EKS-BOT-00323

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-BOT-00323

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
STE/STE20	329.1	2.2E-98	17	291	275

Status

Unreviewed

Ensembl Protein

ENSBTAP00000019872

UniProt Accession

F1MYV9;

Protein Name

Protein Synonyms/Alias

Gene Name

OXSR1

Gene Synonyms/Alias

OXSR1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSBTAG00000014927	ENSBTAP00000019872	ENSBTAT00000019872

Organism

Bos taurus

Functional Description

Protein Length

527

Protein Sequence
(FASTA)

MTEDSSALPW SINRDDYELQ EVIGSGATAV VQAAYCAPKK EKVAIKRINL EKCQTSMDEL 60

LKEIQAMSQC HHPNIVSYYT SFVVKDELWL VMKLLSGGSV LDIIKHIVAK GEHKNGVLDE 120

ATIATILKEV LEGLEYLHKN GQIHRDVKAG NILLGEDGSV QIADFGVSAF LATGGDITRN 180

KVRKTFVGTP CWMAPEVMEQ VRGYDFKADI WSFGITAIEL ATGAAPYHKY PPMKVLMLTL 240

QNDPPSLETG VQDKEMLKKY GKSFRKMISL CLQKDPEKRP TAAELLRHKF FQKAKNKEFL 300

QEKILQRAPT ISERAKKVRR VPGSSGRLHK TEDGGWEWSD DEFDEESEEG KAAISQLRSP 360

RVKESLTNSE LFSTTDPVGT LLQVPEQISA HLPQPAGPTP AQPTQVSLPP TAEPAIAAQA 420

LSSGAGSQET KIPISLVLRL RNSKKELNDI RFEFTPGRDT AEGVSQELIS AGLVDGRDLV 480

IVAANLQKIV EEPQSNRSVT FKLASGVEGS DIPDDGKLIG FAQLSIS 527

Nucleotide Sequence
(FASTA)

ATGACCGAGG ACTCCAGTGC CCTGCCCTGG TCCATCAACA GGGACGATTA CGAGCTGCAG 60

GAGGTGATAG GGAGTGGAGC AACGGCTGTG GTCCAAGCAG CGTATTGTGC CCCTAAAAAG 120

GAGAAAGTGG CAATCAAACG GATAAACCTT GAGAAATGTC AGACTAGCAT GGATGAACTC 180

CTGAAAGAAA TCCAAGCCAT GAGTCAGTGC CATCACCCTA ATATTGTGTC TTACTACACA 240

TCTTTTGTGG TAAAAGATGA GCTGTGGCTC GTCATGAAGC TGTTAAGTGG AGGTTCTGTT 300

CTAGATATTA TTAAGCACAT TGTGGCAAAG GGGGAACATA AAAATGGGGT CCTGGATGAA 360

GCTACCATCG CTACAATACT CAAAGAAGTG CTGGAGGGTT TGGAATACCT GCATAAAAAT 420

GGACAAATTC ACAGAGATGT GAAAGCTGGC AATATTCTTC TTGGAGAAGA TGGCTCGGTA 480

CAGATTGCAG ACTTTGGAGT TAGTGCTTTT TTAGCAACTG GTGGTGACAT TACTCGGAAT 540

AAAGTGAGAA AAACCTTTGT TGGAACACCT TGCTGGATGG CGCCTGAAGT TATGGAACAG 600

GTTCGTGGTT ATGATTTTAA AGCTGACATC TGGAGTTTTG GGATCACAGC CATTGAACTG 660

GCCACGGGGG CAGCTCCTTA CCATAAGTAC CCACCGATGA AGGTTTTAAT GCTGACACTG 720

CAGAATGATC CTCCTTCTTT GGAAACTGGT GTTCAAGATA AAGAAATGCT GAAAAAATAT 780

GGAAAATCAT TTAGAAAAAT GATTTCATTG TGCCTTCAAA AAGATCCAGA AAAAAGACCA 840

ACAGCAGCAG AACTGCTAAG GCACAAGTTT TTCCAAAAAG CCAAGAATAA AGAATTTCTT 900

CAAGAAAAAA TATTGCAGAG AGCACCAACC ATTTCTGAAA GAGCTAAAAA GGTTCGGAGA 960

GTACCAGGCT CTAGTGGCCG TCTTCACAAG ACAGAAGATG GTGGCTGGGA GTGGAGTGAT 1020

GATGAATTTG ATGAAGAAAG TGAGGAAGGA AAAGCAGCAA TTTCACAACT CAGGTCTCCC 1080

AGAGTGAAAG AATCATTAAC AAATTCTGAG CTATTTTCCA CAACTGATCC TGTGGGTACT 1140

TTACTCCAAG TTCCAGAACA GATTTCTGCT CATCTACCTC AGCCAGCAGG GCCGACGCCT 1200

GCACAACCCA CTCAAGTCTC CCTGCCACCC ACTGCAGAGC CAGCAATAGC AGCTCAGGCT 1260

CTGTCTTCAG GAGCAGGTTC ACAAGAAACC AAGATCCCAA TCAGTCTAGT ACTAAGATTA 1320

CGGAATTCAA AAAAAGAACT AAATGATATT CGATTTGAAT TTACTCCTGG GAGAGATACA 1380

GCAGAGGGTG TCTCTCAGGA ACTCATTTCT GCCGGCCTCG TTGATGGAAG GGATTTAGTC 1440

ATAGTGGCAG CTAATTTGCA GAAGATTGTG GAAGAACCCC AGTCAAATCG ATCCGTCACC 1500

TTCAAACTGG CGTCTGGTGT CGAAGGCTCA GATATTCCTG ATGATGGTAA ACTAATAGGA 1560

TTTGCCCAGC TCAGCATCAG CTAA 1584

Domain Profile

S: 1     yelleeigkGalgkvylarekktgelvaikkinlekq.ekleelqkeisvlkklkhpniv  59

         yel+e+ig+Ga++ v++a++ +++e+vaik+inlek+ ++++el kei+++++++hpniv

Q: 17    YELQEVIGSGATAVVQAAYCAPKKEKVAIKRINLEKCqTSMDELLKEIQAMSQCHHPNIV  76

         99***********************************8899*******************

S: 60    eylesflkeeelwlvmeylagGslsdlvk......eelkselkEeqiayilrevlkaLey  113

         +y++sf++++elwlvm++l+gGs+ d++k      e+++  l+E +ia+il+evl++Ley

Q: 77    SYYTSFVVKDELWLVMKLLSGGSVLDIIKhivakgEHKNGVLDEATIATILKEVLEGLEY  136

         ********************************99999***********************

S: 114   lHskkviHrdikakniLlteegeVkLsdfgvaaqlek....trkk.rktvvgtpywmAPE  168

         lH++++iHrd+ka+niLl e+g+V+++dfgv+a l++    tr+k rkt+vgtp+wmAPE

Q: 137   LHKNGQIHRDVKAGNILLGEDGSVQIADFGVSAFLATggdiTRNKvRKTFVGTPCWMAPE  196

         ***********************************99999988899**************

S: 169   viaqeekgYdekaDiwslGItaielaegepPfkdleplkallkilkneppklksk.....  223

         v++q  +gYd kaDiws+GItaiela+g++P+++++p+k+l+++l+n+pp+l++

Q: 197   VMEQ-VRGYDFKADIWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPSLETGvqdke  255

         ***5.9*********************************************976677778

S: 224   ..kkfskefkefvekclqknpekRpsasellkhkFl  257

           kk++k+f+++++ clqk+pekRp+a+ell+hkF+

Q: 256   mlKKYGKSFRKMISLCLQKDPEKRPTAAELLRHKFF  291

         8899*******************************7

Domain Sequence
(FASTA)

YELQEVIGSG ATAVVQAAYC APKKEKVAIK RINLEKCQTS MDELLKEIQA MSQCHHPNIV 60

SYYTSFVVKD ELWLVMKLLS GGSVLDIIKH IVAKGEHKNG VLDEATIATI LKEVLEGLEY 120

LHKNGQIHRD VKAGNILLGE DGSVQIADFG VSAFLATGGD ITRNKVRKTF VGTPCWMAPE 180

VMEQVRGYDF KADIWSFGIT AIELATGAAP YHKYPPMKVL MLTLQNDPPS LETGVQDKEM 240

LKKYGKSFRK MISLCLQKDP EKRPTAAELL RHKFF 275

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0000287	; F:magnesium ion binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0007243	; P:intracellular protein kinase cascade
GO:0006979	; P:response to oxidative stress

KEGG

bta:526949

;

InterPros

IPR011009	; Kinase-like_dom.
IPR024678	; Kinase_OSR1/WNK_CCT.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.

Pfam

PF12202	; OSR1_C; 1.
PF00069	; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.

Prints

Created Date

20-Feb-2013