EKS-AIM-00195

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-AIM-00195

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDKL	479.3	3.0E-144	4	286	283

Status

Unreviewed

Ensembl Protein

ENSAMEP00000018828

UniProt Accession

G1MHJ3;

Protein Name

Protein Synonyms/Alias

Gene Name

CDKL3

Gene Synonyms/Alias

CDKL3;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSAMEG00000017820	ENSAMEP00000018831	ENSAMET00000019584
ENSAMEG00000017820	ENSAMEP00000018828	ENSAMET00000019581

Organism

Ailuropoda melanoleuca

Functional Description

Protein Length

591

Protein Sequence
(FASTA)

MEMYETLGKV GEGSYGTVMK CKHKDTGQIV AIKIFYEKPE KSVNKIATRE IKFLKQFHHE 60

NLVNLIEVFR QKKKIHLVFE FVDHTVLDEL QHYCHGLESK RLRRYLFQIL RAIEYLHNNN 120

IIHRDIKPEN ILVSQSGITK LCDFGFARTL AAPGGIYTDY VATRWYRAPE LVLKDTSYGK 180

PVDIWALGCM IIEMATGNPY LPSSSDLDLL HKIVLKVGNL TPHLQNIFSK SPIFAGVVLP 240

QVQHPKNARK KYPKLNGLLA DIVDACLQID PAQRTSSTDL LHHEYFTRDG FIEKFIPELR 300

AKLLQEAKVN SFIKPKENSK ENELTKDERK TSYINTLLKP KENSKEMEKE KKPKEIKVRV 360

IKVKGGTGDI SEPNKIECEG GHYQQDAIEN AHTMSQDTKP VINEPPKPVN STNSNGMKDD 420

PRAGGSMMMP PINLTSNNLM ASNPNSNFSH PSSRLTERAR KRHTSSQSTR QVLSNSRQED 480

AGPTQSQMEK SVFNERTGQS DQMANGNKRK LNFSRSDRKE FHFPELPFTV QPKEVKGMEV 540

KQIKVLKRES KKTDSSKIPT LLNVDQNQEK QEGGGGHFKG KNLKRNRFFF W 591

Nucleotide Sequence
(FASTA)

ATGGAGATGT ATGAAACCCT CGGAAAAGTG GGAGAAGGAA GTTATGGAAC AGTGATGAAG 60

TGTAAACATA AGGATACTGG GCAGATAGTG GCCATTAAGA TATTTTATGA GAAACCAGAA 120

AAGTCTGTCA ACAAAATTGC AACGAGAGAA ATAAAGTTTT TAAAGCAATT TCATCATGAA 180

AACCTGGTCA ATCTGATTGA AGTTTTTAGG CAGAAAAAGA AAATTCACTT GGTATTTGAA 240

TTTGTTGACC ACACAGTATT AGATGAGTTA CAACATTATT GTCATGGACT AGAGAGTAAA 300

CGACTTAGAA GATACCTCTT CCAGATCCTT CGAGCAATTG AATATCTTCA CAATAATAAC 360

ATCATTCATC GAGATATAAA ACCTGAGAAT ATTTTAGTAT CCCAGTCAGG AATTACTAAG 420

CTCTGTGATT TTGGTTTTGC ACGAACTCTA GCAGCTCCTG GGGGCATTTA TACGGACTAT 480

GTGGCCACAC GCTGGTATAG AGCTCCAGAA TTAGTATTAA AAGATACCTC TTATGGAAAG 540

CCTGTAGATA TCTGGGCTTT GGGTTGTATG ATCATTGAGA TGGCTACTGG AAATCCCTAT 600

CTTCCTAGCA GTTCTGATTT GGATTTACTT CATAAAATTG TTTTAAAAGT AGGCAATTTG 660

ACACCTCACT TACAGAATAT CTTTTCCAAG AGTCCCATTT TTGCTGGGGT GGTCCTTCCT 720

CAAGTTCAAC ACCCCAAAAA TGCAAGAAAA AAATACCCAA AGCTAAATGG ATTGTTGGCA 780

GATATAGTTG ATGCTTGTTT ACAAATTGAT CCTGCTCAGA GGACATCATC TACTGATCTT 840

TTGCATCATG AGTATTTTAC TAGAGATGGG TTTATTGAAA AATTCATACC AGAACTGAGA 900

GCTAAATTAC TACAAGAAGC AAAAGTCAAC TCATTCATAA AGCCGAAAGA GAATTCTAAA 960

GAAAATGAAC TTACGAAAGA CGAAAGAAAA ACATCTTATA TCAATACACT GCTAAAACCA 1020

AAAGAGAATT CTAAAGAAAT GGAAAAAGAG AAAAAGCCCA AGGAAATAAA AGTCAGAGTT 1080

ATTAAAGTCA AAGGAGGAAC AGGAGATATC TCAGAACCAA ACAAGATAGA GTGTGAAGGT 1140

GGACATTATC AACAGGATGC CATTGAAAAT GCTCATACTA TGTCTCAAGA TACAAAACCT 1200

GTAATCAATG AACCACCAAA GCCTGTCAAT TCCACTAATT CTAATGGCAT GAAAGATGAT 1260

CCACGTGCTG GAGGAAGTAT GATGATGCCA CCCATCAATC TAACTAGCAA TAATTTGATG 1320

GCTTCAAATC CCAATTCAAA TTTTTCCCAT CCCAGTTCAA GGTTGACTGA ACGAGCAAGA 1380

AAGAGACATA CTTCTTCACA ATCTACTAGA CAGGTATTGT CTAATAGCAG GCAAGAGGAT 1440

GCAGGTCCCA CTCAAAGCCA AATGGAGAAG AGTGTATTTA ATGAGCGAAC AGGTCAAAGT 1500

GACCAAATGG CAAATGGAAA CAAAAGAAAG CTGAATTTTT CCAGATCTGA CAGGAAGGAA 1560

TTCCATTTCC CAGAATTGCC TTTCACAGTA CAGCCCAAGG AGGTGAAAGG AATGGAAGTT 1620

AAACAGATAA AAGTGCTGAA GAGGGAATCA AAGAAAACAG ATTCATCTAA AATACCAACT 1680

TTACTTAATG TGGATCAAAA TCAAGAAAAA CAAGAGGGTG GAGGTGGCCA TTTTAAGGGG 1740

AAGAATTTGA AGAGGAACAG ATTTTTTTTC TGG 1773

Domain Profile

S: 1     yeklgkvGeGsyGvvlkcrnkdtgqivaikkfleseddkevkkialreikllkqlkhenl  60

         ye+lgkvGeGsyG+v+kc++kdtgqivaik f+e+++ k+v+kia+reik+lkq++henl

Q: 4     YETLGKVGEGSYGTVMKCKHKDTGQIVAIKIFYEKPE-KSVNKIATREIKFLKQFHHENL  62

         9***********************************9.9*********************

S: 61    vnllevfrrkkklylvfeyvdktvldelerypnGveeelvkkilyqilkaiefchknnii  120

         vnl+evfr+kkk++lvfe+vd+tvldel++y++G+e+++++++l+qil+aie++h+nnii

Q: 63    VNLIEVFRQKKKIHLVFEFVDHTVLDELQHYCHGLESKRLRRYLFQILRAIEYLHNNNII  122

         ************************************************************

S: 121   hrdikpenilisksgvvklcdfGfarllaapgdvytdyvatrwyrapellvgdtkyGksv  180

         hrdikpenil+s+sg++klcdfGfar+laapg +ytdyvatrwyrapel+++dt+yGk+v

Q: 123   HRDIKPENILVSQSGITKLCDFGFARTLAAPGGIYTDYVATRWYRAPELVLKDTSYGKPV  182

         ************************************************************

S: 181   dvwaiGcllaelltGeplfpgksdvdqlykirktlGeliprhqkifsknevfaGvklpev  240

         d+wa+Gc+++e++tG+p++p++sd+d l+ki+ ++G+l+p+ q+ifsk+++faGv+lp+v

Q: 183   DIWALGCMIIEMATGNPYLPSSSDLDLLHKIVLKVGNLTPHLQNIFSKSPIFAGVVLPQV  242

         ************************************************************

S: 241   edleslekkypklnevlldllkkclkldpaerlsceellkheyf  284

         +++++++kkypkln +l+d++ +cl++dpa+r+s+++ll+heyf

Q: 243   QHPKNARKKYPKLNGLLADIVDACLQIDPAQRTSSTDLLHHEYF  286

         *******************************************9

Domain Sequence
(FASTA)

YETLGKVGEG SYGTVMKCKH KDTGQIVAIK IFYEKPEKSV NKIATREIKF LKQFHHENLV 60

NLIEVFRQKK KIHLVFEFVD HTVLDELQHY CHGLESKRLR RYLFQILRAI EYLHNNNIIH 120

RDIKPENILV SQSGITKLCD FGFARTLAAP GGIYTDYVAT RWYRAPELVL KDTSYGKPVD 180

IWALGCMIIE MATGNPYLPS SSDLDLLHKI VLKVGNLTPH LQNIFSKSPI FAGVVLPQVQ 240

HPKNARKKYP KLNGLLADIV DACLQIDPAQ RTSSTDLLHH EYF 283

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Equus caballus"; ?>Felis catus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Vicugna pacos"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013