EKS-BOT-00388

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-BOT-00388

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
STE/STE11	364.2	4.9E-109	369	629	261

Status

Unreviewed

Ensembl Protein

ENSBTAP00000005525

UniProt Accession

F1MSX4;

Protein Name

Protein Synonyms/Alias

Gene Name

Bt.92459

Gene Synonyms/Alias

Bt.92459;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSBTAG00000004216	ENSBTAP00000005525	ENSBTAT00000005525

Organism

Bos taurus

Functional Description

Protein Length

632

Protein Sequence
(FASTA)

LDDQQALNSI MQDLAVLHKA SRPALSLQET RKTKSSSPKK QNDVRVKFEH RGEKRILQFP 60

RPVKLEDLRS KAKIAFGQSM DLHYTNNELV IPLTTQDDLD KAVELLDRSI HMKSLKILLV 120

INGSAQRASS PFFNVGQHLY IILQKNAGSL INLIMQLSAG RRTYYLTSPT SRDRSSPPPG 180

YIPDELHQVA RNGSFTSINS EGEFIPESMD QTMLDPLSLS SPENSGSGSC PSLDSPLDGE 240

SYPKSRMPRA QSYPDNHQEF SDYDNPIFEK FGKGGTYPRR YHISYHHQDY NDGRKTFPRA 300

RRTQGTSFRS PVSFSPTDHS LSTSSGSSIF TPEYDESRIR RRGSDIDNPT LTVMDISPPS 360

RSPRAPTNWR LGKLLGQGAF GRVYLCYDVD TGRELAVKQV QFDPDSPETS KEVNALECEI 420

QLLKNLLHER IVQYYGCLRD PQEKTLSIFM EYMPGGSIKD QLKAYGALTE NVTRKYTRQI 480

LEGVHYLHSN MIVHRDIKGA NILRDSTGNV KLGDFGASKR LQTICLSGTG MKSVTGTPYW 540

MSPEVISGEG YGRKADIWSV GCTVVEMLTE KPPWAEFEAM AAIFKIATQP TNPKLPPHVS 600

DYTRDFLKRI FVEAKLRPPA DDLLRHTFVH CH 632

Nucleotide Sequence
(FASTA)

CTAGATGATC AGCAAGCTTT GAACTCAATC ATGCAAGATT TGGCTGTTCT TCATAAGGCC 60

AGTCGACCAG CATTATCCTT ACAGGAAACC AGAAAAACAA AGTCCTCATC ACCAAAAAAG 120

CAGAATGATG TTCGAGTCAA ATTTGAACAC AGAGGAGAAA AAAGAATCCT TCAGTTCCCC 180

AGACCAGTTA AACTGGAAGA CCTGAGGTCT AAAGCTAAAA TTGCCTTTGG ACAGTCTATG 240

GATCTGCATT ATACCAATAA TGAGTTGGTA ATTCCATTAA CCACCCAAGA TGACTTGGAC 300

AAGGCTGTGG AACTGCTGGA TCGTAGTATT CATATGAAGA GCCTCAAAAT ATTACTTGTA 360

ATAAATGGAA GTGCACAGAG AGCTTCATCT CCATTCTTTA ATGTAGGGCA ACACCTGTAC 420

ATAATCCTGC AAAAAAATGC CGGTTCACTT ATCAACCTCA TAATGCAGTT GTCAGCAGGC 480

AGAAGAACAT ACTACCTAAC AAGTCCCACT AGTAGAGATA GAAGCTCCCC TCCCCCTGGA 540

TACATTCCAG ATGAGTTACA CCAGGTTGCC CGGAATGGGT CATTTACCAG TATCAACAGT 600

GAAGGAGAGT TCATCCCAGA GAGCATGGAC CAAACAATGC TGGACCCATT ATCTTTAAGC 660

AGCCCTGAAA ATTCTGGCTC AGGAAGTTGT CCATCACTTG ATAGCCCTCT GGATGGAGAG 720

AGCTATCCAA AATCACGAAT GCCTAGGGCA CAGAGCTACC CAGATAATCA TCAGGAATTT 780

TCAGACTATG ATAACCCTAT CTTTGAAAAA TTTGGAAAAG GAGGAACTTA TCCAAGAAGG 840

TATCATATTT CTTATCACCA TCAAGACTAT AATGATGGTC GTAAAACTTT TCCAAGAGCT 900

AGAAGGACCC AGGGGACCAG CTTCCGCTCT CCTGTGAGTT TCAGTCCTAC TGACCACTCC 960

TTAAGCACCA GTAGTGGAAG CAGTATCTTT ACCCCGGAGT ACGATGAGAG TCGAATAAGA 1020

AGAAGGGGAA GTGACATAGA CAATCCTACT TTGACTGTAA TGGACATTAG CCCACCCAGC 1080

CGCTCACCTC GTGCTCCAAC CAACTGGAGA TTGGGCAAAT TACTTGGCCA GGGAGCCTTT 1140

GGCAGGGTCT ACCTCTGTTA CGATGTTGAT ACAGGAAGAG AATTGGCTGT TAAACAAGTT 1200

CAGTTTGACC CAGATAGTCC TGAGACCAGC AAGGAAGTAA ATGCACTTGA GTGTGAAATT 1260

CAGTTGTTGA AAAACTTGCT GCATGAGCGA ATTGTTCAGT ATTATGGCTG TTTGAGGGAT 1320

CCCCAAGAAA AAACACTTTC CATATTTATG GAATATATGC CAGGGGGCTC CATTAAGGAC 1380

CAATTAAAAG CATATGGAGC TCTTACTGAG AATGTGACCC GGAAATACAC CCGTCAGATT 1440

CTTGAGGGAG TTCATTATTT GCACAGTAAT ATGATTGTTC ATAGAGATAT AAAAGGCGCA 1500

AATATTCTGC GAGATTCAAC AGGCAACGTC AAACTAGGAG ATTTTGGGGC CAGCAAACGG 1560

CTTCAAACCA TCTGTCTTTC AGGGACGGGA ATGAAGTCTG TGACAGGCAC ACCGTATTGG 1620

ATGAGCCCTG AAGTGATTAG TGGAGAAGGC TATGGCAGAA AAGCAGATAT CTGGAGCGTG 1680

GGCTGTACTG TGGTAGAAAT GCTAACTGAA AAGCCTCCTT GGGCCGAGTT TGAAGCGATG 1740

GCTGCCATCT TTAAAATCGC CACTCAGCCA ACGAACCCAA AGCTGCCACC TCATGTCTCC 1800

GACTATACTC GAGACTTCCT CAAACGGATT TTTGTAGAGG CCAAACTGAG GCCGCCCGCC 1860

GACGACCTGC TGAGGCACAC GTTTGTGCAC TGCCACTAG 1899

Domain Profile

S: 1     wqkrevigkGsfgsvyaaldvdtgellavKeveikpekksekkevkalkeEikllkelkH  60

         w+ ++++g+G+fg+vy+++dvdtg+ lavK+v+++p++ +++kev+al++Ei+llk+l H

Q: 369   WRLGKLLGQGAFGRVYLCYDVDTGRELAVKQVQFDPDSPETSKEVNALECEIQLLKNLLH  428

         78899*******************************************************

S: 61    enivkyyGv..eveeeelkiflEyvegGslssllekygkleesvikkytkqileglayLH  118

         e+iv+yyG+  + +e++l+if+Ey++gGs++++l++yg+l+e+v++kyt+qileg++yLH

Q: 429   ERIVQYYGClrDPQEKTLSIFMEYMPGGSIKDQLKAYGALTENVTRKYTRQILEGVHYLH  488

         *********777899*********************************************

S: 119   ekkivHRDiKgaNilldssgvvklsDFGaskrlaelntkaaelesltGtlaymaPEvikk  178

         +++ivHRDiKgaNil ds+g+vkl+DFGaskrl++++ + + ++s+tGt+++m+PEvi++

Q: 489   SNMIVHRDIKGANILRDSTGNVKLGDFGASKRLQTICLSGTGMKSVTGTPYWMSPEVISG  548

         **********************************************************99

S: 179   kekgygrkaDiWslgcvviemltgkrPfaeldeelaimfkvgakktkPeipeklseegkd  238

         +  gygrkaDiWs+gc+v+emlt+k+P+ae+ e++a++fk++++ t+P++p ++s+ ++d

Q: 549   E--GYGRKADIWSVGCTVVEMLTEKPPWAEF-EAMAAIFKIATQPTNPKLPPHVSDYTRD  605

         8..****************************.9***************************

S: 239   flekcleldpkkrpsaeeLLkhefl  263

         fl++++ +++k rp a++LL+h+f+

Q: 606   FLKRIF-VEAKLRPPADDLLRHTFV  629

         ******.899*************96

Domain Sequence
(FASTA)

WRLGKLLGQG AFGRVYLCYD VDTGRELAVK QVQFDPDSPE TSKEVNALEC EIQLLKNLLH 60

ERIVQYYGCL RDPQEKTLSI FMEYMPGGSI KDQLKAYGAL TENVTRKYTR QILEGVHYLH 120

SNMIVHRDIK GANILRDSTG NVKLGDFGAS KRLQTICLSG TGMKSVTGTP YWMSPEVISG 180

EGYGRKADIW SVGCTVVEML TEKPPWAEFE AMAAIFKIAT QPTNPKLPPH VSDYTRDFLK 240

RIFVEAKLRP PADDLLRHTF V 261

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004672	; F:protein kinase activity
GO:0071260	; P:cellular response to mechanical stimulus
GO:0045893	; P:positive regulation of transcription, DNA-dependent

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000270	; OPR_PB1.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.

Pfam

PF00564	; PB1; 1.
PF00069	; Pkinase; 1.

SMARTs

SM00666	; PB1; 1.
SM00220	; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.

Prints

Created Date

20-Feb-2013