EKS-CAF-00215

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CAF-00215

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDKL	482.6	3.6E-145	4	286	283

Status

Unreviewed

Ensembl Protein

ENSCAFP00000001432

UniProt Accession

E2RRT7;

Protein Name

Protein Synonyms/Alias

Gene Name

Cfa.45839

Gene Synonyms/Alias

Cfa.45839;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCAFG00000001010	ENSCAFP00000001432	ENSCAFT00000001557
ENSCAFG00000001010	ENSCAFP00000031613	ENSCAFT00000036258
ENSCAFG00000001010	ENSCAFP00000001429	ENSCAFT00000001554

Organism

Canis familiaris

Functional Description

Protein Length

542

Protein Sequence
(FASTA)

MEMYETLGKV GEGSYGTVMK CKHKDTGQIV AIKIFYEKPE KSVNKIATRE IKFLKQFRHE 60

NLVNLIEVFR QKKKIHLVFE FIDHTILDEL QHYCHGLESK RLRKYLFQIL RAIEYLHNNN 120

IIHRDIKPEN ILVSQSGITK LCDFGFARTL AAPGDIYTDY VATRWYRAPE LVLKDTSYGK 180

PVDIWALGCM IIEMATGNPY LPSSSDLDLL HKIVLKVGNL TPHLQNIFST SPIFAGVVLP 240

QVQHTKNARK KYPKLNGLLA DIVDACLQID PAERTSSTDL LHHEYFTRDG FIEKFIPELR 300

AKLLQEAKVN SFIKPKENSK ENELMKDERK TTYTNTLLST PVLGKEMERE KKPKEIKVRV 360

IKVKGGKGDI LEPNKIECEG RHCQQDAVEN AHSMSQDTKP VISEPLPSPV NPSTNSNGMK 420

DDPHAGGSMM MPPINLTSSN LMASNPNSNL SHPNSRLTER AKKRRTSSQS IGQVMSNYRQ 480

EDAGPIQSQM EKSVFNERTG QSDQMANGHK RKLNFSRSDR KEFHFPELPF TIQPKEVKGM 540

EG 542

Nucleotide Sequence
(FASTA)

ATGGAGATGT ATGAAACCCT CGGAAAAGTG GGAGAGGGAA GTTATGGAAC AGTCATGAAG 60

TGTAAACATA AGGATACTGG GCAGATAGTG GCCATTAAGA TATTTTACGA GAAACCGGAG 120

AAATCTGTCA ACAAAATTGC AACAAGAGAA ATAAAGTTTT TAAAGCAATT TCGTCATGAA 180

AACCTGGTCA ATCTGATTGA AGTTTTTAGA CAGAAAAAGA AAATTCATTT GGTGTTTGAA 240

TTTATTGACC ACACAATATT AGATGAGTTG CAACATTATT GTCATGGACT AGAGAGTAAA 300

CGACTTAGAA AATACCTCTT CCAGATCCTT CGAGCAATTG AATATCTTCA CAATAATAAC 360

ATCATTCATC GAGATATAAA ACCTGAGAAT ATTTTAGTAT CCCAGTCAGG AATTACTAAG 420

CTCTGTGATT TTGGTTTTGC ACGAACTCTA GCAGCTCCTG GGGACATTTA TACGGACTAT 480

GTGGCCACAC GCTGGTATAG AGCTCCAGAA TTAGTATTAA AAGATACTTC TTATGGAAAA 540

CCTGTAGATA TCTGGGCTTT GGGTTGTATG ATCATTGAGA TGGCCACTGG AAATCCCTAT 600

CTTCCTAGCA GTTCTGATTT GGATTTACTT CATAAAATTG TTTTAAAAGT AGGCAATTTG 660

ACACCTCACT TACAGAATAT CTTTTCTACG AGTCCCATTT TTGCTGGGGT GGTTCTTCCT 720

CAAGTTCAAC ACACCAAAAA TGCAAGAAAA AAATACCCAA AACTAAATGG ATTGTTGGCA 780

GATATAGTTG ACGCTTGTTT ACAAATTGAT CCTGCTGAGA GGACATCATC TACTGATCTT 840

TTGCATCATG AGTACTTTAC TAGAGATGGA TTTATTGAAA AATTCATACC AGAACTGAGA 900

GCTAAGTTAC TGCAAGAAGC AAAAGTCAAT TCATTCATAA AGCCAAAAGA GAATTCTAAA 960

GAGAACGAGC TTATGAAAGA TGAAAGAAAA ACAACTTATA CCAATACACT GCTAAGTACT 1020

CCAGTTTTGG GAAAGGAAAT GGAGAGAGAG AAAAAACCCA AGGAGATCAA AGTCAGAGTT 1080

ATTAAAGTCA AAGGAGGAAA AGGAGATATC TTAGAACCAA ACAAGATAGA GTGTGAAGGT 1140

AGACATTGTC AACAGGATGC CGTTGAAAAT GCTCATTCTA TGTCTCAAGA TACAAAACCT 1200

GTAATCAGTG AACCACTACC AAGCCCTGTC AATCCCAGCA CTAATTCTAA TGGCATGAAA 1260

GATGATCCAC ATGCTGGAGG TAGTATGATG ATGCCACCCA TCAATCTAAC TAGCAGTAAT 1320

TTGATGGCTT CAAATCCCAA TTCAAATCTT TCCCATCCAA ATTCAAGGTT GACTGAAAGA 1380

GCAAAAAAGA GACGTACCTC TTCACAATCT ATTGGACAGG TTATGTCTAA TTACAGGCAA 1440

GAGGATGCAG GTCCCATTCA AAGCCAAATG GAGAAAAGTG TATTTAATGA GCGAACAGGT 1500

CAAAGTGACC AAATGGCAAA TGGACACAAA AGAAAGCTGA ATTTTTCCAG ATCTGACAGG 1560

AAGGAATTCC ATTTCCCAGA ACTGCCTTTC ACAATACAGC CCAAGGAGGT GAAAGGAATG 1620

GAAGGCTAA 1629

Domain Profile

S: 1     yeklgkvGeGsyGvvlkcrnkdtgqivaikkfleseddkevkkialreikllkqlkhenl  60

         ye+lgkvGeGsyG+v+kc++kdtgqivaik f+e+++ k+v+kia+reik+lkq++henl

Q: 4     YETLGKVGEGSYGTVMKCKHKDTGQIVAIKIFYEKPE-KSVNKIATREIKFLKQFRHENL  62

         9***********************************9.9*********************

S: 61    vnllevfrrkkklylvfeyvdktvldelerypnGveeelvkkilyqilkaiefchknnii  120

         vnl+evfr+kkk++lvfe++d+t+ldel++y++G+e+++++k+l+qil+aie++h+nnii

Q: 63    VNLIEVFRQKKKIHLVFEFIDHTILDELQHYCHGLESKRLRKYLFQILRAIEYLHNNNII  122

         ************************************************************

S: 121   hrdikpenilisksgvvklcdfGfarllaapgdvytdyvatrwyrapellvgdtkyGksv  180

         hrdikpenil+s+sg++klcdfGfar+laapgd+ytdyvatrwyrapel+++dt+yGk+v

Q: 123   HRDIKPENILVSQSGITKLCDFGFARTLAAPGDIYTDYVATRWYRAPELVLKDTSYGKPV  182

         ************************************************************

S: 181   dvwaiGcllaelltGeplfpgksdvdqlykirktlGeliprhqkifsknevfaGvklpev  240

         d+wa+Gc+++e++tG+p++p++sd+d l+ki+ ++G+l+p+ q+ifs++++faGv+lp+v

Q: 183   DIWALGCMIIEMATGNPYLPSSSDLDLLHKIVLKVGNLTPHLQNIFSTSPIFAGVVLPQV  242

         ************************************************************

S: 241   edleslekkypklnevlldllkkclkldpaerlsceellkheyf  284

         +++++++kkypkln +l+d++ +cl++dpaer+s+++ll+heyf

Q: 243   QHTKNARKKYPKLNGLLADIVDACLQIDPAERTSSTDLLHHEYF  286

         *******************************************9

Domain Sequence
(FASTA)

YETLGKVGEG SYGTVMKCKH KDTGQIVAIK IFYEKPEKSV NKIATREIKF LKQFRHENLV 60

NLIEVFRQKK KIHLVFEFID HTILDELQHY CHGLESKRLR KYLFQILRAI EYLHNNNIIH 120

RDIKPENILV SQSGITKLCD FGFARTLAAP GDIYTDYVAT RWYRAPELVL KDTSYGKPVD 180

IWALGCMIIE MATGNPYLPS SSDLDLLHKI VLKVGNLTPH LQNIFSTSPI FAGVVLPQVQ 240

HTKNARKKYP KLNGLLADIV DACLQIDPAE RTSSTDLLHH EYF 283

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Cavia porcellus"; ?>Equus caballus"; ?>Felis catus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Vicugna pacos"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013