EKS-BOT-00204

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-BOT-00204

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/RCK	513.8	1.3E-154	4	284	281

Status

Unreviewed

Ensembl Protein

ENSBTAP00000018676

UniProt Accession

E1BDG4;

Protein Name

Protein Synonyms/Alias

Gene Name

MAK

Gene Synonyms/Alias

MAK;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSBTAG00000014053	ENSBTAP00000034540	ENSBTAT00000034653
ENSBTAG00000014053	ENSBTAP00000018676	ENSBTAT00000018676

Organism

Bos taurus

Functional Description

Protein Length

382

Protein Sequence
(FASTA)

MNRYTTMRQL GDGTYGSVLM GKSNESGELV AIKRMKRKFY SWDECMNLRE VKSLKKLNHA 60

NVIKLKEVIR ENDHLYFIFE YMKENLYQLM KDRNKLFPES VIRNIMYQIL QGLAFIHKHG 120

FFHRDMKPEN LLCMGPELVK IADFGLAREL RSQPPYTDYV STRWYRAPEV LLRSSAYSSP 180

IDVWAVGSIM AELYTLRPLF PGTSEVDEIF KICQVLGTPK KSDWPEGYQL ASSMNFRFPQ 240

CVPINLKTLI PNASNEAIQL MTEMLNWDPK KRPTASQALK HPYFQVGQVL GPSSHHLESK 300

QPLNKLVQPL EPKPSAADPE PQPLPDINDQ AAGPPQLKNS HQPLRSIQPP QNVGVQPAPK 360

QHSQQKRPPT LFPSIVKSMP TT 382

Nucleotide Sequence
(FASTA)

ATGAACCGGT ACACGACCAT GAGACAGCTG GGGGACGGCA CGTACGGGAG CGTGCTCATG 60

GGCAAGAGCA ACGAGTCCGG GGAGCTGGTG GCCATCAAAA GAATGAAGAG AAAGTTCTAT 120

TCTTGGGATG AATGTATGAA CTTGAGAGAA GTTAAGTCTC TGAAGAAACT TAATCATGCC 180

AATGTGATCA AACTGAAAGA AGTTATCAGA GAAAATGACC ATCTTTATTT TATATTTGAA 240

TATATGAAAG AAAACCTCTA TCAATTAATG AAAGACAGAA ACAAGTTGTT CCCTGAGTCT 300

GTCATCAGAA ATATTATGTA TCAGATATTG CAGGGGCTGG CATTTATCCA TAAACATGGT 360

TTTTTCCATA GGGACATGAA ACCGGAAAAC TTGCTTTGTA TGGGCCCAGA ACTTGTGAAA 420

ATTGCTGACT TTGGACTTGC GAGAGAACTA AGGTCACAGC CCCCGTATAC GGACTATGTA 480

TCCACCAGAT GGTATCGCGC TCCTGAGGTT TTATTAAGAT CTTCAGCTTA CAGCTCTCCC 540

ATCGACGTGT GGGCTGTCGG CAGTATAATG GCTGAACTGT ATACATTAAG ACCACTTTTC 600

CCAGGGACAA GTGAGGTCGA TGAAATCTTT AAGATTTGCC AGGTTTTAGG GACTCCTAAA 660

AAAAGTGACT GGCCAGAAGG GTACCAGCTT GCATCCTCTA TGAATTTCCG CTTTCCCCAG 720

TGTGTTCCTA TAAACCTAAA AACTCTTATT CCCAATGCCA GTAACGAAGC CATTCAGCTT 780

ATGACTGAAA TGTTGAACTG GGACCCAAAG AAACGACCAA CAGCAAGCCA GGCCTTGAAA 840

CACCCATATT TTCAAGTTGG TCAAGTATTA GGCCCTTCCT CACATCATTT GGAATCGAAA 900

CAGCCTTTAA ATAAGCTTGT GCAACCACTC GAACCAAAGC CATCTGCAGC AGATCCAGAA 960

CCTCAGCCTC TGCCGGACAT AAACGACCAG GCTGCCGGAC CGCCCCAGCT GAAGAACAGC 1020

CACCAGCCAC TGCGGTCTAT CCAGCCGCCG CAGAACGTGG GTGTCCAGCC AGCACCCAAA 1080

CAGCACAGTC AGCAGAAAAG GCCGCCAACC CTCTTTCCAA GTATCGTCAA AAGCATGCCC 1140

ACCACATAA 1149

Domain Profile

S: 1     yklikklGdGtfgevllakslktgelvaikkmkrkfesleevtnlrevkslkklnahdni  60

         y+++++lGdGt+g+vl++ks+++gelvaik+mkrkf+s++e++nlrevkslkkln h+n+

Q: 4     YTTMRQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSLKKLN-HANV  62

         99*****************************************************.****

S: 61    iklkeviidrendslylvlelmeenlyqlikdrrkllsesklksilyqilkglafihkhg  120

         iklkevi  rend+ly+++e+m+enlyql+kdr+kl++es++++i+yqil+glafihkhg

Q: 63    IKLKEVI--RENDHLYFIFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKHG  120

         *******..***************************************************

S: 121   ffhrdlkPenilikgselvkladfGlarevrsknPytdyvstrwyraPevllrsgvyssp  180

         ffhrd+kPen+l++g+elvk+adfGlare+rs++PytdyvstrwyraPevllrs+ yssp

Q: 121   FFHRDMKPENLLCMGPELVKIADFGLARELRSQPPYTDYVSTRWYRAPEVLLRSSAYSSP  180

         ************************************************************

S: 181   ldlwavGcvlaevavlrplfPGaseidqifkilevlGtPkkkewdeayklasalnlkfpq  240

         +d+wavG+++ae+++lrplfPG+se+d+ifki++vlGtPkk++w+e+y+las++n++fpq

Q: 181   IDVWAVGSIMAELYTLRPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQLASSMNFRFPQ  240

         ************************************************************

S: 241   vegsslktlvsnaskealellkdllaydPderataqqalkypyf  284

         +++++lktl++nas+ea++l++++l++dP++r+ta+qalk+pyf

Q: 241   CVPINLKTLIPNASNEAIQLMTEMLNWDPKKRPTASQALKHPYF  284

         *******************************************9

Domain Sequence
(FASTA)

YTTMRQLGDG TYGSVLMGKS NESGELVAIK RMKRKFYSWD ECMNLREVKS LKKLNHANVI 60

KLKEVIREND HLYFIFEYMK ENLYQLMKDR NKLFPESVIR NIMYQILQGL AFIHKHGFFH 120

RDMKPENLLC MGPELVKIAD FGLARELRSQ PPYTDYVSTR WYRAPEVLLR SSAYSSPIDV 180

WAVGSIMAEL YTLRPLFPGT SEVDEIFKIC QVLGTPKKSD WPEGYQLASS MNFRFPQCVP 240

INLKTLIPNA SNEAIQLMTE MLNWDPKKRP TASQALKHPY F 281

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Tursiops truncatus"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005813	; C:centrosome
GO:0030496	; C:midbody
GO:0072686	; C:mitotic spindle
GO:0005634	; C:nucleus
GO:0001917	; C:photoreceptor inner segment
GO:0001750	; C:photoreceptor outer segment
GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0003713	; F:transcription coactivator activity
GO:0045494	; P:photoreceptor cell maintenance
GO:0046777	; P:protein autophosphorylation

KEGG

bta:536048

;

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013