EKS-AIM-00065

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-AIM-00065

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDK	353.0	1.1E-105	105	389	285

Status

Unreviewed

Ensembl Protein

ENSAMEP00000013960

UniProt Accession

G1M3P7;

Protein Name

Protein Synonyms/Alias

Gene Name

CDK15

Gene Synonyms/Alias

CDK15;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSAMEG00000013241	ENSAMEP00000013960	ENSAMET00000014541

Organism

Ailuropoda melanoleuca

Functional Description

Protein Length

437

Protein Sequence
(FASTA)

MGQELCSKTL QPGRSCHRCW EGGEAQSCQR TAPVPETPEP AIELTDLKEA SCSMTSFHPR 60

GLQAVRAGKF KSKRPRSNSD SFKEEDVRQG FQWRKSLPFG AASSYLNLEK LGEGSYATVY 120

KGISRINGQL VALKVISMNA EEGVPFTAIR EASLLKGLKH ANIVLLHDII HTKETLTFVF 180

EYMHTDLAQY MSQHPGGLRP HNVRLFMFQL LRGLAYIHHQ HVLHRDLKPQ NLLISHLGEL 240

KLADFGLARA KSIPSQTYSS EVVTLWYRPP DALLGATEYS SELDIWGAGC IFIEMFQGQP 300

LFPGVSNILE QLEKIWEVLG VPTEDTWPGV SKLPNYNPEW FPLPKPRSLQ NVWNRLGRAP 360

EAEDLASQML RGFPRDRVSA QEALVHDYFS ALPSQLHQLP NEESLFTVSG VRLKPEMCDL 420

LVSYRQGHHP AQFSKCW 437

Nucleotide Sequence
(FASTA)

ATGGGTCAAG AGCTGTGTTC AAAGACTCTC CAGCCTGGAC GCAGCTGCCA TCGCTGCTGG 60

GAGGGAGGCG AGGCACAGAG CTGCCAGAGA ACAGCGCCTG TGCCCGAGAC GCCGGAGCCT 120

GCGATCGAGC TGACGGACCT AAAAGAAGCG TCATGTTCCA TGACTTCATT TCACCCCAGG 180

GGACTTCAGG CTGTCCGTGC CGGGAAGTTC AAGAGTAAAA GGCCACGGAG TAACAGTGAT 240

TCTTTTAAGG AAGAGGATGT GAGGCAGGGT TTTCAGTGGA GGAAGAGCCT CCCTTTTGGG 300

GCAGCCTCAT CTTACTTGAA CTTGGAGAAG CTGGGTGAAG GTTCTTATGC TACAGTTTAC 360

AAGGGGATTA GCAGGATAAA TGGACAACTA GTGGCTCTTA AAGTCATCAG CATGAATGCA 420

GAGGAAGGAG TCCCATTTAC AGCTATTCGG GAAGCTTCTC TCTTGAAGGG TTTGAAACAT 480

GCCAATATTG TGCTCCTGCA TGACATAATC CACACCAAAG AGACTCTGAC ATTCGTTTTT 540

GAATACATGC ACACAGACCT GGCCCAGTAC ATGTCTCAGC ACCCAGGAGG GCTTCGTCCG 600

CACAATGTCA GGCTTTTCAT GTTTCAACTT TTGCGGGGCC TGGCGTACAT CCACCACCAA 660

CACGTTCTTC ACAGGGACCT GAAACCTCAG AACTTACTCA TCAGTCACCT GGGAGAGCTC 720

AAACTGGCTG ATTTTGGTCT CGCTCGGGCA AAGTCCATTC CCAGCCAGAC ATACTCTTCA 780

GAAGTTGTGA CCCTCTGGTA CCGGCCACCT GATGCCTTGC TGGGAGCCAC TGAATATTCC 840

TCTGAACTGG ACATATGGGG TGCAGGCTGC ATCTTTATTG AAATGTTCCA GGGTCAACCT 900

TTGTTTCCTG GGGTTTCCAA CATCCTTGAA CAGCTGGAGA AGATCTGGGA GGTGTTGGGA 960

GTCCCTACAG AGGATACCTG GCCTGGAGTT TCTAAGCTAC CTAACTACAA TCCAGAATGG 1020

TTCCCACTGC CTAAGCCTCG AAGCCTTCAA AATGTCTGGA ACAGGTTGGG CCGGGCTCCC 1080

GAGGCTGAAG ACCTGGCCTC CCAAATGCTG AGAGGCTTTC CTAGAGACCG CGTCTCCGCC 1140

CAGGAGGCCC TGGTTCATGA CTATTTCAGT GCCCTGCCAT CTCAGCTGCA CCAGCTTCCC 1200

AACGAGGAGT CTTTGTTCAC AGTTTCGGGA GTGAGGCTAA AGCCAGAAAT GTGTGACCTT 1260

TTGGTCTCTT ACCGGCAAGG TCACCACCCA GCCCAGTTTA GCAAATGCTG GTGA 1314

Domain Profile

S: 1     yeklekigeGtygkvykakdketgevvAlKkirlekekegvpitalrEisllkelkhkni  60

         y +lek+geG+y++vyk+ ++ +g++vAlK i ++ e egvp+ta+rE sllk lkh+ni

Q: 105   YLNLEKLGEGSYATVYKGISRINGQLVALKVISMNAE-EGVPFTAIREASLLKGLKHANI  163

         6789******************************998.9*********************

S: 61    vkLlevvakdkkklyLvfefleqdLkkllkkkkkkklsleevkslllqlleglaylHsnk  120

         v L+++++ +k++l++vfe++++dL++++++++  +l++++v+ +++qll+glay+H+++

Q: 164   VLLHDIIH-TKETLTFVFEYMHTDLAQYMSQHPG-GLRPHNVRLFMFQLLRGLAYIHHQH  221

         ********.99***********************.*************************

S: 121   ilHRDlKpqNlLiskegklklaDfGlarafssplktytkevvTlwYraPelLlgakeYst  180

         +lHRDlKpqNlLis+ g+lklaDfGlara s p++ty++evvTlwYr+P+ Llga+eYs+

Q: 222   VLHRDLKPQNLLISHLGELKLADFGLARAKSIPSQTYSSEVVTLWYRPPDALLGATEYSS  281

         ************************************************************

S: 181   avDiWsvgcilaelltrkplfqgkse.idqlerifkllgtpsekvwpevsklpeyk.ksf  238

         ++DiW++gci+ e+++ +plf+g s+  +qle+i+++lg p+e++wp+vsklp+y+ + f

Q: 282   ELDIWGAGCIFIEMFQGQPLFPGVSNiLEQLEKIWEVLGVPTEDTWPGVSKLPNYNpEWF  341

         ***********************99967****************************8889

S: 239   pkkkkkklkekvkklk..ekaldllekllaldpkkRisakealqhkyf  284

         p  k+++l++++++l    +a dl +++l+  p++R+sa+eal h+yf

Q: 342   PLPKPRSLQNVWNRLGraPEAEDLASQMLRGFPRDRVSAQEALVHDYF  389

         999999*******99954569**************************9

Domain Sequence
(FASTA)

YLNLEKLGEG SYATVYKGIS RINGQLVALK VISMNAEEGV PFTAIREASL LKGLKHANIV 60

LLHDIIHTKE TLTFVFEYMH TDLAQYMSQH PGGLRPHNVR LFMFQLLRGL AYIHHQHVLH 120

RDLKPQNLLI SHLGELKLAD FGLARAKSIP SQTYSSEVVT LWYRPPDALL GATEYSSELD 180

IWGAGCIFIE MFQGQPLFPG VSNILEQLEK IWEVLGVPTE DTWPGVSKLP NYNPEWFPLP 240

KPRSLQNVWN RLGRAPEAED LASQMLRGFP RDRVSAQEAL VHDYF 285

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

aml:100481670

;

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013