EKS-BOT-00209

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-BOT-00209

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDKL	487.5	9.8E-147	4	286	283

Status

Unreviewed

Ensembl Protein

ENSBTAP00000014574

UniProt Accession

E1BM19;

Protein Name

Protein Synonyms/Alias

Gene Name

CDKL3

Gene Synonyms/Alias

CDKL3;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSBTAG00000010979	ENSBTAP00000014574	ENSBTAT00000014574

Organism

Bos taurus

Functional Description

Protein Length

591

Protein Sequence
(FASTA)

MEMYETLGKV GEGSYGTVMK CKHKDTGQIV AIKIFYEKPE KSVNKIAMRE IKFLKQFRHE 60

NLVNLIEVFR QKKKIHLVFE FIDHTVLDEL QHYCHGLESK RLRKYLFQIL RAIEYLHNNN 120

IIHRDIKPEN ILVSQSGITK LCDFGFARTL AAPGDVYTDY VATRWYRAPE LVLKDTSYGK 180

PVDIWALGCM IIEMATGNPY LPSSSDLDLL HKIVLKVGNL TPHLQNIFSK SPIFAGVVLP 240

QVQHPKSARK KYPKLNGLLA DIVHACLQID PAERMSSTDL LHHEYFTRDG FIEKFIPELK 300

AKLLQEAKVN SFIKPKENSK ENDFMKEERK TIYTNTLQST SVWGKELEKE KRPKEIKVRV 360

TKVKGGKGDI LEPKKIVCEG GHCQQVAAEI AHTMSQDTKP VISEPPNPVN PSTNAIGMKD 420

DPCAGGGMVM PPINLTSSNL MASNPNSNLS HSNSRLTERA KKRRTSSQSI GQVISNRHED 480

TGSTQSQMEK CVFNERTSQT DQMANGNKRK LNFPRSDRKE FHFPELPFII QSKEMKGMEV 540

KQIKVLKRES KRTDSSKIPT LLNADQYQEK QEDGDGHCKG KNLKRNRLFF W 591

Nucleotide Sequence
(FASTA)

ATGGAGATGT ATGAAACCCT TGGAAAAGTG GGAGAGGGAA GTTATGGAAC AGTCATGAAG 60

TGTAAACATA AGGATACTGG GCAGATAGTG GCCATTAAGA TATTTTATGA AAAACCAGAA 120

AAGTCTGTCA ACAAAATTGC AATGAGGGAA ATAAAGTTTC TAAAGCAATT TCGTCATGAA 180

AACCTGGTCA ATCTGATTGA AGTTTTTAGA CAGAAAAAGA AAATTCATTT GGTGTTTGAA 240

TTTATTGACC ACACAGTTTT AGATGAGTTA CAACATTATT GTCACGGATT AGAGAGTAAA 300

CGACTTAGAA AATACCTCTT CCAGATTCTT CGAGCAATTG AATATCTTCA CAATAATAAT 360

ATCATTCATC GAGATATAAA ACCTGAGAAT ATTTTAGTAT CCCAATCAGG AATTACTAAA 420

CTCTGTGATT TTGGTTTTGC ACGAACGCTA GCAGCTCCTG GAGATGTTTA TACAGACTAT 480

GTGGCTACAC GCTGGTACAG AGCTCCAGAA TTAGTATTAA AAGATACCTC TTATGGAAAA 540

CCTGTGGATA TCTGGGCTCT GGGCTGTATG ATCATTGAGA TGGCCACTGG AAATCCCTAT 600

CTTCCTAGCA GCTCTGATTT GGATTTACTT CATAAAATTG TTTTAAAAGT AGGCAATTTG 660

ACACCTCACT TGCAGAATAT CTTTTCCAAG AGTCCCATTT TTGCTGGGGT GGTCCTTCCT 720

CAAGTTCAAC ATCCCAAAAG TGCAAGAAAA AAATACCCAA AGCTAAATGG ATTGTTGGCT 780

GACATAGTTC ATGCTTGCTT ACAAATTGAT CCTGCTGAGA GGATGTCATC TACCGATCTT 840

TTGCATCATG AGTATTTTAC TAGAGATGGA TTTATTGAAA AATTCATACC AGAACTGAAA 900

GCTAAATTGC TCCAAGAAGC AAAAGTCAAT TCATTCATAA AACCAAAAGA GAATTCTAAA 960

GAAAATGACT TTATGAAAGA AGAAAGAAAA ACAATTTATA CCAATACACT GCAAAGTACT 1020

TCAGTTTGGG GAAAGGAATT GGAAAAAGAG AAAAGGCCCA AGGAGATCAA AGTCAGAGTT 1080

ACTAAAGTTA AAGGAGGAAA AGGAGATATC TTAGAACCAA AAAAGATAGT GTGTGAAGGT 1140

GGACATTGTC AACAGGTTGC AGCTGAAATT GCTCATACTA TGTCTCAAGA TACAAAACCT 1200

GTAATCAGTG AGCCCCCAAA CCCTGTCAAT CCCAGCACTA ACGCTATAGG CATGAAAGAC 1260

GATCCATGTG CTGGAGGTGG TATGGTAATG CCACCCATCA ATCTAACTAG CAGTAACTTG 1320

ATGGCTTCAA ATCCCAATTC AAACCTCTCC CACTCCAATT CAAGGTTAAC TGAAAGAGCC 1380

AAAAAGAGAC GTACGTCTTC ACAATCTATT GGACAAGTTA TATCTAACAG GCATGAGGAT 1440

ACAGGTTCCA CTCAAAGCCA AATGGAGAAG TGTGTGTTTA ATGAGCGAAC CAGCCAAACT 1500

GACCAAATGG CAAATGGAAA CAAAAGGAAG CTGAATTTTC CCAGATCTGA CAGGAAAGAA 1560

TTCCATTTCC CAGAATTGCC TTTCATAATA CAATCAAAGG AGATGAAAGG AATGGAAGTG 1620

AAACAGATAA AAGTGTTGAA GAGGGAATCA AAGAGAACGG ATTCATCTAA AATACCAACT 1680

TTACTTAATG CAGATCAATA TCAAGAAAAA CAAGAGGATG GAGATGGCCA TTGTAAGGGG 1740

AAGAATTTGA AGAGGAACAG ACTTTTTTTC TGGTAG 1776

Domain Profile

S: 1     yeklgkvGeGsyGvvlkcrnkdtgqivaikkfleseddkevkkialreikllkqlkhenl  60

         ye+lgkvGeGsyG+v+kc++kdtgqivaik f+e+++ k+v+kia+reik+lkq++henl

Q: 4     YETLGKVGEGSYGTVMKCKHKDTGQIVAIKIFYEKPE-KSVNKIAMREIKFLKQFRHENL  62

         9***********************************9.9*********************

S: 61    vnllevfrrkkklylvfeyvdktvldelerypnGveeelvkkilyqilkaiefchknnii  120

         vnl+evfr+kkk++lvfe++d+tvldel++y++G+e+++++k+l+qil+aie++h+nnii

Q: 63    VNLIEVFRQKKKIHLVFEFIDHTVLDELQHYCHGLESKRLRKYLFQILRAIEYLHNNNII  122

         ************************************************************

S: 121   hrdikpenilisksgvvklcdfGfarllaapgdvytdyvatrwyrapellvgdtkyGksv  180

         hrdikpenil+s+sg++klcdfGfar+laapgdvytdyvatrwyrapel+++dt+yGk+v

Q: 123   HRDIKPENILVSQSGITKLCDFGFARTLAAPGDVYTDYVATRWYRAPELVLKDTSYGKPV  182

         ************************************************************

S: 181   dvwaiGcllaelltGeplfpgksdvdqlykirktlGeliprhqkifsknevfaGvklpev  240

         d+wa+Gc+++e++tG+p++p++sd+d l+ki+ ++G+l+p+ q+ifsk+++faGv+lp+v

Q: 183   DIWALGCMIIEMATGNPYLPSSSDLDLLHKIVLKVGNLTPHLQNIFSKSPIFAGVVLPQV  242

         ************************************************************

S: 241   edleslekkypklnevlldllkkclkldpaerlsceellkheyf  284

         ++++s++kkypkln +l+d++++cl++dpaer+s+++ll+heyf

Q: 243   QHPKSARKKYPKLNGLLADIVHACLQIDPAERMSSTDLLHHEYF  286

         *******************************************9

Domain Sequence
(FASTA)

YETLGKVGEG SYGTVMKCKH KDTGQIVAIK IFYEKPEKSV NKIAMREIKF LKQFRHENLV 60

NLIEVFRQKK KIHLVFEFID HTVLDELQHY CHGLESKRLR KYLFQILRAI EYLHNNNIIH 120

RDIKPENILV SQSGITKLCD FGFARTLAAP GDVYTDYVAT RWYRAPELVL KDTSYGKPVD 180

IWALGCMIIE MATGNPYLPS SSDLDLLHKI VLKVGNLTPH LQNIFSKSPI FAGVVLPQVQ 240

HPKSARKKYP KLNGLLADIV HACLQIDPAE RMSSTDLLHH EYF 283

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Equus caballus"; ?>Felis catus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Vicugna pacos"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

bta:541279

;

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013