| Tag | Content |
|---|
| EKPD ID | EPS-BOT-00070 |
| Classification | | Group/Family | Score | E-Value | Start | End | Domain Length |
|---|
| Asp-Based PTP/FCP | 101.7 | 4.4E-29 | 138 | 300 | 163 |
|
| Status | Reviewed |
| Ensembl Protein | ENSBTAP00000011999 |
| UniProt Accession | Q2KJD7; |
| Protein Name | Ubiquitin-like domain-containing CTD phosphatase 1 |
| Protein Synonyms/Alias | Nuclear proteasome inhibitor UBLCP1; |
| Gene Name | UBLCP1 |
| Gene Synonyms/Alias | UBLCP1; |
| Ensembl Information | |
| Organism | Bos taurus |
| Functional Description | Dephosphorylates 26S nuclear proteasomes, therebydecreasing their proteolytic activity. The dephosphorylation may prevent assembly of the core and regulatory particles (CP and RP) into mature 26S proteasome (By similarity). |
| Protein Length | 318 |
Protein Sequence
(FASTA) | | MALPIIVKWG GQEYSVTTLS EDDTVLDLKQ FLKTLTGVLP ERQKLLGLKV KGKPAENDVK 60 | | LGALKLKPNT KIMMMGTREE SLEDVLGPPP DNDDVVNDFD IEDEVVEVEN REENLLKISR 120 | | RVKEYKVEIL NPPREGKKLL VLDVDYTLFD HRSCAETGVE LMRPYLHEFL TSAYEDYDIV 180 | | IWSATNMKWI EAKMKELGVS TNANYKITFM LDSAAMITVH TPRRGLIDVK PLGVIWGKFS 240 | | EFYSKKNTIM FDDIGRNFLM NPQNGLKIRP FMKAHLNRDK DKELLKLTQY LKEIAKLDDF 300 | | LDLNHKYWER YLSKKQGQ 318 |
|
Nucleotide Sequence
(FASTA) | | ATGGCTCTTC CTATCATTGT AAAATGGGGT GGACAGGAAT ATTCAGTGAC CACACTTTCG 60 | | GAAGATGATA CTGTGCTGGA TCTCAAACAG TTTCTGAAGA CCCTTACAGG AGTGCTACCA 120 | | GAACGCCAGA AGTTACTTGG GCTCAAAGTT AAAGGCAAAC CTGCAGAAAA TGATGTTAAG 180 | | CTTGGAGCTC TCAAACTGAA ACCAAATACT AAAATCATGA TGATGGGAAC TCGTGAGGAG 240 | | AGCTTGGAAG ATGTCTTAGG TCCACCTCCT GACAATGATG ACGTTGTTAA CGACTTTGAT 300 | | ATTGAAGATG AAGTAGTTGA AGTAGAAAAT AGGGAGGAAA ACCTACTGAA AATTTCCCGC 360 | | AGAGTAAAAG AGTACAAAGT GGAAATTTTG AATCCTCCCA GGGAAGGGAA AAAACTTTTG 420 | | GTACTAGATG TTGATTATAC ATTATTTGAC CATAGGTCTT GTGCAGAGAC TGGGGTAGAA 480 | | TTAATGCGGC CATATCTTCA TGAATTCCTA ACATCTGCAT ATGAGGATTA TGACATTGTT 540 | | ATTTGGTCTG CAACAAATAT GAAGTGGATT GAAGCTAAAA TGAAAGAGCT GGGAGTGAGT 600 | | ACAAATGCAA ATTACAAGAT TACCTTCATG TTGGACAGTG CTGCTATGAT AACAGTGCAT 660 | | ACTCCGAGGA GAGGATTAAT AGATGTAAAG CCTCTTGGTG TTATATGGGG AAAGTTTTCG 720 | | GAGTTTTACA GCAAGAAAAA CACCATCATG TTTGATGACA TAGGAAGAAA TTTTCTAATG 780 | | AACCCACAGA ATGGACTAAA GATAAGACCT TTTATGAAAG CACACCTAAA TCGAGATAAA 840 | | GACAAAGAAC TTTTAAAATT AACCCAATAC CTCAAGGAAA TAGCAAAACT AGATGATTTT 900 | | TTGGACCTGA ATCACAAATA CTGGGAAAGG TATCTCTCAA AGAAGCAAGG ACAGTAG 957 |
|
| Domain Profile | S: 1 ktLVLDLDetLvhsksekdeeeektkasvkkRPgldeFLkelskayevviftasskeyad 60 | k+LVLD+D+tL++++s ++ t +++ +RP+l+eFL+++ ++y++vi++a+++++++ | Q: 138 KLLVLDVDYTLFDHRSCAE-----TGVEL-MRPYLHEFLTSAYEDYDIVIWSATNMKWIE 191 | 79*************5443.....45555.7***************************** |
| S: 61 avldkld......pkkklf....kkrlyresctlengky.vKdLsll........grdls 101 | a +++l + k f ++++ ++ ++g + vK L ++ + + | Q: 192 AKMKELGvstnanY-KITFmldsAAMITV-HT-PRRGLIdVKPLGVIwgkfsefyS--KK 246 | *******5543321.22223554444444.34.78887768******999876543..69 |
| S: 102 kvvivDdsprsfelqpdnlipiepfygds...dkdtellkllpflealeksddv 152 | +++++Dd r+f ++p+n+++i+pf++++ dkd+ellkl+++l++++k dd+ | Q: 247 NTIMFDDIGRNFLMNPQNGLKIRPFMKAHlnrDKDKELLKLTQYLKEIAKLDDF 300 | *******************************999**************987886 |
|
Domain Sequence
(FASTA) | | KLLVLDVDYT LFDHRSCAET GVELMRPYLH EFLTSAYEDY DIVIWSATNM KWIEAKMKEL 60 | | GVSTNANYKI TFMLDSAAMI TVHTPRRGLI DVKPLGVIWG KFSEFYSKKN TIMFDDIGRN 120 | | FLMNPQNGLK IRPFMKAHLN RDKDKELLKL TQYLKEIAKL DDF 163 |
|
| Keyword | Acetylation; Complete proteome; Hydrolase; Nucleus; Protein phosphatase; Reference proteome. |
| Sequence Source | Ensembl |
| Orthology | |
| Gene Ontology | |
| KEGG | |
| InterPros | |
| Pfam | |
| SMARTs | |
| Prosites | |
| Prints | |
| Created Date | 20-Feb-2013 |