EKS-CAF-00015

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CAF-00015

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/PHK	515.2	4.6E-155	163	431	269

Status

Unreviewed

Ensembl Protein

ENSCAFP00000014940

UniProt Accession

E2RKP3;

Protein Name

Protein Synonyms/Alias

Gene Name

PHKG1

Gene Synonyms/Alias

PHKG1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCAFG00000010171	ENSCAFP00000014940	ENSCAFT00000016154

Organism

Canis familiaris

Functional Description

Protein Length

530

Protein Sequence
(FASTA)

MAPRKVNAFP PWLALSPLGL ETKGAPEGRL VTSCCPVGSQ ATEFPSPSSR GHLLVRLGPH 60

EPWPASQVCS CGLFLVRQAS VTKKQSLKDE QQNILLWPQV SAGDLLQPSA CPLSSRGSEA 120

FGIPATFTQG PVRIKQVAPK LWSMTRDEAL PDSYSAQGFY ENYEPKEILG RGVSSVVRRC 180

IHKPTCQEYA VKIIDITGGG SFSSAEVQEL REATLKEVDI LRKVSGLPNI IQLKDTYETN 240

TFFFLVFDLM KRGELFDYLT EKVTLSEKET RKIMRALLEV IRNLHKLNIV HRDLKPENIL 300

LDDDMNIKLT DFGFSCQLEP GEKLREVCGT PSYLAPEIIE CSMNDDHPGY GKEVDMWSIG 360

VIMYTLLAGS PPFWHRKQML MLRMIMSGNY QFGSPEWDDY SDTVKDLVSR FLVVNPQGRC 420

SAEEALAHPF FQQYVVEEVR HFSPRGKFKV IALTVLASVR IYYQYRRVKP VTREIVIRDP 480

YALRPLRRLI DAYAFRIYGH WVKKGQQQNR AALFENTPKA VLLSLAEEDY 530

Nucleotide Sequence
(FASTA)

ATGGCTCCCA GAAAAGTGAA TGCATTTCCA CCATGGCTAG CTTTGTCTCC TCTAGGCCTG 60

GAGACCAAGG GAGCTCCAGA GGGAAGACTG GTCACCTCTT GCTGTCCTGT GGGCTCCCAG 120

GCCACCGAGT TTCCCTCACC CTCCAGCAGA GGTCACCTCC TGGTGAGACT TGGCCCCCAT 180

GAGCCTTGGC CTGCATCCCA GGTCTGCAGT TGTGGTTTAT TTCTGGTACG TCAGGCTTCC 240

GTCACCAAGA AGCAGAGCCT GAAGGACGAG CAGCAAAATA TCCTGCTGTG GCCACAAGTG 300

TCTGCTGGGG ACCTGCTTCA GCCCTCGGCC TGTCCCCTCT CATCAAGGGG CTCTGAGGCC 360

TTTGGGATTC CTGCCACATT CACTCAAGGG CCTGTGAGGA TCAAACAAGT TGCCCCCAAG 420

TTGTGGAGCA TGACTCGGGA CGAGGCACTG CCAGACTCGT ACTCAGCACA GGGCTTCTAT 480

GAAAACTATG AGCCCAAGGA GATCCTGGGC AGAGGAGTTA GCAGCGTCGT CAGGCGCTGC 540

ATCCACAAGC CCACGTGCCA GGAGTATGCT GTGAAGATCA TTGACATCAC TGGCGGAGGC 600

AGCTTCAGCT CTGCGGAGGT CCAGGAGCTG CGAGAGGCCA CACTGAAGGA GGTGGACATC 660

CTGCGCAAGG TCTCTGGGCT CCCCAACATC ATACAGCTGA AGGACACTTA TGAGACCAAC 720

ACTTTCTTCT TCCTGGTGTT TGATCTGATG AAGAGAGGGG AGCTCTTTGA TTATCTCACT 780

GAGAAGGTCA CTCTGAGTGA GAAGGAAACC AGAAAGATCA TGAGAGCCCT GCTGGAGGTT 840

ATCCGCAACT TGCACAAACT CAACATTGTA CATCGGGATC TGAAGCCTGA GAATATCCTC 900

TTGGATGATG ACATGAACAT TAAGCTCACA GACTTTGGTT TTTCCTGCCA GCTGGAGCCA 960

GGAGAGAAGC TGCGAGAGGT CTGTGGGACT CCCAGCTACC TGGCCCCTGA GATCATTGAG 1020

TGCTCCATGA ATGATGACCA CCCAGGCTAT GGGAAGGAGG TGGACATGTG GAGCATAGGG 1080

GTCATCATGT ACACCCTGCT GGCCGGCTCC CCACCCTTTT GGCACCGGAA ACAGATGCTG 1140

ATGCTGAGGA TGATCATGAG TGGCAACTAC CAGTTTGGCT CACCTGAATG GGATGACTAT 1200

TCAGACACTG TGAAGGATTT GGTTTCCCGT TTCTTGGTGG TGAACCCCCA GGGCCGCTGT 1260

TCTGCAGAAG AGGCCTTAGC GCATCCCTTC TTCCAGCAGT ATGTGGTGGA GGAAGTGCGT 1320

CACTTTAGCC CCCGGGGCAA GTTCAAGGTG ATTGCTCTAA CAGTACTGGC TTCGGTGCGG 1380

ATCTATTACC AGTACCGCCG GGTGAAGCCT GTGACCCGGG AGATTGTCAT CCGTGACCCC 1440

TATGCCCTCC GGCCTCTGCG CCGACTCATT GATGCCTACG CTTTCCGAAT CTATGGCCAC 1500

TGGGTGAAGA AGGGACAACA GCAAAACCGG GCTGCCCTTT TTGAGAACAC ACCCAAGGCT 1560

GTGCTCCTCT CCCTGGCTGA GGAAGATTAC TAA 1593

Domain Profile

S: 1     yepkeilGrGvssvvrrciekatgqefavkiidvs.aeklseeevkelreatlkeveilr  59

         yepkeilGrGvssvvrrci+k+t+qe+avkiid++ ++++s+ ev+elreatlkev+ilr

Q: 163   YEPKEILGRGVSSVVRRCIHKPTCQEYAVKIIDITgGGSFSSAEVQELREATLKEVDILR  222

         9**********************************899**********************

S: 60    qvsGhpsiiklkdvyesssflflvfdlmkkGelfdyltekvtlseketrkimralleave  119

         +vsG p+ii+lkd+ye+++f+flvfdlmk+Gelfdyltekvtlseketrkimralle++

Q: 223   KVSGLPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLSEKETRKIMRALLEVIR  282

         ************************************************************

S: 120   ylhaknivhrdlkpenillddneniklsdfGfstqleeGeklrelcGtpgylapeilkcs  179

          lh+ nivhrdlkpenilldd++nikl+dfGfs+qle+Geklre+cGtp+ylapei++cs

Q: 283   NLHKLNIVHRDLKPENILLDDDMNIKLTDFGFSCQLEPGEKLREVCGTPSYLAPEIIECS  342

         ************************************************************

S: 180   mdeeapGyskevdlwalGvilytllaGsppfwhrkqllmlrlimeGkyqftspewddise  239

         m++++pGy+kevd+w++Gvi+ytllaGsppfwhrkq+lmlr+im+G+yqf+spewdd+s+

Q: 343   MNDDHPGYGKEVDMWSIGVIMYTLLAGSPPFWHRKQMLMLRMIMSGNYQFGSPEWDDYSD  402

         ************************************************************

S: 240   evkdliskllvvdpekrltaeealahpff  268

         +vkdl+s++lvv+p+ r++aeealahpff

Q: 403   TVKDLVSRFLVVNPQGRCSAEEALAHPFF  431

         ****************************8

Domain Sequence
(FASTA)

YEPKEILGRG VSSVVRRCIH KPTCQEYAVK IIDITGGGSF SSAEVQELRE ATLKEVDILR 60

KVSGLPNIIQ LKDTYETNTF FFLVFDLMKR GELFDYLTEK VTLSEKETRK IMRALLEVIR 120

NLHKLNIVHR DLKPENILLD DDMNIKLTDF GFSCQLEPGE KLREVCGTPS YLAPEIIECS 180

MNDDHPGYGK EVDMWSIGVI MYTLLAGSPP FWHRKQMLML RMIMSGNYQF GSPEWDDYSD 240

TVKDLVSRFL VVNPQGRCSA EEALAHPFF 269

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005964	; C:phosphorylase kinase complex
GO:0005524	; F:ATP binding
GO:0004689	; F:phosphorylase kinase activity
GO:0005978	; P:glycogen biosynthetic process

KEGG

InterPros

IPR020636	; Ca/CaM-dep_Ca-dep_prot_Kinase.
IPR011009	; Kinase-like_dom.
IPR002291	; Phosph_kin_gamma.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

PR01049

; PHOSPHBKNASE.

Created Date

20-Feb-2013