCCCCCCCAC ATATTTGCAT CAGCAGATGC TGCTTACCAA 1260

TGTATGGTTA CTTTCAGCAA AGACCAGTGC ATTGTCATCA GTGGAGAAAG TGGCTCTGGG 1320

AAGACAGAAA GTGCCCACCT GATTGTTCAG CATTTGACTT TCTTGGGAAA GGCCAATAAT 1380

CAGACCTTGA GAGAGAAAAT TCTGCAAGTC AACTCCCTGG TGGAAGCCTT TGGAAATGCA 1440

TGCACTGCCA TCAATGACAA TTCCAGCCGT TTTGGAAAAT ATCTGGAAAT GATGTTTACA 1500

CCAACTGGAG CTGTGATGGG GGCAAGAATC TCTGAATATC TCCTTGAAAA ATCCAGAGTT 1560

ATAAAACAGG CAGTGGGAGA GAAAAATTTT CACATATTTT ACTACATTTA TGCTGGTCTT 1620

TATCACCAGA AGAAACTTTC TGAGTTCAGA CTTCCTGAGG AAAAGCCTCC TAGGTATATA 1680

GCTGATGAAA CTGGAAAGGT GATACACGAC ATAACTTCCA AGGACTCTTA CAGAAGACAA 1740

TTTGAAGCAA TTCAACATTG CTTCAGGATT ATAGGGTTCA CTGACAAGGA GGTGCAATCA 1800

GTGTACAGAA TTTTGGCTGG GATTTTGAAT ATTGGAAACA TCGAATTTGC AGCTATTTCC 1860

TCTCAACATC AAACTGATAA AAGTGAGGTG CCCAATGCTG ATGCTTTGGA AAATGCTGCC 1920

TCCGTTCTCT GCATCAGCCC TGAAGAACTC CAAGAGGCCC TTATCTCACG CTGTGTGGTC 1980

ACCCGCGGTG AGACCATCGT CCGAGCCAAT ACTGTCGACG GGGCTGCGGA TGTCCGAGAT 2040

GCCATGTCCA AAGCCCTGTA CGGGAGGCTC TTCAGTTGGA TTGTCAACCG AATCAATACA 2100

CTCCTGCAGC CAGACAAAAA CATATGTAGT GCAGATGATG GTATGAATGT GGGCATCTTG 2160

GATATTTTTG GATTTGAGAA CTTTCGAAGA AATTCATTTG AACAGCTCTG CATAAACATT 2220

GCCAATGAGC AAATCCAGTA CTATTTCAAC CAGCACGTTT TCGCTCTTGA GCAGATGGAA 2280

TATCAGAATG AAGGCATTGA TGCTACACCC GTGGTATATG AGGACAATCG CCCACTCCTG 2340

GACATGTTCC TCCAGAAACC CCTGGGACTG CTTGCGCTTT TGGATGAGGA AAGTCGATTT 2400

CCCCAAGCAA CTGATCAGAC CCTGGTTGAT AAATTCGAAG TTAATCTACG AAGCAAATAC 2460

TTCTGGAGGC CTAAAGGAGT GGAGCTGTGC TTCGGCATTC TGCACTATGC TGGGAAGGTA 2520

TTATATGATG CTTCTGGGGT TCTTGAGAAA AACAGAGACA CTCTTCCTGC TGATGTGGTT 2580

GTGGTCCTGA GAATGTCTGA AAACAAGCTT CTGCAGCAAC TCTTCTCCAT TCCTTTGACC 2640

AAAACAGGTA ACTTGGCCCA GACAAGAGCC AGGATAACAG CAGCCTCAAG ATCTTTGCCT 2700

CCGCATTTCA GTGCTGGGAG AACCAAGGTG GACACTCTGG AGGTGATACG ACATCCAGAA 2760

GAAACCACCA ACATGAAGAG ACAGACCATG GCTTCTTACT TCCGGTATTC TCTGATGGAT 2820

CTGCTCTCCA AAATGGTGGT CGGACAGCCC CACTTTGTGC GCTGCATTAA ACCCAATGAT 2880

GACCGAGAGG CCCTGAAGTT CTCCCGAGAG AGTGTGCTGG CCCAGCTCCG CTCCACAGGG 2940

ATCCTGGAGA CAGTCAGCAT CCGCAGGCAG GGGTATTCCC ACCGCATCCT CTTTGAAGAG 3000

TTTGTGAAAA GGTATTATTA CTTGGCATTC AAAGCACATG AAACACCTCT TGCTAGCAAA 3060

GAGAGCTGTG TTGCTATCTT GGAAAAATCC AGATTAGATC ACTGGGTTCT GGGAAAAACA 3120

AAGGTTTTTC TCAAATATTA CCATGTTGAG CAGTTAAATT TGCTGCTGCA AGAAGTCATA 3180

GGCAGAGTGG TTGTGCTGCA GGCATATGCC AAGGGGTGGC TTGGAACCAG GAGATACAAA 3240

AGAATCAGAG AGAAGAGAGA GAAGGGGGCC ATTGCCATCC AGTCAGCCTG GAGAGGATAT 3300

GATGCTCGGA AGAAATTTAA GAAAATAAGC AACAGAAGGA GTAAGTCTGC GGTTCCTATT 3360

CAAGCAGGGC ACCCTTCAGA CCAAAGCAGA GATCTGCAGC CCACTGTCGC GGAGGATAGC 3420

GAGGAAAGTG CCCAGGATCA AGACTACAGT GAGCCTGGTG ACCACACAGT TTTGAGGGGC 3480

TCTATAGATC ATAAAAGCAG TCCACAAACA GAATTCAACG GTGGCCATGC AGTGACTTCA 3540

AGCAACTCTC CTGCTGACAC TGAGAAAAAT CGGCATCCAC AAGCCCAGTG TTCTCCAAAA 3600

GGGTGTGATG TCTCTGCAGG ACATTCAAAT AAGCACTCCA TTTCTGGGAC TGATCTGCCA 3660

TCTTCTCAGA CGTGCCTTGC TGCCCCAGGT TGCCCAGGAT GGAGCCCCTT GAGAGAAGCC 3720

CCTACAAAAC CTGTTTCAGA AAATGGTCTT ACACAGAAGC AGCGAACACC TCGCCGAAGA 3780

TGTCAGCAGC CCAAAATGTT GAGTAGCCCT GAGGACACCA TGTACTATAA CCAGTTAAAT 3840

GGAACTCTAG AATATCAAGG GAGCAAGAGG AAGCCAAGAA AACTTGGCCA AATCAAAGTG 3900

CTTGATGGGG AAGATGAATA TTACAAATCT TTGTCACCTG TGGACTCTAT TCCTGAGGAC 3960

GACAACCCAT CCTGCCCTTT CTTTTCTTCC TCAACCTCAA AAGGAGCATC TTTTGCTCAG 4020

CAC 4023

Domain Profile

S: 1     yelleeigkGalgkvylarekktgelvaikkinlekqekleelqkeisvlkkl.khpniv  59

         +e++e+igkG++gkvy+ ++k+ g+l+a+k+++  + ++ ee++ e+s+l+ l +hpn+v

Q: 26    WEIIETIGKGTYGKVYKVTNKRDGSLAAVKILDPIS-DMDEEIEAEYSILQFLpNHPNVV  84

         799******************************998.99************98356****

S: 60    eylesflk.....eeelwlvmeylagGslsdlvk..eelkselkEeqiayilrevlkaLe  112

         +++++f+k       +lwlv+e+++gGs+++lvk    + ++l+E  i+yil ++l +L+

Q: 85    KFYGMFYKadhcvGGQLWLVLELCNGGSVTELVKglLRCGQRLDEAMISYILYGALLGLQ  144

         *******99888889*******************777899********************

S: 113   ylHskkviHrdikakniLlteegeVkLsdfgvaaqlektrkkrktvvgtpywmAPEviaq  172

         +lH++++iHrd+k++niLlt+eg VkL+dfgv+aql++tr +r+t vgtp+wmAPEvia+

Q: 145   HLHNNRIIHRDVKGNNILLTTEGGVKLVDFGVSAQLTSTRLRRNTSVGTPFWMAPEVIAC  204

         ************************************************************

S: 173   e...ekgYdekaDiwslGItaielaegepPfkdleplkallkilkneppklkskkkfske  229

         e   +++Yd+++D+wslGItaiel +g+pP++d++p+k l+ki++n+pp+l +++k+++e

Q: 205   EqqyDSSYDARCDVWSLGITAIELGDGDPPLFDMHPVKTLFKIPRNPPPTLLHPEKWCEE  264

         9888899*****************************************************

S: 230   fkefvekclqknpekRpsasellkhkFl  257

         f++f+++cl k++ekRps+++ll+h+F+

Q: 265   FNHFISQCLIKDFEKRPSVTHLLDHPFI  292

         ***************************7

Domain Sequence
(FASTA)

WEIIETIGKG TYGKVYKVTN KRDGSLAAVK ILDPISDMDE EIEAEYSILQ FLPNHPNVVK 60

FYGMFYKADH CVGGQLWLVL ELCNGGSVTE LVKGLLRCGQ RLDEAMISYI LYGALLGLQH 120

LHNNRIIHRD VKGNNILLTT EGGVKLVDFG VSAQLTSTRL RRNTSVGTPF WMAPEVIACE 180

QQYDSSYDAR CDVWSLGITA IELGDGDPPL FDMHPVKTLF KIPRNPPPTL LHPEKWCEEF 240

NHFISQCLIK DFEKRPSVTH LLDHPFI 267

Keyword

ATP-binding; Complete proteome; Motor protein; Myosin; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>

Gene Ontology

GO:0016459	; C:myosin complex
GO:0005524	; F:ATP binding
GO:0003774	; F:motor activity
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR000048	; IQ_motif_EF-hand-BS.
IPR011009	; Kinase-like_dom.
IPR001609	; Myosin_head_motor_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00612	; IQ; 1.
PF00063	; Myosin_head; 1.
PF00069	; Pkinase; 1.

SMARTs

SM00015	; IQ; 2.
SM00242	; MYSc; 1.
SM00220	; S_TKc; 1.

Prosites

PS50096	; IQ; 2.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

PR00193

; MYOSINHEAVY.

Created Date

20-Feb-2013