EKS-BOT-00205

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-BOT-00205

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/RCK	441.4	1.5E-132	19	300	282

Status

Unreviewed

Ensembl Protein

ENSBTAP00000009222

UniProt Accession

E1BDQ8;

Protein Name

Protein Synonyms/Alias

Gene Name

MOK

Gene Synonyms/Alias

MOK;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSBTAG00000007008	ENSBTAP00000009222	ENSBTAT00000009222

Organism

Bos taurus

Functional Description

Protein Length

433

Protein Sequence
(FASTA)

MLLLDYLTDE DICCLEADYK AIGKIGEGTF SEVMKIQNLR DGNHYACKQM KQRFESIEQV 60

NNLREIQALR RLNPHPNILT LHQVVFDRKS GSLALICELM DMNIYELIRG RRHPLSEKKV 120

RHYMYQLCKS LDHMHRNGIF HRDVKPENIL VKRDVLKLGD FGSCRSVYSK QPYTEYISTR 180

WYRAPECLLT DGFYGFKMDL WSAGCVLYEM ASLQPLFPGA NELDQISRIH DVMGTPAEKT 240

LTKFKQSRAM SFDFPFKKGS GIPLLTTSLS PQCLSLLHAM VAYDPDERIT AHQALQHPYF 300

QEQRAAEKQA LARARWKASA PFPECPTAPE LSSAWQTAQE GRKQKQPPRP EENHPRRPGP 360

ACLMELPRLK LSGAAKLASY SSPALPSVFL PKVPLLRPLK CVGAAQKTET QKDIKPSLKQ 420

YRLPTIERRG GGD 433

Nucleotide Sequence
(FASTA)

ATGTTGCTCT TGGATTATCT TACAGATGAA GACATCTGCT GTCTGGAAGC AGACTATAAA 60

GCAATTGGCA AAATAGGAGA GGGAACGTTT TCTGAAGTTA TGAAGATACA GAACCTGAGA 120

GATGGCAACC ACTACGCATG TAAACAGATG AAACAGCGCT TTGAAAGCAT CGAGCAAGTG 180

AACAACCTGC GAGAGATACA AGCGCTGAGG CGCCTGAACC CACACCCGAA CATCCTCACG 240

CTGCACCAGG TGGTCTTTGA CAGAAAATCT GGTTCTCTTG CACTAATATG TGAACTTATG 300

GACATGAATA TTTATGAGCT AATACGAGGA AGAAGACACC CGTTATCAGA GAAAAAAGTT 360

AGGCACTATA TGTACCAGCT GTGTAAGTCC CTGGACCACA TGCACAGAAA TGGAATATTT 420

CACAGAGATG TAAAACCAGA AAATATATTA GTAAAGCGGG ATGTCCTGAA GCTTGGGGAC 480

TTCGGGTCGT GCCGGAGCGT CTACTCGAAG CAGCCGTACA CCGAGTACAT CTCCACCCGC 540

TGGTACCGGG CCCCTGAGTG CCTCCTCACT GATGGCTTCT ACGGCTTCAA GATGGACCTG 600

TGGAGCGCGG GCTGCGTGCT CTACGAGATG GCCAGCCTGC AGCCGCTCTT CCCCGGAGCC 660

AACGAGCTGG ACCAGATCTC TAGGATCCAC GACGTCATGG GCACGCCTGC TGAGAAGACT 720

CTCACCAAGT TCAAGCAGTC GAGAGCTATG AGTTTTGATT TTCCTTTTAA AAAGGGATCA 780

GGGATACCTC TACTGACCAC CAGTCTGTCC CCGCAATGCC TCTCCCTTCT GCACGCCATG 840

GTGGCCTATG ATCCCGATGA GAGAATCACT GCCCACCAGG CCCTGCAACA CCCTTACTTC 900

CAGGAGCAGA GGGCGGCTGA GAAGCAGGCG CTGGCCAGGG CCAGGTGGAA GGCCTCCGCT 960

CCCTTCCCCG AGTGCCCCAC GGCCCCAGAG CTCAGCAGCG CCTGGCAGAC GGCGCAGGAG 1020

GGCCGGAAGC AGAAACAGCC CCCGAGGCCA GAGGAGAACC ACCCCCGGAG GCCGGGGCCG 1080

GCTTGCCTGA TGGAGCTGCC CAGGCTGAAG CTGTCGGGAG CGGCCAAGCT GGCCTCCTAC 1140

TCCAGCCCGG CCCTGCCATC CGTGTTCCTC CCGAAGGTGC CGCTGCTGAG ACCCCTGAAG 1200

TGCGTCGGTG CGGCCCAGAA GACAGAGACG CAGAAGGACA TCAAGCCCAG CCTGAAGCAG 1260

TACCGCCTGC CCACGATAGA GCGCAGAGGT GGGGGCGACT GA 1302

Domain Profile

S: 1     yklikklGdGtfgevllakslktgelvaikkmkrkfesleevtnlrevkslkklnahdni  60

         yk+i k+G+Gtf+ev++ ++l++g+ +a+k+mk++fes+e+v+nlre+++l++ln+h+ni

Q: 19    YKAIGKIGEGTFSEVMKIQNLRDGNHYACKQMKQRFESIEQVNNLREIQALRRLNPHPNI  78

         99**********************************************************

S: 61    iklkeviidrendslylvlelmeenlyqlikdrrkllsesklksilyqilkglafihkhg  120

         ++l++v++dr+++sl+l++elm++n+y+li++rr+ lse+k+++++yq++k+l+++h++g

Q: 79    LTLHQVVFDRKSGSLALICELMDMNIYELIRGRRHPLSEKKVRHYMYQLCKSLDHMHRNG  138

         ************************************************************

S: 121   ffhrdlkPenilikgselvkladfGlarevrsknPytdyvstrwyraPevllrsgvyssp  180

         +fhrd+kPenil+k  +++kl+dfG++r+v+sk+Pyt+y+strwyraPe+ll++g+y  +

Q: 139   IFHRDVKPENILVK-RDVLKLGDFGSCRSVYSKQPYTEYISTRWYRAPECLLTDGFYGFK  197

         **************.9********************************************

S: 181   ldlwavGcvlaevavlrplfPGaseidqifkilevlGtPkkkewdeayklasalnlkfpq  240

         +dlw++Gcvl+e+a+l+plfPGa+e+dqi++i++v+GtP++k++++ +k+++a++++fp+

Q: 198   MDLWSAGCVLYEMASLQPLFPGANELDQISRIHDVMGTPAEKTLTK-FKQSRAMSFDFPF  256

         *********************************************9.*************

S: 241   vegsslktlvsnaskealellkdllaydPderataqqalkypyf  284

         ++gs+++ l++++s ++l+ll++++aydPder+ta+qal++pyf

Q: 257   KKGSGIPLLTTSLSPQCLSLLHAMVAYDPDERITAHQALQHPYF  300

         *******************************************9

Domain Sequence
(FASTA)

YKAIGKIGEG TFSEVMKIQN LRDGNHYACK QMKQRFESIE QVNNLREIQA LRRLNPHPNI 60

LTLHQVVFDR KSGSLALICE LMDMNIYELI RGRRHPLSEK KVRHYMYQLC KSLDHMHRNG 120

IFHRDVKPEN ILVKRDVLKL GDFGSCRSVY SKQPYTEYIS TRWYRAPECL LTDGFYGFKM 180

DLWSAGCVLY EMASLQPLFP GANELDQISR IHDVMGTPAE KTLTKFKQSR AMSFDFPFKK 240

GSGIPLLTTS LSPQCLSLLH AMVAYDPDER ITAHQALQHP YF 282

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Dasypus novemcinctus"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

bta:616277

;

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013