EKS-BOT-00018

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-BOT-00018

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/PHK	525.4	3.1E-158	20	288	269

Status

Unreviewed

Ensembl Protein

ENSBTAP00000010780

UniProt Accession

Q29RI2; F1MEQ8;

Protein Name

Protein Synonyms/Alias

Phosphorylase kinase, gamma 1 (Muscle);

Gene Name

PHKG1

Gene Synonyms/Alias

PHKG1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSBTAG00000008195	ENSBTAP00000010780	ENSBTAT00000010780

Organism

Bos taurus

Functional Description

Protein Length

387

Protein Sequence
(FASTA)

MTQDKSLPDS SSAQSFYENY EPKEILGRGV SSVVRRCIHK PTCQEYAVKI IDITGGGSFS 60

SEEVQELREA TQKEVDILRK VSGHPNIIQL KDTYETNTFF FLVFDLMKRG ELFDYLTEKV 120

TLSEKETRKI MRALLEVIAT LHRLNIVHRD LKPENILLDD NMNIKLTDFG FSCQLEPGEK 180

LREVCGTPSY LAPEIIECSM NDDHPGYGKE VDMWSTGVIM YTLLAGSPPF WHRKQMLMLR 240

MIMSGNYQFG SPEWDDYSDT VKDLVSRFLV VSPQRRCSAE EALAHPFFQQ YVVEEVRHFS 300

PRGKFKVICL TVLASVRIYY QYRRVKPVTR EIVIRDPYAL RPLRRLIDAY AFRIYGHWVK 360

KGQQQNRAAL FENTPKAVLL SLAEEDF 387

Nucleotide Sequence
(FASTA)

ATGACCCAGG ACAAGTCGCT GCCGGACTCC TCTTCTGCAC AGAGCTTCTA TGAGAACTAT 60

GAGCCCAAGG AGATCCTGGG CAGGGGAGTG AGCAGCGTCG TCAGGCGCTG CATCCACAAG 120

CCCACGTGCC AGGAGTACGC TGTGAAGATC ATCGACATCA CCGGCGGGGG CAGCTTCAGC 180

TCCGAGGAGG TGCAGGAGCT GCGAGAGGCC ACGCAGAAGG AGGTGGACAT CCTGCGCAAG 240

GTCTCGGGAC ACCCCAACAT CATACAGCTG AAGGACACTT ATGAGACCAA CACCTTCTTC 300

TTCTTGGTGT TTGATCTGAT GAAGAGAGGG GAGCTCTTTG ACTACCTCAC TGAGAAGGTC 360

ACCCTGAGTG AGAAAGAGAC CAGGAAGATC ATGAGAGCCC TGCTGGAGGT GATCGCCACC 420

TTGCACAGAC TCAACATCGT GCATCGGGAT CTGAAGCCTG AGAACATCCT CCTGGACGAT 480

AACATGAACA TCAAGCTTAC AGACTTCGGC TTTTCCTGCC AGCTGGAGCC AGGAGAGAAG 540

CTGCGAGAGG TCTGTGGGAC CCCCAGTTAC CTGGCCCCTG AGATCATCGA GTGCTCCATG 600

AACGATGACC ACCCCGGCTA TGGGAAGGAG GTGGACATGT GGAGCACGGG GGTCATCATG 660

TACACGCTGC TGGCCGGCTC CCCGCCCTTC TGGCACCGCA AGCAGATGCT GATGTTGAGA 720

ATGATCATGA GTGGCAACTA CCAGTTTGGC TCACCGGAAT GGGATGATTA CTCGGACACC 780

GTGAAGGACT TGGTTTCCCG CTTCTTGGTG GTGAGCCCCC AGAGGCGCTG CTCGGCAGAA 840

GAGGCCTTGG CGCACCCCTT CTTCCAGCAG TACGTGGTGG AGGAAGTGCG TCACTTCAGC 900

CCCCGGGGCA AGTTCAAGGT GATCTGCCTG ACGGTGCTGG CTTCAGTGCG CATTTACTAC 960

CAGTACCGCC GGGTGAAGCC CGTGACCCGG GAGATTGTCA TTCGAGACCC CTACGCCCTC 1020

CGGCCTCTGC GGCGACTCAT CGACGCCTAC GCTTTCCGGA TCTATGGTCA CTGGGTGAAG 1080

AAGGGGCAGC AGCAGAACCG GGCGGCCCTC TTCGAGAACA CGCCCAAGGC CGTGCTCCTC 1140

TCCCTGGCTG AGGAGGACTT CTGA 1164

Domain Profile

S: 1     yepkeilGrGvssvvrrciekatgqefavkiidvs.aeklseeevkelreatlkeveilr  59

         yepkeilGrGvssvvrrci+k+t+qe+avkiid++ ++++s+eev+elreat+kev+ilr

Q: 20    YEPKEILGRGVSSVVRRCIHKPTCQEYAVKIIDITgGGSFSSEEVQELREATQKEVDILR  79

         9**********************************899**********************

S: 60    qvsGhpsiiklkdvyesssflflvfdlmkkGelfdyltekvtlseketrkimralleave  119

         +vsGhp+ii+lkd+ye+++f+flvfdlmk+Gelfdyltekvtlseketrkimralle+++

Q: 80    KVSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLSEKETRKIMRALLEVIA  139

         ************************************************************

S: 120   ylhaknivhrdlkpenillddneniklsdfGfstqleeGeklrelcGtpgylapeilkcs  179

         +lh+ nivhrdlkpenillddn+nikl+dfGfs+qle+Geklre+cGtp+ylapei++cs

Q: 140   TLHRLNIVHRDLKPENILLDDNMNIKLTDFGFSCQLEPGEKLREVCGTPSYLAPEIIECS  199

         ************************************************************

S: 180   mdeeapGyskevdlwalGvilytllaGsppfwhrkqllmlrlimeGkyqftspewddise  239

         m++++pGy+kevd+w++Gvi+ytllaGsppfwhrkq+lmlr+im+G+yqf+spewdd+s+

Q: 200   MNDDHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMSGNYQFGSPEWDDYSD  259

         ************************************************************

S: 240   evkdliskllvvdpekrltaeealahpff  268

         +vkdl+s++lvv p++r++aeealahpff

Q: 260   TVKDLVSRFLVVSPQRRCSAEEALAHPFF  288

         ****************************8

Domain Sequence
(FASTA)

YEPKEILGRG VSSVVRRCIH KPTCQEYAVK IIDITGGGSF SSEEVQELRE ATQKEVDILR 60

KVSGHPNIIQ LKDTYETNTF FFLVFDLMKR GELFDYLTEK VTLSEKETRK IMRALLEVIA 120

TLHRLNIVHR DLKPENILLD DNMNIKLTDF GFSCQLEPGE KLREVCGTPS YLAPEIIECS 180

MNDDHPGYGK EVDMWSTGVI MYTLLAGSPP FWHRKQMLML RMIMSGNYQF GSPEWDDYSD 240

TVKDLVSRFL VVSPQRRCSA EEALAHPFF 269

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005964	; C:phosphorylase kinase complex
GO:0005524	; F:ATP binding
GO:0004689	; F:phosphorylase kinase activity
GO:0005978	; P:glycogen biosynthetic process

KEGG

bta:540682

;

InterPros

IPR020636	; Ca/CaM-dep_Ca-dep_prot_Kinase.
IPR011009	; Kinase-like_dom.
IPR002291	; Phosph_kin_gamma.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

PR01049

; PHOSPHBKNASE.

Created Date

20-Feb-2013