EKS-AIM-00360

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-AIM-00360

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
STE/STE11	366.6	9.0E-110	372	632	261

Status

Unreviewed

Ensembl Protein

ENSAMEP00000017777

UniProt Accession

G1MEJ9;

Protein Name

Protein Synonyms/Alias

Gene Name

MAP3K2

Gene Synonyms/Alias

MAP3K2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSAMEG00000016823	ENSAMEP00000017777	ENSAMET00000018501

Organism

Ailuropoda melanoleuca

Functional Description

Protein Length

634

Protein Sequence
(FASTA)

LDDQQALNSI MQDLAVLHKA SRPAFLYRKP EKQNLHHQKI QNDVRVKFEH RGEKRILQFP 60

RPVKLEDLRS KAKIAFGQSM DLHYTNNELV IPLTTQDDLD KAVELLDRSI HMKSLKILLV 120

INGSTQVRIE TSFSEDYRIY PSEKPLPSLE DLDNTVFGAE RKKRLSIIGP TSRDRSSPPP 180

GYIPDELHQV ARNGSFTSIN SEGEFIPESM DQLKMLDPLS LSSPENSGSG SCPSLDSPLD 240

GESYPKSRMP RAQSYPDNHQ EFSVDYDNPI FEKFGKGGTY PRRYHVSYHH QDYNDGRKTF 300

PRARRTQGTS FRSPVSFSPT DHSLSTSSGS SIFTPEYDDS RIRRRGSDID NPTLTVMDIS 360

PPSRSPRAPT NWRLGKLLGQ GAFGRVYLCY DVDTGRELAV KQVQFDPDSP ETSKEVNALE 420

CEIQLLKNLL HERIVQYYGC LRDPQEKTLS IFMEYMPGGS IKDQLKAYGA LTENVTRKYT 480

RQILEGVHYL HSNMIVHRDI KGANILRDST GNVKLGDFGA SKRLQTICLS GTGMKSVTGT 540

PYWMSPEVIS GEGYGRKADI WSVGCTVVEM LTEKPPWAEF EAMAAIFKIA TQPTNPKLPP 600

HVSDYTRDFL KRIFIEAKLR PSADELLRHM FVHY 634

Nucleotide Sequence
(FASTA)

TTAGATGATC AGCAGGCTTT GAACTCAATC ATGCAAGATT TGGCTGTTCT TCATAAAGCC 60

AGTCGACCAG CGTTTCTTTA CAGGAAACCA GAAAAACAAA ATCTTCATCA CCAAAAAATA 120

CAGAATGATG TTCGAGTCAA ATTTGAACAT AGAGGGGAAA AAAGAATCCT TCAGTTCCCC 180

AGACCAGTTA AACTGGAAGA TCTGAGATCT AAGGCTAAAA TTGCCTTTGG ACAGTCTATG 240

GATCTCCATT ATACCAATAA TGAGTTGGTA ATTCCATTAA CTACCCAAGA TGACTTGGAC 300

AAAGCTGTGG AACTGCTGGA TCGTAGTATT CACATGAAGA GCCTCAAGAT ATTACTTGTA 360

ATAAATGGAA GTACACAGGT ACGAATTGAG ACTTCTTTCA GTGAGGATTA TAGGATTTAT 420

CCCAGTGAAA AACCATTGCC ATCACTAGAA GATTTGGATA ACACAGTATT TGGAGCAGAG 480

AGGAAAAAGC GGCTTTCCAT AATAGGTCCC ACTAGTAGAG ATAGAAGCTC CCCTCCCCCA 540

GGATACATTC CAGATGAATT ACACCAGGTT GCCCGGAATG GGTCATTCAC CAGTATCAAC 600

AGTGAAGGAG AGTTCATTCC AGAGAGCATG GACCAATTAA AGATGCTGGA CCCATTGTCT 660

TTAAGTAGCC CTGAAAATTC TGGCTCAGGA AGTTGTCCAT CACTTGATAG TCCTTTGGAT 720

GGAGAGAGCT ATCCAAAATC ACGAATGCCT AGGGCACAGA GCTACCCAGA TAATCATCAG 780

GAATTTTCAG TAGACTATGA TAACCCTATA TTTGAGAAAT TTGGAAAAGG AGGAACATAC 840

CCAAGAAGGT ATCATGTTTC ATATCACCAT CAAGACTATA ATGATGGTCG TAAAACTTTT 900

CCAAGAGCTA GAAGAACCCA GGGAACCAGC TTCCGGTCTC CTGTTAGTTT CAGTCCTACT 960

GATCATTCTT TAAGCACTAG CAGTGGAAGC AGTATCTTTA CCCCAGAGTA TGATGATAGT 1020

CGAATCAGAA GAAGGGGAAG TGACATAGAC AATCCTACTT TGACTGTAAT GGACATCAGC 1080

CCACCCAGCC GCTCACCTCG TGCTCCAACC AACTGGAGAT TGGGCAAACT GCTTGGCCAG 1140

GGAGCATTTG GCAGGGTCTA CCTCTGTTAT GATGTCGATA CAGGAAGAGA ATTGGCAGTT 1200

AAACAAGTTC AGTTTGACCC TGATAGCCCT GAGACCAGCA AGGAAGTAAA TGCACTTGAG 1260

TGTGAAATTC AGTTGTTGAA AAACTTGCTG CATGAGCGAA TCGTTCAGTA TTATGGCTGT 1320

TTGAGGGATC CCCAGGAAAA AACACTTTCC ATTTTTATGG AATATATGCC AGGGGGTTCA 1380

ATTAAGGACC AATTAAAAGC ATACGGAGCC CTTACTGAGA ACGTGACTAG GAAATACACC 1440

CGTCAGATTC TGGAGGGGGT ACATTATTTG CACAGTAATA TGATTGTTCA TAGAGATATC 1500

AAAGGTGCAA ATATTCTGCG GGATTCAACA GGCAACGTCA AACTGGGAGA TTTTGGGGCC 1560

AGCAAACGGC TTCAGACCAT CTGTCTTTCA GGGACAGGGA TGAAGTCTGT CACAGGCACA 1620

CCATACTGGA TGAGCCCCGA AGTAATTAGT GGAGAAGGCT ATGGCAGAAA AGCAGATATC 1680

TGGAGTGTGG GTTGTACTGT GGTGGAAATG CTAACTGAAA AGCCTCCTTG GGCGGAATTT 1740

GAAGCTATGG CTGCCATCTT TAAAATCGCC ACTCAGCCAA CAAACCCAAA GCTGCCACCT 1800

CATGTCTCAG ACTATACTCG AGATTTCCTC AAACGGATCT TTATAGAGGC CAAACTGAGA 1860

CCTTCAGCTG ATGAACTGTT AAGGCACATG TTTGTGCATT AT 1902

Domain Profile

S: 1     wqkrevigkGsfgsvyaaldvdtgellavKeveikpekksekkevkalkeEikllkelkH  60

         w+ ++++g+G+fg+vy+++dvdtg+ lavK+v+++p++ +++kev+al++Ei+llk+l H

Q: 372   WRLGKLLGQGAFGRVYLCYDVDTGRELAVKQVQFDPDSPETSKEVNALECEIQLLKNLLH  431

         78899*******************************************************

S: 61    enivkyyGv..eveeeelkiflEyvegGslssllekygkleesvikkytkqileglayLH  118

         e+iv+yyG+  + +e++l+if+Ey++gGs++++l++yg+l+e+v++kyt+qileg++yLH

Q: 432   ERIVQYYGClrDPQEKTLSIFMEYMPGGSIKDQLKAYGALTENVTRKYTRQILEGVHYLH  491

         *********777899*********************************************

S: 119   ekkivHRDiKgaNilldssgvvklsDFGaskrlaelntkaaelesltGtlaymaPEvikk  178

         +++ivHRDiKgaNil ds+g+vkl+DFGaskrl++++ + + ++s+tGt+++m+PEvi++

Q: 492   SNMIVHRDIKGANILRDSTGNVKLGDFGASKRLQTICLSGTGMKSVTGTPYWMSPEVISG  551

         **********************************************************99

S: 179   kekgygrkaDiWslgcvviemltgkrPfaeldeelaimfkvgakktkPeipeklseegkd  238

         +  gygrkaDiWs+gc+v+emlt+k+P+ae+ e++a++fk++++ t+P++p ++s+ ++d

Q: 552   E--GYGRKADIWSVGCTVVEMLTEKPPWAEF-EAMAAIFKIATQPTNPKLPPHVSDYTRD  608

         8..****************************.9***************************

S: 239   flekcleldpkkrpsaeeLLkhefl  263

         fl++++ +++k rpsa+eLL+h+f+

Q: 609   FLKRIF-IEAKLRPSADELLRHMFV  632

         ******.899*************96

Domain Sequence
(FASTA)

WRLGKLLGQG AFGRVYLCYD VDTGRELAVK QVQFDPDSPE TSKEVNALEC EIQLLKNLLH 60

ERIVQYYGCL RDPQEKTLSI FMEYMPGGSI KDQLKAYGAL TENVTRKYTR QILEGVHYLH 120

SNMIVHRDIK GANILRDSTG NVKLGDFGAS KRLQTICLSG TGMKSVTGTP YWMSPEVISG 180

EGYGRKADIW SVGCTVVEML TEKPPWAEFE AMAAIFKIAT QPTNPKLPPH VSDYTRDFLK 240

RIFIEAKLRP SADELLRHMF V 261

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Bos taurus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004672	; F:protein kinase activity
GO:0071260	; P:cellular response to mechanical stimulus
GO:0045893	; P:positive regulation of transcription, DNA-dependent

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000270	; OPR_PB1.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.

Pfam

PF00564	; PB1; 1.
PF00069	; Pkinase; 1.

SMARTs

SM00666	; PB1; 1.
SM00220	; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.

Prints

Created Date

20-Feb-2013