| Tag | Content |
|---|
| EKPD ID | EPS-BOT-00003 |
| Classification | | Group/Family | Score | E-Value | Start | End | Domain Length |
|---|
| DSP/aDSP | 190.4 | 1.6E-56 | 62 | 205 | 144 |
|
| Status | Reviewed |
| Ensembl Protein | ENSBTAP00000021830 |
| UniProt Accession | Q17QJ3; |
| Protein Name | Dual specificity protein phosphatase 26 |
| Protein Synonyms/Alias | |
| Gene Name | DUSP26 |
| Gene Synonyms/Alias | DUSP26; |
| Ensembl Information | |
| Organism | Bos taurus |
| Functional Description | Inactivates MAPK1 and MAPK3 which leads todephosphorylation of heat shock factor protein 4 and a reduction in its DNA-binding activity (By similarity). |
| Protein Length | 211 |
Protein Sequence
(FASTA) | | MCPGNWLWAS VTFMARFSRS GSRSPVRVRG ALEEPPAVQH PFLNVFELER LLYTGKTACN 60 | | HADEVWPGLY LGDQEIANNH RELRRLGITH VLNASHSRWR GTPEAYEGLG IRYLGVEAHD 120 | | SPAFDMSVHF QAAADFIHRA LSQPGGRILV HCAVGVSRSA TLVLAYLMLY HRLTLVEAIK 180 | | KVKDHRGIIP NRGFLRQLLA LDRRLRQGLE A 211 |
|
Nucleotide Sequence
(FASTA) | | ATGTGTCCCG GCAACTGGCT CTGGGCTTCG GTGACATTCA TGGCCCGCTT CTCCCGGAGC 60 | | GGCTCGAGGT CTCCAGTCCG CGTGAGAGGC GCCCTGGAGG AGCCGCCCGC CGTCCAGCAC 120 | | CCCTTCCTCA ACGTCTTCGA GTTGGAGAGG CTGCTGTACA CCGGGAAGAC CGCCTGTAAC 180 | | CACGCCGACG AGGTCTGGCC AGGCCTCTAC CTCGGAGACC AGGAAATAGC CAACAACCAC 240 | | CGGGAGCTGC GTCGCCTGGG CATCACGCAC GTCCTCAACG CCTCTCACAG CCGGTGGCGA 300 | | GGGACGCCCG AAGCCTACGA GGGGCTGGGC ATCCGCTACC TGGGTGTCGA GGCCCATGAC 360 | | TCGCCGGCCT TCGACATGAG TGTCCACTTC CAGGCAGCCG CTGACTTCAT CCACCGGGCG 420 | | CTGAGCCAGC CAGGAGGGAG GATCCTGGTG CACTGCGCCG TGGGAGTGAG CCGCTCGGCC 480 | | ACCCTGGTGC TGGCCTACCT CATGCTGTAC CACCGCCTCA CCCTTGTGGA GGCCATCAAG 540 | | AAAGTCAAGG ACCACCGAGG CATCATCCCC AACCGGGGCT TCCTGAGGCA GCTCCTGGCC 600 | | TTGGACCGCA GGCTGCGGCA GGGGCTGGAG GCGTGA 636 |
|
| Domain Profile | S: 2 vteilpglylgdqataldrreLsklgitvvinaslsvikvqviPeylikkgityknipvd 61 | +e++pglylgdq+ a+++reL++lgit+v+nas+s+++ ++Pe+++ gi+y++++++ | Q: 62 ADEVWPGLYLGDQEIANNHRELRRLGITHVLNASHSRWR--GTPEAYEGLGIRYLGVEAH 119 | 799************************************..******************* |
| S: 62 Dsdvtdllqyfdeaaefidea.kekggkvlvHCaaGvsRSatlvlaYLmkveglslsdAi 120 | Ds+++d++ +f++aa+fi++a +++gg++lvHCa+GvsRSatlvlaYLm ++ l+l++Ai | Q: 120 DSPAFDMSVHFQAAADFIHRAlSQPGGRILVHCAVGVSRSATLVLAYLMLYHRLTLVEAI 179 | *********************9999*********************************** |
| S: 121 eavkrkrpsiepnegfleQLlelekkl 147 | ++vk++r i+pn+gfl+QLl+l+++l | Q: 180 KKVKDHR-GIIPNRGFLRQLLALDRRL 205 | *******.9***************997 |
|
Domain Sequence
(FASTA) | | ADEVWPGLYL GDQEIANNHR ELRRLGITHV LNASHSRWRG TPEAYEGLGI RYLGVEAHDS 60 | | PAFDMSVHFQ AAADFIHRAL SQPGGRILVH CAVGVSRSAT LVLAYLMLYH RLTLVEAIKK 120 | | VKDHRGIIPN RGFLRQLLAL DRRL 144 |
|
| Keyword | Complete proteome; Cytoplasm; Golgi apparatus; Hydrolase; Nucleus; Protein phosphatase; Reference proteome. |
| Sequence Source | Ensembl |
| Orthology | |
| Gene Ontology | |
| KEGG | |
| InterPros | |
| Pfam | |
| SMARTs | |
| Prosites | |
| Prints | |
| Created Date | 20-Feb-2013 |