EPS-CAF-00033

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-CAF-00033

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	198.0	2.8E-58	59	316	258

Status

Unreviewed

Ensembl Protein

ENSCAFP00000006601

UniProt Accession

E2RDT6;

Protein Name

Protein Synonyms/Alias

Gene Name

PPM1N

Gene Synonyms/Alias

PPM1N;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCAFG00000004425	ENSCAFP00000006601	ENSCAFT00000007128

Organism

Canis familiaris

Functional Description

Protein Length

433

Protein Sequence
(FASTA)

MAAFARLLEH LLWPVCKKQE AEEEEEGRRS HHGPRSLLDA PRCVQRPHGG AAASCGLRFG 60

ASAVQGWRAH MEDAHCAWLE LPGLPPGWAF FAVLDGHGGA RAALFGARHL PGHVLEALGP 120

APGEPEGVRG ALRRAFLSAD ARLRALWPRG EPGGTTAVAL LVSPRFLYLA HCGDSRAMLS 180

RAGAVAFSTE DHRPLRPRER ERIHNAGGTI RRRRLEGSLA VSRALGDFAY KEAPGRPPEL 240

QLVSAEPEVT ALARQAEDEF LLLASDGVWD AMSGAALAGL VASRLRLGLA PELLCAQLLD 300

TCLCKGSLDN MTCILVCFPG APRPCEEAIK KELALDTALG HRVAALCSSA QEPPSLNTVF 360

WTLASEDIPD LPPGGGLHCK AAVIAEVYSQ LYQASGHERQ AGSPHEVADS CSSSSLMSQE 420

PNIPSGENSP GSQ 433

Nucleotide Sequence
(FASTA)

ATGGCTGCCT TTGCCCGCCT GCTGGAGCAT CTCCTCTGGC CAGTTTGCAA AAAACAGGAG 60

GCAGAGGAGG AGGAGGAGGG GCGCAGGTCT CACCACGGGC CTCGGTCGCT CCTGGACGCG 120

CCGCGATGCG TCCAGCGGCC GCACGGGGGT GCGGCGGCGT CTTGCGGCTT GCGCTTCGGG 180

GCCAGCGCTG TGCAGGGCTG GCGCGCGCAC ATGGAGGACG CGCACTGCGC TTGGCTCGAG 240

CTGCCCGGGC TACCCCCAGG CTGGGCATTC TTCGCGGTCC TCGACGGCCA CGGCGGGGCG 300

CGAGCTGCCC TATTCGGTGC GCGCCACCTG CCGGGCCACG TGCTAGAGGC TCTGGGCCCC 360

GCGCCGGGCG AGCCCGAGGG AGTGCGCGGG GCGCTACGCC GAGCCTTCCT GAGCGCGGAC 420

GCACGCCTGC GTGCGCTCTG GCCTCGTGGC GAGCCCGGGG GCACCACGGC CGTGGCTTTG 480

CTAGTCTCCC CGCGTTTTCT ATACTTGGCG CATTGCGGTG ACTCCCGAGC GATGCTGAGT 540

CGCGCCGGCG CCGTGGCCTT CAGCACCGAG GACCATCGGC CCCTCCGGCC CCGGGAACGG 600

GAGCGCATCC ACAACGCGGG GGGCACCATC CGCCGCCGGC GCCTCGAAGG CTCACTGGCA 660

GTATCCCGAG CGCTGGGCGA CTTTGCTTAC AAAGAGGCTC CGGGAAGGCC CCCTGAGCTG 720

CAGCTCGTTT CTGCGGAGCC TGAGGTCACC GCCCTGGCTC GCCAGGCTGA GGACGAATTC 780

CTGCTATTGG CCTCTGACGG TGTGTGGGAC GCGATGTCTG GCGCTGCCCT GGCGGGACTG 840

GTGGCGTCGC GCCTCCGCTT GGGCCTGGCC CCGGAGCTTC TCTGCGCGCA GCTATTGGAC 900

ACGTGTCTGT GCAAGGGCAG CCTGGACAAC ATGACCTGCA TCCTGGTCTG CTTCCCCGGG 960

GCCCCCAGGC CTTGTGAGGA GGCGATCAAG AAGGAGTTAG CGCTGGACAC AGCCCTGGGC 1020

CACAGGGTCG CCGCGCTGTG TTCCTCTGCT CAGGAGCCCC CCAGCCTGAA CACGGTTTTC 1080

TGGACTCTGG CCTCAGAGGA CATCCCAGAT TTACCTCCTG GGGGAGGGCT GCACTGCAAG 1140

GCGGCTGTCA TTGCTGAAGT TTATTCTCAG CTCTACCAAG CCTCAGGACA CGAAAGGCAG 1200

GCAGGATCTC CGCATGAGGT AGCAGACAGT TGCAGCTCTA GCAGCCTCAT GTCCCAGGAG 1260

CCCAACATCC CCAGTGGAGA GAATTCACCA GGTTCCCAGT AG 1302

Domain Profile

S: 3     vgvvsvngrrnemedavtsspnflkspekkdrlaffgvyDGhggsevakfcseklheila  62

         +g ++v+g+r +meda+ +  ++   p     +aff+v DGhgg ++a f + +l  ++

Q: 59    FGASAVQGWRAHMEDAHCAWLELPGLPP---GWAFFAVLDGHGGARAALFGARHLPGHVL  115

         7899*************87555555555...4****************************

S: 63    eelesseseerkvkkalakaFlstdeelkvleeksldidksGstavvalikdsklyvanv  122

         e l    +e + v+ al++aFls d +l    +   + ++ G+tav  l+++  ly a++

Q: 116   EALGPAPGEPEGVRGALRRAFLSADARL---RALWPRGEPGGTTAVALLVSPRFLYLAHC  172

         ****999*********************...555556999********************

S: 123   GdSravLcrngkavelssdHkpsredEleRieeaggsvilkdgaRvlGvLavsRalGdly  182

         GdSra+L+r g +   ++dH+p r++E+eRi +agg++ ++   R+ G+LavsRalGd+

Q: 173   GDSRAMLSRAGAVAFSTEDHRPLRPRERERIHNAGGTIRRR---RLEGSLAVSRALGDFA  229

         ************9**************************99...****************

S: 183   lk.........pyvtpePevtshrltsedefliLasDGlwdvvsneeavslvrdvlekke  233

         +k         ++v++ePevt   ++ edefl LasDG+wd +s  ++  lv ++l+ +

Q: 230   YKeapgrppelQLVSAEPEVTALARQAEDEFLLLASDGVWDAMSGAALAGLVASRLRLGL  289

         ************************************************************

S: 234   aeqeaakkLvklalargskdnvsaivv  260

         a++  + +L++++l +gs dn++ i+v

Q: 290   APELLCAQLLDTCLCKGSLDNMTCILV  316

         **********************99876

Domain Sequence
(FASTA)

FGASAVQGWR AHMEDAHCAW LELPGLPPGW AFFAVLDGHG GARAALFGAR HLPGHVLEAL 60

GPAPGEPEGV RGALRRAFLS ADARLRALWP RGEPGGTTAV ALLVSPRFLY LAHCGDSRAM 120

LSRAGAVAFS TEDHRPLRPR ERERIHNAGG TIRRRRLEGS LAVSRALGDF AYKEAPGRPP 180

ELQLVSAEPE VTALARQAED EFLLLASDGV WDAMSGAALA GLVASRLRLG LAPELLCAQL 240

LDTCLCKGSL DNMTCILV 258

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Felis catus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Macaca mulatta"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Nomascus leucogenys"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sorex araneus"; ?>

Gene Ontology

GO:0000287	; F:magnesium ion binding
GO:0030145	; F:manganese ion binding
GO:0004721	; F:phosphoprotein phosphatase activity
GO:0008152	; P:metabolic process

KEGG

InterPros

IPR001932	; PP2C-like.
IPR012911	; PP2C_C.
IPR015655	; Protein_Pase_2C.

Pfam

PF00481	; PP2C; 1.
PF07830	; PP2C_C; 1.

SMARTs

SM00331	; PP2C_SIG; 1.
SM00332	; PP2Cc; 1.

Prosites

Prints

Created Date

20-Feb-2013