EKS-BOT-00428

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-BOT-00428

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/WEE	325.9	1.8E-97	110	359	250

Status

Unreviewed

Ensembl Protein

ENSBTAP00000006206

UniProt Accession

F1MKK7;

Protein Name

Protein Synonyms/Alias

Gene Name

PKMYT1

Gene Synonyms/Alias

PKMYT1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSBTAG00000004729	ENSBTAP00000006206	ENSBTAT00000006206

Organism

Bos taurus

Functional Description

Protein Length

506

Protein Sequence
(FASTA)

LPPGAPVLDM LMPAEGTPPP LGGTPVPVPA YFRHAEPGFS LKRPRGLSRS LPPRPPAKGS 60

IPVSRLFPPR TPGWHQPHAR RVSFRDQASE PLQSPGYDPS RPESFFQQSF HRLGRLGHGS 120

YGEVFKVRSK EDGRLYAVKR SMSPFRGPKD RTRKLAEVGG HEKVGQHPRC VRLEQAWEEG 180

GILYLQTELC GPSLQQHCEA WGASLPETQV WGYLRDTLLA LAHLHGQGLV HLDVKPANIF 240

LGPRGRCKLG DFGLLVELGA SGTSEAQEGD PRYMAPELLQ GSYGTAADVF SLGLTILEVA 300

CNMELPRGGE GWQRLRQGYL PPEFTAGLSS ELRSVLVTML EPDPKLRATA EALLALPVLR 360

QPRPWSVLWF MAAEALSRGW ALWQALLSLL CWLWHGLAHP ASWLQPPGPP ATPPGSPPCG 420

LLLDRSLSST WDDDSIGPSL SPEAVLARAA SSTSTPCSGS PAPRSRHTPR DALDLSDIDS 480

EPPRGTFPAF EPRNLLSLFE DSLGPS 506

Nucleotide Sequence
(FASTA)

CTGCCTCCCG GGGCGCCTGT GCTGGACATG CTCATGCCCG CCGAGGGCAC CCCGCCACCC 60

CTGGGTGGCA CTCCCGTCCC AGTCCCAGCC TACTTCCGCC ATGCAGAACC TGGCTTCTCC 120

CTCAAGAGGC CCAGAGGGCT CAGCCGGAGC CTCCCACCCC GGCCCCCTGC CAAGGGCAGC 180

ATCCCCGTCA GCCGCCTCTT CCCTCCTCGG ACCCCAGGCT GGCATCAGCC CCACGCCCGG 240

CGGGTGTCGT TCCGGGACCA GGCCTCTGAG CCCCTGCAGA GCCCCGGGTA TGACCCAAGC 300

CGACCAGAGT CCTTCTTCCA GCAGAGTTTC CACAGGCTCG GCCGCCTGGG CCACGGCTCT 360

TATGGGGAGG TCTTCAAGGT GCGCTCCAAG GAAGATGGCC GGCTCTATGC AGTGAAGCGC 420

TCCATGTCGC CGTTCCGGGG CCCCAAGGAC CGGACCCGCA AGCTGGCCGA GGTGGGTGGC 480

CATGAGAAGG TGGGGCAGCA CCCGCGCTGT GTGCGGCTGG AGCAAGCCTG GGAGGAGGGC 540

GGCATCCTGT ACCTACAGAC GGAGCTGTGT GGGCCCAGCC TGCAGCAGCA CTGTGAGGCC 600

TGGGGCGCCA GCCTGCCCGA AACCCAGGTC TGGGGCTACC TGCGGGATAC CCTGCTGGCC 660

CTGGCCCACC TGCACGGCCA GGGCCTGGTC CACCTGGACG TCAAGCCTGC CAACATCTTC 720

CTGGGACCCC GGGGCCGCTG CAAGCTGGGC GACTTTGGGC TGCTGGTCGA GCTGGGCGCG 780

TCGGGAACTA GCGAGGCCCA GGAAGGAGAC CCCCGCTACA TGGCCCCCGA GCTGCTCCAG 840

GGCTCTTACG GGACAGCAGC AGACGTGTTC AGCCTGGGCC TCACCATCCT GGAGGTGGCA 900

TGCAACATGG AGCTGCCCCG CGGTGGGGAG GGCTGGCAGC GGCTGCGTCA GGGCTATCTG 960

CCCCCTGAGT TCACGGCTGG GCTGTCCTCT GAGCTGCGTT CTGTCCTCGT CACGATGCTG 1020

GAGCCTGACC CCAAGCTGCG GGCCACCGCC GAGGCCCTGC TGGCCCTGCC CGTGCTCAGG 1080

CAGCCACGGC CCTGGAGCGT CCTGTGGTTC ATGGCCGCCG AGGCCCTCAG TCGAGGCTGG 1140

GCCCTGTGGC AGGCCCTGCT CTCCCTGCTC TGCTGGCTCT GGCACGGGCT GGCGCACCCC 1200

GCCAGCTGGC TGCAGCCCCC GGGTCCGCCG GCCACCCCAC CTGGGTCGCC GCCCTGTGGC 1260

CTCCTCCTGG ACCGCAGCCT CTCCAGCACC TGGGACGACG ACAGCATAGG GCCCTCGCTG 1320

TCTCCAGAGG CCGTTCTGGC CAGGGCTGCC AGCAGCACCT CCACCCCCTG CAGTGGCTCC 1380

CCTGCCCCCC GGAGCAGGCA CACGCCAAGG GATGCTCTGG ACCTGAGTGA CATTGACTCA 1440

GAGCCCCCTC GGGGCACCTT CCCCGCCTTT GAACCTCGGA ACCTCCTCAG CCTGTTTGAG 1500

GACTCCCTGG GCCCGAGCTA A 1521

Domain Profile

S: 1     FeevekiGkGefgevfkvvkredgklyAikkskkplkglskekkalrEvtahavlgqhen  60

         F+++ ++G+G++gevfkv+++edg+lyA+k+s++p++g ++++++l+Ev +h+++gqh+

Q: 110   FHRLGRLGHGSYGEVFKVRSKEDGRLYAVKRSMSPFRGPKDRTRKLAEVGGHEKVGQHPR  169

         89999*******************************************************

S: 61    vvryisaWeeddslyiqtElCeggsLeaalqeceakkkaleeaelkkilldlllglrylH  120

         +vr+ +aWee ++ly+qtElC g sL+++   cea+ ++l+e++++ +l d ll+l +lH

Q: 170   CVRLEQAWEEGGILYLQTELC-GPSLQQH---CEAWGASLPETQVWGYLRDTLLALAHLH  225

         *********************.*******...****************************

S: 121   ssslvHlDikpenifitkevtlklgDlGlvtelnsedkskveEGDsrylakEilqeeysk  180

          + lvHlD+kp+nif+  ++++klgD+Gl++el+++ +s+++EGD ry+a+E+lq++y +

Q: 226   GQGLVHLDVKPANIFLGPRGRCKLGDFGLLVELGASGTSEAQEGDPRYMAPELLQGSYGT  285

         ************************************************************

S: 181   lkaDiFslgltilevaanvelPsnGeaWhklRkgklpdeilkelsedlrellklmlepdp  240

         + aD+Fslgltileva+n+elP+ Ge W++lR+g+lp+e+++ ls++lr++l +mlepdp

Q: 286   A-ADVFSLGLTILEVACNMELPRGGEGWQRLRQGYLPPEFTAGLSSELRSVLVTMLEPDP  344

         *.**********************************************************

S: 241   erRptaeellkhevl  255

         + R+tae+ll+ +vl

Q: 345   KLRATAEALLALPVL  359

         **********98875

Domain Sequence
(FASTA)

FHRLGRLGHG SYGEVFKVRS KEDGRLYAVK RSMSPFRGPK DRTRKLAEVG GHEKVGQHPR 60

CVRLEQAWEE GGILYLQTEL CGPSLQQHCE AWGASLPETQ VWGYLRDTLL ALAHLHGQGL 120

VHLDVKPANI FLGPRGRCKL GDFGLLVELG ASGTSEAQEG DPRYMAPELL QGSYGTAADV 180

FSLGLTILEV ACNMELPRGG EGWQRLRQGY LPPEFTAGLS SELRSVLVTM LEPDPKLRAT 240

AEALLALPVL 250

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gasterosteus aculeatus"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005737	; C:cytoplasm
GO:0005634	; C:nucleus
GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0010923	; P:negative regulation of phosphatase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013