EPS-BOT-00026

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-BOT-00026

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	204.2	3.2E-60	59	315	257

Status

Unreviewed

Ensembl Protein

ENSBTAP00000056415

UniProt Accession

G3N3B3;

Protein Name

Protein Synonyms/Alias

Gene Name

PPM1N

Gene Synonyms/Alias

PPM1N;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSBTAG00000014187	ENSBTAP00000056415	ENSBTAT00000063255
ENSBTAG00000014187	ENSBTAP00000018867	ENSBTAT00000018867

Organism

Bos taurus

Functional Description

Protein Length

422

Protein Sequence
(FASTA)

MAALARLLER LLWPARKEEE AEEEEEGCRS PNRPQSLLDA PRCAQRPHGG AAAAWGLRFG 60

ASAVQGWRAH MEDAHCACLA LPGLPPGWAF FAVLDGHGGA RAALFGARHL KGQVLEALGP 120

EPSEPQGVCE ALRRAFLSAD ARLRALWPRG EPGGSTAVAL LVSPRFLYLA HCGDSRAVLS 180

RAGAVAFSTE DHRPLRPRER ERIHDAGGTI SRRRLEGSLA VSRALGDFAY KEAPGRPPEQ 240

QLVSAEPEVT ALARQAEDEF MLLASDGVWD AMSGSALVGL VASRLCLGLA PELLCAQLLD 300

TCLCKGSLDN MTCLLVCFPG APRPCEEAIR KEVLLDAALG RRVAELCASA SEPPSLNTVF 360

RTLASEDILD LPPGGGLYCK ATVIAEAYSQ FCQASRQRCV KGQKGAEEPT GALSVSALHL 420

EA 422

Nucleotide Sequence
(FASTA)

ATGGCGGCCC TTGCCCGCCT GCTGGAACGT CTCCTTTGGC CAGCCCGCAA GGAAGAGGAG 60

GCGGAGGAAG AAGAGGAGGG ATGCAGGTCT CCCAACCGGC CTCAGTCCCT CCTAGACGCG 120

CCGCGTTGCG CCCAGCGGCC GCACGGGGGT GCGGCGGCGG CGTGGGGTCT GCGCTTCGGG 180

GCTAGCGCAG TGCAGGGCTG GCGCGCACAC ATGGAGGATG CTCATTGCGC TTGCCTTGCG 240

CTACCTGGGC TGCCCCCGGG CTGGGCTTTC TTCGCAGTCC TCGACGGCCA CGGCGGGGCA 300

AGAGCCGCCC TCTTCGGCGC GCGCCACCTG AAGGGCCAAG TACTTGAGGC TCTAGGCCCG 360

GAGCCCAGCG AGCCCCAGGG AGTGTGCGAA GCACTGCGCC GCGCCTTTCT GAGCGCAGAC 420

GCGCGCCTGC GTGCTCTCTG GCCCCGCGGC GAGCCTGGGG GCTCCACCGC TGTGGCGTTA 480

CTGGTTTCCC CGCGCTTTCT GTACCTGGCG CACTGCGGTG ACTCTCGCGC GGTGCTAAGT 540

CGCGCCGGCG CCGTGGCCTT CAGCACCGAG GACCATCGGC CCCTCCGTCC CCGAGAACGT 600

GAACGCATCC ATGACGCGGG TGGCACCATC AGCCGTCGGC GCCTCGAGGG CTCTTTGGCA 660

GTGTCCAGAG CCCTGGGAGA CTTTGCCTAC AAAGAGGCTC CAGGAAGGCC CCCAGAACAG 720

CAACTCGTTT CCGCGGAGCC TGAGGTGACC GCCCTGGCAC GCCAAGCGGA GGACGAGTTC 780

ATGCTCTTGG CTTCTGATGG CGTGTGGGAC GCGATGTCCG GGTCTGCCCT AGTGGGACTG 840

GTGGCATCGC GCCTCTGTTT GGGCTTGGCC CCGGAGCTTC TCTGCGCGCA GCTGTTGGAC 900

ACGTGTCTTT GCAAGGGCAG CCTGGACAAC ATGACCTGCC TCCTGGTCTG CTTTCCGGGG 960

GCTCCCAGAC CTTGTGAGGA GGCCATCAGG AAGGAGGTAC TGCTCGATGC AGCCCTGGGA 1020

CGCAGAGTTG CAGAGCTGTG TGCTTCTGCC TCAGAGCCCC CCAGCTTGAA CACAGTTTTC 1080

AGGACTCTGG CCTCTGAGGA CATCCTGGAT TTACCTCCTG GGGGAGGACT CTACTGCAAG 1140

GCCACAGTCA TCGCTGAAGC TTATTCTCAG TTCTGCCAGG CCTCAAGACA GCGCTGCGTG 1200

AAGGGGCAGA AAGGGGCTGA GGAACCCACT GGCGCCCTTT CAGTCTCTGC CTTGCACTTG 1260

GAGGCTTAA 1269

Domain Profile

S: 3     vgvvsvngrrnemedavtsspnflkspekkdrlaffgvyDGhggsevakfcseklheila  62

         +g ++v+g+r +meda+ +    l+ p+    +aff+v DGhgg ++a f + +l+  +

Q: 59    FGASAVQGWRAHMEDAHCAC---LALPGLPPGWAFFAVLDGHGGARAALFGARHLKGQVL  115

         7899*************764...444444445****************************

S: 63    eelesseseerkvkkalakaFlstdeelkvleeksldidksGstavvalikdsklyvanv  122

         e l  + se + v++al++aFls d +l    +   + ++ Gstav  l+++  ly a++

Q: 116   EALGPEPSEPQGVCEALRRAFLSADARL---RALWPRGEPGGSTAVALLVSPRFLYLAHC  172

         ****999*********************...555556999********************

S: 123   GdSravLcrngkavelssdHkpsredEleRieeaggsvilkdgaRvlGvLavsRalGdly  182

         GdSravL+r g +   ++dH+p r++E+eRi +agg++ ++   R+ G+LavsRalGd+

Q: 173   GDSRAVLSRAGAVAFSTEDHRPLRPRERERIHDAGGTISRR---RLEGSLAVSRALGDFA  229

         ************9**************************99...****************

S: 183   lk.........pyvtpePevtshrltsedefliLasDGlwdvvsneeavslvrdvlekke  233

         +k         ++v++ePevt   ++ edef+ LasDG+wd +s  ++v lv ++l  +

Q: 230   YKeapgrppeqQLVSAEPEVTALARQAEDEFMLLASDGVWDAMSGSALVGLVASRLCLGL  289

         ********************************************************99**

S: 234   aeqeaakkLvklalargskdnvsaiv  259

         a++  + +L++++l +gs dn++ ++

Q: 290   APELLCAQLLDTCLCKGSLDNMTCLL  315

         **********************8776

Domain Sequence
(FASTA)

FGASAVQGWR AHMEDAHCAC LALPGLPPGW AFFAVLDGHG GARAALFGAR HLKGQVLEAL 60

GPEPSEPQGV CEALRRAFLS ADARLRALWP RGEPGGSTAV ALLVSPRFLY LAHCGDSRAV 120

LSRAGAVAFS TEDHRPLRPR ERERIHDAGG TISRRRLEGS LAVSRALGDF AYKEAPGRPP 180

EQQLVSAEPE VTALARQAED EFMLLASDGV WDAMSGSALV GLVASRLCLG LAPELLCAQL 240

LDTCLCKGSL DNMTCLL 257

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Felis catus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Macaca mulatta"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Nomascus leucogenys"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sorex araneus"; ?>

Gene Ontology

GO:0000287	; F:magnesium ion binding
GO:0030145	; F:manganese ion binding
GO:0004721	; F:phosphoprotein phosphatase activity
GO:0008152	; P:metabolic process

KEGG

InterPros

IPR001932	; PP2C-like.
IPR012911	; PP2C_C.
IPR015655	; Protein_Pase_2C.

Pfam

PF00481	; PP2C; 1.
PF07830	; PP2C_C; 1.

SMARTs

SM00331	; PP2C_SIG; 1.
SM00332	; PP2Cc; 1.

Prosites

Prints

Created Date

20-Feb-2013