EKS-CAF-00148

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CAF-00148

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Atypical/RIO	336.0	1.3E-100	182	398	217

Status

Unreviewed

Ensembl Protein

ENSCAFP00000014055

UniProt Accession

E2RP92;

Protein Name

Serine/threonine-protein kinase RIO1

Protein Synonyms/Alias

Gene Name

RIOK1

Gene Synonyms/Alias

RIOK1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCAFG00000009563	ENSCAFP00000014055	ENSCAFT00000015188

Organism

Canis familiaris

Functional Description

Protein Length

569

Protein Sequence
(FASTA)

MDYRRLLMSR VVPGQFDDAD SSDSESIDLK TVREQGDVQF ENLQKNVSEK AGGDEMEEEE 60

EEYDEEEDDD WDWDDGVGKL TKTYIFNARC NPQANRQTSN CNSAKMSTPA DKVLRKFENK 120

INLDKLNVTD SVINKVTEKS RQKEADMYRI KDKADRATVE QVLDPRTRMI LFKMLTRGII 180

SEINGCISTG KEANVYHAST ANGESRAIKI YKTSILVFKD RDKYVSGEFR FRHGYCKGNP 240

RKMVKTWAEK EMRNLIRLNT AQIPCPEPIL LRSHVLVMGF IGKDDMPAPL LKNVQLSESK 300

ARELYLQVIQ YMRRMYQDAR LVHADLSEFN MLYHSGDVYI IDVSQSVEHD HPHALEFLRK 360

DCANINDFFL KHSVAVMTVR ELFEFVTDPS ITHENMDAYL SKAMEIASQR TKEERSSQDH 420

VDEEVFKRAY IPRTLNEVKN YERDIDIMMK LKEEDMAMNA QQDNILYQTV TGLKKDLSGV 480

QKVPALLENQ DKEKTCSDSQ DAGSSECSDT DSEEQGDQAC SKKPTADVEV DKKERKKMVK 540

EAQREKRKSK IPKHVKKRKE KTARMKKGK 569

Nucleotide Sequence
(FASTA)

ATGGACTACC GCCGGCTGCT GATGAGTCGC GTGGTCCCGG GGCAGTTCGA CGACGCGGAC 60

TCCTCCGACA GTGAAAGTAT TGATTTGAAG ACCGTCAGAG AGCAAGGTGA TGTTCAGTTT 120

GAAAACCTGC AGAAGAATGT GTCTGAGAAG GCAGGTGGAG ATGAGATGGA GGAGGAAGAA 180

GAGGAGTATG ATGAGGAGGA GGACGACGAC TGGGACTGGG ATGATGGAGT TGGAAAACTC 240

ACCAAGACTT ATATCTTCAA TGCAAGGTGT AACCCCCAGG CAAATCGACA GACTTCCAAC 300

TGCAATTCAG CCAAAATGTC TACTCCAGCA GACAAGGTCT TACGGAAATT TGAGAATAAA 360

ATTAATCTAG ATAAGCTAAA TGTTACCGAT TCTGTCATAA ATAAAGTCAC CGAAAAGTCT 420

AGGCAAAAGG AAGCAGATAT GTATCGCATC AAAGATAAGG CAGACAGAGC AACGGTGGAA 480

CAGGTGTTGG ATCCTAGAAC ACGAATGATA TTATTCAAGA TGTTAACTAG AGGAATCATA 540

TCAGAAATAA ATGGCTGCAT TAGCACAGGA AAAGAAGCTA ATGTGTACCA TGCTAGCACA 600

GCAAATGGAG AGAGCAGAGC AATCAAAATT TACAAAACTT CTATTTTGGT GTTCAAAGAT 660

CGGGATAAGT ATGTAAGTGG GGAATTCAGA TTTCGTCATG GCTATTGTAA AGGAAACCCC 720

AGGAAAATGG TGAAAACTTG GGCAGAAAAA GAAATGAGGA ACTTAATCAG ACTAAACACA 780

GCACAGATCC CATGCCCAGA GCCTATCCTG CTGAGAAGTC ATGTTCTTGT CATGGGCTTC 840

ATTGGTAAAG ACGACATGCC AGCGCCACTG TTGAAAAACG TCCAGTTATC AGAATCCAAG 900

GCTCGGGAGT TGTATCTGCA GGTCATCCAG TACATGAGAA GAATGTATCA GGATGCCAGA 960

CTTGTCCATG CAGATCTCAG TGAATTTAAC ATGCTGTACC ATAGTGGAGA TGTGTACATC 1020

ATTGACGTTT CTCAGTCCGT AGAGCATGAC CACCCACATG CCTTGGAGTT CTTGAGAAAA 1080

GACTGTGCCA ATATCAATGA TTTCTTTTTG AAGCACAGTG TTGCTGTGAT GACTGTGCGG 1140

GAACTCTTTG AATTTGTCAC AGATCCATCC ATTACACATG AGAACATGGA CGCCTACCTC 1200

TCAAAGGCCA TGGAAATAGC ATCTCAGAGG ACCAAGGAAG AAAGGTCCAG CCAAGATCAT 1260

GTGGACGAGG AGGTGTTTAA GCGAGCATAT ATTCCTAGAA CCTTGAATGA AGTAAAAAAT 1320

TATGAACGGG ATATAGATAT AATGATGAAA TTGAAGGAAG AGGACATGGC CATGAATGCC 1380

CAGCAAGACA ATATTCTGTA CCAAACCGTT ACAGGATTGA AGAAAGATTT GTCAGGAGTT 1440

CAGAAGGTTC CTGCACTTCT AGAAAATCAA GATAAGGAAA AGACTTGTTC TGATTCACAA 1500

GACGCTGGAA GCTCTGAGTG TTCTGACACA GACTCTGAAG AGCAGGGAGA CCAGGCCTGC 1560

TCTAAGAAAC CCACTGCTGA CGTTGAAGTT GATAAAAAGG AAAGAAAAAA GATGGTCAAA 1620

GAAGCCCAGA GAGAGAAAAG AAAAAGCAAA ATTCCGAAGC ATGTGAAAAA AAGAAAGGAG 1680

AAGACAGCCA GGATGAAAAA GGGCAAATAG 1710

Domain Profile

S: 2     svgntigvgkesdvykvsekngeeraiKiyktsllvlknrdkYvdgefrfkksrskanpr  61

         +++++i++gke++vy++s++nge+raiKiykts+lv+k+rdkYv+gefrf+++++k npr

Q: 182   EINGCISTGKEANVYHASTANGESRAIKIYKTSILVFKDRDKYVSGEFRFRHGYCKGNPR  241

         699*********************************************************

S: 62    klsrlwAeKEfrnlkrlyekgvpvPepidlkrhvlvmeligrdgypapklkdvklkeeei  121

         k++++wAeKE+rnl+rl+++++p+Pepi l++hvlvm +ig+d++pap lk+v+l+e+++

Q: 242   KMVKTWAEKEMRNLIRLNTAQIPCPEPILLRSHVLVMGFIGKDDMPAPLLKNVQLSESKA  301

         ************************************************************

S: 122   kelYsdllalivklynegrLvHaDlsEfnilleddklvliDvsqsveieHpdaleflrrD  181

         +elY +++++++++y+++rLvHaDlsEfn+l++++++++iDvsqsve++Hp+aleflr+D

Q: 302   RELYLQVIQYMRRMYQDARLVHADLSEFNMLYHSGDVYIIDVSQSVEHDHPHALEFLRKD  361

         ************************************************************

S: 182   vknvkefFkkklvydvlrerelfelvsasgltkekead  219

         ++n+++fF k++v +v+++relfe+v++ ++t+e+++

Q: 362   CANINDFFLKHSV-AVMTVRELFEFVTDPSITHENMDA  398

         *************.*********************985

Domain Sequence
(FASTA)

EINGCISTGK EANVYHASTA NGESRAIKIY KTSILVFKDR DKYVSGEFRF RHGYCKGNPR 60

KMVKTWAEKE MRNLIRLNTA QIPCPEPILL RSHVLVMGFI GKDDMPAPLL KNVQLSESKA 120

RELYLQVIQY MRRMYQDARL VHADLSEFNM LYHSGDVYII DVSQSVEHDH PHALEFLRKD 180

CANINDFFLK HSVAVMTVRE LFEFVTDPSI THENMDA 217

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>