EKS-BOT-00415

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-BOT-00415

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/DAPK	438.7	6.9E-132	35	293	259

Status

Unreviewed

Ensembl Protein

ENSBTAP00000017564

UniProt Accession

F1MSI1;

Protein Name

Protein Synonyms/Alias

Gene Name

STK17B

Gene Synonyms/Alias

STK17B;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSBTAG00000013196	ENSBTAP00000017564	ENSBTAT00000017564

Organism

Bos taurus

Functional Description

Protein Length

372

Protein Sequence
(FASTA)

MLRRRFDCRS ISGMLTTTPQ TPIKVENFNN FYTLTSKELG RGKFAVVRQC ISKSTGQEYA 60

AKFLKKRRRG QDCRAEILHE IAVLELTKSC PHVINLHEVY ENTSEIILIL EYAAGGEIFN 120

LCLPELAEMV SENDIIRLIK QILEGVHYLH QNNIVHLDLK PQNILLSSIY PLGDIKIVDF 180

GMSRKIGNAC ELREIMGTPE YLAPEILNYD PITTATDMWN VGVIAYMLLT HTSPFVGEDN 240

QETYLNISQV NVDYSEETFS SVSQLATDFI QRLLVKNPEK RPTAEICLSH SWLQQWDFGN 300

LFHPEETSSF SQSQDHPVRS SEDRTHRPSC NGTCSDREDK ENIPEDSSTV SKRFRFDDSL 360

PSPHELVSDL LC 372

Nucleotide Sequence
(FASTA)

ATGTTGAGGA GAAGATTTGA TTGCCGAAGT ATTTCAGGCA TGCTAACTAC CACTCCTCAA 60

ACTCCAATTA AAGTGGAAAA CTTTAATAAT TTTTATACAC TTACATCTAA AGAACTGGGA 120

AGAGGAAAAT TTGCTGTGGT TAGACAATGT ATATCAAAAT CTACTGGACA AGAATATGCT 180

GCAAAGTTTC TAAAAAAGAG AAGAAGAGGA CAGGACTGTC GAGCAGAGAT TCTACATGAA 240

ATTGCAGTAC TTGAATTGAC AAAATCTTGT CCCCACGTGA TTAATCTTCA TGAAGTCTAT 300

GAAAATACAA GTGAAATCAT TTTGATATTG GAATATGCTG CAGGTGGAGA AATTTTTAAT 360

TTGTGTTTAC CTGAGTTGGC TGAAATGGTT TCTGAAAATG ACATTATCAG ACTCATTAAA 420

CAAATACTTG AAGGAGTTCA TTACCTACAT CAGAATAACA TTGTACACCT TGATTTAAAG 480

CCCCAGAATA TATTATTGAG CAGCATATAT CCTCTTGGGG ACATAAAAAT TGTAGATTTT 540

GGAATGTCTC GAAAAATAGG AAATGCATGT GAACTTCGGG AAATCATGGG AACACCAGAA 600

TACTTGGCTC CAGAAATCCT GAACTACGAT CCCATTACCA CAGCAACAGA TATGTGGAAT 660

GTTGGTGTAA TAGCATATAT GTTATTAACT CACACATCCC CATTTGTGGG AGAAGATAAT 720

CAGGAAACAT ACCTCAATAT TTCTCAAGTT AATGTAGATT ATTCGGAAGA AACTTTTTCA 780

TCAGTTTCAC AGCTGGCCAC AGACTTCATC CAGAGGCTTT TAGTAAAAAA TCCAGAGAAA 840

AGACCTACAG CCGAAATCTG CCTTTCTCAT TCTTGGCTAC AGCAGTGGGA CTTTGGAAAC 900

TTGTTTCACC CTGAAGAAAC CTCCAGTTTC TCTCAAAGTC AGGATCATCC AGTAAGGTCC 960

TCTGAGGACA GGACTCACAG GCCCTCTTGT AATGGCACCT GCAGTGACCG GGAAGACAAA 1020

GAGAACATCC CAGAGGACAG CAGCACGGTG TCCAAGAGAT TCCGCTTTGA CGACTCGCTG 1080

CCCAGCCCCC ACGAGCTTGT GTCCGATTTG CTCTGTTAG 1119

Domain Profile

S: 3     tgkelgsGkfavvrkcrekstGkeyaakflkkrrlkssrrgvsreeierevavlkeirse  62

         t+kelg+Gkfavvr+c++kstG+eyaakflkkrr    r++++r+ei +e+avl++ +s+

Q: 35    TSKELGRGKFAVVRQCISKSTGQEYAAKFLKKRR----RGQDCRAEILHEIAVLELTKSC  90

         789*******************************....**********************

S: 63    pnvinlhevyenksdvililelvaGGelfd..llaekeslseeeatellkqilegvkylh  120

         p+vinlhevyen+s++ilile++aGGe+f+  l + +e++se+++++l+kqilegv+ylh

Q: 91    PHVINLHEVYENTSEIILILEYAAGGEIFNlcLPELAEMVSENDIIRLIKQILEGVHYLH  150

         ******************************877899************************

S: 121   skkivhldlkPenillldkkvpkgdiklidfGlsrkieegaelkeilGtPefvaPeivny  180

         +++ivhldlkP+nill++ + p gdik++dfG+srki +++el+ei+GtPe++aPei+ny

Q: 151   QNNIVHLDLKPQNILLSSIY-PLGDIKIVDFGMSRKIGNACELREIMGTPEYLAPEILNY  209

         ********************.***************************************

S: 181   eplsletdmwsiGvityillsgasPflGdtkqetllnisavnldfseelfssvselakdf  240

         +p++++tdmw++Gvi+y+ll+++sPf+G+++qet+lnis+vn+d+see+fssvs+la+df

Q: 210   DPITTATDMWNVGVIAYMLLTHTSPFVGEDNQETYLNISQVNVDYSEETFSSVSQLATDF  269

         ************************************************************

S: 241   irrllvkdpekrltieeclehswl  264

         i+rllvk+pekr t+e cl+hswl

Q: 270   IQRLLVKNPEKRPTAEICLSHSWL  293

         ***********************7

Domain Sequence
(FASTA)

TSKELGRGKF AVVRQCISKS TGQEYAAKFL KKRRRGQDCR AEILHEIAVL ELTKSCPHVI 60

NLHEVYENTS EIILILEYAA GGEIFNLCLP ELAEMVSEND IIRLIKQILE GVHYLHQNNI 120

VHLDLKPQNI LLSSIYPLGD IKIVDFGMSR KIGNACELRE IMGTPEYLAP EILNYDPITT 180

ATDMWNVGVI AYMLLTHTSP FVGEDNQETY LNISQVNVDY SEETFSSVSQ LATDFIQRLL 240

VKNPEKRPTA EICLSHSWL 259

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005634	; C:nucleus
GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0006917	; P:induction of apoptosis

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013