EKS-AIM-00159

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-AIM-00159

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/TTK	488.2	6.5E-147	525	791	267

Status

Unreviewed

Ensembl Protein

ENSAMEP00000013479

UniProt Accession

G1M2B8;

Protein Name

Protein Synonyms/Alias

Gene Name

TTK

Gene Synonyms/Alias

TTK;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSAMEG00000012771	ENSAMEP00000013479	ENSAMET00000014040

Organism

Ailuropoda melanoleuca

Functional Description

Protein Length

858

Protein Sequence
(FASTA)

MEAEDLSGRE LTIDSIMNKV RDIKNKFKNE DLTDELSLNK VSADTTDNSG TVNQIMMMAN 60

NPEDWLNLLL KLEKNSVPLN DALLNKLIGR YSQAIEALPP DKYGQNESFA QIQVRFAELK 120

AIQEPDDARD YFQMARANCK KFAFAHISFA QFELSQGNFK KSKQLLHKAV ECGAVPLEML 180

EIAIRNLNLQ KKQLLSEEEK KSLAASTVLT SQESFPSSLG HLQNRNISCD SRGQTTKARF 240

LYGENMPPQD SEIGHRNPLK QTNKAKRSCP FGRVPVNLLS SPDYGKTDGS VVPSFTKSNR 300

QTSGSELRDM IVPGSKSSGN DSSELRNFKS IQNIHSKEPL ISDEKSSELI TDSVTLKNKT 360

ESSLLTKLEE TKEHQEPKVP ESNQKQWQFV RKPECVNQNP AASSNQWQIP EISRKADTEQ 420

KQTTFEQPAF SVSRQSPPIS APKWIDPKSI CKTPSSSAMD DYMSCFRTPV VKNDFPPPCQ 480

LSTPYSQLAY FQQQQQQIPV TPLQTLQISA SSSTNECISV KGRMYSILKQ IGSGGSSKVF 540

QVLNEKKQIH AIKYVNLEEA DNQTIESYRN EIAYLNKLQQ HSDKIIRLYD YEITDQYIYM 600

VMECGNIDLN SWLKKKKSIN PWERKSYWKN MLEAVYTIHQ HGIVHSDLKP ANFLIVDGML 660

KLIDFGIANQ MQPDTTSIVK DSQVGTVNYM PPEAIKDMSS SRENGKSKSK ISPKSDVWSL 720

GCILYYMTYG KTPFQHIINQ ISKLHAIIDP NHEIEFPDIP EKDLQDVLKC CLIRDPKQRI 780

SIPELLEHPY VQIQTHPAGN QMAKGTTEEM KYVLGQLVGL NSPNSILKAA KTLYDHYSSG 840

ERHDSSSSKT FEKKWEKK 858

Nucleotide Sequence
(FASTA)

ATGGAGGCTG AGGATTTAAG TGGCAGAGAA TTGACAATTG ATTCTATAAT GAACAAAGTG 60

AGAGATATTA AAAATAAATT TAAAAATGAA GACCTTACTG ATGAGCTAAG CTTGAATAAA 120

GTCTCTGCTG ATACTACAGA TAACTCGGGA ACTGTTAACC AAATTATGAT GATGGCAAAC 180

AACCCAGAGG ACTGGTTGAA TTTGTTGCTC AAACTAGAGA AAAACAGTGT TCCCCTAAAT 240

GATGCTCTTT TAAATAAATT GATTGGTCGT TACAGTCAAG CAATTGAAGC CCTTCCTCCA 300

GATAAATATG GCCAAAATGA GAGTTTTGCT CAAATTCAAG TGAGATTTGC TGAATTAAAA 360

GCTATTCAGG AGCCAGATGA TGCCCGTGAC TACTTTCAGA TGGCCAGAGC AAACTGCAAG 420

AAATTTGCTT TTGCTCATAT ATCTTTTGCA CAGTTTGAAC TATCACAAGG TAATTTCAAA 480

AAAAGTAAAC AACTTCTTCA TAAAGCTGTA GAATGTGGAG CAGTGCCACT GGAAATGCTG 540

GAAATTGCCA TTCGGAATTT AAACCTTCAA AAGAAGCAGC TGCTTTCAGA AGAGGAAAAG 600

AAGAGTTTAG CAGCATCTAC AGTTTTGACG TCTCAAGAAT CATTCCCCAG TTCACTTGGA 660

CATTTACAAA ATAGGAACAT CAGTTGTGAT TCCAGAGGAC AGACTACAAA AGCCAGGTTT 720

TTGTACGGTG AGAACATGCC CCCTCAAGAT TCGGAGATAG GTCATCGAAA TCCCTTGAAA 780

CAAACAAACA AAGCTAAACG GTCATGCCCA TTTGGAAGAG TCCCAGTTAA CCTTCTAAGT 840

AGCCCGGACT ATGGGAAGAC AGATGGTTCA GTTGTACCAA GTTTTACAAA AAGTAATAGA 900

CAGACCTCTG GATCAGAACT CCGAGATATG ATTGTGCCTG GATCTAAATC AAGTGGAAAT 960

GATTCCAGTG AATTGAGAAA CTTTAAGTCT ATTCAAAATA TCCATTCCAA GGAACCTCTG 1020

ATCTCAGATG AGAAGAGTTC TGAACTTATT ACTGATTCAG TAACCCTGAA GAATAAAACT 1080

GAATCAAGTC TTCTAACAAA ATTAGAAGAA ACTAAGGAAC ATCAAGAACC AAAGGTTCCA 1140

GAGAGTAACC AGAAACAGTG GCAGTTTGTG AGAAAGCCAG AATGTGTAAA CCAGAATCCT 1200

GCTGCATCTT CAAATCAGTG GCAGATTCCA GAGATATCCC GAAAAGCTGA TACAGAGCAG 1260

AAACAAACCA CTTTTGAGCA ACCTGCCTTT TCAGTTTCAA GGCAGTCACC ACCAATATCA 1320

GCACCTAAGT GGATTGATCC AAAATCTATT TGTAAAACAC CCAGTAGCAG TGCCATGGAT 1380

GATTACATGA GCTGTTTTAG AACTCCAGTT GTAAAGAATG ACTTTCCACC TCCTTGTCAG 1440

TTGTCAACAC CTTATAGCCA ACTTGCCTAT TTCCAGCAGC AACAGCAGCA AATACCTGTT 1500

ACTCCACTTC AAACTTTACA GATTTCAGCA TCCTCCTCAA CAAATGAATG CATTTCGGTT 1560

AAAGGAAGAA TGTATTCTAT ATTGAAGCAG ATAGGAAGTG GAGGCTCAAG TAAGGTATTC 1620

CAGGTTTTGA ATGAAAAGAA ACAGATACAT GCCATAAAAT ATGTAAACTT GGAAGAAGCA 1680

GATAATCAAA CAATTGAGAG TTACCGGAAT GAAATTGCTT ACTTGAATAA ACTACAACAA 1740

CACAGTGATA AAATCATCCG ACTTTATGAT TATGAAATCA CGGACCAGTA CATTTACATG 1800

GTAATGGAGT GTGGAAATAT AGACCTAAAT AGTTGGCTTA AAAAGAAAAA ATCCATCAAT 1860

CCATGGGAAC GCAAAAGTTA CTGGAAAAAT ATGTTGGAGG CAGTTTACAC AATTCATCAA 1920

CATGGCATCG TTCACAGTGA TCTGAAACCT GCTAACTTTC TGATAGTTGA TGGAATGCTA 1980

AAGCTAATTG ACTTTGGGAT TGCAAACCAA ATGCAACCAG ATACAACAAG TATTGTTAAA 2040

GATTCTCAGG TTGGTACAGT TAATTATATG CCACCAGAAG CAATCAAAGA TATGTCTTCC 2100

TCAAGAGAGA ATGGGAAATC CAAGTCAAAG ATAAGCCCTA AAAGTGATGT TTGGTCCTTA 2160

GGATGCATTT TGTACTATAT GACTTATGGG AAGACACCAT TTCAGCATAT AATTAATCAG 2220

ATTTCTAAAT TACATGCCAT AATTGACCCT AATCATGAAA TTGAATTTCC AGATATTCCA 2280

GAGAAAGACC TTCAAGATGT GTTAAAGTGT TGTTTAATAA GGGACCCTAA ACAGAGGATA 2340

TCCATTCCTG AGCTCCTAGA GCATCCATAT GTTCAAATTC AAACTCATCC AGCAGGTAAC 2400

CAAATGGCTA AGGGCACCAC TGAAGAAATG AAATATGTTC TGGGCCAACT CGTTGGTCTG 2460

AATTCCCCTA ACTCCATTTT GAAAGCTGCT AAAACTTTAT ATGACCACTA TAGTAGTGGT 2520

GAAAGGCATG ATTCCTCTTC ATCCAAGACT TTTGAAAAAA AATGGGAGAA AAAATGA 2577

Domain Profile

S: 1     yeilkklGsGGsskvfkvksekkrvyalkvvdleaaddqtidgykneielleklqdqs.k  59

         y+ilk++GsGGsskvf+v++ekk+++a+k+v+le+ad+qti++y+nei++l+klq++s k

Q: 525   YSILKQIGSGGSSKVFQVLNEKKQIHAIKYVNLEEADNQTIESYRNEIAYLNKLQQHSdK  584

         99********************************************************9*

S: 60    virlydyeledsllylvmecGdidlnkilkkkksiepdyelvsyykemleavkvihqhGi  119

         +irlydye++d+++y+vmecG+idln++lkkkksi+p +e++sy+k+mleav +ihqhGi

Q: 585   IIRLYDYEITDQYIYMVMECGNIDLNSWLKKKKSINP-WERKSYWKNMLEAVYTIHQHGI  643

         *************************************.**********************

S: 120   vhsdlkPanfllvdGilklidfGianavaedttsivkesqvGtvnylaPealkdmsssqs  179

         vhsdlkPanfl+vdG+lklidfGian++++dttsivk+sqvGtvny++Pea+kdmsss

Q: 644   VHSDLKPANFLIVDGMLKLIDFGIANQMQPDTTSIVKDSQVGTVNYMPPEAIKDMSSS--  701

         **********************************************************..

S: 180   sereaekskikvsrksdvwslGcilylllygktPfgsirnqvskllaiinPdveiefPei  239

           re++ksk+k+s+ksdvwslGcily+++ygktPf++i+nq+skl+aii+P++eiefP+i

Q: 702   --RENGKSKSKISPKSDVWSLGCILYYMTYGKTPFQHIINQISKLHAIIDPNHEIEFPDI  759

         ..**********************************************************

S: 240   tsniekslvellkaclkrnPkkrisvdellsspfv  274

         +   ek+l+++lk+cl r+Pk+ris++ell++p+v

Q: 760   P---EKDLQDVLKCCLIRDPKQRISIPELLEHPYV  791

         *...*****************************96

Domain Sequence
(FASTA)

YSILKQIGSG GSSKVFQVLN EKKQIHAIKY VNLEEADNQT IESYRNEIAY LNKLQQHSDK 60

IIRLYDYEIT DQYIYMVMEC GNIDLNSWLK KKKSINPWER KSYWKNMLEA VYTIHQHGIV 120

HSDLKPANFL IVDGMLKLID FGIANQMQPD TTSIVKDSQV GTVNYMPPEA IKDMSSSREN 180

GKSKSKISPK SDVWSLGCIL YYMTYGKTPF QHIINQISKL HAIIDPNHEI EFPDIPEKDL 240

QDVLKCCLIR DPKQRISIPE LLEHPYV 267

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.
IPR011990	; TPR-like_helical.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013