EPS-AIM-00018

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-AIM-00018

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
DSP/aDSP	69.8	2.3E-19	87	200	114

Status

Unreviewed

Ensembl Protein

ENSAMEP00000018385

UniProt Accession

D2HH76;

Protein Name

Protein Synonyms/Alias

Gene Name

DUSP11

Gene Synonyms/Alias

DUSP11; PANDA_010433;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSAMEG00000017403	ENSAMEP00000018385	ENSAMET00000019126

Organism

Ailuropoda melanoleuca

Functional Description

Protein Length

332

Protein Sequence
(FASTA)

MSQWHHARGG WGQGRAFSGR SSGKKKRGNH VPERWKDYLP VGQRMPGTRF IAFKVPLKKS 60

FEKNLAPEER FSPLDLFNKI QKQNQELGLI IDLTYTHRYY KPEDLPETIP YLKIYTIGHQ 120

VPDDDTIFKF KCAVNEFLKE NTDNDKLIGV HCTHGLNRTG YLICRYLIDV QGMRPDDAIE 180

LFNRCRGHCL ERQNYIEDLQ KGPIRKNWDS SVSRSSGFED ATHMMEPVHT TIKSVNQGHW 240

YNLHQTQGYP VPSWHFHSQT QDLQQSVRTF SQNQNVYQRG HIPPPCPPGE DYSQRRYSWN 300

VKPNASQAAQ NTVWYPGSYY RLSYPTYCGW TE 332

Nucleotide Sequence
(FASTA)

ATGAGCCAGT GGCATCATGC CCGCGGCGGC TGGGGCCAGG GACGCGCGTT CTCTGGACGT 60

AGCTCAGGCA AGAAGAAGCG CGGAAACCAT GTCCCGGAAA GGTGGAAAGA CTACCTCCCA 120

GTTGGACAAC GGATGCCTGG GACTCGTTTC ATTGCTTTCA AAGTTCCTTT GAAAAAGAGT 180

TTTGAAAAGA ACCTTGCTCC AGAAGAACGT TTTTCACCCT TGGATCTTTT TAACAAAATC 240

CAAAAACAGA ATCAAGAACT TGGACTAATT ATTGATTTAA CTTATACTCA CCGCTATTAT 300

AAACCAGAGG ACTTACCAGA AACGATTCCT TACTTAAAAA TTTATACAAT TGGGCATCAG 360

GTGCCTGACG ATGACACTAT TTTTAAATTC AAATGTGCTG TTAATGAGTT TTTAAAAGAA 420

AATACAGATA ATGACAAACT TATTGGTGTT CACTGTACCC ATGGCTTAAA CAGGACTGGC 480

TATCTCATCT GCAGATATTT AATTGATGTA CAAGGCATGA GGCCAGATGA TGCAATTGAA 540

TTATTCAATA GATGCCGCGG ACATTGCTTG GAAAGACAAA ACTACATTGA AGACCTTCAG 600

AAAGGTCCCA TCAGAAAGAA TTGGGATTCC AGTGTATCCA GATCAAGTGG TTTTGAAGAT 660

GCAACACATA TGATGGAACC AGTCCACACC ACTATTAAGT CTGTTAACCA AGGACATTGG 720

TATAACCTAC ATCAGACCCA AGGTTACCCA GTACCTTCTT GGCATTTCCA CAGCCAAACC 780

CAGGATTTGC AGCAGTCAGT AAGAACATTT TCACAGAACC AGAATGTTTA CCAGAGAGGC 840

CATATCCCTC CTCCTTGTCC CCCTGGAGAG GACTATTCAC AAAGGAGGTA CTCCTGGAAT 900

GTGAAGCCAA ACGCCAGTCA AGCAGCCCAG AATACAGTGT GGTATCCTGG CAGTTACTAC 960

AGACTGTCCT ATCCAACCTA TTGTGGATGG ACCGAATGA 999

Domain Profile

S: 26    lgitvvinaslsvikvqviPeylikkgityknipvdDsdvtdllqyfdeaaefideakek  85

         lg+ + ++ ++   k +  Pe +   +i   + +v D+d   ++++  +++ef++e++++

Q: 87    LGLIIDLTYTHRYYKPEDLPETIPYLKIYTIGHQVPDDD--TIFKFKCAVNEFLKENTDN  144

         466666777777788777888777666666666666665..59*****************

S: 86    ggkvlvHCaaGvsRSatlvlaYLmkveglslsdAieavkrkrpsiepnegfleQLl  141

         ++ + vHC++G++R+++l++ YL++v+g++ +dAie ++r+r+++ ++++++e L

Q: 145   DKLIGVHCTHGLNRTGYLICRYLIDVQGMRPDDAIELFNRCRGHCLERQNYIEDLQ  200

         *****************************************************986

Domain Sequence
(FASTA)

LGLIIDLTYT HRYYKPEDLP ETIPYLKIYT IGHQVPDDDT IFKFKCAVNE FLKENTDNDK 60

LIGVHCTHGL NRTGYLICRY LIDVQGMRPD DAIELFNRCR GHCLERQNYI EDLQ 114

Keyword

Complete proteome; Hydrolase; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Taeniopygia guttata"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0004725	; F:protein tyrosine phosphatase activity
GO:0008138	; F:protein tyrosine/serine/threonine phosphatase activity
GO:0035335	; P:peptidyl-tyrosine dephosphorylation

KEGG

InterPros

IPR000340	; Dual-sp_phosphatase_cat-dom.
IPR000387	; Tyr/Dual-specificity_Pase.
IPR016130	; Tyr_Pase_AS.

Pfam

PF00782

; DSPc; 1.

SMARTs

Prosites

PS00383	; TYR_PHOSPHATASE_1; 1.
PS50056	; TYR_PHOSPHATASE_2; 1.

Prints

Created Date

20-Feb-2013