EKS-CAF-00337

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CAF-00337

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
STE/STE20	315.7	2.8E-94	66	336	271

Status

Unreviewed

Ensembl Protein

ENSCAFP00000017370

UniProt Accession

F1P6R3;

Protein Name

Protein Synonyms/Alias

Gene Name

STK39

Gene Synonyms/Alias

STK39;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCAFG00000011768	ENSCAFP00000017338	ENSCAFT00000018716
ENSCAFG00000011768	ENSCAFP00000017370	ENSCAFT00000018748

Organism

Canis familiaris

Functional Description

Protein Length

543

Protein Sequence
(FASTA)

SRPRGAPPPP APPPPPPPPP AAAAAARTCP ERRRLPPRDL RDSASRAPAG AAAEAGAGRE 60

ASVPQQVIGS GATAVVQAAL CKPRQERVAI KRINLEKCQT SMDELLKEIQ AMSQCSHPNV 120

VTYYTSFVVK DELWLVMKLL SGGSMLDIIK YIVNRGEHKN GVLEEAIIAT ILKEVLEGLD 180

YLHRNGQIHR DLKAGNILLG EDGSVQIADF GVSAFLATGG DVTRNKVRKT FVGTPCWMAP 240

EVMEQVRGYD FKADMWSFGI TAIELATGAA PYHKYPPMKV LMLTLQNDPP TLETGVEDKE 300

MMKKYGKSFR KLLSLCLQKD PSKRPTAAEL LKCKFFQKAK NREYLIEKLL TRTPDIAQRA 360

KKVRRVPGSS GHLHKTEDGD WEWSDDEMDE KSEEGKAAFS QEKSRRVKEE NPEMAVNASS 420

IPEQIQSLSV QDSQGLPNAS EDYRETSCAV NLVLRLRNSR KELNDIRFEF TPGRDTADGV 480

SQELFSAGLV DGHDVVIVAA NLQKIVDDPK ALKTLTFKLA SGCDGSEIPD EVKLIGFAQL 540

SVS 543

Nucleotide Sequence
(FASTA)

TCCCGCCCCC GGGGGGCCCC CCCCCCCCCC GCCCCCCCCC CCCCCCCGCC CCCCCCCCCA 60

GCAGCCGCCG CCGCCGCCCG CACATGCCCA GAACGCCGCC GCCTGCCCCC GCGGGACCTT 120

CGGGACTCGG CTTCCCGCGC GCCCGCAGGC GCTGCTGCGG AGGCAGGTGC GGGCAGGGAA 180

GCATCTGTGC CACAGCAAGT CATAGGCAGC GGAGCTACCG CCGTGGTGCA GGCTGCCCTG 240

TGCAAGCCCC GGCAGGAGCG CGTGGCAATT AAGCGGATCA ACCTGGAGAA ATGCCAGACC 300

AGCATGGATG AGCTCCTGAA AGAAATTCAA GCCATGAGTC AGTGCAGCCA TCCCAATGTA 360

GTGACCTATT ACACCTCTTT TGTGGTAAAA GATGAACTTT GGCTGGTCAT GAAATTACTA 420

AGTGGAGGTT CCATGTTGGA TATCATAAAA TACATTGTCA ACCGAGGGGA ACACAAGAAT 480

GGAGTTCTGG AGGAGGCAAT AATAGCAACA ATTCTTAAAG AGGTTTTGGA AGGCTTAGAC 540

TATCTACACA GAAACGGTCA GATTCACAGG GACTTGAAAG CTGGTAATAT TCTTCTGGGT 600

GAGGATGGTT CGGTACAAAT AGCAGATTTT GGGGTAAGTG CATTCTTAGC AACAGGGGGT 660

GATGTTACCC GGAATAAAGT AAGAAAAACA TTTGTTGGTA CTCCGTGTTG GATGGCCCCT 720

GAAGTCATGG AACAGGTGAG AGGCTATGAC TTCAAGGCTG ACATGTGGAG TTTTGGAATA 780

ACTGCCATTG AATTAGCAAC AGGAGCAGCG CCTTATCACA AATATCCTCC TATGAAAGTG 840

TTAATGTTGA CTTTGCAAAA TGATCCACCC ACTTTAGAAA CAGGAGTGGA GGATAAGGAA 900

ATGATGAAAA AGTACGGCAA GTCCTTTAGG AAATTACTTT CACTGTGTCT TCAGAAAGAT 960

CCTTCTAAAA GGCCCACAGC CGCAGAACTT TTAAAATGCA AATTCTTCCA GAAAGCCAAG 1020

AACAGAGAGT ACCTGATTGA GAAGCTGCTT ACAAGAACCC CAGACATAGC CCAAAGAGCC 1080

AAAAAGGTGA GAAGAGTTCC TGGGTCGAGT GGTCACCTTC ATAAAACCGA GGACGGTGAC 1140

TGGGAGTGGA GTGACGACGA GATGGATGAG AAAAGTGAAG AAGGGAAGGC AGCCTTTTCT 1200

CAAGAAAAGT CACGAAGAGT AAAAGAAGAA AATCCAGAGA TGGCGGTGAA TGCCAGCAGT 1260

ATACCCGAGC AAATACAGTC CCTCTCTGTG CAGGACTCTC AGGGCCTACC CAATGCTAGT 1320

GAAGACTATA GAGAAACTTC TTGTGCTGTG AACCTCGTTT TAAGATTAAG AAACTCCAGA 1380

AAGGAACTTA ATGACATACG GTTTGAGTTT ACTCCAGGAA GAGATACGGC AGATGGTGTA 1440

TCTCAGGAGC TCTTCTCTGC TGGCTTGGTT GATGGTCATG ATGTAGTTAT AGTGGCTGCT 1500

AATTTACAGA AGATTGTAGA TGATCCCAAA GCTTTAAAAA CATTGACGTT TAAGTTGGCT 1560

TCAGGCTGTG ATGGGTCGGA GATTCCTGAT GAAGTGAAGC TGATCGGGTT TGCTCAGTTG 1620

AGTGTCAGC 1629

Domain Profile

S: 5     eeigkGalgkvylarekktgelvaikkinlekq.ekleelqkeisvlkklkhpniveyle  63

         ++ig+Ga++ v++a +k+++e vaik+inlek+ ++++el kei+++++++hpn+v+y++

Q: 66    QVIGSGATAVVQAALCKPRQERVAIKRINLEKCqTSMDELLKEIQAMSQCSHPNVVTYYT  125

         78*******************************8899***********************

S: 64    sflkeeelwlvmeylagGslsdlvk......eelkselkEeqiayilrevlkaLeylHsk  117

         sf++++elwlvm++l+gGs+ d++k      e+++  l+E  ia+il+evl++L+ylH++

Q: 126   SFVVKDELWLVMKLLSGGSMLDIIKyivnrgEHKNGVLEEAIIATILKEVLEGLDYLHRN  185

         ******************************999***************************

S: 118   kviHrdikakniLlteegeVkLsdfgvaaqlek....trkk.rktvvgtpywmAPEviaq  172

         ++iHrd+ka+niLl e+g+V+++dfgv+a l++    tr+k rkt+vgtp+wmAPEv++q

Q: 186   GQIHRDLKAGNILLGEDGSVQIADFGVSAFLATggdvTRNKvRKTFVGTPCWMAPEVMEQ  245

         *******************************99888888899*****************5

S: 173   eekgYdekaDiwslGItaielaegepPfkdleplkallkilkneppklksk.......kk  225

           +gYd kaD+ws+GItaiela+g++P+++++p+k+l+++l+n+pp+l++        kk

Q: 246   -VRGYDFKADMWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPTLETGvedkemmKK  304

         .9**********************************************666667777799

S: 226   fskefkefvekclqknpekRpsasellkhkFl  257

         ++k+f+++++ clqk+p+kRp+a+ellk kF+

Q: 305   YGKSFRKLLSLCLQKDPSKRPTAAELLKCKFF  336

         ******************************97

Domain Sequence
(FASTA)

QVIGSGATAV VQAALCKPRQ ERVAIKRINL EKCQTSMDEL LKEIQAMSQC SHPNVVTYYT 60

SFVVKDELWL VMKLLSGGSM LDIIKYIVNR GEHKNGVLEE AIIATILKEV LEGLDYLHRN 120

GQIHRDLKAG NILLGEDGSV QIADFGVSAF LATGGDVTRN KVRKTFVGTP CWMAPEVMEQ 180

VRGYDFKADM WSFGITAIEL ATGAAPYHKY PPMKVLMLTL QNDPPTLETG VEDKEMMKKY 240

GKSFRKLLSL CLQKDPSKRP TAAELLKCKF F 271

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Cavia porcellus"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Rattus norvegicus"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004672	; F:protein kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR024678	; Kinase_OSR1/WNK_CCT.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.

Pfam

PF12202	; OSR1_C; 1.
PF00069	; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.

Prints

Created Date

20-Feb-2013