EKS-CAF-00292

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CAF-00292

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TKL/STKR	327.0	1.2E-97	210	511	302

Status

Unreviewed

Ensembl Protein

ENSCAFP00000010309

UniProt Accession

E2RI46;

Protein Name

Protein Synonyms/Alias

Gene Name

AMHR2

Gene Synonyms/Alias

AMHR2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCAFG00000006934	ENSCAFP00000010309	ENSCAFT00000011129

Organism

Canis familiaris

Functional Description

Protein Length

561

Protein Sequence
(FASTA)

MLGTLGLWVL LPTAVQAPPS RRTCVFFEAP GVRGSTKTLG KLLDAGPGPP RVIRCLYSRC 60

CFGIWNLTQD QAQVEMQGCR DSDEPDCESP HCDLSPRAHP SPGSTLFTCS CGTDFCNANY 120

SHLPPPGNPG TPGSQGPQAI PGESIWMALV LLGLLVLLLL LLGSIILALR QRKACSVQGG 180

PEPEPEPEQE PEPDSGGDWS AELPELSELC FSQVIWEGGH TAVWAGQLRG RLVAIKAFSL 240

RAVAQFQAER AVYELPGLQH DHIVRFITAS RGGPGSPPCG PLLVLELHPK GSLCQYLTQH 300

TSDWGSSMRM ALSLAQGLAF LHEERWQDGQ YKPGIAHRDL SSQNVLVRED GSCAIGDLGL 360

ALVLPGLTQP PTWAPTQPRG PAAIMEAGTQ RYMAPELLDK TLDLQDWGTA LRQADVYSLA 420

LLLWEILSRC PDLRPDSRPP PFQLAYEAEL GSTPTTCELW TLAVEERRRP CIPSTWHSFT 480

TDPGSLRELL EDCWDADPEA RLTAECVQQR LAALAHPQEA QPFPESFAHG CPPLCPEDCL 540

SAPPTAIPPC RPQLDVCYFL V 561

Nucleotide Sequence
(FASTA)

ATGCTGGGGA CTCTGGGCCT TTGGGTACTA CTTCCCACAG CTGTGCAAGC ACCCCCAAGC 60

AGGCGGACCT GTGTGTTCTT TGAGGCCCCT GGAGTACGGG GAAGCACAAA GACACTGGGG 120

AAGCTGCTAG ATGCAGGACC AGGGCCCCCC AGGGTTATCC GCTGCCTCTA CAGCCGCTGC 180

TGTTTTGGGA TCTGGAACCT GACCCAAGAC CAGGCACAGG TGGAGATGCA AGGATGCCGA 240

GACAGTGATG AGCCAGACTG TGAGTCCCCC CACTGTGACC TGAGCCCCCG AGCCCACCCC 300

AGCCCCGGGT CCACTCTCTT CACCTGCTCC TGTGGCACTG ACTTCTGCAA TGCCAATTAC 360

AGCCATCTGC CTCCTCCAGG GAACCCTGGG ACCCCTGGCT CCCAGGGTCC CCAAGCTATC 420

CCAGGCGAGT CCATCTGGAT GGCGCTGGTG CTGCTGGGGC TGCTCGTCCT GCTGCTGCTG 480

CTGCTCGGCA GCATCATCTT GGCCCTGCGA CAGCGGAAGG CCTGCAGCGT TCAAGGTGGG 540

CCAGAGCCGG AGCCAGAGCC GGAGCAGGAG CCGGAGCCAG ACTCAGGCGG GGACTGGAGT 600

GCTGAGCTCC CCGAGCTGTC TGAGCTGTGT TTCTCCCAGG TAATCTGGGA AGGAGGCCAC 660

ACGGCCGTGT GGGCTGGGCA GCTGCGAGGC AGACTGGTGG CCATCAAGGC CTTCTCCCTG 720

AGGGCTGTGG CCCAGTTCCA AGCGGAGAGA GCGGTGTACG AACTGCCAGG CCTGCAGCAC 780

GACCACATTG TCCGCTTTAT CACCGCCAGC AGAGGGGGCC CTGGCTCCCC GCCCTGTGGG 840

CCCCTGCTGG TACTGGAACT GCATCCGAAG GGCTCCCTGT GCCAGTACTT GACCCAGCAC 900

ACCAGTGACT GGGGAAGTTC CATGCGGATG GCACTGTCCC TGGCGCAGGG CCTGGCATTT 960

CTCCATGAGG AGCGCTGGCA GGATGGCCAA TACAAACCAG GTATTGCCCA CCGCGATCTG 1020

AGCAGTCAGA ATGTGCTCGT TCGGGAGGAT GGGTCGTGTG CCATTGGAGA CCTTGGCCTT 1080

GCCTTGGTGC TCCCTGGCCT CACCCAGCCT CCCACCTGGG CCCCTACTCA ACCCCGAGGC 1140

CCAGCTGCCA TCATGGAGGC TGGCACCCAG AGGTACATGG CGCCGGAGCT CTTGGACAAG 1200

ACTCTGGACC TACAGGACTG GGGCACGGCC CTCCGACAAG CCGATGTTTA CTCTCTGGCT 1260

CTGCTCCTAT GGGAGATCCT GAGCCGCTGC CCAGATTTGA GGCCTGACAG CAGACCACCA 1320

CCTTTCCAAC TGGCCTATGA GGCAGAACTG GGTAGCACCC CCACCACCTG TGAGCTGTGG 1380

ACCTTGGCCG TAGAGGAGAG AAGGCGCCCC TGTATCCCAT CCACCTGGCA CTCCTTCACC 1440

ACAGACCCTG GCAGCCTGAG AGAGCTGCTA GAGGACTGTT GGGATGCAGA CCCCGAAGCA 1500

CGGCTGACAG CTGAGTGTGT ACAGCAGCGC CTGGCCGCCC TGGCCCATCC TCAAGAGGCC 1560

CAGCCCTTCC CAGAGAGCTT CGCCCATGGC TGCCCACCCC TCTGCCCAGA AGACTGTCTC 1620

TCAGCTCCTC CCACTGCCAT TCCCCCTTGT AGGCCTCAGC TGGATGTCTG CTACTTCCTT 1680

GTT 1683

Domain Profile

S: 2     klleligkGrygeVwkaklrgeevAvKifstedeaswkrEkeiyqtvllrhenilqfiaa  61

          ++++i +G +++Vw+++lrg+ vA+K+fs +  a++++E+++y+++ l+h++i++fi+a

Q: 210   CFSQVIWEGGHTAVWAGQLRGRLVAIKAFSLRAVAQFQAERAVYELPGLQHDHIVRFITA  269

         57899*******************************************************

S: 62    dk.keedsltelllvteyhekgsLsdyLkretldveellrlalslasGlahLHeeivgtk  120

          +    +     llv+e+h+kgsL++yL+++t+d+ +++r+alsla+Gla+LHee ++++

Q: 270   SRgGPGSPPCGPLLVLELHPKGSLCQYLTQHTSDWGSSMRMALSLAQGLAFLHEE-RWQD  328

         **77777889*********************************************.8999

S: 121   gkkKpaiaHRDlkskNilvkkdltcciaDlGLalkleeekee........ldlaansqvG  172

         g++Kp iaHRDl+s+N+lv++d++c+i+DlGLal l   ++         +  aa++++G

Q: 329   GQYKPGIAHRDLSSQNVLVREDGSCAIGDLGLALVLPGLTQPptwaptqpRGPAAIMEAG  388

         **********************************87776666688888888889******

S: 173   tkRYmaPEvleealnlkdfe.afkraDvYslgLvlWEvasRcee..vdeeveeyklpfee  229

         t+RYmaPE+l+++l+l+d+  a+++aDvYsl+L+lWE++sRc +  +d++ ++++l++e+

Q: 389   TQRYMAPELLDKTLDLQDWGtALRQADVYSLALLLWEILSRCPDlrPDSRPPPFQLAYEA  448

         *******************99***********************999*************

S: 230   vvgsdPsleemkevvvekklrPkipeawkkke.alkelsklleecWdadpeaRltalrvk  288

         ++gs+P++ e++++ ve++ rP ip++w++   +  +l++lle+cWdadpeaRlta++v+

Q: 449   ELGSTPTTCELWTLAVEERRRPCIPSTWHSFTtDPGSLRELLEDCWDADPEARLTAECVQ  508

         *****************************9886899************************

S: 289   krl  291

+rl

Q: 509   QRL  511

Domain Sequence
(FASTA)

CFSQVIWEGG HTAVWAGQLR GRLVAIKAFS LRAVAQFQAE RAVYELPGLQ HDHIVRFITA 60

SRGGPGSPPC GPLLVLELHP KGSLCQYLTQ HTSDWGSSMR MALSLAQGLA FLHEERWQDG 120

QYKPGIAHRD LSSQNVLVRE DGSCAIGDLG LALVLPGLTQ PPTWAPTQPR GPAAIMEAGT 180

QRYMAPELLD KTLDLQDWGT ALRQADVYSL ALLLWEILSR CPDLRPDSRP PPFQLAYEAE 240

LGSTPTTCEL WTLAVEERRR PCIPSTWHSF TTDPGSLREL LEDCWDADPE ARLTAECVQQ 300

RL 302

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Cavia porcellus"; ?>Equus caballus"; ?>Felis catus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Microcebus murinus"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>

Gene Ontology

GO:0016020	; C:membrane
GO:0005524	; F:ATP binding
GO:0005024	; F:transforming growth factor beta-activated receptor activity
GO:0007178	; P:transmembrane receptor protein serine/threonine kinase signaling pathway

KEGG

InterPros

IPR000472	; Activin_rcpt.
IPR015771	; Anti-muellerian_hrmn_rcpt_II.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.

Pfam

PF01064	; Activin_recp; 1.
PF00069	; Pkinase; 1.

SMARTs

Prosites

PS50011

; PROTEIN_KINASE_DOM; 1.

Prints

Created Date

20-Feb-2013