EPS-CAF-00071

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-CAF-00071

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPP/PP1	413.5	1.4E-124	58	251	194

Status

Unreviewed

Ensembl Protein

ENSCAFP00000030520

UniProt Accession

E2QXE0;

Protein Name

Serine/threonine-protein phosphatase

Protein Synonyms/Alias

Gene Name

Cfa.451

Gene Synonyms/Alias

Cfa.451;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCAFG00000008515	ENSCAFP00000030520	ENSCAFT00000035276

Organism

Canis familiaris

Functional Description

Protein Length

337

Protein Sequence
(FASTA)

MADIDKLNID SIIQRLLEVR GSKPGKNVQL QENEIRGLCL KSREIFLSQP ILLELEAPLK 60

ICGDIHGQYY DLLRLFEYGG FPPESNYLFL GDYVDRGKQS LETICLLLAY KIKYPENFFL 120

LRGNHECASI NRIYGFYDEC KRRYNIKLWK TFTDCFNCLP IAAIVDEKIF CCHGGLSPDL 180

QSMEQIRRIM RPTDVPDQGL LCDLLWSDPD KDVLGWGEND RGVSFTFGAE VVAKFLHKHD 240

LDLICRAHQV VEDGYEFFAK RQLVTLFSAP NYCGEFDNAG AMMSVDETLM CSFQILKPAE 300

KKKPNATRPV TPPRVTSGLN PSIQKASNYR NNTVLYE 337

Nucleotide Sequence
(FASTA)

ATGGCGGATA TAGATAAACT CAACATCGAC AGCATCATCC AACGGCTGCT GGAAGTGAGA 60

GGGTCCAAGC CTGGTAAGAA TGTCCAGCTA CAGGAAAATG AAATCCGAGG ACTGTGCTTA 120

AAGTCCCGAG AGATCTTTCT CAGTCAGCCT ATCCTACTAG AACTTGAAGC ACCACTCAAA 180

ATATGTGGTG ATATCCATGG GCAATACTAT GATTTGCTTC GACTTTTCGA GTACGGTGGT 240

TTCCCGCCAG AAAGCAACTA CCTGTTTCTT GGGGACTATG TGGACAGGGG GAAGCAGTCA 300

TTGGAGACTA TCTGCCTCTT ACTGGCTTAC AAAATCAAAT ATCCCGAGAA TTTTTTTCTT 360

CTCAGAGGAA ACCATGAATG TGCCAGCATC AATAGAATTT ATGGATTTTA CGATGAATGT 420

AAAAGAAGAT ATAACATTAA ACTATGGAAA ACTTTCACAG ACTGCTTTAA CTGTTTACCG 480

ATAGCAGCCA TCGTGGATGA GAAGATATTC TGCTGTCATG GAGGTTTATC ACCAGATCTT 540

CAATCTATGG AGCAGATTCG GCGAATTATG CGACCAACTG ATGTACCAGA TCAAGGTCTT 600

CTTTGTGATC TTTTGTGGTC TGACCCCGAT AAAGATGTCT TAGGCTGGGG TGAAAATGAC 660

AGAGGAGTGT CCTTCACATT TGGTGCAGAA GTGGTTGCAA AATTTCTCCA TAAGCATGAT 720

TTGGATCTTA TATGTAGAGC CCATCAGGTG GTTGAAGATG GATATGAATT TTTTGCAAAG 780

AGGCAGTTGG TCACTCTGTT TTCTGCACCC AATTATTGTG GAGAGTTTGA CAATGCAGGT 840

GCCATGATGA GTGTGGACGA AACTCTAATG TGTTCTTTTC AGATTTTAAA GCCTGCAGAG 900

AAAAAGAAGC CGAATGCCAC GAGACCTGTA ACACCTCCAA GGGTTACATC AGGCCTGAAC 960

CCGTCCATTC AGAAAGCTTC AAATTATAGA AACAATACTG TTCTATACGA GTGA 1014

Domain Profile

S: 1     pvkicgdihgqykdllrlfeyggfppeanylflgdyvdrgkqsleticlllaykikypen  60

         p+kicgdihgqy+dllrlfeyggfppe+nylflgdyvdrgkqsleticlllaykikypen

Q: 58    PLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPEN  117

         89**********************************************************

S: 61    ffllrgnhesasinriygfydeckrrynvklwktftdcfnclpvaaiidekilcvhggls  120

         ffllrgnhe+asinriygfydeckrryn+klwktftdcfnclp+aai+deki+c+hggls

Q: 118   FFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLS  177

         ************************************************************

S: 121   pdlksleqirrikrptdvpdegllcdllwsdpdkdvkgwgendrgvsftfgadvvakflk  180

         pdl+s+eqirri+rptdvpd+gllcdllwsdpdkdv gwgendrgvsftfga+vvakfl+

Q: 178   PDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVLGWGENDRGVSFTFGAEVVAKFLH  237

         ************************************************************

S: 181   khdldlicrahqvv  194

         khdldlicrahqvv

Q: 238   KHDLDLICRAHQVV  251

         *************8

Domain Sequence
(FASTA)

PLKICGDIHG QYYDLLRLFE YGGFPPESNY LFLGDYVDRG KQSLETICLL LAYKIKYPEN 60

FFLLRGNHEC ASINRIYGFY DECKRRYNIK LWKTFTDCFN CLPIAAIVDE KIFCCHGGLS 120

PDLQSMEQIR RIMRPTDVPD QGLLCDLLWS DPDKDVLGWG ENDRGVSFTF GAEVVAKFLH 180

KHDLDLICRA HQVV 194

Keyword

Complete proteome; Hydrolase; Iron; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005741	; C:mitochondrial outer membrane
GO:0070688	; C:MLL5-L complex
GO:0005730	; C:nucleolus
GO:0072357	; C:PTW/PP1 phosphatase complex
GO:0004722	; F:protein serine/threonine phosphatase activity
GO:0006470	; P:protein dephosphorylation
GO:0046822	; P:regulation of nucleocytoplasmic transport

KEGG

InterPros

IPR004843	; Metallo_PEstase_dom.
IPR006186	; Ser/Thr-sp_prot-phosphatase.

Pfam

PF00149

; Metallophos; 1.

SMARTs

SM00156

; PP2Ac; 1.

Prosites

PS00125

; SER_THR_PHOSPHATASE; 1.

Prints

PR00114

; STPHPHTASE.

Created Date

20-Feb-2013