EPS-CAF-00020

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-CAF-00020

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
DSP/aDSP	70.4	1.7E-19	87	200	114

Status

Unreviewed

Ensembl Protein

ENSCAFP00000012927

UniProt Accession

E2RSE3;

Protein Name

Protein Synonyms/Alias

Gene Name

DUSP11

Gene Synonyms/Alias

DUSP11;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCAFG00000008797	ENSCAFP00000012927	ENSCAFT00000013972

Organism

Canis familiaris

Functional Description

Protein Length

332

Protein Sequence
(FASTA)

MSQWHHARGG WGQGHVFSGR RSAKKKRGNH VPERWKDYLP IGQRMPGTRF IAFKVPLKKS 60

FEKNLAPEER FSPLDLFNKI QNQNEELGLI IDLTYTHRYY KPEDLPETIP HLKIYTIGHQ 120

VPDDDTIFKF KCAVNEFLKE NTDNDKLIGV HCTHGLNRTG YLICRYLIDV QGMRPDDAIE 180

LFNRCRGHCL ERQNYIEDLQ KGPIRRNWDS SISRSSGFED TTHMMEPVHT TIKSVNQGHW 240

YNLHQTQGYP VPSRHFHSQT QDLQQSVRKF SQNQNVYQRG HIPPPGPAGE DYSQRRYSWN 300

VKPNASQGAQ NAMWYPGSYY RLSYPTYCGW TE 332

Nucleotide Sequence
(FASTA)

ATGAGCCAGT GGCATCATGC CCGCGGCGGC TGGGGCCAGG GGCACGTGTT CTCTGGGCGT 60

CGCTCAGCCA AGAAGAAGCG CGGAAACCAC GTCCCGGAAA GGTGGAAAGA CTACCTCCCA 120

ATTGGACAAA GGATGCCTGG GACTCGTTTC ATTGCTTTCA AAGTTCCTTT GAAAAAGAGT 180

TTTGAAAAGA ATCTTGCTCC AGAAGAACGT TTTTCACCGT TGGATCTTTT TAACAAAATC 240

CAAAACCAGA ATGAAGAACT TGGACTGATT ATTGATTTAA CTTATACTCA CCGCTATTAT 300

AAACCAGAGG ACTTACCAGA AACTATTCCT CACTTAAAAA TTTATACAAT TGGGCATCAG 360

GTGCCTGATG ATGACACTAT TTTTAAATTC AAATGTGCTG TTAATGAGTT TTTAAAAGAA 420

AATACAGACA ATGACAAACT TATTGGTGTT CATTGTACCC ATGGTTTAAA CAGGACTGGC 480

TATCTCATCT GCAGATATTT GATTGATGTA CAAGGCATGA GGCCAGATGA TGCAATTGAA 540

TTATTCAATA GGTGCCGTGG ACATTGCTTA GAAAGACAAA ACTACATTGA AGACCTTCAG 600

AAAGGTCCCA TCAGAAGGAA TTGGGATTCC AGTATATCCA GATCAAGTGG TTTTGAAGAT 660

ACAACACATA TGATGGAACC AGTCCACACC ACTATTAAAT CTGTTAACCA AGGACATTGG 720

TATAACCTAC ATCAGACCCA AGGTTACCCA GTACCTTCTC GGCATTTCCA CAGCCAGACC 780

CAAGATTTGC AGCAGTCAGT AAGAAAATTT TCACAGAATC AGAATGTTTA CCAGAGAGGC 840

CATATCCCTC CTCCTGGTCC CGCTGGAGAG GACTATTCAC AAAGGAGGTA CTCTTGGAAC 900

GTAAAGCCAA ATGCCAGTCA AGGAGCCCAA AATGCAATGT GGTATCCTGG CAGTTATTAC 960

AGACTGTCCT ATCCAACCTA TTGTGGGTGG ACCGAATGA 999

Domain Profile

S: 26    lgitvvinaslsvikvqviPeylikkgityknipvdDsdvtdllqyfdeaaefideakek  85

         lg+ + ++ ++   k +  Pe + + +i   + +v D+d   ++++  +++ef++e++++

Q: 87    LGLIIDLTYTHRYYKPEDLPETIPHLKIYTIGHQVPDDD--TIFKFKCAVNEFLKENTDN  144

         466677788888888889999998888877777777776..59*****************

S: 86    ggkvlvHCaaGvsRSatlvlaYLmkveglslsdAieavkrkrpsiepnegfleQLl  141

         ++ + vHC++G++R+++l++ YL++v+g++ +dAie ++r+r+++ ++++++e L

Q: 145   DKLIGVHCTHGLNRTGYLICRYLIDVQGMRPDDAIELFNRCRGHCLERQNYIEDLQ  200

         *****************************************************986

Domain Sequence
(FASTA)

LGLIIDLTYT HRYYKPEDLP ETIPHLKIYT IGHQVPDDDT IFKFKCAVNE FLKENTDNDK 60

LIGVHCTHGL NRTGYLICRY LIDVQGMRPD DAIELFNRCR GHCLERQNYI EDLQ 114

Keyword

Complete proteome; Hydrolase; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Taeniopygia guttata"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0004725	; F:protein tyrosine phosphatase activity
GO:0008138	; F:protein tyrosine/serine/threonine phosphatase activity
GO:0035335	; P:peptidyl-tyrosine dephosphorylation

KEGG

InterPros

IPR000340	; Dual-sp_phosphatase_cat-dom.
IPR000387	; Tyr/Dual-specificity_Pase.
IPR016130	; Tyr_Pase_AS.

Pfam

PF00782

; DSPc; 1.

SMARTs

Prosites

PS00383	; TYR_PHOSPHATASE_1; 1.
PS50056	; TYR_PHOSPHATASE_2; 1.

Prints

Created Date

20-Feb-2013