EKS-BOT-00206

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-BOT-00206

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDKL	528.3	3.6E-159	4	287	284

Status

Unreviewed

Ensembl Protein

ENSBTAP00000035910

UniProt Accession

A6QLF0;

Protein Name

Protein Synonyms/Alias

CDKL1 protein;

Gene Name

CDKL1

Gene Synonyms/Alias

CDKL1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSBTAG00000004780	ENSBTAP00000035910	ENSBTAT00000036046

Organism

Bos taurus

Functional Description

Protein Length

352

Protein Sequence
(FASTA)

MEKYEKIGKI GEGSYGVVFK CRNRDTGQIV AIKKFLESED DPVIKKIALR EIRMLKQLKH 60

PNLVNLIEVF RRKRRLHLVF EYCDHTVLHE LDRHQRGVPE HLVKSITWQT LQAVNFCHKH 120

SCIHRDVKPE NILVTKQSVI KLCDFGFARL LTGPSDYYTD YVATRWYRSP ELLVGDTQYG 180

PPVDVWAIGC VFAELLSGVP LWPGKSDVDQ LYLIRKTLGD LIPRHQHVFS TNQYFSGVKI 240

PDPEDMEPLE LKFPNISYSA LGLLKGCLHM NPAERLTCEQ LLQHSYFDSI REIGDSARQH 300

EKPTRKTLRQ SRKHLPGLQC LPQLTSSSIL PALDNKKHCY NTKKLNYHFP NI 352

Nucleotide Sequence
(FASTA)

ATGGAGAAGT ATGAAAAAAT TGGGAAAATT GGTGAAGGAT CCTATGGAGT TGTTTTCAAA 60

TGCCGAAACA GGGACACAGG TCAGATTGTG GCCATCAAGA AGTTTCTGGA ATCAGAAGAT 120

GACCCTGTCA TAAAGAAAAT CGCCCTTCGA GAAATCCGCA TGCTCAAGCA ACTCAAGCAT 180

CCCAATCTCG TCAACCTCAT CGAAGTCTTC AGGAGGAAGC GGAGGCTTCA CCTGGTGTTT 240

GAGTACTGTG ACCACACGGT GCTCCATGAG CTGGACAGAC ACCAAAGAGG GGTACCAGAA 300

CATCTTGTGA AGAGCATAAC TTGGCAGACA CTGCAGGCTG TAAATTTTTG CCATAAACAC 360

AGTTGCATAC ACAGGGATGT GAAGCCGGAA AACATCCTCG TCACGAAACA GTCTGTGATT 420

AAGCTTTGTG ACTTTGGATT CGCTCGACTT TTGACTGGAC CGAGCGACTA CTACACAGAC 480

TACGTGGCCA CCAGGTGGTA CCGCTCCCCA GAGCTGCTGG TGGGGGACAC GCAATACGGC 540

CCCCCGGTAG ATGTTTGGGC GATTGGCTGT GTCTTTGCTG AGCTGCTGTC AGGCGTTCCT 600

CTGTGGCCAG GAAAATCAGA TGTGGATCAG CTCTATCTGA TTAGGAAAAC CTTGGGAGAC 660

CTCATTCCTA GGCACCAACA TGTATTTAGC ACAAATCAGT ACTTCAGTGG GGTAAAAATT 720

CCAGACCCTG AAGATATGGA ACCACTTGAA TTAAAATTTC CAAACATCTC TTATTCTGCC 780

CTGGGCCTCT TAAAGGGCTG TCTCCACATG AATCCTGCCG AGAGACTGAC GTGTGAGCAG 840

CTGTTGCAGC ATTCGTATTT TGACAGTATC AGAGAAATAG GGGATTCGGC AAGACAGCAT 900

GAGAAACCAA CAAGGAAGAC CCTACGACAG AGCCGAAAGC ACTTGCCGGG GTTGCAGTGC 960

CTACCTCAGC TGACCAGCAG CAGCATCCTT CCAGCTCTGG ATAACAAGAA ACATTGCTAT 1020

AACACCAAGA AACTTAACTA CCATTTTCCA AACATTTAA 1059

Domain Profile

S: 1     yeklgkvGeGsyGvvlkcrnkdtgqivaikkfleseddkevkkialreikllkqlkhenl  60

         yek+gk+GeGsyGvv+kcrn+dtgqivaikkflesedd+++kkialrei++lkqlkh+nl

Q: 4     YEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKFLESEDDPVIKKIALREIRMLKQLKHPNL  63

         9***********************************************************

S: 61    vnllevfrrkkklylvfeyvdktvldelerypnGveeelvkkilyqilkaiefchknnii  120

         vnl+evfrrk++l+lvfey+d+tvl+el+r+++Gv+e+lvk+i++q+l+a++fchk+ +i

Q: 64    VNLIEVFRRKRRLHLVFEYCDHTVLHELDRHQRGVPEHLVKSITWQTLQAVNFCHKHSCI  123

         ************************************************************

S: 121   hrdikpenilisksgvvklcdfGfarllaapgdvytdyvatrwyrapellvgdtkyGksv  180

         hrd+kpenil++k++v+klcdfGfarll++p+d+ytdyvatrwyr+pellvgdt+yG++v

Q: 124   HRDVKPENILVTKQSVIKLCDFGFARLLTGPSDYYTDYVATRWYRSPELLVGDTQYGPPV  183

         ************************************************************

S: 181   dvwaiGcllaelltGeplfpgksdvdqlykirktlGeliprhqkifsknevfaGvklpev  240

         dvwaiGc++aell+G pl+pgksdvdqly+irktlG+liprhq++fs+n++f+Gvk+p++

Q: 184   DVWAIGCVFAELLSGVPLWPGKSDVDQLYLIRKTLGDLIPRHQHVFSTNQYFSGVKIPDP  243

         ************************************************************

S: 241   edleslekkypklnevlldllkkclkldpaerlsceellkheyf  284

         ed+e+le k+p++++++l llk+cl+++paerl+ce+ll+h+yf

Q: 244   EDMEPLELKFPNISYSALGLLKGCLHMNPAERLTCEQLLQHSYF  287

         *******************************************9

Domain Sequence
(FASTA)

YEKIGKIGEG SYGVVFKCRN RDTGQIVAIK KFLESEDDPV IKKIALREIR MLKQLKHPNL 60

VNLIEVFRRK RRLHLVFEYC DHTVLHELDR HQRGVPEHLV KSITWQTLQA VNFCHKHSCI 120

HRDVKPENIL VTKQSVIKLC DFGFARLLTG PSDYYTDYVA TRWYRSPELL VGDTQYGPPV 180

DVWAIGCVFA ELLSGVPLWP GKSDVDQLYL IRKTLGDLIP RHQHVFSTNQ YFSGVKIPDP 240

EDMEPLELKF PNISYSALGL LKGCLHMNPA ERLTCEQLLQ HSYF 284

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

bta:523900

;

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013