EKS-BOT-00498

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-BOT-00498

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Atypical/TIF1	N/A	N/A	N/A	N/A	N/A

Status

Unreviewed

Ensembl Protein

ENSBTAP00000001967

UniProt Accession

F1MNE1;

Protein Name

Protein Synonyms/Alias

Gene Name

TRIM33

Gene Synonyms/Alias

TRIM33;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSBTAG00000001499	ENSBTAP00000001967	ENSBTAT00000001967

Organism

Bos taurus

Functional Description

Protein Length

1126

Protein Sequence
(FASTA)

MAENKGGGEA ESGGGGSSSA PVTAGAAGLA AQEAEPPLAA VLVEEEEEEG GRAGAESGAA 60

GPDDGGVAAA SSGSAPAASA PAASMGPGVP GGAVSTPAPA PASAPAPGPS AGPPPGPPAS 120

LLDTCAVCQQ SLQSRREAEP KLLPCLHSFC LRCLPEPERQ LNVPIPGGSN GDIQQVGVIR 180

CPVCRQECRQ IDLVDNYFVK DTSETPSSSD EKSEQVCTSC EDNASAVGFC VECGEWLCKT 240

CIEAHQRVKF TKDHLIRKKE DVSESVGASG QRPVFCPVHK QEQLKLFCET CDRLTCRDCQ 300

LLEHKEHRYQ FLEEAFQNQK GAIENLLAKL LEKKNYVHFA ATQVQNRIKE VNETNKRVEQ 360

EIKVAIFTLI NEINKKGKSL LQQLENVTKE RQMKLLQQQN DITGLSRQVK HVMNFTNWAI 420

ASGSSTALLY SKRLITFQLR HILKARCDPV PAANGAIRFH CDPTFWAKNV VNLGNLVIES 480

KPAPGYTPNV VVGQVPPGTN HISKTPGQIN LAQLRLQHMQ QQVYAQKQQL QQMRMQQPPA 540

PVPTTTTTTQ QHSRQAAPQM LQQQPPRLIS VQAMQRGNMN CGAFQAHQMR LAQNATRIPG 600

IPRHSGPQYS MMQPHLQRQH SNPGHAGPFP VVSVHNNPVN PTSPTTATMA NANRGPTSPS 660

VTAIELIPSV TNPENLPSLP DIPPIQLEDA GSSSLDNLLS RYISGSHLPP QPTSTMNPSP 720

GPSALSPGSS GLSNSHTPVR PPSTSSTGSR GSCGSSGRTA EKTNLSFKSD QVKVKQEPGT 780

EDEICSFSGA VKQEKTEDGR RSACMLSSPE SSLTPPLSTN LHLESELDTL TSLENHVKTE 840

PADMNESCKQ SGLNSLVNGK SPVRSLMHRS ARIGGDGSSK DDDPNEDWCA VCQNGGDLLC 900

CEKCPKVFHL TCHVPTLLSF PSGDWICTFC RDIGKPEVEY DCDNLQHSKK GKTAQGLSPV 960

DQRKCERLLL YLYCHELSIE FQEPVPASIP NYYKIIKKPM DLSTVKKKLQ KKHSQHYQIP 1020

DDFVADVRLI FKNCERFNEM MKVVQVYAET QEINLKADSE VAQAGKAVAL YFEDKLTEIY 1080

SDRTFAPLPE FEQEEDDGEV TEDSDEDFIQ PRRKRLKSDE RPVHIK 1126

Nucleotide Sequence
(FASTA)

ATGGCGGAAA ACAAAGGCGG CGGCGAGGCT GAGAGCGGCG GCGGGGGCAG CAGTAGCGCG 60

CCGGTAACTG CCGGAGCCGC CGGGCTCGCG GCGCAGGAGG CGGAGCCGCC TCTCGCGGCG 120

GTGCTGGTGG AGGAGGAGGA GGAGGAAGGC GGCAGGGCCG GCGCGGAGAG CGGCGCGGCC 180

GGGCCCGACG ACGGGGGGGT GGCCGCGGCC TCCTCGGGCT CGGCCCCGGC TGCCTCAGCC 240

CCTGCAGCCT CAATGGGCCC TGGAGTTCCC GGGGGGGCGG TATCGACGCC AGCCCCAGCT 300

CCGGCCTCGG CTCCTGCTCC GGGTCCCTCG GCGGGGCCGC CTCCTGGACC GCCAGCCTCG 360

CTCCTGGACA CCTGCGCCGT GTGTCAGCAG AGCCTGCAGA GCCGGCGTGA GGCGGAGCCC 420

AAGCTGTTGC CCTGTCTTCA CTCCTTCTGC CTGCGCTGCC TGCCTGAGCC CGAGCGCCAA 480

CTCAACGTGC CCATCCCGGG GGGCAGCAAC GGCGACATCC AGCAAGTTGG TGTAATACGG 540

TGCCCAGTAT GCCGCCAAGA ATGCAGACAA ATAGACCTTG TGGATAATTA TTTTGTGAAA 600

GATACATCTG AAACCCCTAG CAGTTCTGAT GAGAAGTCAG AACAGGTATG TACTAGTTGT 660

GAAGACAATG CGAGTGCAGT TGGCTTTTGT GTCGAGTGTG GAGAATGGCT ATGTAAGACA 720

TGCATTGAAG CACATCAAAG AGTAAAATTC ACTAAGGATC ACTTGATCAG GAAGAAAGAA 780

GATGTCTCAG AGTCTGTTGG AGCATCTGGT CAGCGCCCTG TTTTCTGCCC TGTTCACAAA 840

CAAGAACAGT TGAAACTTTT CTGTGAAACG TGTGATAGAC TGACATGTAG AGACTGTCAG 900

CTATTGGAAC ACAAAGAACA TAGGTATCAG TTTTTGGAAG AAGCTTTTCA AAACCAGAAA 960

GGTGCAATTG AGAATCTACT GGCTAAGCTT CTTGAGAAGA AGAATTATGT TCATTTTGCA 1020

GCTACTCAGG TGCAGAATAG GATAAAAGAA GTAAATGAGA CTAACAAACG AGTAGAACAG 1080

GAAATTAAAG TGGCCATTTT CACCCTTATC AATGAAATTA ATAAGAAAGG AAAATCTCTC 1140

TTACAGCAGC TAGAGAATGT TACAAAAGAA AGACAGATGA AGTTACTACA GCAACAGAAT 1200

GACATCACAG GCCTTTCCCG GCAGGTGAAA CACGTTATGA ACTTTACTAA CTGGGCAATT 1260

GCAAGTGGTA GCAGCACGGC ACTACTGTAC AGCAAGCGAC TGATTACTTT TCAGTTGCGC 1320

CATATTTTGA AAGCACGGTG TGATCCTGTC CCTGCTGCTA ATGGAGCAAT ACGTTTCCAT 1380

TGTGATCCTA CCTTTTGGGC AAAGAATGTA GTCAATTTAG GTAATCTAGT AATAGAGAGT 1440

AAACCAGCTC CTGGTTATAC TCCTAATGTT GTAGTTGGGC AAGTTCCTCC AGGGACAAAC 1500

CACATTAGTA AAACCCCTGG ACAGATTAAC TTAGCACAGC TTCGCCTTCA ACATATGCAA 1560

CAGCAAGTGT ATGCACAGAA ACAGCAGTTG CAGCAGATGA GGATGCAGCA GCCACCTGCA 1620

CCCGTACCAA CAACAACAAC AACAACACAG CAGCACTCCA GACAGGCAGC CCCTCAGATG 1680

TTACAGCAAC AGCCTCCAAG ATTGATCAGT GTTCAAGCAA TGCAAAGAGG CAACATGAAT 1740

TGTGGAGCTT TCCAAGCCCA TCAAATGAGA TTGGCTCAGA ATGCTACCCG AATACCAGGG 1800

ATACCCAGGC ACAGCGGCCC TCAGTATTCC ATGATGCAGC CACATCTCCA AAGACAACAT 1860

TCAAACCCAG GGCATGCTGG ACCCTTTCCT GTTGTGTCAG TACATAACAA CCCAGTCAAT 1920

CCAACCAGCC CTACTACAGC TACTATGGCG AATGCAAATC GAGGTCCCAC CAGCCCATCT 1980

GTTACTGCAA TAGAATTAAT TCCTTCGGTT ACCAATCCAG AAAACCTGCC ATCGCTGCCA 2040

GATATTCCAC CTATACAGTT GGAAGATGCT GGTTCAAGTA GTTTAGATAA TCTACTAAGT 2100

AGATACATCT CAGGCAGTCA CCTACCCCCA CAGCCCACAA GCACCATGAA TCCCTCCCCA 2160

GGACCCTCTG CCCTATCTCC AGGATCATCA GGTTTATCCA ATTCTCACAC ACCTGTGAGA 2220

CCCCCTAGTA CTTCTAGTAC TGGTAGTCGA GGCAGCTGTG GGTCATCAGG AAGAACTGCT 2280

GAGAAGACCA ATCTTAGTTT TAAGTCTGAT CAAGTGAAGG TCAAGCAAGA ACCTGGCACT 2340

GAAGATGAAA TATGTAGCTT TTCAGGAGCT GTGAAACAGG AAAAGACTGA GGATGGCAGA 2400

CGGAGTGCCT GCATGTTGAG CAGTCCTGAG AGTAGCTTGA CACCACCTCT TTCAACCAAC 2460

CTGCATCTAG AGAGTGAGTT GGATACATTA ACAAGCCTGG AAAACCACGT GAAAACTGAA 2520

CCTGCAGATA TGAATGAAAG CTGCAAACAG TCAGGGCTCA ACAGCCTTGT TAATGGAAAG 2580

TCCCCAGTTC GAAGCCTCAT GCACAGGTCC GCAAGGATTG GAGGAGATGG CAGCAGCAAA 2640

GATGATGACC CAAATGAAGA TTGGTGTGCT GTCTGCCAAA ATGGAGGAGA TCTCTTGTGC 2700

TGTGAAAAAT GTCCAAAGGT CTTTCATCTA ACTTGTCATG TTCCAACACT TCTTAGCTTT 2760

CCAAGTGGGG ACTGGATATG CACATTTTGC AGAGATATTG GGAAGCCAGA AGTTGAATAC 2820

GATTGTGATA ATTTGCAACA TAGTAAGAAG GGGAAAACTG CACAGGGCTT AAGCCCCGTG 2880

GACCAAAGGA AATGTGAACG TCTTCTGCTT TACCTCTATT GCCATGAATT AAGTATTGAA 2940

TTCCAGGAAC CAGTTCCTGC TTCGATACCA AACTACTATA AAATTATAAA GAAACCAATG 3000

GATTTATCCA CCGTGAAAAA GAAGCTTCAG AAAAAACATT CCCAACACTA CCAAATCCCA 3060

GATGATTTTG TGGCTGATGT TCGTTTGATC TTCAAGAACT GTGAAAGGTT TAATGAAATG 3120

ATGAAAGTTG TTCAAGTTTA TGCAGAAACA CAAGAGATTA ATTTGAAGGC TGATTCAGAA 3180

GTAGCTCAGG CAGGGAAAGC AGTTGCATTG TACTTTGAAG ATAAACTCAC AGAGATCTAC 3240

TCAGACAGGA CCTTCGCACC TTTGCCAGAG TTTGAGCAGG AAGAGGATGA TGGTGAGGTA 3300

ACTGAGGACT CTGATGAAGA CTTTATTCAG CCCCGCAGAA AACGCCTAAA GTCAGATGAG 3360

AGACCAGTAC ATATAAAGTA A 3381

Domain Profile

N/A

Domain Sequence
(FASTA)

N/A

Keyword

Complete proteome; Metal-binding; Reference proteome; Zinc; Zinc-finger.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Myotis lucifugus"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005634	; C:nucleus
GO:0008270	; F:zinc ion binding
GO:0030514	; P:negative regulation of BMP signaling pathway
GO:0017015	; P:regulation of transforming growth factor beta receptor signaling pathway

KEGG

bta:533296

;

InterPros

IPR003649	; Bbox_C.
IPR001487	; Bromodomain.
IPR019786	; Zinc_finger_PHD-type_CS.
IPR000315	; Znf_B-box.
IPR011011	; Znf_FYVE_PHD.
IPR001965	; Znf_PHD.
IPR019787	; Znf_PHD-finger.
IPR001841	; Znf_RING.
IPR013083	; Znf_RING/FYVE/PHD.
IPR017907	; Znf_RING_CS.

Pfam

PF00439	; Bromodomain; 1.
PF00628	; PHD; 1.
PF00643	; zf-B_box; 2.
PF13639	; zf-RING_2; 1.

SMARTs

SM00502	; BBC; 1.
SM00336	; BBOX; 2.
SM00297	; BROMO; 1.
SM00249	; PHD; 2.
SM00184	; RING; 2.

Prosites

PS50014	; BROMODOMAIN_2; 1.
PS50119	; ZF_BBOX; 2.
PS01359	; ZF_PHD_1; 1.
PS50016	; ZF_PHD_2; 1.
PS00518	; ZF_RING_1; 1.
PS50089	; ZF_RING_2; 1.

Prints

PR00503

; BROMODOMAIN.

Created Date

20-Feb-2013