EKS-BOT-00063

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-BOT-00063

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDK	377.7	3.5E-113	414	699	286

Status

Unreviewed

Ensembl Protein

ENSBTAP00000014227

UniProt Accession

F1N5K1;

Protein Name

Protein Synonyms/Alias

Gene Name

CDC2L1

Gene Synonyms/Alias

CDC2L1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSBTAG00000010737	ENSBTAP00000041178	ENSBTAT00000043619
ENSBTAG00000010737	ENSBTAP00000014227	ENSBTAT00000014227

Organism

Bos taurus

Functional Description

Protein Length

771

Protein Sequence
(FASTA)

MGDEKDSWKV KTLDEILQEK KRRKEQEEKA EIKRLKNSDD RDSKRDSLEE GELRDHRMEI 60

TIRNSPYRRE DSMEDRGEED DSLAIKPPQQ MSRKEKAHHR KDEKRKEKRK HARVKEKERE 120

HERRKRHREE QDKARREWER QKRRELAREH SRRERDRLEQ LERKRERERK MREQQKEQRE 180

QKERERRAEE RRKEREARRE VSAHHRTVRE DYSDKVKASH WSRSPLRPPR ERLEPGDSRK 240

PVKEEKVEER DLLSDLQDVS DSERKTSSAE SSSAESGSGS EEEEEEEEEE EGSSSEESEE 300

EEEEEEEEEE EETGSNSEDV SGQSAEEVSE EEMSEDEERE NENHVLVVPE SRFDHDSGES 360

EEGEEEAGEG TPQSSALTEG DFVPDSPALS PIELKQELPK YLPALQGCRS VEEFQCLNRI 420

EEGTYGVVYR AKDKKTDEIV ALKRLKMEKE KEGFPITSLR EINTILKAQH PNIVTVREIV 480

VGSNMDKIYI VMNYVEHDLK SLMETMKQPF LPGEVKTLMI QLLRGVKHLH DNWILHRDLK 540

TSNLLLSHAG ILKVGDFGLA REYGSPLKAY TPVVVTLWYR APELLLGAKE YSTAVDMWSV 600

GCIFGELLTQ KPLFPGKSEI DQINKVFKDL GTPSEKIWPG YNDLPAVKKM TFTEYPYNNL 660

RKRFGALLSD QGFDLMNKFL TYFPGRRVNA EDGLKHEYFR ETPLPIDPSM FPTWPAKSEQ 720

QRVKRGTSPR PPEGGLGYSQ LGDDDLKETG FHLTTTNQGA SAAGPGFSLK F 771

Nucleotide Sequence
(FASTA)

ATGGGTGATG AAAAGGACTC TTGGAAAGTG AAAACTTTAG ATGAAATTCT TCAGGAAAAG 60

AAACGACGGA AGGAACAAGA GGAGAAAGCA GAGATAAAAC GCTTAAAAAA TTCTGATGAC 120

CGGGATTCCA AGCGGGATTC CCTTGAGGAG GGGGAGCTGA GGGACCACCG CATGGAGATA 180

ACAATAAGGA ACTCGCCGTA CAGAAGAGAG GACTCCATGG AAGACAGAGG AGAGGAAGAT 240

GATTCTTTGG CTATCAAACC ACCCCAGCAG ATGTCTCGGA AGGAAAAAGC ACATCACAGG 300

AAAGACGAAA AGAGAAAAGA GAAACGGAAG CACGCCAGAG TGAAAGAGAA GGAGCGGGAG 360

CATGAGCGCC GGAAGCGGCA CCGGGAGGAG CAGGACAAGG CTCGGAGGGA GTGGGAGCGG 420

CAGAAGCGGA GGGAGCTGGC CCGGGAGCAC TCGCGCAGGG AGAGGGACCG CCTCGAGCAG 480

TTAGAGAGGA AGCGAGAACG GGAACGCAAG ATGCGGGAAC AGCAGAAGGA GCAGCGGGAG 540

CAGAAGGAGC GGGAGCGGCG GGCCGAGGAG AGGCGCAAGG AGCGGGAGGC CCGGCGGGAA 600

GTGTCTGCAC ATCACCGGAC CGTGAGAGAG GACTACAGCG ATAAGGTGAA AGCCAGCCAC 660

TGGAGCCGTA GCCCACTCCG GCCTCCTCGA GAAAGGCTTG AGCCGGGGGA CAGCCGGAAG 720

CCAGTGAAAG AAGAGAAAGT GGAAGAGAGA GACCTGCTGT CCGACCTGCA GGACGTCAGC 780

GACAGCGAGA GGAAGACCAG CTCCGCTGAG TCCTCGTCAG CGGAGTCGGG GTCAGGTTCT 840

GAGGAGGAGG AAGAGGAGGA GGAGGAGGAA GAGGGGAGCA GCAGTGAGGA GTCAGAGGAG 900

GAAGAGGAGG AAGAGGAAGA AGAGGAGGAG GAGGAGACTG GAAGCAACTC TGAGGATGTG 960

TCTGGACAAT CAGCCGAAGA AGTGAGTGAA GAAGAAATGA GTGAAGATGA GGAGCGAGAG 1020

AATGAGAACC ACGTCTTGGT TGTTCCAGAG TCACGGTTTG ACCACGATTC TGGAGAGAGT 1080

GAAGAGGGGG AAGAGGAGGC AGGTGAGGGC ACCCCCCAGA GCAGCGCCCT CACCGAAGGG 1140

GACTTTGTGC CTGACTCTCC AGCCCTGTCA CCCATCGAGC TCAAGCAGGA GCTGCCCAAG 1200

TACCTGCCCG CCCTGCAGGG CTGTCGGAGT GTGGAGGAGT TCCAGTGTCT GAACAGGATT 1260

GAGGAAGGCA CCTACGGGGT TGTGTACAGA GCAAAGGACA AGAAGACAGA TGAAATTGTG 1320

GCTCTAAAGC GACTGAAAAT GGAGAAGGAG AAGGAGGGCT TCCCAATCAC ATCACTGAGG 1380

GAGATCAACA CCATCCTCAA GGCGCAACAC CCCAATATCG TCACTGTCAG GGAGATCGTC 1440

GTGGGCAGCA ACATGGACAA GATCTACATC GTCATGAACT ACGTAGAGCA TGACCTCAAG 1500

AGCCTCATGG AGACCATGAA GCAGCCTTTC CTGCCAGGGG AAGTGAAGAC ACTGATGATC 1560

CAGCTGCTGC GCGGAGTGAA GCACCTCCAC GACAACTGGA TCCTGCACCG AGACCTCAAG 1620

ACGTCCAACC TGCTGTTGAG CCACGCAGGC ATCCTCAAGG TGGGGGACTT CGGGCTGGCA 1680

CGGGAGTATG GGTCCCCTCT GAAGGCCTAC ACCCCAGTGG TCGTGACGCT GTGGTACCGA 1740

GCCCCTGAGC TTTTGCTTGG AGCCAAGGAG TACTCCACAG CCGTGGACAT GTGGTCAGTG 1800

GGCTGCATCT TTGGGGAGCT GCTGACTCAG AAGCCGCTAT TCCCTGGGAA GTCAGAAATC 1860

GATCAGATCA ACAAAGTGTT CAAGGACCTC GGCACCCCCA GTGAGAAAAT CTGGCCTGGC 1920

TACAACGACC TCCCAGCTGT CAAGAAGATG ACCTTCACCG AGTACCCCTA TAACAACCTC 1980

CGCAAGCGCT TCGGGGCTCT GCTCTCAGAC CAGGGCTTTG ACCTCATGAA CAAGTTTCTG 2040

ACATATTTCC CTGGGCGGAG AGTCAACGCA GAAGATGGCC TCAAACATGA GTATTTCCGT 2100

GAGACCCCCC TCCCCATCGA CCCCTCCATG TTCCCCACAT GGCCGGCCAA GAGCGAACAG 2160

CAGAGGGTGA AGCGAGGCAC CAGCCCACGA CCTCCAGAGG GAGGTCTGGG ATACAGCCAG 2220

CTGGGCGACG ATGACCTGAA GGAGACCGGC TTCCACCTCA CCACCACAAA CCAGGGGGCC 2280

TCGGCTGCGG GCCCGGGCTT CAGCCTCAAG TTCTGA 2316

Domain Profile

S: 1     yeklekigeGtygkvykakdketgevvAlKkirlekekegvpitalrEisllkelkhkni  60

         +++l++i+eGtyg+vy+akdk+t+e+vAlK++++ekekeg+pit+lrEi+++ + +h+ni

Q: 414   FQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNI  473

         7899********************************************************

S: 61    vkLlevva.kdkkklyLvfefleqdLkkllkkkkkkklsleevkslllqlleglaylHsn  119

         v++ e+v+ ++ +k+y+v++++e+dLk+l++++k+  + + evk+l++qll+g+++lH+n

Q: 474   VTVREIVVgSNMDKIYIVMNYVEHDLKSLMETMKQ-PFLPGEVKTLMIQLLRGVKHLHDN  532

         *******95666***********************.9999********************

S: 120   kilHRDlKpqNlLiskegklklaDfGlarafssplktytkevvTlwYraPelLlgakeYs  179

         +ilHRDlK++NlL+s+ g+lk++DfGlar+++splk+yt++vvTlwYraPelLlgakeYs

Q: 533   WILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEYS  592

         ************************************************************

S: 180   tavDiWsvgcilaelltrkplfqgkseidqlerifkllgtpsekvwpevsklpeyk.ksf  238

         tavD+Wsvgci+ ellt+kplf+gkseidq++++fk lgtpsek+wp++++lp +k ++f

Q: 593   TAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYNDLPAVKkMTF  652

         ********************************************************99**

S: 239   pkkkkkklkekvkklkek.aldllekllaldpkkRisakealqhkyf  284

         +++++++l++++ +l ++ ++dl++k+l++ p +R++a++ l+h+yf

Q: 653   TEYPYNNLRKRFGALLSDqGFDLMNKFLTYFPGRRVNAEDGLKHEYF  699

         ************8877554***************************9

Domain Sequence
(FASTA)

FQCLNRIEEG TYGVVYRAKD KKTDEIVALK RLKMEKEKEG FPITSLREIN TILKAQHPNI 60

VTVREIVVGS NMDKIYIVMN YVEHDLKSLM ETMKQPFLPG EVKTLMIQLL RGVKHLHDNW 120

ILHRDLKTSN LLLSHAGILK VGDFGLAREY GSPLKAYTPV VVTLWYRAPE LLLGAKEYST 180

AVDMWSVGCI FGELLTQKPL FPGKSEIDQI NKVFKDLGTP SEKIWPGYND LPAVKKMTFT 240

EYPYNNLRKR FGALLSDQGF DLMNKFLTYF PGRRVNAEDG LKHEYF 286

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005634	; C:nucleus
GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0006915	; P:apoptotic process
GO:0001824	; P:blastocyst development
GO:0007088	; P:regulation of mitosis

KEGG

bta:493708

;

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013