EKS-AIM-00190

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-AIM-00190

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/MAST	527.2	9.2E-159	367	640	274

Status

Unreviewed

Ensembl Protein

ENSAMEP00000011585

UniProt Accession

G1LWY2;

Protein Name

Protein Synonyms/Alias

Gene Name

MAST3

Gene Synonyms/Alias

MAST3;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSAMEG00000011019	ENSAMEP00000011585	ENSAMET00000012077

Organism

Ailuropoda melanoleuca

Functional Description

Protein Length

1302

Protein Sequence
(FASTA)

EPSLLRRRGL QKELSLPRRG RGCRSGNRKS LVVGTPSPTL SRPLSPLSVP TAGNSPLESP 60

RNFSAASAVN FPFARRADGR RWSLASLPSS GYGTNTPSST VSSSSSSRER LHQLPFQPTP 120

DELCFLSKHF RSSESVVDEE GGHRSPHLRP RSRSLSPGRT TGTFDNEIVM MNHVYRERFP 180

KATAQMEGRL QEFLAAFAPG ARLALADGVL GFIHHQIIEL ARDCLAKSGE ALVTSRYFLE 240

MQEKLERLLQ DAHERSDSEE VGFIVQLVRK LLIIISRPAR LLECLEFDPE EFYHLLEAAE 300

GQAREGQGIK TDLPQYIIGQ LGLAKDPLEE MVPLSHLEGE GQPPAPESPE SRSLVGPSRR 360

KPCESDFETI KLISNGAYGA VYLVRHRDTR QRFAIKKINK QNLILRNQIQ QVFVERDILT 420

FAENPFVVSM FCSFETRRHL CMVMEYVEGG DCATLLKNMG PLPVDMARMY FAETVLALEY 480

LHNYGIVHRD LKPDNLLITS LGHIKLTDFG LSKIGLMSMA TNLYEGHIEK DTREFVDKQV 540

CGTPEYIAPE VIFRQGYGKP VDWWAMGVVL YEFLVGCVPF FGDTPEELFG QVVSDEIMWP 600

EGDEALPADA QDLITRLLRQ SPLDRLGTGG THEVKQHPFF WTLDWAGLLR HKAEFVPQLE 660

AEDDTSYFDT RSERYRHLGS EDEETNDEES STEIPQFSSC SHRFSKVYSS SEFLAAQPTP 720

TFAERSFSED REEGWERGGE GEFGRRFSMC CRLRSWTSSG PSGQSSSSQP ERGPSPSLLN 780

TISLDTMPKF AFSSEDEGAS PASVGPKRPI FILGEPDPPP AATPVMPKPS SLSADTAALS 840

HARLRSNSTG ARHSTPRALD AGRGRRLGGS RDPAPEKSRV SPSGGRVPKS ASVSALSLII 900

TADDGSGGPL MSPLSPRSLS SNPSSRDSSP SRDPSPVCGS LRPPIVIHSS GKKYGFSLRA 960

IRVYMGDSDV YTVHHVVWSV EEGSPAQEAG LRAGDLITHI NGESVLGLVH MDVVELLLKS 1020

GNKVALRTTA LENTSIKVGP ARKNVAKGRM ARRSKRSRRR ETQDRRKSLF KKISKQSSVL 1080

HTSRSFSSGL HHSLSSSESL PGSPTHSLSP SPTTPCRSPA PDAPADTTSP PSASPSSSSP 1140

ASPAAGGHTR PSSLHGLAAK LGPPRPKTGR RKSTSSIPPS PLACPPVPVP PPRSPSPLPG 1200

HPPAPARSPR LRRGQSADKL GSGERLEGEL GRRGRGPDSE LVVMRRLHLS ERRDSFKKQE 1260

AVQEVSFDEP PEEAMGPFTS VPQIAVEGAE AVLGALGPAG KD 1302

Nucleotide Sequence
(FASTA)

GAGCCGAGCC TCCTGCGGCG CCGAGGGCTC CAGAAGGAGC TGAGCCTGCC ACGCCGGGGA 60

CGTGGCTGTC GCAGCGGGAA CCGCAAAAGT CTGGTGGTAG GAACGCCCTC GCCAACCCTT 120

TCCCGGCCCC TGTCTCCGCT CTCCGTCCCC ACAGCAGGCA ACAGCCCTCT TGAGAGTCCT 180

CGGAACTTCT CAGCTGCGTC TGCTGTGAAC TTCCCCTTTG CCCGAAGGGC TGACGGCAGA 240

AGATGGTCCC TTGCGTCCCT CCCATCTTCT GGCTATGGAA CCAACACGCC CAGCTCCACC 300

GTCTCGTCAA GCTCATCCTC CCGGGAGCGC CTCCACCAGC TTCCTTTCCA ACCGACGCCG 360

GATGAACTAT GCTTCCTGTC CAAGCATTTC CGCAGCTCAG AGAGCGTGGT TGACGAGGAA 420

GGCGGCCACC GCTCACCCCA CCTTCGTCCC CGTTCCCGCA GTCTCAGCCC GGGACGCACA 480

ACAGGGACCT TCGACAATGA AATCGTCATG ATGAATCATG TGTACCGGGA GAGGTTCCCC 540

AAGGCCACGG CACAGATGGA AGGCCGTCTG CAGGAGTTCC TGGCTGCTTT TGCGCCCGGC 600

GCCCGGCTGG CACTGGCCGA CGGCGTCCTG GGCTTCATCC ACCACCAGAT CATTGAGCTG 660

GCCCGCGACT GCCTGGCCAA GTCTGGAGAG GCGCTCGTCA CCTCCCGCTA CTTCCTGGAG 720

ATGCAGGAGA AGCTGGAGAG GCTGCTGCAA GATGCCCACG AGCGCTCGGA CAGTGAGGAG 780

GTGGGCTTCA TCGTCCAGCT TGTCCGGAAG CTGCTTATCA TCATCTCAAG GCCAGCGAGG 840

CTCCTTGAGT GCCTGGAGTT TGACCCTGAG GAGTTTTATC ACCTGCTGGA GGCTGCCGAG 900

GGCCAGGCCC GAGAGGGCCA GGGCATCAAG ACGGACCTGC CGCAGTACAT CATTGGGCAG 960

CTGGGCCTGG CTAAGGACCC CCTCGAGGAG ATGGTGCCTC TGAGTCACCT GGAAGGGGAA 1020

GGACAGCCTC CAGCACCCGA GTCCCCGGAG AGCCGTTCCC TCGTCGGCCC ATCACGGAGG 1080

AAGCCATGTG AGAGTGACTT CGAGACCATC AAACTCATTA GCAACGGAGC CTACGGGGCT 1140

GTCTACCTGG TACGCCACCG AGACACACGG CAGCGCTTTG CCATCAAGAA GATCAACAAG 1200

CAGAACCTGA TTCTGCGTAA CCAGATCCAG CAGGTCTTCG TGGAGCGCGA CATCCTCACC 1260

TTCGCCGAGA ACCCGTTTGT GGTCAGCATG TTCTGCTCCT TCGAGACCCG GCGCCACTTG 1320

TGTATGGTCA TGGAGTATGT GGAAGGCGGC GACTGTGCCA CGCTCCTGAA GAACATGGGC 1380

CCCCTGCCCG TGGACATGGC CCGCATGTAC TTCGCCGAGA CGGTGCTGGC GCTCGAATAC 1440

TTGCACAACT ATGGGATCGT GCACCGTGAC CTCAAGCCTG ACAACCTGCT TATCACCTCA 1500

TTGGGCCACA TCAAGCTGAC CGACTTCGGC CTGTCCAAGA TTGGGCTCAT GAGCATGGCC 1560

ACCAACCTCT ACGAGGGCCA CATCGAGAAG GACACCCGGG AGTTCGTGGA CAAGCAGGTG 1620

TGCGGGACGC CTGAGTACAT CGCGCCCGAG GTGATCTTCC GCCAGGGCTA CGGGAAGCCA 1680

GTGGACTGGT GGGCCATGGG TGTTGTCCTC TATGAATTCC TGGTGGGCTG TGTGCCTTTC 1740

TTCGGAGATA CCCCCGAGGA ACTCTTTGGC CAGGTGGTCA GTGATGAGAT CATGTGGCCA 1800

GAAGGAGATG AGGCCCTCCC AGCTGATGCC CAGGACCTCA TCACCAGGCT GCTCCGACAG 1860

AGCCCATTGG ACCGTCTGGG CACGGGTGGC ACCCACGAGG TAAAGCAGCA CCCCTTCTTC 1920

TGGACGCTGG ACTGGGCCGG GCTTCTGCGA CACAAAGCTG AGTTTGTGCC ACAGCTTGAA 1980

GCCGAGGACG ACACCAGCTA CTTTGACACA CGCTCGGAAC GTTACCGCCA CCTGGGCTCG 2040

GAGGACGAGG AGACCAATGA TGAGGAGTCA TCCACAGAGA TCCCTCAGTT TTCGTCGTGT 2100

TCCCACCGGT TCAGCAAGGT CTACAGCAGC TCCGAGTTCC TGGCCGCCCA GCCCACCCCA 2160

ACCTTCGCTG AACGGAGCTT CAGTGAGGAC CGGGAGGAAG GGTGGGAGCG CGGTGGCGAG 2220

GGCGAGTTTG GCCGCCGCTT CAGCATGTGT TGCAGACTGA GGTCCTGGAC ATCCTCTGGT 2280

CCCTCCGGCC AGTCATCTTC TTCCCAGCCG GAGCGGGGCC CCAGCCCATC GCTCTTGAAT 2340

ACTATTAGCC TGGATACAAT GCCCAAGTTT GCCTTCTCGT CGGAGGATGA GGGAGCCAGC 2400

CCAGCCTCTG TGGGCCCCAA GAGGCCCATC TTCATTCTGG GGGAGCCTGA TCCACCCCCA 2460

GCAGCCACCC CAGTGATGCC CAAGCCCTCA AGCCTTTCTG CCGACACAGC CGCCCTCAGC 2520

CACGCGCGCC TGCGAAGCAA CAGCACTGGC GCCCGGCACT CGACACCACG GGCCCTGGAT 2580

GCCGGTCGGG GCCGCCGCCT TGGGGGCTCA AGAGACCCAG CTCCCGAGAA GTCTCGGGTC 2640

TCCCCCAGTG GGGGCCGCGT GCCCAAGTCT GCCTCAGTGT CTGCCCTATC CCTCATCATC 2700

ACAGCCGATG ATGGCAGCGG TGGCCCGCTC ATGAGCCCTC TGTCCCCACG CTCACTGTCC 2760

TCGAACCCAT CATCCCGAGA CTCCTCTCCG AGCCGAGACC CGTCCCCCGT GTGTGGCAGC 2820

CTGCGGCCCC CCATCGTCAT CCACAGCTCA GGCAAGAAGT ACGGCTTCAG CCTGCGGGCC 2880

ATCCGCGTCT ACATGGGTGA CAGCGATGTC TACACCGTGC ACCATGTTGT CTGGAGCGTG 2940

GAGGAGGGAA GCCCTGCCCA GGAGGCAGGC CTGCGAGCTG GGGACCTCAT CACCCACATC 3000

AACGGGGAGT CAGTCCTGGG GCTGGTGCAC ATGGACGTCG TTGAGCTGCT GCTGAAGAGC 3060

GGCAACAAGG TCGCCCTACG GACCACAGCC TTGGAGAACA CCTCCATCAA GGTGGGCCCC 3120

GCCCGGAAGA ATGTGGCCAA GGGCCGCATG GCTCGCAGGA GCAAGCGGAG CCGCCGGCGG 3180

GAGACGCAGG ACCGGCGGAA GTCGCTCTTC AAGAAGATCT CAAAACAGTC CTCCGTGCTG 3240

CACACAAGCC GCAGCTTCTC TTCCGGCCTC CACCACTCCC TGTCGTCCAG CGAGAGCCTC 3300

CCGGGGTCGC CCACCCACAG CCTCTCCCCC AGCCCCACCA CGCCTTGCCG CAGCCCAGCT 3360

CCTGATGCCC CAGCAGACAC CACATCCCCT CCCAGTGCCT CCCCGAGCTC CAGCAGCCCT 3420

GCCTCTCCTG CCGCTGGTGG CCACACCCGC CCTAGCTCCC TGCATGGCCT GGCCGCCAAG 3480

CTCGGGCCAC CCCGCCCCAA GACCGGCCGC CGCAAGTCTA CCAGCAGTAT CCCGCCCTCC 3540

CCACTGGCCT GCCCACCTGT GCCTGTGCCC CCACCCCGCT CACCCTCTCC CCTCCCTGGA 3600

CACCCACCCG CACCCGCCCG GTCTCCGCGG TTGCGCCGGG GCCAGTCAGC TGACAAGCTG 3660

GGTTCGGGTG AACGGCTGGA GGGGGAGCTG GGGCGCCGCG GCCGCGGGCC AGACTCGGAG 3720

CTGGTGGTCA TGCGGCGGCT ACACCTGTCC GAGCGCCGAG ACTCCTTCAA GAAGCAGGAG 3780

GCGGTGCAGG AGGTGAGCTT TGATGAGCCG CCCGAAGAGG CCATGGGGCC GTTCACTTCC 3840

GTACCACAGA TTGCCGTGGA GGGCGCAGAG GCTGTGCTGG GAGCCCTTGG ACCTGCCGGG 3900

AAGGAC 3906

Domain Profile

S: 1     feiiklisrGayGavylvrhketrkrfavkkikkqdlilknqvqqvfaerdilalaenpf  60

         fe+iklis+GayGavylvrh++tr+rfa+kki+kq+lil+nq+qqvf+erdil++aenpf

Q: 367   FETIKLISNGAYGAVYLVRHRDTRQRFAIKKINKQNLILRNQIQQVFVERDILTFAENPF  426

         99**********************************************************

S: 61    vvslyysletrrnlylvmeyveGGdvksllkniGaldvemarlyiaevvlaleylhryGi  120

         vvs+++s+etrr+l++vmeyveGGd+++llkn+G+l+v+mar+y+ae+vlaleylh+yGi

Q: 427   VVSMFCSFETRRHLCMVMEYVEGGDCATLLKNMGPLPVDMARMYFAETVLALEYLHNYGI  486

         ************************************************************

S: 121   vhrdlkPdnllitseGhikltdfGlskvglmslttnlyegyidkdarefldkqvcgtPey  180

         vhrdlkPdnllits GhikltdfGlsk+glms++tnlyeg+i+kd+ref+dkqvcgtPey

Q: 487   VHRDLKPDNLLITSLGHIKLTDFGLSKIGLMSMATNLYEGHIEKDTREFVDKQVCGTPEY  546

         ************************************************************

S: 181   iaPevilrqgygkpvdwwalgiilyeflvgivpffgdtpeelfaqvlsdeivwPekdeal  240

         iaPevi+rqgygkpvdwwa+g++lyeflvg+vpffgdtpeelf+qv+sdei+wPe+deal

Q: 547   IAPEVIFRQGYGKPVDWWAMGVVLYEFLVGCVPFFGDTPEELFGQVVSDEIMWPEGDEAL  606

         ************************************************************

S: 241   ssealelisellesnPrerlgtgsaaevkqhefl  274

         +++a++li++ll+++P +rlgtg+++evkqh+f+

Q: 607   PADAQDLITRLLRQSPLDRLGTGGTHEVKQHPFF  640

         ********************************97

Domain Sequence
(FASTA)

FETIKLISNG AYGAVYLVRH RDTRQRFAIK KINKQNLILR NQIQQVFVER DILTFAENPF 60

VVSMFCSFET RRHLCMVMEY VEGGDCATLL KNMGPLPVDM ARMYFAETVL ALEYLHNYGI 120

VHRDLKPDNL LITSLGHIKL TDFGLSKIGL MSMATNLYEG HIEKDTREFV DKQVCGTPEY 180

IAPEVIFRQG YGKPVDWWAM GVVLYEFLVG CVPFFGDTPE ELFGQVVSDE IMWPEGDEAL 240

PADAQDLITR LLRQSPLDRL GTGGTHEVKQ HPFF 274

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0000287	; F:magnesium ion binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR000961	; AGC-kinase_C.
IPR011009	; Kinase-like_dom.
IPR015022	; MA_Ser/Thr_Kinase_dom.
IPR023142	; MAST_pre-PK_dom.
IPR001478	; PDZ.
IPR000719	; Prot_kinase_cat_dom.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF08926	; DUF1908; 1.
PF00595	; PDZ; 1.
PF00069	; Pkinase; 1.

SMARTs

SM00228	; PDZ; 1.
SM00133	; S_TK_X; 1.
SM00220	; S_TKc; 1.

Prosites

PS51285	; AGC_KINASE_CTER; 1.
PS50106	; PDZ; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013