EKS-BOT-00143

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-BOT-00143

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Atypical/RIO	325.9	1.4E-97	252	480	229

Status

Reviewed

Ensembl Protein

ENSBTAP00000013242

UniProt Accession

Q1RMT7;

Protein Name

Serine/threonine-protein kinase RIO3

Protein Synonyms/Alias

RIO kinase 3;

Gene Name

RIOK3

Gene Synonyms/Alias

RIOK3;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSBTAG00000010042	ENSBTAP00000013242	ENSBTAT00000013242

Organism

Bos taurus

Functional Description

Protein Length

519

Protein Sequence
(FASTA)

MDLVRVASPE PGPAAAWGPN KCPWATPQNT ISCSLSDVMS EQLAKELQLE EEAAAFPEVT 60

VAEGPFITGE NIDTSSDLML AQMLQMEFDR EYDAQLRREE KKFNGDSKVC ISFENYRKVH 120

PYEDSDSSED EVDWQDTRDD PYRPAKPIPT PKKGFIGKGK DITTKHDEVV CGRKNTARME 180

NFAPGFQVGD GIGMDLKLSN HVFNALKQHA YSEERRSARL HEKKEHSTAE KAVDPKTRLL 240

MYKMVNSGML ETITGCISTG KESVVFHAYG GSMEDGKEDS KVIPTECAIK VFKTTLNEFK 300

NRDKYIKDDF RFKDRFSKLN PRKIIRMWAE KEMHNLTRMQ RAGIPCPTVV LLKKHILVMS 360

FIGHDQVPAP KLKEVKLSSE EMKDAYYQTL HLMQQLYDEC TLVHADLSEY NMLWHAGKVW 420

LIDVSQSVEP THPHGLEFLF RDCRNVSQFF QKGGVKEALG ERELFNAVSG LNISADNEAD 480

FLAEIEALEK MNEDHVQKNG RKAASFLKDD GGPPILYDE 519

Nucleotide Sequence
(FASTA)

ATGGATCTGG TCAGAGTGGC ATCCCCTGAG CCCGGGCCAG CAGCGGCCTG GGGACCCAAC 60

AAGTGTCCAT GGGCTACCCC TCAAAATACA ATATCTTGTT CTTTGTCTGA TGTAATGAGT 120

GAGCAGTTGG CTAAAGAATT GCAATTAGAA GAAGAAGCTG CCGCTTTTCC TGAAGTTACT 180

GTTGCTGAAG GACCATTTAT TACTGGAGAA AACATTGACA CTTCCAGCGA CCTAATGCTG 240

GCTCAGATGC TACAGATGGA GTTTGACAGA GAATATGATG CCCAGCTTAG GCGTGAAGAA 300

AAAAAATTCA ATGGAGATAG CAAAGTTTGC ATTTCCTTTG AAAATTATCG AAAAGTGCAT 360

CCTTACGAAG ACAGTGATAG CTCTGAAGAT GAGGTTGACT GGCAGGACAC TCGTGATGAC 420

CCCTACAGAC CAGCAAAACC AATTCCTACT CCCAAAAAGG GTTTTATTGG AAAAGGAAAA 480

GACATCACCA CCAAACACGA TGAAGTAGTA TGTGGGAGAA AGAACACAGC CAGAATGGAA 540

AATTTTGCAC CTGGGTTTCA GGTAGGAGAT GGAATTGGAA TGGACTTAAA ACTATCAAAC 600

CATGTTTTCA ATGCTTTAAA ACAGCATGCC TACTCAGAAG AACGTCGAAG TGCCCGCCTC 660

CATGAGAAAA AGGAGCATTC CACTGCAGAA AAAGCAGTTG ATCCTAAGAC ACGTTTACTT 720

ATGTATAAAA TGGTCAACTC TGGAATGTTG GAGACAATCA CTGGCTGTAT TAGTACAGGA 780

AAGGAATCTG TTGTCTTTCA TGCATATGGA GGGAGCATGG AGGATGGAAA GGAAGATAGT 840

AAAGTTATAC CTACAGAATG TGCCATCAAG GTATTTAAAA CAACCCTTAA TGAGTTTAAG 900

AATCGTGACA AATATATTAA AGATGATTTC AGGTTTAAAG ATCGCTTCAG TAAACTAAAT 960

CCGCGTAAGA TCATCCGCAT GTGGGCAGAA AAAGAAATGC ACAATCTTAC AAGGATGCAG 1020

AGAGCTGGAA TTCCTTGTCC AACAGTTGTA CTACTCAAGA AACACATTTT AGTTATGTCT 1080

TTTATTGGCC ATGATCAAGT TCCAGCCCCT AAATTGAAAG AAGTAAAGCT CAGCAGTGAA 1140

GAAATGAAAG ACGCCTACTA TCAAACTCTT CATTTGATGC AGCAGTTATA TGACGAATGT 1200

ACGCTCGTAC ACGCCGACCT CAGTGAGTAC AACATGCTCT GGCATGCTGG GAAGGTCTGG 1260

TTGATCGATG TCAGTCAGTC TGTAGAACCA ACCCACCCTC ATGGCCTGGA GTTCTTGTTT 1320

CGTGACTGTA GGAATGTCTC ACAGTTTTTT CAGAAAGGAG GAGTAAAGGA AGCCCTTGGT 1380

GAACGAGAAC TCTTCAATGC TGTTTCAGGC TTAAACATCT CGGCAGATAA TGAAGCTGAT 1440

TTCTTAGCTG AGATAGAAGC TTTGGAGAAA ATGAATGAAG ATCATGTTCA GAAGAATGGA 1500

AGGAAAGCTG CTTCATTTTT GAAAGATGAT GGAGGTCCAC CAATCTTATA TGATGAATAG 1560

Domain Profile

S: 2     svgntigvgkesdvykvsekngee...........raiKiyktsllvlknrdkYvdgefr  50

         +++++i++gkes v++++  ++e+           +aiK++kt+l+++knrdkY++++fr

Q: 252   TITGCISTGKESVVFHAYGGSMEDgkedskvipteCAIKVFKTTLNEFKNRDKYIKDDFR  311

         79********************99999*********************************

S: 51    fkksrskanprklsrlwAeKEfrnlkrlyekgvpvPepidlkrhvlvmeligrdgypapk  110

         fk+++sk nprk++r+wAeKE++nl+r++++g+p+P+++ lk+h+lvm++ig+d++papk

Q: 312   FKDRFSKLNPRKIIRMWAEKEMHNLTRMQRAGIPCPTVVLLKKHILVMSFIGHDQVPAPK  371

         ************************************************************

S: 111   lkdvklkeeeikelYsdllalivklynegrLvHaDlsEfnilleddklvliDvsqsveie  170

         lk+vkl++ee+k++Y+++l+l+++ly+e++LvHaDlsE+n+l++++k++liDvsqsve++

Q: 372   LKEVKLSSEEMKDAYYQTLHLMQQLYDECTLVHADLSEYNMLWHAGKVWLIDVSQSVEPT  431

         ************************************************************

S: 171   HpdaleflrrDvknvkefFkkklvydvlrerelfelvsasgltkekead  219

         Hp++lefl rD++nv++fF+k +v+++l erelf++vs+ ++++++ead

Q: 432   HPHGLEFLFRDCRNVSQFFQKGGVKEALGERELFNAVSGLNISADNEAD  480

         **********************************************996

Domain Sequence
(FASTA)

TITGCISTGK ESVVFHAYGG SMEDGKEDSK VIPTECAIKV FKTTLNEFKN RDKYIKDDFR 60

FKDRFSKLNP RKIIRMWAEK EMHNLTRMQR AGIPCPTVVL LKKHILVMSF IGHDQVPAPK 120

LKEVKLSSEE MKDAYYQTLH LMQQLYDECT LVHADLSEYN MLWHAGKVWL IDVSQSVEPT 180

HPHGLEFLFR DCRNVSQFFQ KGGVKEALGE RELFNAVSGL NISADNEAD 229

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Phosphoprotein; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macropus eugenii"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>