EKS-BOT-00060

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-BOT-00060

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDK	392.0	1.5E-117	195	476	282

Status

Unreviewed

Ensembl Protein

ENSBTAP00000001977

UniProt Accession

F1MN42;

Protein Name

Protein Synonyms/Alias

Gene Name

CDK17

Gene Synonyms/Alias

CDK17;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSBTAG00000001510	ENSBTAP00000001977	ENSBTAT00000001977

Organism

Bos taurus

Functional Description

Protein Length

526

Protein Sequence
(FASTA)

VDRMKKFKRR LSLTLRGSQT IDESLSELAE QMTIEENSSK DNEPIVKNGR PPTSHSMHSF 60

LHQYTGSFKK PPLRRPHSVI GGSLGSFMAM PRNGSRLDIV HENLKMGSDG ESDQASGTSS 120

DEVQSPTGVC LRNRIHRRIS IEDLNKRLSL PADIRIPDGY LEKLQINSPP FDQPMSRRSR 180

RASLSEIGFG KMETYIKLEK LGEGTYATVY KGRSKLTENL VALKEIRLEH EEGAPCTAIR 240

EVSLLKDLKH ANIVTLHDIV HTDKSLTLVF EYLDKDLKQY MDDCGNIMSM HNVKLFLYQI 300

LRGLAYCHRR KVLHRDLKPQ NLLINEKGEL KLADFGLARA KSVPTKTYSN EVVTLWYRPP 360

DVLLGSSEYS TQIDMWGVGC IFFEMASGRP LFPGSTVEDE LHLIFRLLGT PSQENWPGVS 420

SNDEFKNYNF PKYKPQPLIN HAPRLDSEGI ELITKFLQYE SKKRVSAEEA MKHVYFRSLG 480

PRIHALPESV SIFSLKEIQL QKDPGFRNSS YPETGHAKTE KHSALF 526

Nucleotide Sequence
(FASTA)

GTTGATAGGA TGAAAAAATT TAAGAGAAGG CTATCCCTCA CGCTTCGAGG AAGCCAGACT 60

ATTGATGAAT CGTTATCTGA ATTGGCTGAG CAAATGACTA TTGAAGAAAA CAGCAGCAAA 120

GATAATGAGC CTATCGTGAA GAATGGCAGG CCTCCGACCT CGCACAGTAT GCATTCCTTC 180

CTCCACCAGT ACACAGGGTC CTTTAAGAAG CCCCCATTGC GGAGACCACA TAGCGTTATT 240

GGAGGAAGCC TTGGTTCCTT CATGGCAATG CCCAGAAATG GAAGCAGATT AGATATTGTT 300

CATGAAAATC TAAAAATGGG ATCAGATGGC GAGAGTGACC AAGCTTCTGG GACATCATCT 360

GATGAAGTCC AGTCACCTAC GGGTGTTTGT CTTAGAAATC GTATACATAG GCGGATCTCA 420

ATAGAGGATT TAAATAAGCG GTTATCACTG CCTGCAGATA TCAGAATACC TGATGGGTAT 480

CTTGAAAAGT TGCAGATAAA CAGTCCACCA TTTGATCAAC CAATGAGCCG AAGGTCTCGG 540

AGAGCTTCCT TATCAGAAAT TGGGTTTGGA AAAATGGAAA CCTACATCAA ATTGGAAAAG 600

CTTGGAGAGG GTACCTATGC AACAGTTTAT AAAGGAAGAA GTAAATTGAC AGAGAATTTG 660

GTGGCCTTGA AAGAGATCCG GTTGGAACAT GAAGAAGGTG CACCCTGCAC AGCAATAAGA 720

GAAGTTTCAC TATTAAAGGA TCTAAAACAT GCAAATATAG TAACATTACA TGACATTGTT 780

CATACAGATA AATCTTTGAC TCTGGTCTTT GAGTATCTGG ATAAAGATCT AAAACAGTAC 840

ATGGATGACT GTGGAAACAT CATGAGTATG CACAACGTAA AGCTGTTTTT ATACCAAATT 900

CTACGTGGTT TGGCATATTG CCACAGAAGA AAGGTGTTAC ACCGAGATTT AAAACCACAG 960

AACCTCCTCA TTAATGAAAA AGGAGAATTA AAGCTAGCAG ATTTTGGACT AGCCAGAGCC 1020

AAGTCAGTTC CCACAAAGAC CTACTCAAAT GAAGTTGTCA CACTTTGGTA CCGGCCGCCT 1080

GATGTGCTTC TGGGTTCCTC AGAGTACTCA ACACAGATTG ACATGTGGGG TGTTGGTTGC 1140

ATTTTCTTTG AAATGGCTTC TGGAAGACCT CTGTTTCCAG GATCAACTGT GGAAGATGAA 1200

CTGCACTTAA TTTTCCGACT GCTAGGAACT CCATCTCAGG AAAATTGGCC CGGTGTTTCT 1260

TCAAATGATG AGTTCAAGAA CTACAACTTT CCAAAATATA AACCACAGCC TCTAATTAAC 1320

CACGCACCCA GGTTAGACTC TGAAGGAATT GAGTTGATAA CAAAATTTCT TCAGTATGAA 1380

TCTAAGAAAA GGGTTTCAGC AGAAGAGGCC ATGAAACATG TGTACTTTCG AAGTCTGGGA 1440

CCGAGAATAC ATGCTTTACC TGAAAGTGTA TCAATATTCA GTTTGAAAGA GATTCAGTTG 1500

CAAAAGGACC CCGGTTTTCG AAATTCTTCT TATCCAGAGA CAGGACATGC GAAGACTGAG 1560

AAACACAGTG CATTATTT 1578

Domain Profile

S: 1     yeklekigeGtygkvykakdketgevvAlKkirlekekegvpitalrEisllkelkhkni  60

         y klek+geGty++vyk+++k t+++vAlK+irle+e eg p+ta+rE+sllk+lkh+ni

Q: 195   YIKLEKLGEGTYATVYKGRSKLTENLVALKEIRLEHE-EGAPCTAIREVSLLKDLKHANI  253

         7799********************************9.9*********************

S: 61    vkLlevvakdkkklyLvfefleqdLkkllkkkkkkklsleevkslllqlleglaylHsnk  120

         v+L+++v+ ++k+l+Lvfe+l++dLk++++++ +  +s+++vk +l+q+l+glay+H++k

Q: 254   VTLHDIVH-TDKSLTLVFEYLDKDLKQYMDDCGN-IMSMHNVKLFLYQILRGLAYCHRRK  311

         ********.99***********************.*************************

S: 121   ilHRDlKpqNlLiskegklklaDfGlarafssplktytkevvTlwYraPelLlgakeYst  180

         +lHRDlKpqNlLi+++g+lklaDfGlara s+p+kty++evvTlwYr+P++Llg++eYst

Q: 312   VLHRDLKPQNLLINEKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSSEYST  371

         ************************************************************

S: 181   avDiWsvgcilaelltrkplfqgkseidqlerifkllgtpsekvwpevsklpeyk.ksfp  239

         ++D+W+vgci+ e+++ +plf+g++  d+l+ if+llgtps+++wp+vs+  e+k ++fp

Q: 372   QIDMWGVGCIFFEMASGRPLFPGSTVEDELHLIFRLLGTPSQENWPGVSSNDEFKnYNFP  431

         *******************************************************99***

S: 240   kkkkkklkekvkklkekaldllekllaldpkkRisakealqhkyf  284

         k+k++ l ++ ++l++++++l++k+l+++ kkR+sa+ea++h yf

Q: 432   KYKPQPLINHAPRLDSEGIELITKFLQYESKKRVSAEEAMKHVYF  476

         ********************************************8

Domain Sequence
(FASTA)

YIKLEKLGEG TYATVYKGRS KLTENLVALK EIRLEHEEGA PCTAIREVSL LKDLKHANIV 60

TLHDIVHTDK SLTLVFEYLD KDLKQYMDDC GNIMSMHNVK LFLYQILRGL AYCHRRKVLH 120

RDLKPQNLLI NEKGELKLAD FGLARAKSVP TKTYSNEVVT LWYRPPDVLL GSSEYSTQID 180

MWGVGCIFFE MASGRPLFPG STVEDELHLI FRLLGTPSQE NWPGVSSNDE FKNYNFPKYK 240

PQPLINHAPR LDSEGIELIT KFLQYESKKR VSAEEAMKHV YF 282

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Callithrix jacchus"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013