EKS-BOT-00071

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-BOT-00071

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDK	334.1	6.7E-100	4	288	285

Status

Unreviewed

Ensembl Protein

ENSBTAP00000020188

UniProt Accession

A6H7E6;

Protein Name

Protein Synonyms/Alias

CCRK protein;

Gene Name

CCRK

Gene Synonyms/Alias

CCRK; CDK20;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSBTAG00000015171	ENSBTAP00000020188	ENSBTAT00000020188

Organism

Bos taurus

Functional Description

Protein Length

346

Protein Sequence
(FASTA)

MEQYCILGRI GEGAHGIVFK AKHVETGEIV ALKKVALRRL EDGIPNQVLR EIKALQEIED 60

SQYVVQLKAV FPHGAGFVLA FEFMLSDLAE VVRHTQRPLA QAQVKSYLQM LLKGVAFCHA 120

NNIVHRDLKP ANLLISASGQ LKIADFGLAR VFSPDGNRLY THQVATRWYR APELLYGARQ 180

YDQGVDLWAV GCILGELLNG SPLFPGENDI EQLCCVLRIL GTPSPQVWPE ITELPDYNKI 240

SFKEQAPVPL EEVLPDASPQ ALDLLGRFLL YPPQQRISAS QALLHHYFFT APLPVHPSEL 300

PIPQRPGGPA PKAHPGPPHV HDFHVDRPLE ESLLNPELIR PFIPEG 346

Nucleotide Sequence
(FASTA)

ATGGAGCAGT ACTGCATCTT GGGGCGCATA GGGGAGGGTG CGCACGGCAT CGTCTTCAAA 60

GCCAAGCACG TGGAGACTGG AGAGATCGTT GCCCTCAAGA AGGTGGCCCT GCGGCGGCTG 120

GAGGATGGCA TCCCCAACCA GGTCCTACGG GAGATCAAGG CCCTGCAGGA GATCGAAGAC 180

AGTCAGTATG TTGTACAGCT GAAGGCCGTG TTCCCACACG GCGCAGGCTT TGTGCTGGCC 240

TTCGAGTTCA TGCTGTCAGA TCTGGCTGAG GTGGTGCGCC ACACCCAGAG GCCACTGGCC 300

CAGGCGCAGG TCAAGAGCTA CTTACAGATG CTGCTCAAGG GTGTCGCCTT CTGCCATGCC 360

AACAACATCG TGCATCGGGA CCTGAAGCCA GCCAACCTGC TTATCAGTGC TTCAGGCCAG 420

CTCAAGATAG CAGACTTTGG CCTGGCCCGG GTCTTTTCCC CAGATGGCAA CCGCCTCTAC 480

ACACACCAGG TGGCCACCAG GTGGTACCGA GCCCCCGAGC TCCTGTATGG TGCCCGCCAG 540

TACGATCAAG GTGTTGACCT CTGGGCTGTG GGCTGCATCC TGGGGGAGCT GCTGAACGGG 600

TCCCCCCTTT TCCCAGGAGA GAATGACATC GAACAGCTTT GTTGTGTGCT TCGAATCTTG 660

GGCACCCCCA GTCCTCAAGT CTGGCCGGAG ATCACTGAGC TGCCCGACTA CAACAAGATC 720

TCCTTTAAGG AGCAGGCACC TGTGCCCCTG GAGGAGGTGC TGCCCGATGC CTCTCCCCAG 780

GCCTTGGACC TGCTAGGGCG GTTCCTCCTC TACCCACCAC AACAGCGCAT CTCTGCCTCC 840

CAGGCCCTCC TGCACCACTA CTTCTTCACA GCTCCCCTGC CTGTCCACCC CTCGGAGCTG 900

CCGATCCCCC AGCGCCCAGG GGGACCTGCC CCGAAGGCCC ACCCAGGACC CCCCCATGTC 960

CATGACTTCC ACGTGGACCG GCCTCTCGAG GAGTCACTGT TGAACCCGGA GCTGATTCGG 1020

CCTTTCATCC CAGAGGGCTG A 1041

Domain Profile

S: 1     yeklekigeGtygkvykakdketgevvAlKkirlekekegvpitalrEisllkel.khkn  59

         y  l +igeG++g v+kak+ etge+vAlKk++l + ++g+p + lrEi+ l+e+ + ++

Q: 4     YCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGIPNQVLREIKALQEIeDSQY  63

         677899*************************************************77899

S: 60    ivkLlevvakdkkklyLvfefleqdLkkllkkkkkkklsleevkslllqlleglaylHsn  119

         +v+L+ v+  + + ++L fef+ +dL+++++++++  l +++vks+l++ll+g+a++H+n

Q: 64    VVQLKAVFP-HGAGFVLAFEFMLSDLAEVVRHTQR-PLAQAQVKSYLQMLLKGVAFCHAN  121

         *********.99*******************9999.************************

S: 120   kilHRDlKpqNlLiskegklklaDfGlarafssplkt.ytkevvTlwYraPelLlgakeY  178

         +i+HRDlKp+NlLis++g+lk+aDfGlar fs + ++ yt++v T+wYraPelL+ga++Y

Q: 122   NIVHRDLKPANLLISASGQLKIADFGLARVFSPDGNRlYTHQVATRWYRAPELLYGARQY  181

         *******************************8766644**********************

S: 179   stavDiWsvgcilaelltrkplfqgkseidqlerifkllgtpsekvwpevsklpeyk.ks  237

         ++ vD+W+vgcil ell+ +plf+g+++i+ql  ++++lgtps +vwpe+++lp+y+  s

Q: 182   DQGVDLWAVGCILGELLNGSPLFPGENDIEQLCCVLRILGTPSPQVWPEITELPDYNkIS  241

         *********************************************************88*

S: 238   fpkkkkkklkekvkklkekaldllekllaldpkkRisakealqhkyf  284

         f+++++  l+e++++++ +aldll ++l + p++Risa++al h+yf

Q: 242   FKEQAPVPLEEVLPDASPQALDLLGRFLLYPPQQRISASQALLHHYF  288

         **********************************************8

Domain Sequence
(FASTA)

YCILGRIGEG AHGIVFKAKH VETGEIVALK KVALRRLEDG IPNQVLREIK ALQEIEDSQY 60

VVQLKAVFPH GAGFVLAFEF MLSDLAEVVR HTQRPLAQAQ VKSYLQMLLK GVAFCHANNI 120

VHRDLKPANL LISASGQLKI ADFGLARVFS PDGNRLYTHQ VATRWYRAPE LLYGARQYDQ 180

GVDLWAVGCI LGELLNGSPL FPGENDIEQL CCVLRILGTP SPQVWPEITE LPDYNKISFK 240

EQAPVPLEEV LPDASPQALD LLGRFLLYPP QQRISASQAL LHHYF 285

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

bta:510920

;

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013