EKS-BOT-00487

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-BOT-00487

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/RSKL	306.9	2.5E-91	875	1051	177

Status

Unreviewed

Ensembl Protein

ENSBTAP00000001565

UniProt Accession

E1BB43;

Protein Name

Protein Synonyms/Alias

Gene Name

RPS6KC1

Gene Synonyms/Alias

RPS6KC1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSBTAG00000001181	ENSBTAP00000001565	ENSBTAT00000001565

Organism

Bos taurus

Functional Description

Protein Length

1061

Protein Sequence
(FASTA)

MTSPRERGAD LARFYTVTEP QRHPRGYTVY KVTARVVSRR NPEDVQEIIV WKRYSDFKKL 60

HKELWQIHKN LFRHSELFPP FAKGIVFGRF DETVIEERRQ CAEDLLQFSA NIPALYNSKQ 120

LEDFFKGGII NDGSELIGPV EAYPDSLTDS FPECSTEGFS SDSDLVSLTV DVDSLAELDD 180

GMASNQNSPI RTFGPNLSSD SSVLGTVFSD SEQNKTEEER ESRSLFPSSL KSKLGKRDYL 240

EKAGELIKLA LKKEEEDDYE AASDFYRKGV DLLLEGVQGE SSPTRREAVK RRTAEYLMRA 300

ETLSSLCAKP QLDDVSQPPG SLSSRPPWNL RSPAEELKAF RVLGVIDKVL LVMDTRTEQT 360

FILKGLRKSS EYSRNRKTIV PRCVPNMVCL HKYIVSEESV FLVLQHAEGG KLWSYISKFL 420

NRSPEESFDI EEVKKSSVAK VHLQQPACSP QDSTSFESGG SDGGATLQVL PLKTSLTPSS 480

QDDSNQDDGG QDSSPQWPDS GSSSEEECTT SYLTLCNEYG QEKIEPGSLS EEPFMKAERN 540

DVDTKAIEKF PGQLATDGDS PSRQLKFFPG DDGLEAASSP RTSDSLSRSK NIPMEFFRID 600

SKDSTSELLG LDFGEKLYSL KSEPLKPFFT LSDGESTPRS VRTSESKVEC VAQDTISRGS 660

DDSVPVISFK DAAFDDVSGT DEGRPDLLVN LPGELEPMKD GVAVGPTKFT QTNIGIIESK 720

LLETPDVLCL RLSTEQCQAQ EEKGTEELSD PCGPEAHSIT EKHYVQGDLG MLFLPAVDHS 780

NTGDMSLLDS SESQFQGLSA VESPGTANNT EERLFHISDP LSGANEYNVN TDTLKTEEVL 840

LFTDQADDLA KEEPAIFQRD LEPKQESGLA QEGDKEIHQI FEDLDKKLAL NSRFYIPEGC 900

IQRWAAEMVV ALDALHREGI VCRDLNPNNI LLNDRGHIQL TYFSRWSEVE DSCDSDAIER 960

MYCAPEVGAI TEETEACDWW SLGAVLFELL TGKTLVECHP AGINTHTTLN MPECVSEEAR 1020

SLIQQLLQFN PVERLGAGVA GVEDIKSHPF FTPVDWAELM R 1061

Nucleotide Sequence
(FASTA)

ATGACCTCTC CCCGCGAGCG GGGTGCCGAT CTGGCCCGAT TCTACACTGT CACCGAGCCC 60

CAGCGACACC CGAGGGGCTA CACGGTGTAT AAGGTCACCG CCCGGGTTGT TTCACGAAGA 120

AATCCAGAGG ATGTCCAGGA GATAATCGTA TGGAAGAGAT ATAGTGATTT TAAGAAACTG 180

CACAAAGAAC TATGGCAAAT TCACAAAAAC TTATTTCGAC ATTCAGAATT GTTTCCTCCG 240

TTTGCTAAAG GAATCGTGTT TGGACGATTT GATGAAACTG TTATTGAAGA GAGGAGGCAG 300

TGTGCTGAAG ATCTGCTGCA GTTTTCTGCC AACATTCCTG CCCTTTATAA CAGTAAACAG 360

CTTGAAGATT TTTTCAAGGG TGGGATAATC AATGATGGCT CTGAATTGAT CGGTCCCGTT 420

GAAGCTTATC CGGATTCCCT CACTGATAGC TTTCCTGAGT GCAGCACAGA AGGTTTCTCC 480

AGCGACAGTG ACCTGGTATC TCTTACTGTT GATGTGGATT CTCTTGCTGA GCTGGATGAT 540

GGAATGGCTT CCAATCAGAA TTCTCCCATC AGGACTTTTG GTCCCAATCT TTCTTCGGAT 600

TCTTCAGTGC TAGGGACTGT TTTTTCTGAC AGTGAACAGA ACAAAACAGA AGAAGAACGG 660

GAAAGTCGTA GCCTTTTTCC CAGCAGTTTA AAATCCAAGC TTGGCAAGAG AGATTATTTG 720

GAGAAAGCAG GAGAATTAAT AAAGCTGGCT TTAAAAAAGG AAGAAGAAGA TGACTATGAA 780

GCTGCCTCTG ATTTTTATAG GAAGGGAGTT GATTTGCTCC TGGAAGGTGT TCAAGGAGAG 840

TCAAGCCCCA CCCGGCGAGA AGCTGTGAAG AGAAGAACTG CAGAATATCT CATGCGAGCA 900

GAGACTCTCT CTAGCCTTTG TGCGAAACCT CAGCTCGATG ATGTGTCTCA GCCTCCAGGA 960

TCACTAAGTT CAAGGCCCCC TTGGAACCTA AGGAGCCCTG CCGAGGAGCT GAAGGCCTTC 1020

AGAGTCCTTG GGGTGATTGA CAAGGTTTTA CTTGTAATGG ACACAAGGAC AGAACAGACA 1080

TTTATTTTAA AAGGTCTAAG GAAAAGCAGT GAATACAGCA GGAACAGAAA GACCATCGTC 1140

CCCCGCTGTG TGCCCAACAT GGTGTGCCTG CACAAGTACA TCGTTTCTGA GGAGTCAGTA 1200

TTTCTTGTGC TGCAGCACGC AGAAGGTGGC AAACTCTGGT CATATATCAG TAAGTTTCTC 1260

AACAGAAGTC CTGAAGAAAG CTTTGACATC GAAGAAGTGA AAAAGTCTTC AGTTGCTAAA 1320

GTTCACCTGC AGCAGCCAGC TTGTAGTCCC CAGGACAGCA CCAGCTTTGA ATCCGGAGGA 1380

AGTGATGGTG GAGCCACGCT CCAAGTTCTG CCTTTGAAGA CTAGTCTTAC TCCAAGCTCT 1440

CAGGATGATA GCAACCAAGA TGATGGTGGG CAAGACAGCT CTCCACAATG GCCAGACTCC 1500

GGCTCCAGTT CCGAGGAAGA GTGCACTACT AGCTACTTAA CATTATGCAA TGAGTACGGG 1560

CAAGAGAAGA TTGAACCAGG GTCTTTGAGT GAGGAACCTT TCATGAAGGC TGAAAGGAAT 1620

GATGTTGATA CCAAAGCTAT AGAAAAGTTC CCAGGACAGC TTGCTACTGA CGGCGACAGC 1680

CCCAGCAGAC AGCTGAAGTT CTTCCCTGGA GATGATGGCC TTGAAGCCGC TAGTTCTCCA 1740

AGAACATCAG ATTCCCTCAG TAGATCTAAA AACATCCCCA TGGAATTCTT TAGGATAGAT 1800

AGTAAGGACA GCACTAGTGA ACTCCTAGGA CTTGATTTTG GAGAAAAATT GTATAGTCTA 1860

AAGTCAGAAC CTTTGAAACC GTTCTTCACT CTGTCAGACG GAGAAAGCAC TCCCAGGAGC 1920

GTTAGGACGA GTGAAAGCAA GGTAGAGTGT GTAGCTCAGG ACACGATTAG CAGGGGCTCA 1980

GATGACTCAG TCCCCGTTAT TTCTTTTAAA GATGCTGCTT TTGATGATGT CAGTGGTACT 2040

GATGAAGGAA GGCCTGATCT TCTTGTAAAT CTGCCTGGTG AACTGGAGCC AATGAAAGAT 2100

GGCGTGGCAG TGGGACCTAC TAAGTTCACA CAGACTAATA TAGGCATAAT AGAGAGTAAA 2160

CTGTTGGAAA CCCCTGATGT TTTATGCCTC AGGCTTAGTA CTGAACAGTG CCAAGCACAG 2220

GAAGAAAAAG GCACAGAGGA ACTGAGTGAT CCCTGTGGGC CTGAAGCCCA CAGTATAACA 2280

GAGAAACACT ACGTACAGGG GGATCTTGGG ATGTTATTTT TACCAGCTGT TGATCATAGT 2340

AATACGGGAG ACATGTCTTT GTTAGACAGT TCAGAGTCTC AGTTCCAAGG ACTTAGCGCG 2400

GTTGAGTCAC CAGGAACTGC AAACAACACG GAAGAAAGAT TATTCCACAT TTCTGACCCG 2460

CTCTCAGGTG CTAATGAATA TAACGTAAAT ACAGACACTC TAAAAACTGA AGAAGTCTTG 2520

CTGTTTACAG ATCAGGCTGA TGATTTGGCT AAAGAGGAAC CCGCTATATT TCAGAGAGAC 2580

TTGGAGCCTA AGCAAGAGAG TGGGCTAGCA CAAGAAGGAG ACAAGGAAAT ACACCAGATT 2640

TTTGAGGACC TTGATAAAAA ATTAGCACTG AACTCCAGGT TTTACATCCC AGAAGGCTGC 2700

ATTCAAAGAT GGGCAGCTGA AATGGTGGTA GCCCTTGATG CTTTACATAG AGAGGGGATT 2760

GTGTGCCGCG ATTTGAACCC AAACAACATC TTATTGAATG ATAGAGGACA CATTCAGCTA 2820

ACGTATTTTA GCAGGTGGAG TGAGGTTGAA GATTCCTGTG ACAGCGATGC CATAGAGAGA 2880

ATGTACTGTG CCCCAGAGGT TGGAGCAATC ACGGAAGAAA CTGAAGCCTG TGATTGGTGG 2940

AGTTTGGGTG CTGTCCTCTT TGAACTTCTC ACTGGCAAGA CTCTGGTTGA GTGCCATCCA 3000

GCAGGAATAA ATACTCACAC CACTTTGAAC ATGCCAGAAT GTGTCTCTGA AGAGGCTCGC 3060

TCACTCATTC AACAGCTCTT ACAGTTCAAC CCTGTGGAGC GGCTTGGTGC TGGAGTTGCT 3120

GGTGTTGAAG ATATCAAATC TCATCCGTTT TTTACCCCTG TGGATTGGGC AGAGCTGATG 3180

AGATGA 3186

Domain Profile

S: 188   keiklvsedadkslealsrgldkalqsvdkalslrravwslpEelikqWaaelvvaleaL  247

         kei++++ed+dk+l++ sr                   +++pE++i++Waae+vval+aL

Q: 875   KEIHQIFEDLDKKLALNSR-------------------FYIPEGCIQRWAAEMVVALDAL  915

         4555555555555555555...................99********************

S: 248   HeegvlirDlnadniLldskGhllltYfgrwsevekscrreavdnlysAPEvgaiselte  307

         H+eg+++rDln++niLl+++Gh++ltYf+rwseve+sc+++a++++y+APEvgai+e+te

Q: 916   HREGIVCRDLNPNNILLNDRGHIQLTYFSRWSEVEDSCDSDAIERMYCAPEVGAITEETE  975

         ************************************************************

S: 308   asDwWslGalLyelLtGkalaeahPsgiqahtelqlPevvSeeAkdLleeLLqfePalRl  367

         a+DwWslGa+L+elLtGk+l+e+hP+gi++ht+l++Pe+vSeeA++L+++LLqf+P +Rl

Q: 976   ACDWWSLGAVLFELLTGKTLVECHPAGINTHTTLNMPECVSEEARSLIQQLLQFNPVERL  1035

         ************************************************************

S: 368   GaGeagvdelkaHPFF  383

         GaG+agv+++k+HPFF

Q: 1036  GAGVAGVEDIKSHPFF  1051

         ***************9

Domain Sequence
(FASTA)

KEIHQIFEDL DKKLALNSRF YIPEGCIQRW AAEMVVALDA LHREGIVCRD LNPNNILLND 60

RGHIQLTYFS RWSEVEDSCD SDAIERMYCA PEVGAITEET EACDWWSLGA VLFELLTGKT 120

LVECHPAGIN THTTLNMPEC VSEEARSLIQ QLLQFNPVER LGAGVAGVED IKSHPFF 177

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005769	; C:early endosome
GO:0005524	; F:ATP binding
GO:0035091	; F:phosphatidylinositol binding
GO:0004672	; F:protein kinase activity
GO:0007154	; P:cell communication

KEGG

bta:533192

;

InterPros

IPR011009	; Kinase-like_dom.
IPR007330	; MIT.
IPR001683	; Phox.
IPR000719	; Prot_kinase_cat_dom.

Pfam

PF04212	; MIT; 1.
PF00069	; Pkinase; 1.
PF00787	; PX; 1.

SMARTs

SM00745	; MIT; 1.
SM00312	; PX; 1.

Prosites

PS50011	; PROTEIN_KINASE_DOM; 1.
PS50195	; PX; 1.

Prints

Created Date

20-Feb-2013