EKS-CAF-00092

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CAF-00092

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Atypical/PIKK	456.7	5.9E-137	2289	2615	327

Status

Unreviewed

Ensembl Protein

ENSCAFP00000039749

UniProt Accession

E2QXA4;

Protein Name

Protein Synonyms/Alias

Gene Name

ATR

Gene Synonyms/Alias

ATR;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCAFG00000007863	ENSCAFP00000039749	ENSCAFT00000049875
ENSCAFG00000007863	ENSCAFP00000011639	ENSCAFT00000012571

Organism

Canis familiaris

Functional Description

Protein Length

2640

Protein Sequence
(FASTA)

MGDHGLELAS MIPALRELGS ASPEEYNTVV QKPRQILCQF IDRILTDVNV VALELVKKTD 60

SQPTSVMLLD FIQHIMKSSP LMFVNVNGSQ GQNEAKGSCI EFSNWIITRL LRIAATPSCH 120

LLHKKICEVI CSLLFLFKSK SPAIFGVLTK ELLYLCEDVI CLHRKNAVGH FVEWPVVVSR 180

FLSQLDEHME YLQPAPLQFM NMQNLEFIEV TLLTVLIRII AIVFFRRQEL LLWRIGCVLL 240

EYGSSKTKSL AISLLTELFE LGGLPAQPAS TFFSSFLGLL KHLVEMDADQ LKLYEEPLSK 300

LIKTLFPFEA EAYRNIEPVY LNMLLENLCV MFEDGVLMRL KSDLLKAALC HLLQYFLKYV 360

PAGYESALQV RKVYVRNICK VLVDVLGFQV DAEYLLGPLY AALKMESMEI IEEVQCQIQQ 420

ENLSSNSDGI SAKRRRLSSS LNSSKRPPKQ TEEIKHVDMN KKSILWSALK QKAESLQIFL 480

EYNGLKNPVI ATLEGITIVL QLTALCTVHC SHHNMDWDCH QKCKKKPSVE ITWMSLDFYT 540

KVLKSCRSLL ESVQKPDLEA VIDKVVKIYD ALIYIHMKTS FEDHILEDLC GMLSLPWIHS 600

HSDDGSLKLT TFATNLLALS QRISDSYSPQ AQSRCVFLLT LFPRRIFLEW RTAIYSWALQ 660

SSHEVIRASC VNGFFILLQQ QNSCNRVPKI LIDKVKDDSD FVKREFASIL GQLVCTLHGM 720

FHLTSSLTEP FSEHGYTDLF CKNLKVASQH ECSSSQLKAS ICKPFLFLLR KKTPSPVKLA 780

FIDNLYHLCK HLDFREDETD VKTVLGTLLN LMEDPDKDVR VAFSGNIKHI LESLDSEDGF 840

IKELFVLRMK EAYTHAQISR NNELKDTLIL TTGDIGRAAK GDLVPFALLH LLHCLLSKSA 900

SVSGAAYTEI RALVAAKSVK LQNFFSQYKK PICQFLVESL HSSQMTALPS TPCQNAEMRK 960

QDVAHQREMA LNTLSEIANV FDFPDLNRFL TRTLQVLLPD LAAKASPAAS ALIRTLGKQL 1020

NVNRREILIN NFKYIFSHLV CSCSKDELER ALHYLKNETE IELGSLLRQD FQGLHNELLL 1080

RIGEHYQQVF NGLSILASFA SSDDPYQGPR EITSPELMAD YLQPKLLGIL AFFNMQLLSS 1140

SVGIEDKKMA LNSLMSLMKL MGPKHVSSVR VKMMTTLRTG LRFKDDFPEL CCRAWDCFVR 1200

CLDHAYLGSL LSHVIVALLP LIHIQPEETA AIFHYLIIEN RDAVQDFLHE IYFLPDHPEL 1260

KKIKAVLQEY RKETSESTDL QTTLQLSMKA IQHENVDVRI HALTSLKETL YKNQEKLIKY 1320

ATDSETVEPV ISQLVTVLLK GCQDANSQAR LLCGECLGEL GAIDPGRLDF STTESQGKDF 1380

TFVTGVEDSS FAFGLLMELT RAYLAYADNS RAQDSAAYAI QELLSIYDCR EMQTDGPGHQ 1440

LWRRFPEHVR EILEPHLNTR YKSSQKSTDW SEVKKPIYLS KLGNNFAEWS ASWAGYLITK 1500

VRHDLASKIF TCCSIMMKHD FKVTIYLLPH ILVYVLLGCN QEDQQEVYAE IMAVLKHDDQ 1560

HTISTQDSAS DLCQLSTQTV FSMLDHLTQW ARHKFQALNA EKFPQSKSNR DKIDSVASTA 1620

DYEDYQSVTR FLDLIPQDTL AVASFRSKAY TRAVMHFESF ITEKKQNIQE HLGFLQKLYA 1680

AMHEPDGVAG VSAIRKAEPS LKEQILEHES IGLLRDATAC YDRAIQLEPD QIIHYHGVVK 1740

SMLGLGQLST VITQVNGVHA NRSEWTDELN TYRVEAAWKL SQWDLVENYL AADGKSTTWS 1800

VRLGQLLLSA KKRDTTAFYD TLKLVRAEQI VPLSAASFER GSYQRGYEYI VRLHMLCELE 1860

HSIKPLFHQS PGDSSQEDSL NWVARLEMTQ NSYRAKEPIL ALRRALLSLN KRPDYNEMVG 1920

ECWLQSARVA RKAGHHQTAY NALLNAGESR LAELYVERAK WLWSKGDVHQ ALIVLQKGVE 1980

LCFPENKTPT ESKNMLIHGR AMLLVGRFME ETANFESNAV MKKYKDVTLF LPEWEDGHFY 2040

LAKYYDKLMP MVTDNKMEKQ GDLIRYIVLH FGRSLQYGNQ FIYQSMPRML SLWLDFGAKA 2100

YEWEKAGRSD RVQMRNDLAK INKVITEHTN HLAPYQFLTA FSQLISRICH SHDEVFVVLM 2160

EIIAKVFLAY PQQAMWMMTA VSKSSYPMRV NRCKEILNKA IHMKKSLEKF IGDATRLTDK 2220

LLELCNKPVD GSSSTLSMST HFKMLKKLVE EPTFSEILIP LQSVMIPTLP SIPGAHANHE 2280

PFPGHWAYIA SFDDMVEILA SLQKPKKISL KGSDGKFYIM MCKPKDDLRK DCRLMEFNSL 2340

INKCLRKDAE SRRRELHIRT YAVIPLNDEC GIIEWVNNTA GLRPILTKLY KEKGVYMTGK 2400

ELRQCMLPKA AALSEKLKVF REFLLPRHPP VFHEWFLRTF PDPTSWYSSR SAYCRSTAVM 2460

SMVGYILGLG DRHGENILFD SLTGECVHVD FNCLFNKGET FEVPEIVPFR LTHNMVNGMG 2520

PMGTEGLFRR ACEVTMRLMR DQREPLMSVL KTFLHDPLVE WSKPVKGHSK APLNETGEVV 2580

NEKAKTHVLD IEQRLQGVIK TRNRVTGLPL SIEGHVHYLI QEATDENLLC QMYLGWTPYM 2640

Nucleotide Sequence
(FASTA)

ATGGGCGACC ACGGCCTGGA GCTGGCGTCT ATGATCCCCG CTCTGCGGGA GTTGGGCAGT 60

GCCAGTCCAG AAGAATATAA TACAGTTGTA CAGAAGCCAA GACAAATTTT ATGTCAGTTC 120

ATTGACCGAA TACTTACAGA TGTAAATGTT GTTGCTCTAG AACTTGTAAA GAAAACTGAC 180

TCTCAGCCAA CCTCTGTGAT GTTGCTTGAT TTCATCCAAC ATATAATGAA GTCCTCCCCA 240

CTTATGTTTG TAAATGTGAA TGGAAGTCAA GGGCAAAATG AGGCCAAAGG CAGTTGTATT 300

GAATTCAGTA ATTGGATCAT AACGAGACTT CTGCGGATTG CAGCAACTCC ATCCTGTCAC 360

TTGTTACACA AGAAAATCTG TGAAGTTATC TGCTCATTAT TATTTCTTTT TAAAAGCAAG 420

AGCCCTGCAA TTTTTGGAGT ACTGACAAAG GAATTACTCT ATCTTTGTGA AGATGTGATT 480

TGCCTCCACA GAAAAAATGC AGTGGGACAC TTTGTGGAAT GGCCAGTGGT AGTTAGCCGA 540

TTTTTAAGTC AATTAGATGA ACACATGGAA TACTTACAGC CAGCTCCTTT GCAATTCATG 600

AACATGCAAA ATTTAGAATT TATTGAAGTC ACTTTATTAA CAGTTCTTAT TCGTATTATT 660

GCAATTGTGT TTTTTAGAAG GCAAGAACTC TTACTTTGGC GGATCGGTTG TGTTCTGCTA 720

GAATATGGTA GTTCAAAAAC TAAATCCTTA GCAATTAGCC TTTTAACTGA ACTCTTTGAG 780

CTTGGAGGAT TACCAGCACA ACCAGCCAGC ACTTTCTTCA GCTCATTTTT GGGATTATTA 840

AAACATCTTG TAGAAATGGA TGCTGACCAG TTGAAACTCT ATGAAGAACC ATTATCAAAG 900

CTGATAAAAA CACTATTCCC CTTTGAAGCA GAAGCTTATA GAAATATTGA GCCTGTCTAT 960

TTAAATATGC TGCTGGAAAA CCTCTGTGTC ATGTTTGAAG ATGGTGTGCT TATGCGGCTT 1020

AAGTCTGATT TGCTAAAAGC AGCTTTGTGC CACTTACTGC AGTATTTCCT TAAATATGTG 1080

CCAGCTGGGT ATGAATCTGC TTTACAAGTC AGGAAGGTTT ATGTGAGAAA CATTTGTAAA 1140

GTTCTTGTGG ATGTGCTTGG ATTTCAGGTG GATGCAGAGT ATTTGTTGGG CCCACTTTAT 1200

GCAGCCTTAA AAATGGAAAG TATGGAAATC ATTGAGGAGG TTCAGTGTCA AATTCAACAG 1260

GAAAACCTCA GCAGTAATAG TGATGGAATA TCAGCCAAAA GGCGTCGACT CAGCTCATCT 1320

CTGAACTCTT CCAAAAGACC ACCGAAACAG ACTGAGGAAA TTAAACATGT GGATATGAAC 1380

AAAAAGAGCA TTTTATGGAG TGCACTGAAA CAGAAAGCTG AATCCCTTCA GATTTTCCTT 1440

GAATACAATG GTCTAAAGAA TCCTGTTATT GCAACTTTAG AAGGAATCAC TATTGTCCTC 1500

CAACTCACTG CTCTATGTAC TGTTCATTGT TCGCATCATA ACATGGACTG GGACTGTCAT 1560

CAGAAATGTA AGAAGAAACC TTCAGTAGAG ATAACTTGGA TGTCTTTGGA TTTTTACACA 1620

AAAGTGCTTA AGAGCTGTAG AAGTTTGTTA GAATCTGTTC AGAAACCTGA CCTGGAGGCA 1680

GTTATTGATA AAGTGGTGAA AATATATGAT GCTCTGATTT ATATTCACAT GAAAACCTCA 1740

TTTGAAGATC ATATTCTAGA AGATTTATGT GGAATGCTCT CACTTCCATG GATTCATTCT 1800

CATTCTGATG ATGGGTCTTT AAAGTTGACC ACATTTGCCA CTAATCTTTT AGCATTAAGC 1860

CAGAGGATTT CAGATAGTTA CTCACCACAG GCACAGTCAC GGTGTGTGTT TCTTCTAACT 1920

TTGTTTCCAA GAAGAATATT CCTTGAATGG AGAACAGCAA TTTATAGCTG GGCCCTACAG 1980

AGCTCCCATG AAGTAATCCG GGCTAGTTGT GTTAATGGAT TTTTTATCTT ATTGCAGCAG 2040

CAAAATTCAT GTAACAGAGT TCCCAAGATT CTTATAGATA AAGTCAAAGA TGATTCTGAC 2100

TTTGTCAAGA GAGAATTTGC CTCTATCCTT GGTCAACTTG TCTGTACACT TCATGGCATG 2160

TTTCATTTGA CAAGTTCCTT AACAGAACCT TTCTCTGAAC ATGGATATAC TGACCTTTTC 2220

TGTAAAAATC TAAAAGTTGC ATCTCAACAT GAATGTTCAT CTTCTCAACT AAAAGCTTCC 2280

ATTTGCAAGC CATTCCTTTT CCTATTGAGA AAAAAAACAC CTAGTCCAGT GAAACTTGCT 2340

TTCATAGATA ATCTATATCA TCTTTGTAAG CATCTTGATT TTAGAGAAGA TGAAACAGAT 2400

GTGAAAACAG TTCTTGGAAC CTTATTAAAT TTAATGGAAG ATCCAGACAA GGATGTTAGA 2460

GTGGCTTTTA GTGGAAATAT CAAGCATATA TTGGAATCCT TAGACTCTGA GGATGGATTT 2520

ATAAAAGAGC TTTTTGTCTT AAGAATGAAG GAAGCATATA CACATGCTCA AATCTCAAGA 2580

AATAATGAGT TGAAGGATAC CTTGATTCTT ACAACAGGGG ATATTGGAAG AGCAGCAAAA 2640

GGAGATTTGG TACCTTTTGC ACTTTTGCAC TTATTGCATT GTTTATTATC CAAGTCAGCA 2700

TCTGTCTCTG GAGCAGCATA TACAGAAATC AGAGCTCTAG TTGCAGCTAA GAGTGTTAAA 2760

CTACAAAACT TTTTCAGCCA GTATAAGAAA CCCATCTGTC AGTTTTTAGT AGAGTCCCTC 2820

CATTCCAGTC AGATGACAGC GCTTCCTAGT ACTCCGTGCC AGAATGCTGA GATGCGAAAA 2880

CAAGATGTGG CTCACCAGAG AGAAATGGCT TTAAATACCT TGTCTGAAAT TGCCAATGTT 2940

TTTGACTTTC CTGATCTTAA TCGTTTCCTT ACTAGGACAT TACAAGTTCT GCTACCTGAC 3000

CTTGCTGCCA AAGCAAGCCC TGCAGCTTCT GCTCTCATTC GAACTTTAGG AAAACAATTA 3060

AATGTCAATC GTAGAGAGAT TTTAATAAAT AACTTCAAAT ATATTTTTTC TCATTTGGTC 3120

TGTTCCTGTT CCAAGGATGA ATTAGAACGG GCCCTTCATT ATCTAAAGAA TGAAACAGAA 3180

ATTGAACTGG GGAGTCTATT GAGACAAGAT TTCCAAGGAT TGCATAATGA ATTATTGCTA 3240

CGTATTGGAG AACACTATCA ACAGGTTTTC AATGGTTTGT CAATACTTGC CTCATTTGCA 3300

TCTAGTGATG ATCCATATCA GGGCCCCAGA GAGATCACAT CACCTGAACT AATGGCTGAT 3360

TATTTGCAAC CTAAGTTGTT GGGCATTTTG GCTTTTTTTA ACATGCAGTT ACTAAGCTCC 3420

AGTGTTGGCA TTGAAGATAA GAAAATGGCT TTGAACAGTT TGATGTCTTT GATGAAGTTG 3480

ATGGGACCAA AACACGTCAG CTCCGTGAGG GTGAAGATGA TGACCACACT AAGAACTGGC 3540

CTGAGATTCA AGGATGATTT TCCTGAATTG TGTTGCAGAG CTTGGGATTG CTTTGTTCGT 3600

TGCCTGGATC ATGCTTATCT TGGTTCCCTT CTCAGTCATG TGATAGTAGC TTTGTTACCT 3660

CTCATACACA TCCAGCCTGA AGAAACTGCT GCTATATTTC ACTACCTCAT AATTGAAAAC 3720

AGGGATGCTG TACAAGATTT TCTTCATGAA ATATATTTTT TACCTGATCA TCCAGAATTA 3780

AAAAAGATAA AAGCAGTTCT ACAGGAGTAC AGAAAGGAGA CCTCTGAGAG TACAGATCTT 3840

CAGACAACTC TTCAACTATC CATGAAAGCA ATTCAGCATG AAAATGTAGA TGTTCGTATT 3900

CATGCTCTTA CGAGCTTGAA GGAAACTTTG TATAAAAATC AGGAAAAGCT GATAAAATAT 3960

GCAACAGATA GTGAAACAGT GGAACCTGTT ATCTCACAGT TGGTGACAGT GCTTTTGAAA 4020

GGTTGCCAAG ATGCAAACTC TCAAGCTCGG TTGCTCTGTG GGGAGTGTTT AGGGGAACTG 4080

GGGGCAATAG ATCCAGGTCG ACTAGATTTC TCAACAACTG AAAGCCAAGG GAAAGATTTT 4140

ACATTTGTGA CGGGAGTAGA AGATTCAAGC TTTGCCTTTG GATTATTGAT GGAACTAACT 4200

AGAGCTTACC TTGCATATGC AGATAACAGC CGGGCTCAAG ATTCAGCTGC TTATGCCATT 4260

CAGGAGTTAC TTTCTATTTA TGACTGCAGA GAGATGCAGA CCGATGGTCC AGGTCACCAA 4320

TTGTGGAGGA GATTTCCTGA GCATGTTCGG GAAATCCTGG AACCTCATCT AAATACTAGA 4380

TATAAGAGCT CTCAGAAGTC AACAGATTGG TCTGAAGTAA AGAAGCCAAT TTACTTAAGT 4440

AAATTAGGTA ATAACTTTGC AGAATGGTCA GCATCTTGGG CAGGTTATCT TATAACAAAG 4500

GTTCGGCATG ATCTTGCCAG TAAAATCTTC ACTTGCTGTA GCATTATGAT GAAACATGAT 4560

TTCAAGGTGA CCATCTATCT TCTTCCACAT ATTCTAGTAT ATGTCTTGTT GGGTTGTAAT 4620

CAAGAAGATC AGCAAGAGGT TTATGCAGAA ATTATGGCAG TTCTAAAGCA TGATGATCAG 4680

CATACCATAA GTACCCAAGA CAGTGCATCT GATCTGTGTC AACTCAGTAC ACAGACTGTG 4740

TTCTCCATGC TTGACCATCT AACACAATGG GCAAGGCACA AATTTCAGGC ACTGAATGCA 4800

GAGAAATTTC CACAAAGCAA ATCAAACAGA GATAAGATAG ACTCAGTAGC ATCTACGGCG 4860

GATTATGAAG ACTATCAGAG TGTAACTCGT TTTCTAGACC TTATACCTCA GGATACCCTC 4920

GCAGTAGCTT CCTTTCGCTC CAAAGCATAC ACACGAGCTG TAATGCACTT TGAATCATTT 4980

ATTACAGAAA AGAAACAAAA TATTCAAGAG CATCTTGGAT TTTTACAGAA ATTGTATGCT 5040

GCTATGCATG AACCGGATGG AGTGGCTGGA GTAAGTGCAA TTCGAAAGGC AGAACCATCT 5100

TTGAAAGAAC AGATCCTTGA ACATGAAAGT ATTGGCTTAC TGAGGGATGC TACTGCTTGT 5160

TATGACAGGG CTATTCAGCT AGAACCAGAC CAGATCATTC ATTATCATGG TGTAGTGAAG 5220

TCCATGTTAG GTCTTGGTCA GTTGTCTACT GTAATCACTC AGGTGAATGG AGTGCATGCT 5280

AACAGATCTG AATGGACAGA TGAATTAAAC ACATATAGAG TGGAAGCAGC CTGGAAATTG 5340

TCACAGTGGG ATTTGGTGGA AAACTATTTG GCAGCAGATG GGAAATCTAC AACATGGAGT 5400

GTCAGACTGG GACAGTTACT ATTATCAGCC AAGAAAAGAG ATACCACAGC TTTTTATGAC 5460

ACACTGAAAC TAGTGAGAGC AGAACAAATT GTACCTCTTT CAGCTGCAAG CTTTGAAAGA 5520

GGCTCTTATC AACGAGGATA TGAATATATT GTAAGATTGC ACATGTTGTG TGAGTTGGAG 5580

CATAGCATCA AACCACTCTT TCACCAGTCG CCAGGTGACA GTTCTCAAGA AGATTCTCTC 5640

AACTGGGTAG CTCGACTAGA AATGACACAA AATTCCTACA GAGCTAAGGA GCCCATCCTG 5700

GCTCTCCGGA GAGCTTTATT AAGCCTCAAC AAAAGACCAG ATTACAATGA AATGGTTGGA 5760

GAATGTTGGC TACAGAGTGC CAGAGTAGCT AGAAAGGCTG GTCACCACCA GACAGCCTAC 5820

AATGCTCTCC TTAATGCTGG AGAATCAAGA CTTGCTGAAC TATATGTGGA GAGGGCAAAG 5880

TGGCTATGGT CCAAGGGTGA TGTTCACCAG GCACTAATTG TTCTTCAGAA GGGTGTTGAA 5940

TTATGTTTTC CTGAAAATAA AACCCCAACC GAGAGTAAGA ACATGTTAAT CCATGGTCGA 6000

GCTATGCTAC TAGTGGGCCG ATTTATGGAA GAAACAGCTA ACTTTGAAAG CAATGCAGTT 6060

ATGAAAAAAT ACAAGGATGT GACCTTGTTC TTGCCAGAGT GGGAGGATGG GCATTTTTAC 6120

CTTGCCAAGT ACTATGACAA ATTGATGCCC ATGGTCACAG ACAACAAAAT GGAAAAGCAA 6180

GGTGATCTCA TTCGGTATAT AGTTCTTCAT TTTGGCAGAT CTCTACAATA TGGAAATCAA 6240

TTCATATATC AGTCAATGCC ACGAATGTTA TCACTATGGC TTGATTTTGG TGCTAAGGCA 6300

TACGAATGGG AAAAAGCTGG CCGTTCTGAT CGTGTACAAA TGAGAAACGA TTTAGCCAAA 6360

ATAAACAAGG TTATCACAGA GCACACAAAT CACTTAGCAC CATATCAGTT TTTGACTGCT 6420

TTTTCACAGT TGATCTCTCG AATTTGTCAT TCTCATGATG AAGTTTTTGT TGTCTTGATG 6480

GAAATTATAG CCAAAGTGTT TCTGGCCTAT CCTCAACAAG CAATGTGGAT GATGACAGCT 6540

GTGTCAAAGT CTTCTTATCC CATGCGTGTG AACAGATGCA AGGAAATCCT AAATAAAGCT 6600

ATTCATATGA AAAAATCCTT AGAAAAATTT ATTGGAGATG CAACTCGCCT AACAGATAAG 6660

CTTTTGGAAT TGTGCAATAA ACCGGTGGAT GGAAGTAGTT CCACATTAAG CATGAGCACT 6720

CATTTTAAAA TGCTTAAAAA GCTGGTGGAA GAACCAACAT TTAGTGAAAT TCTCATTCCT 6780

TTACAATCAG TCATGATACC TACTCTTCCA TCAATTCCGG GTGCTCACGC TAACCATGAG 6840

CCATTTCCTG GGCATTGGGC CTATATTGCA AGCTTTGATG ATATGGTGGA AATTCTTGCT 6900

TCTCTTCAGA AACCAAAGAA GATCTCTTTG AAAGGATCAG ATGGAAAGTT CTACATCATG 6960

ATGTGTAAGC CAAAAGATGA CCTGAGAAAG GATTGTAGGC TAATGGAATT CAATTCCTTG 7020

ATTAATAAGT GTTTAAGAAA AGATGCAGAA TCTCGTAGAA GAGAACTTCA TATCCGAACA 7080

TATGCAGTTA TTCCCCTGAA TGATGAATGT GGAATTATTG AATGGGTTAA CAACACTGCT 7140

GGCTTGAGAC CTATTTTGAC CAAACTTTAT AAGGAAAAGG GAGTTTATAT GACAGGAAAA 7200

GAACTTCGGC AGTGTATGCT ACCAAAAGCT GCAGCTTTGT CTGAAAAACT CAAAGTATTC 7260

CGAGAATTTC TCCTACCCAG ACATCCTCCC GTTTTTCATG AATGGTTTCT GAGGACATTC 7320

CCTGATCCTA CATCATGGTA CAGTAGCAGA TCAGCATACT GCCGTTCTAC TGCAGTGATG 7380

TCAATGGTTG GTTATATCCT GGGGCTTGGA GACCGTCATG GTGAAAACAT TCTCTTTGAT 7440

TCTCTAACTG GTGAATGTGT ACATGTGGAT TTCAACTGTC TTTTCAATAA GGGAGAAACC 7500

TTTGAAGTTC CAGAAATTGT TCCATTTCGA CTGACTCATA ATATGGTTAA TGGAATGGGT 7560

CCTATGGGAA CAGAAGGTCT TTTTCGAAGA GCTTGTGAAG TTACAATGAG GCTGATGCGA 7620

GATCAAAGAG AGCCTTTAAT GAGTGTCTTA AAAACTTTTC TACATGATCC TCTTGTGGAA 7680

TGGAGTAAAC CAGTGAAAGG ACACTCCAAA GCACCACTGA ATGAAACTGG GGAGGTTGTC 7740

AATGAAAAGG CCAAGACCCA TGTTCTTGAC ATCGAGCAGC GACTGCAAGG TGTAATCAAG 7800

ACCCGAAATA GAGTGACAGG GCTGCCATTA TCTATTGAAG GACATGTACA TTACCTTATA 7860

CAAGAAGCTA CTGATGAAAA CTTACTGTGT CAAATGTACC TTGGTTGGAC TCCATATATG 7920

TGA 7923

Domain Profile

S: 1     iagfderveilaskqkpkklllrGsdgkeypyLvkgkeDlrqdervlqlfslvNtlLakd  60

         ia+fd++veilas+qkpkk++l+Gsdgk+y++++k+k+Dlr+d+r+++++sl+N++L+kd

Q: 2289  IASFDDMVEILASLQKPKKISLKGSDGKFYIMMCKPKDDLRKDCRLMEFNSLINKCLRKD  2348

         89**********************************************************

S: 61    ketsrrkLkirtykVvplstrsgliewventvsLkellkklvekkavlldqpisyrykdl  120

         +e++rr+L+irty+V+pl++++g+iewv+nt++L+ +l+kl+++k+v++        + +

Q: 2349  AESRRRELHIRTYAVIPLNDECGIIEWVNNTAGLRPILTKLYKEKGVYM--------TGK  2400

         *************************************************........599

S: 121   stvqarkpklkhlklslevfkevlenlvpkdllkklllekfpspeewfelrkaytrslAv  180

         + +q++ pk+++l+++l+vf+e+l +++p+ ++++++l++fp+p++w+++r+ay+rs+Av

Q: 2401  ELRQCMLPKAAALSEKLKVFREFLLPRHPP-VFHEWFLRTFPDPTSWYSSRSAYCRSTAV  2459

         *****************************8.*****************************

S: 181   islvgyiLgLgdrhlenllidqetgevvhidfgvafekaktqlkvpekvPFRLTrnivna  240

         +s+vgyiLgLgdrh en+l+d+ tge+vh+df++ f+k++t ++vpe+vPFRLT+n+vn+

Q: 2460  MSMVGYILGLGDRHGENILFDSLTGECVHVDFNCLFNKGET-FEVPEIVPFRLTHNMVNG  2518

         *****************************************.******************

S: 241   lgvtgveGvfrasceavlrvlreskeklltiLevflydplvdwkk.....kkktsketee  295

         +g++g+eG+fr++ce ++r++r+++e l+++L++fl+dplv+w+k     +k++ +et+e

Q: 2519  MGPMGTEGLFRRACEVTMRLMRDQREPLMSVLKTFLHDPLVEWSKpvkghSKAPLNETGE  2578

         *************************************************99*********

S: 296   elaekakaealkikkllskvekaenavatrdllllee  332

         +++ekak++ l+i+++l++v k++n+v+ ++l+++++

Q: 2579  VVNEKAKTHVLDIEQRLQGVIKTRNRVTGLPLSIEGH  2615

         ********************************99987

Domain Sequence
(FASTA)

IASFDDMVEI LASLQKPKKI SLKGSDGKFY IMMCKPKDDL RKDCRLMEFN SLINKCLRKD 60

AESRRRELHI RTYAVIPLND ECGIIEWVNN TAGLRPILTK LYKEKGVYMT GKELRQCMLP 120

KAAALSEKLK VFREFLLPRH PPVFHEWFLR TFPDPTSWYS SRSAYCRSTA VMSMVGYILG 180

LGDRHGENIL FDSLTGECVH VDFNCLFNKG ETFEVPEIVP FRLTHNMVNG MGPMGTEGLF 240

RRACEVTMRL MRDQREPLMS VLKTFLHDPL VEWSKPVKGH SKAPLNETGE VVNEKAKTHV 300

LDIEQRLQGV IKTRNRVTGL PLSIEGH 327

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011989	; ARM-like.
IPR016024	; ARM-type_fold.
IPR003152	; FATC.
IPR021133	; HEAT_type_2.
IPR011009	; Kinase-like_dom.
IPR000403	; PI3/4_kinase_cat_dom.
IPR018936	; PI3/4_kinase_CS.
IPR003151	; PIK-rel_kinase_FAT.
IPR014009	; PIK_FAT.
IPR011990	; TPR-like_helical.
IPR012993	; UME.

Pfam

PF02259	; FAT; 1.
PF02260	; FATC; 1.
PF00454	; PI3_PI4_kinase; 1.
PF08064	; UME; 1.

SMARTs

SM00146	; PI3Kc; 1.
SM00802	; UME; 1.

Prosites

PS51189	; FAT; 1.
PS51190	; FATC; 1.
PS50077	; HEAT_REPEAT; 1.
PS00916	; PI3_4_KINASE_2; 1.
PS50290	; PI3_4_KINASE_3; 1.

Prints

Created Date

20-Feb-2013