EKS-BOT-00150

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-BOT-00150

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/NDR	521.9	4.6E-157	90	383	294

Status

Unreviewed

Ensembl Protein

ENSBTAP00000040838

UniProt Accession

A7MB32;

Protein Name

Protein Synonyms/Alias

STK38L protein;

Gene Name

STK38L

Gene Synonyms/Alias

STK38L;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSBTAG00000011798	ENSBTAP00000040838	ENSBTAT00000043251

Organism

Bos taurus

Functional Description

Protein Length

464

Protein Sequence
(FASTA)

MAMTAGSTTT FPMSNHTRER VTVAKLTLEN FYSNLILQHE ERETRQKKLE VAMEEEGLAD 60

EEKKLRRSQH ARKETEFLRL KRTRLGLDDF ESLKVIGRGA FGEVRLVQKK DTGHIYAMKI 120

LRKADMLEKE QVAHIRAERD ILVEADGAWV VKMFYSFQDK RNLYLIMEFL PGGDMMTLLM 180

KKDTLTEEET QFYISETVLA IDAIHQLGFI HRDIKPDNLL LDAKGHVKLS DFGLCTGLKK 240

AHRTEFYRNL THNPPSDFSF QNMNSKRKAE TWKKNRRQLA YSTVGTPDYI APEVFMQTGY 300

NKLCDWWSLG VIMYEMLIGY PPFCSETPQE TYRKVMNWKE TLVFPPEVPI SEKAKDLILR 360

FCIDSENRIG NSGVEEIKSH PFFEGVDWGH IRERPAAIPI EIKSIDDTSN FDDFPESDIL 420

QPVPNTTEPD YKSKDWVFLN YTYKRFEGLT QRGSIPTYMK AGKL 464

Nucleotide Sequence
(FASTA)

ATGGCAATGA CGGCAGGGTC TACAACCACC TTTCCTATGA GCAACCATAC CCGTGAAAGA 60

GTGACCGTCG CCAAGCTCAC ATTGGAGAAT TTTTACAGCA ACCTAATTTT ACAGCATGAA 120

GAGAGAGAAA CCAGGCAGAA GAAATTAGAA GTGGCTATGG AAGAAGAAGG ATTAGCAGAT 180

GAAGAGAAAA AGTTACGCCG ATCACAGCAT GCTCGCAAGG AGACAGAGTT CTTACGGCTC 240

AAGCGGACCA GACTTGGCCT GGATGACTTT GAGTCTCTGA AAGTTATAGG AAGAGGAGCG 300

TTCGGAGAGG TGCGGCTGGT CCAGAAGAAA GATACAGGCC ATATCTATGC AATGAAGATA 360

TTGAGAAAAG CTGATATGCT TGAAAAAGAG CAGGTGGCCC ATATCCGAGC AGAAAGAGAT 420

ATTTTGGTAG AAGCAGATGG TGCCTGGGTG GTGAAGATGT TTTACAGTTT TCAAGACAAG 480

AGGAACCTTT ATCTAATCAT GGAATTTCTC CCTGGAGGTG ACATGATGAC ATTGCTAATG 540

AAGAAGGATA CTTTGACAGA AGAGGAAACA CAGTTCTACA TTTCAGAGAC TGTTCTGGCA 600

ATAGATGCAA TCCACCAGTT GGGTTTCATC CATCGGGATA TTAAACCAGA CAACCTTTTG 660

TTAGATGCCA AGGGTCATGT AAAATTATCT GATTTTGGTT TGTGCACGGG ATTAAAGAAG 720

GCTCATAGGA CTGAATTCTA TAGAAATCTT ACCCACAACC CACCAAGTGA CTTCTCATTC 780

CAGAACATGA ACTCAAAGAG GAAAGCAGAA ACATGGAAGA AGAATAGGAG ACAACTGGCA 840

TATTCAACAG TTGGGACACC AGATTACATT GCTCCAGAAG TATTCATGCA GACTGGCTAC 900

AACAAATTGT GTGACTGGTG GTCTTTGGGA GTAATTATGT ATGAAATGCT AATAGGATAT 960

CCACCTTTCT GCTCTGAAAC ACCTCAAGAA ACATACAGGA AAGTGATGAA CTGGAAAGAA 1020

ACTCTGGTAT TTCCTCCAGA GGTGCCTATA TCTGAGAAAG CCAAGGACTT AATTCTTAGG 1080

TTTTGTATTG ATTCTGAAAA TAGAATTGGG AATAGTGGAG TAGAAGAAAT AAAAAGTCAT 1140

CCTTTTTTTG AAGGCGTCGA CTGGGGGCAC ATCAGGGAAA GGCCAGCAGC AATCCCTATA 1200

GAAATCAAAA GCATTGATGA TACGTCAAAT TTCGATGACT TTCCTGAATC TGATATTTTA 1260

CAACCAGTGC CAAACACCAC GGAACCGGAC TACAAATCCA AAGACTGGGT TTTCCTCAAT 1320

TATACCTATA AGAGGTTCGA AGGGTTGACT CAGCGTGGCT CTATCCCCAC CTACATGAAG 1380

GCTGGGAAAT TATGA 1395

Domain Profile

S: 1     feklkvigkGafGevrlvrkkdtkevyalkilrkkdllkknqvahvkaerdilaeadsew  60

         fe+lkvig+GafGevrlv+kkdt+++ya+kilrk+d+l+k+qvah++aerdil+ead +w

Q: 90    FESLKVIGRGAFGEVRLVQKKDTGHIYAMKILRKADMLEKEQVAHIRAERDILVEADGAW  149

         899*********************************************************

S: 61    vvklyysfqdkenlylvmeylPGGdlmtllikkeilkeelarfyiaelvlavesvhklGf  120

         vvk++ysfqdk+nlyl+me+lPGGd+mtll+kk++l+ee+++fyi+e+vla++++h+lGf

Q: 150   VVKMFYSFQDKRNLYLIMEFLPGGDMMTLLMKKDTLTEEETQFYISETVLAIDAIHQLGF  209

         ************************************************************

S: 121   ihrdlkPdnllidakGhikltdfGlctGlkkthrseyykelekakeddleaseelkvler  180

         ihrd+kPdnll+dakGh+kl+dfGlctGlkk+hr+e+y++l+++ ++d+++++  ++ +

Q: 210   IHRDIKPDNLLLDAKGHVKLSDFGLCTGLKKAHRTEFYRNLTHNPPSDFSFQNMNSKRKA  269

         *************************************************65555555555

S: 181   rkkkknrrllayslvGtpdyiapevlekkgynklcdwWslGvilyemlvGypPflaetpq  240

            kknrr+lays+vGtpdyiapev++++gynklcdwWslGvi+yeml+GypPf++etpq

Q: 270   ETWKKNRRQLAYSTVGTPDYIAPEVFMQTGYNKLCDWWSLGVIMYEMLIGYPPFCSETPQ  329

         555*********************************************************

S: 241   etykkvinwketlkfpeevelseeakdlierliadaekrlgkkGvdeikkhpff  294

         ety+kv+nwketl fp+ev++se+akdli r+++d+e+r+g++Gv+eik+hpff

Q: 330   ETYRKVMNWKETLVFPPEVPISEKAKDLILRFCIDSENRIGNSGVEEIKSHPFF  383

         *****************************************************9

Domain Sequence
(FASTA)

FESLKVIGRG AFGEVRLVQK KDTGHIYAMK ILRKADMLEK EQVAHIRAER DILVEADGAW 60

VVKMFYSFQD KRNLYLIMEF LPGGDMMTLL MKKDTLTEEE TQFYISETVL AIDAIHQLGF 120

IHRDIKPDNL LLDAKGHVKL SDFGLCTGLK KAHRTEFYRN LTHNPPSDFS FQNMNSKRKA 180

ETWKKNRRQL AYSTVGTPDY IAPEVFMQTG YNKLCDWWSL GVIMYEMLIG YPPFCSETPQ 240

ETYRKVMNWK ETLVFPPEVP ISEKAKDLIL RFCIDSENRI GNSGVEEIKS HPFF 294

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Caenorhabditis elegans"; ?>Canis familiaris"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>

Gene Ontology

GO:0015629	; C:actin cytoskeleton
GO:0005737	; C:cytoplasm
GO:0005634	; C:nucleus
GO:0005886	; C:plasma membrane
GO:0005524	; F:ATP binding
GO:0000287	; F:magnesium ion binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0007243	; P:intracellular protein kinase cascade
GO:0051128	; P:regulation of cellular component organization

KEGG

bta:514787

;

InterPros

IPR000961	; AGC-kinase_C.
IPR011009	; Kinase-like_dom.
IPR017892	; Pkinase_C.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069	; Pkinase; 1.
PF00433	; Pkinase_C; 1.

SMARTs

SM00133	; S_TK_X; 1.
SM00220	; S_TKc; 1.

Prosites

PS51285	; AGC_KINASE_CTER; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013