| Tag | Content |
|---|
| EKPD ID | EPS-BOT-00009 |
| Classification | | Group/Family | Score | E-Value | Start | End | Domain Length |
|---|
| DSP/aDSP | 149.2 | 7.7E-44 | 27 | 165 | 139 |
|
| Status | Reviewed |
| Ensembl Protein | ENSBTAP00000013570 |
| UniProt Accession | Q17QM8; |
| Protein Name | Dual specificity protein phosphatase 14 |
| Protein Synonyms/Alias | |
| Gene Name | DUSP14 |
| Gene Synonyms/Alias | DUSP14; |
| Ensembl Information | |
| Organism | Bos taurus |
| Functional Description | Involved in the inactivation of MAP kinases.Dephosphorylates ERK, JNK and p38 MAP-kinases (By similarity). |
| Protein Length | 198 |
Protein Sequence
(FASTA) | | MSSRGHSTLP RTLMAPRMIS EGDLGGIAQI TSSLFLGRGS VASNRHLLQA RGITCIVNAT 60 | | IEIPNFNWPQ FEYVKVPLAD MPHAPIGLYF DTVADKIHSV SRKHGATLVH CAAGVSRSAT 120 | | LCIAYLMKFH NVCLLEAYNW VKARRPVIRP NVGFWRQLID YERQLFGKST VKMVQTPYGI 180 | | VPDVYEKESR HLLPYWGI 198 |
|
Nucleotide Sequence
(FASTA) | | ATGAGCTCCA GAGGTCACAG CACGCTCCCC CGGACTCTCA TGGCCCCCCG GATGATTTCT 60 | | GAGGGAGACC TGGGAGGCAT TGCGCAGATC ACCTCCTCGC TCTTCCTGGG CAGAGGCAGC 120 | | GTAGCCTCCA ACCGGCACCT CCTCCAGGCT CGCGGCATCA CCTGCATTGT GAACGCTACC 180 | | ATCGAGATCC CCAATTTCAA CTGGCCCCAG TTTGAATACG TTAAAGTGCC TCTGGCGGAC 240 | | ATGCCTCACG CCCCCATTGG ACTGTACTTT GACACCGTGG CCGACAAGAT CCACAGCGTG 300 | | AGCCGGAAAC ACGGGGCCAC CCTGGTGCAC TGTGCTGCGG GGGTCAGCCG CTCGGCCACG 360 | | CTCTGCATCG CGTACCTGAT GAAATTCCAC AACGTGTGCC TGCTGGAGGC CTACAACTGG 420 | | GTGAAAGCCC GGAGGCCCGT CATCAGGCCC AACGTCGGCT TCTGGAGGCA GCTGATAGAC 480 | | TACGAGCGGC AGCTTTTTGG GAAGTCGACA GTTAAGATGG TACAGACACC GTACGGCATA 540 | | GTGCCGGACG TTTACGAGAA GGAGTCCCGA CACCTGCTGC CTTACTGGGG GATCTGA 597 |
|
| Domain Profile | S: 2 vteilpglylgdqataldrreLsklgitvvinaslsvikvqviPeylikkgityknipvd 61 | + +i+++l+lg +a +r L++ git ++na++++ ++ + +y+++p | Q: 27 IAQITSSLFLGRGSVASNRHLLQARGITCIVNATIEIPNF-------NWPQFEYVKVPLA 79 | 789*******************************999993.......356778******* |
| S: 62 DsdvtdllqyfdeaaefideakekggkvlvHCaaGvsRSatlvlaYLmkveglslsdAie 121 | D ++ + yfd++a+ i+++++k+g++lvHCaaGvsRSatl++aYLmk++++ l +A++ | Q: 80 DMPHAPIGLYFDTVADKIHSVSRKHGATLVHCAAGVSRSATLCIAYLMKFHNVCLLEAYN 139 | ************************************************************ |
| S: 122 avkrkrpsiepnegfleQLlelekkl 147 | +vk++rp i+pn gf++QL+ +e++l | Q: 140 WVKARRPVIRPNVGFWRQLIDYERQL 165 | ************************98 |
|
Domain Sequence
(FASTA) | | IAQITSSLFL GRGSVASNRH LLQARGITCI VNATIEIPNF NWPQFEYVKV PLADMPHAPI 60 | | GLYFDTVADK IHSVSRKHGA TLVHCAAGVS RSATLCIAYL MKFHNVCLLE AYNWVKARRP 120 | | VIRPNVGFWR QLIDYERQL 139 |
|
| Keyword | Complete proteome; Hydrolase; Phosphoprotein; Protein phosphatase; Reference proteome. |
| Sequence Source | Ensembl |
| Orthology | |
| Gene Ontology | | GO:0017017 | ; F:MAP kinase tyrosine/serine/threonine phosphatase activity | | GO:0004725 | ; F:protein tyrosine phosphatase activity | | GO:0008138 | ; F:protein tyrosine/serine/threonine phosphatase activity | | GO:0035335 | ; P:peptidyl-tyrosine dephosphorylation |
|
| KEGG | |
| InterPros | |
| Pfam | |
| SMARTs | |
| Prosites | |
| Prints | |
| Created Date | 20-Feb-2013 |