EKS-AIM-00055

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-AIM-00055

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDK	387.7	2.9E-116	240	521	282

Status

Unreviewed

Ensembl Protein

ENSAMEP00000013840

UniProt Accession

G1M3C8;

Protein Name

Protein Synonyms/Alias

Gene Name

CDK16

Gene Synonyms/Alias

CDK16;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSAMEG00000013109	ENSAMEP00000013840	ENSAMET00000014417

Organism

Ailuropoda melanoleuca

Functional Description

Protein Length

571

Protein Sequence
(FASTA)

MTFYGRAQGR IGGPSSVLGE PLAPPTAGPI TTAAPKNACC GGLCSHSEAA PIEANSPPVG 60

PLPSASHPGL NTQVAMDRMK KIKRQLSMTL RGGRGVDKTN GAPEQIGLDE SGGGGGSDLG 120

EVPTRAAPGE PRSGRGPLSS APEIVHEDLK MGSDGESDQA SATSSDEVQS PVRVRMRNHP 180

PRKISTEDIN KRLSLPADIR LPEGYLEKLT LNSPIFDKPL SRRLRRVSLS EIGFGKLETY 240

IKLDKLGEGT YATVYKGKSK LTDNLVALKE IRLEHEEGAP CTAIREVSLL KDLKHANIVT 300

LHDIIHTEKS LTLVFEYLDK DLKQYLDDCG NVINMHNVKL FLFQLLRGLA YCHRQKVLHR 360

DLKPQNLLIN ERGELKLADF GLARAKSIPT KTYSNEVVTL WYRPPDILLG STDYSTQIDM 420

WGVGCIFYEM ATGRPLFPGS TVEEQLHFIF RILGTPTEET WPGILSNEEF KTYNYPKYRA 480

EALLSHAPRL DSDGADLLTK LLQFEGRNRI SAEDAMKHPF FLSLGDRIHK LPDTTSIFAL 540

KEIQLQKEAS LRSSSMPDSG RPAFRVVDTE F 571

Nucleotide Sequence
(FASTA)

ATGACATTCT ATGGGCGAGC CCAGGGCCGT ATTGGCGGCC CCTCCTCAGT CCTGGGCGAG 60

CCCCTCGCCC CACCCACAGC TGGGCCCATC ACCACCGCCG CACCTAAGAA CGCCTGCTGT 120

GGAGGCCTTT GTTCCCACAG TGAAGCTGCC CCCATAGAGG CCAACAGTCC ACCAGTTGGG 180

CCTTTGCCCT CAGCCAGCCA CCCAGGCCTC AACACCCAGG TCGCCATGGA TCGGATGAAG 240

AAGATCAAGC GGCAGCTGTC GATGACACTC CGAGGGGGCC GAGGTGTGGA CAAGACCAAT 300

GGTGCCCCTG AGCAGATAGG CCTGGATGAG AGTGGGGGTG GCGGTGGCAG TGACCTTGGA 360

GAGGTACCCA CTCGTGCCGC TCCTGGGGAA CCTCGCTCTG GACGGGGCCC ACTCAGCTCT 420

GCACCAGAGA TTGTACATGA GGACTTGAAG ATGGGGTCTG ATGGGGAAAG TGACCAGGCT 480

TCAGCCACGT CCTCGGATGA GGTGCAGTCG CCAGTGAGGG TGCGCATGCG CAACCATCCC 540

CCACGCAAGA TCTCCACTGA GGACATCAAC AAGCGCCTGT CACTACCAGC CGACATCCGG 600

CTGCCTGAGG GCTACCTTGA GAAGCTGACC CTCAATAGCC CCATCTTCGA CAAGCCCCTC 660

AGCCGCCGCC TCCGCCGTGT CAGCCTGTCT GAGATTGGTT TTGGGAAACT GGAGACCTAC 720

ATCAAGCTGG ACAAGCTGGG TGAGGGTACC TATGCCACCG TCTACAAAGG CAAAAGCAAG 780

CTCACAGACA ACCTTGTGGC ACTCAAGGAG ATCAGACTGG AACACGAAGA GGGGGCACCC 840

TGCACCGCCA TCCGGGAAGT GTCCCTGCTC AAGGACCTCA AACATGCCAA CATCGTCACA 900

CTACATGACA TCATCCACAC GGAGAAGTCC CTCACCCTTG TCTTTGAGTA CCTGGACAAG 960

GACCTGAAAC AGTACCTGGA TGACTGTGGG AACGTCATCA ACATGCACAA CGTGAAACTC 1020

TTCCTGTTCC AGCTGCTCCG TGGCCTGGCC TACTGCCACC GGCAGAAGGT GCTACACCGA 1080

GACCTCAAAC CCCAAAACCT GCTCATCAAC GAGAGAGGAG AGCTGAAGCT GGCAGACTTC 1140

GGCCTGGCCC GAGCTAAGTC AATTCCAACG AAGACCTACT CCAATGAGGT GGTGACACTG 1200

TGGTACCGGC CCCCCGACAT TCTGCTTGGG TCCACGGACT ACTCTACCCA GATTGACATG 1260

TGGGGTGTGG GCTGCATCTT CTATGAGATG GCCACAGGCC GGCCCCTCTT CCCAGGCTCC 1320

ACAGTGGAGG AACAGCTGCA CTTCATCTTC CGCATCTTGG GAACCCCAAC TGAGGAGACG 1380

TGGCCAGGCA TTCTGTCCAA CGAAGAGTTC AAGACATACA ACTACCCCAA GTATCGAGCC 1440

GAGGCCCTTT TGAGCCATGC ACCCCGACTT GACAGCGATG GGGCTGACCT CCTCACCAAG 1500

CTGCTGCAGT TTGAAGGTCG CAATCGGATC TCCGCAGAGG ACGCCATGAA ACATCCATTC 1560

TTCCTCAGTC TGGGGGATCG GATCCATAAA CTTCCTGACA CTACTTCCAT ATTTGCACTA 1620

AAGGAGATCC AGCTGCAAAA GGAGGCCAGC CTTCGGTCTT CATCAATGCC TGACTCAGGC 1680

AGGCCAGCTT TCCGCGTGGT GGACACCGAG TTCTAA 1716

Domain Profile

S: 1     yeklekigeGtygkvykakdketgevvAlKkirlekekegvpitalrEisllkelkhkni  60

         y kl+k+geGty++vyk+k+k t+++vAlK+irle+e eg p+ta+rE+sllk+lkh+ni

Q: 240   YIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRLEHE-EGAPCTAIREVSLLKDLKHANI  298

         7799********************************9.9*********************

S: 61    vkLlevvakdkkklyLvfefleqdLkkllkkkkkkklsleevkslllqlleglaylHsnk  120

         v+L+++++ ++k+l+Lvfe+l++dLk++l+++ +  +++++vk +l+qll+glay+H++k

Q: 299   VTLHDIIH-TEKSLTLVFEYLDKDLKQYLDDCGN-VINMHNVKLFLFQLLRGLAYCHRQK  356

         ********.99***********************.*************************

S: 121   ilHRDlKpqNlLiskegklklaDfGlarafssplktytkevvTlwYraPelLlgakeYst  180

         +lHRDlKpqNlLi+++g+lklaDfGlara s p+kty++evvTlwYr+P++Llg+++Yst

Q: 357   VLHRDLKPQNLLINERGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYST  416

         ************************************************************

S: 181   avDiWsvgcilaelltrkplfqgkseidqlerifkllgtpsekvwpevsklpeyk.ksfp  239

         ++D+W+vgci+ e++t +plf+g++  +ql+ if++lgtp+e++wp++ + +e+k +++p

Q: 417   QIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFKtYNYP  476

         *******************************************************88***

S: 240   kkkkkklkekvkklkekaldllekllaldpkkRisakealqhkyf  284

         k++++ l ++ ++l++++ dll+kll+++ ++Risa++a++h++f

Q: 477   KYRAEALLSHAPRLDSDGADLLTKLLQFEGRNRISAEDAMKHPFF  521

         *******************************************98

Domain Sequence
(FASTA)

YIKLDKLGEG TYATVYKGKS KLTDNLVALK EIRLEHEEGA PCTAIREVSL LKDLKHANIV 60

TLHDIIHTEK SLTLVFEYLD KDLKQYLDDC GNVINMHNVK LFLFQLLRGL AYCHRQKVLH 120

RDLKPQNLLI NERGELKLAD FGLARAKSIP TKTYSNEVVT LWYRPPDILL GSTDYSTQID 180

MWGVGCIFYE MATGRPLFPG STVEEQLHFI FRILGTPTEE TWPGILSNEE FKTYNYPKYR 240

AEALLSHAPR LDSDGADLLT KLLQFEGRNR ISAEDAMKHP FF 282

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

aml:100482500

;

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013