EPS-BOT-00035

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-BOT-00035

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	45.4	8.9E-12	68	221	154

Status

Unreviewed

Ensembl Protein

ENSBTAP00000026418

UniProt Accession

A6QQK2;

Protein Name

Protein Synonyms/Alias

MAP3K7IP1 protein;

Gene Name

MAP3K7IP1

Gene Synonyms/Alias

MAP3K7IP1; TAB1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSBTAG00000019828	ENSBTAP00000026418	ENSBTAT00000026418

Organism

Bos taurus

Functional Description

Protein Length

391

Protein Sequence
(FASTA)

MTRWLRRRAS SLSCPRVSLS TSCLLSIRRS SKDSRPWRRR SQEEPWLSWQ SFSTTGSTWP 60

MSLSCSNSAA GTNRALLCKS TVDGLQVTQL NVDHTTENED ELFRLSQLGL DAGKIKQVGV 120

ICGQESTRRI GDYKVKYGYT DVDLLSAAKS KPIIAEPEIH GAQPLDGVTG FLVLMSEGLY 180

KALEAAHGPG QANQEIAAMI DTEFAKQTSL DAVAQAVVDR VKRIHSDTFA SGGERAKFCP 240

RHEDMTLLVR NFGYPLGEMS QSAPSPAPAS GGRVYPVSVP YSSAQSTSKT SVTLSLVMPS 300

QGQLVNGAHS ASTLDEATPT LTNQSPTLTL QSTNTHTQSS SSSSDGGLFR SRPAHSLPPG 360

EDGRVEPYVD FAEFYRLWSV DHGEQSVVTA P 391

Nucleotide Sequence
(FASTA)

ATGACGCGCT GGCTGAGAAG GCGAGCCTCC AGTCTCAGCT GCCCGAGGGT GTCCCTCAGC 60

ACCAGCTGCC TCCTCAGTAT CAGAAGATCC TCGAAAGACT CAAGGCCTTG GAGAAGGAGA 120

TCTCAGGAGG AGCCATGGCT GTCGTGGCAG TCCTTCTCAA CAACAGGCTC TACGTGGCCA 180

ATGTCGCTCA GCTGCTCCAA TTCTGCTGCA GGTACAAACC GTGCACTTCT ATGCAAATCC 240

ACGGTGGACG GTCTGCAGGT GACGCAGCTG AACGTGGACC ACACCACAGA GAATGAGGAC 300

GAGCTTTTCC GGCTCTCGCA GCTGGGTTTG GATGCAGGAA AGATCAAGCA AGTGGGGGTC 360

ATCTGTGGGC AGGAGAGCAC CAGGCGCATT GGGGATTACA AGGTCAAGTA CGGGTACACT 420

GACGTCGACC TACTCAGTGC TGCCAAGTCC AAGCCGATCA TTGCAGAGCC TGAAATCCAC 480

GGTGCACAGC CCCTGGATGG GGTGACAGGC TTCCTGGTGC TGATGTCCGA GGGGCTGTAC 540

AAGGCCCTGG AGGCAGCCCA CGGGCCTGGG CAGGCCAACC AGGAGATCGC CGCCATGATC 600

GACACGGAGT TCGCCAAGCA GACCTCGCTT GACGCGGTGG CCCAGGCGGT GGTGGACCGG 660

GTGAAGCGGA TCCACAGCGA CACCTTTGCC AGTGGCGGGG AGCGTGCCAA GTTCTGTCCG 720

AGGCACGAGG ACATGACCCT GCTGGTGCGG AACTTTGGCT ACCCGCTGGG CGAGATGAGC 780

CAGTCCGCAC CCTCCCCAGC CCCAGCCTCT GGAGGACGCG TGTACCCCGT GTCCGTGCCT 840

TACTCGAGCG CCCAGAGCAC CAGCAAGACC AGCGTGACCC TGTCCCTCGT CATGCCCTCC 900

CAGGGCCAGC TGGTCAACGG GGCCCACAGC GCTTCCACCC TGGACGAGGC CACTCCCACC 960

CTCACCAACC AGAGCCCAAC CCTGACCCTG CAGTCCACCA ACACGCACAC CCAGAGCAGC 1020

AGCTCCAGCT CCGACGGGGG CCTTTTCCGC TCCCGGCCCG CCCACTCCCT CCCGCCTGGC 1080

GAGGATGGCC GCGTGGAGCC CTACGTGGAC TTTGCCGAGT TCTACCGCCT CTGGAGCGTG 1140

GACCATGGCG AGCAGAGTGT GGTGACGGCG CCGTAG 1176

Domain Profile

S: 120   anvGdSravLcrng.k...avelssdHkpsredEleRieeag...gsvilkdgaRvlGvL  172

         + +G  ra+Lc++  +   + +l +dH++++edEl R+++ g   g++ +     ++G

Q: 68    SAAGTNRALLCKSTvDglqVTQLNVDHTTENEDELFRLSQLGldaGKIKQVG--VICG-Q  124

         45899******9663366699*********************8777777664..4555.6

S: 173   avsRalGdlylk..............pyvtpePevtshrl.tsedefliLasDGlwdvvs  217

         + +R +Gd+++k              + +++ePe++  +  +  + fl+L s Gl++ ++

Q: 125   ESTRRIGDYKVKygytdvdllsaaksKPIIAEPEIHGAQPlDGVTGFLVLMSEGLYKALE  184

         9************************999*******98765155555***********986

S: 218   ........neeavslvrdvlekkeaeqeaakkLvkla  246

                 n+e+ +++     k+++++++a+ +v++

Q: 185   aahgpgqaNQEIAAMIDTEFAKQTSLDAVAQAVVDRV  221

         3333333366666666666667888888888887765

Domain Sequence
(FASTA)

SAAGTNRALL CKSTVDGLQV TQLNVDHTTE NEDELFRLSQ LGLDAGKIKQ VGVICGQEST 60

RRIGDYKVKY GYTDVDLLSA AKSKPIIAEP EIHGAQPLDG VTGFLVLMSE GLYKALEAAH 120

GPGQANQEIA AMIDTEFAKQ TSLDAVAQAV VDRV 154

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0003824	; F:catalytic activity
GO:0019209	; F:kinase activator activity
GO:0000185	; P:activation of MAPKKK activity
GO:0003007	; P:heart morphogenesis
GO:0001701	; P:in utero embryonic development
GO:0030324	; P:lung development
GO:0008152	; P:metabolic process
GO:0007179	; P:transforming growth factor beta receptor signaling pathway

KEGG

bta:519958

;

InterPros

IPR001932	; PP2C-like.
IPR015655	; Protein_Pase_2C.

Pfam

PF00481

; PP2C; 1.

SMARTs

SM00332

; PP2Cc; 1.

Prosites

Prints

Created Date

20-Feb-2013