EKS-CAF-00167

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CAF-00167

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/RSKb	496.7	1.6E-149	427	684	258

Status

Unreviewed

Ensembl Protein

ENSCAFP00000018358

UniProt Accession

F1PIL4;

Protein Name

Protein Synonyms/Alias

Gene Name

Cfa.42781

Gene Synonyms/Alias

Cfa.42781;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCAFG00000012408	ENSCAFP00000018364	ENSCAFT00000019797
ENSCAFG00000012408	ENSCAFP00000018358	ENSCAFT00000019791

Organism

Canis familiaris

Functional Description

Protein Length

744

Protein Sequence
(FASTA)

MEQDPKPPRL RLWALLPWLP RKQRPRTSQT SLPAPGPGSG PRRDLDEGVL KEISITHHVK 60

AGSEKADPSH FELLKVLGQG SFGKVFLVRK ITRPDSGHLY AMKVLKKATL KVRDRVRTKM 120

ERDILADVNH PFVVKLHYAF QTEGKLYLIL DFLRGGDLFT RLSKEVMFTE EDVKFYLAEL 180

ALGLDHLHSL GIIYRDLKPE NILLDEEGHI KLTDFGLSKE AIDHEKKAYS FCGTVEYMAP 240

EVVNRQGHTH SADWWSYGVL MFEMLTGSLP FQGKDRKETM TLILKAKLGM PQFLSTEAQS 300

LLRALFKRNP ANRLGSGPDG AEEIKRHAFY STIDWNKLYR REIKPPFKPA VAQPDDTFYF 360

DTEFTSRTPK DSPGIPPSAG AHQLFRGFSF VATGLMEDDG KPRAPQAPLH SVVQQLHGKN 420

LVFSDGYVVK ETIGVGSYSV CKRCVHKATN MEYAVKVIDK SKRDPSEEIE ILLRYGQHPN 480

IITLKDVYDD GKHVYLVTEL MRGGELLDKI LRQKFFSERE ASFVLHTISK TVEYLHSQGV 540

VHRDLKPSNI LYVDESGNPE CLRICDFGFA KQLRAENGLL MTPCYTANFV APEVLKRQGY 600

DEGCDIWSLG ILLYTMLAGY TPFANGPSDT PEEILTRIGS GKFTLSGGNW STVSETAKDL 660

VSKMLHVDPH QRLTAKQVLQ HPWITQKDKL PQSQLSHQDL QLVKGAMAAT YSALNSSKPT 720

PQLKPIESSI LAQRRVRKLP STTL 744

Nucleotide Sequence
(FASTA)

ATGGAGCAGG ATCCCAAGCC GCCCCGCCTG CGGCTCTGGG CCCTGCTCCC CTGGCTGCCC 60

AGGAAGCAGC GGCCCAGGAC CAGCCAGACC TCTTTGCCTG CCCCTGGCCC TGGCTCTGGC 120

CCCAGGCGGG ACTTGGATGA GGGCGTCCTA AAGGAGATCT CCATCACGCA CCATGTCAAG 180

GCTGGCTCTG AGAAGGCCGA CCCATCCCAT TTTGAGCTGC TCAAGGTTCT GGGCCAGGGA 240

TCCTTTGGCA AAGTCTTCCT AGTGCGGAAA ATCACCCGAC CTGATAGTGG GCACCTGTAT 300

GCCATGAAGG TACTAAAGAA GGCAACGCTG AAAGTGCGTG ACCGCGTTCG GACCAAGATG 360

GAGAGAGACA TCCTAGCAGA TGTGAACCAC CCATTTGTGG TGAAGCTGCA CTATGCCTTC 420

CAGACGGAGG GAAAGCTCTA TCTTATCCTG GACTTCCTGC GTGGTGGAGA CCTCTTTACC 480

CGGCTCTCTA AAGAGGTTAT GTTCACAGAG GAGGATGTGA AGTTTTACCT GGCTGAGCTG 540

GCTTTGGGCC TGGACCACCT GCACAGCTTG GGCATCATTT ATAGAGACCT CAAGCCTGAA 600

AACATCCTTC TGGATGAGGA GGGCCACATA AAACTCACTG ACTTTGGCCT GAGCAAGGAG 660

GCCATCGACC ATGAGAAAAA AGCCTATTCC TTCTGTGGGA CGGTGGAGTA CATGGCCCCC 720

GAGGTCGTCA ACCGCCAGGG CCACACCCAC AGTGCAGACT GGTGGTCCTA TGGGGTGTTG 780

ATGTTTGAGA TGCTGACAGG CTCCCTGCCC TTCCAGGGAA AGGACCGGAA GGAGACCATG 840

ACACTGATTC TGAAGGCGAA GCTAGGCATG CCCCAGTTTC TGAGCACAGA AGCCCAGAGC 900

CTCCTGCGGG CCCTGTTCAA GCGGAATCCT GCCAACCGGC TTGGCTCCGG CCCTGATGGG 960

GCAGAAGAAA TCAAGAGGCA TGCCTTCTAC TCTACCATTG ATTGGAATAA GCTATACCGT 1020

CGTGAGATCA AGCCACCCTT CAAGCCGGCT GTGGCACAAC CTGATGACAC CTTCTACTTT 1080

GACACTGAGT TCACCTCCCG CACACCCAAG GACTCCCCAG GCATCCCCCC CAGTGCTGGT 1140

GCCCATCAGC TGTTCCGTGG CTTCAGCTTC GTGGCCACTG GCCTGATGGA GGATGACGGC 1200

AAGCCTCGGG CCCCACAGGC ACCACTGCAC TCAGTGGTAC AGCAACTCCA CGGGAAAAAC 1260

CTGGTTTTTA GCGATGGCTA CGTTGTAAAG GAGACGATTG GTGTGGGCTC CTACTCCGTG 1320

TGCAAGCGCT GTGTACATAA GGCCACTAAT ATGGAGTATG CTGTCAAGGT CATCGACAAG 1380

AGCAAGCGGG ATCCCTCAGA AGAGATTGAG ATTCTTCTGC GGTATGGGCA GCACCCCAAC 1440

ATCATCACTC TGAAAGACGT GTACGATGAT GGCAAACACG TGTATCTGGT GACAGAGCTG 1500

ATGCGGGGTG GGGAGCTGCT AGACAAGATC TTGCGGCAGA AATTCTTCTC CGAGCGGGAG 1560

GCCAGCTTTG TCCTGCACAC CATCAGCAAA ACCGTGGAGT ATCTGCACTC CCAGGGGGTT 1620

GTTCATAGGG ACCTCAAGCC CAGCAATATC CTGTACGTGG ACGAGTCTGG GAACCCTGAG 1680

TGCCTACGCA TCTGTGATTT TGGCTTTGCC AAGCAGCTAC GGGCAGAGAA TGGGCTCCTC 1740

ATGACACCTT GCTACACTGC CAACTTTGTG GCACCTGAGG TGCTGAAACG CCAGGGCTAT 1800

GATGAAGGCT GTGACATCTG GAGCCTGGGC ATTCTGCTGT ACACCATGCT GGCGGGATAC 1860

ACTCCATTTG CCAACGGACC CAGTGACACA CCAGAGGAAA TCCTGACCCG GATCGGCAGT 1920

GGGAAGTTCA CCCTGAGTGG GGGAAATTGG AGCACAGTTT CAGAGACAGC CAAGGACCTG 1980

GTGTCCAAGA TGCTGCATGT GGACCCCCAC CAGCGCCTCA CAGCTAAGCA GGTCCTGCAG 2040

CACCCATGGA TCACCCAAAA AGACAAGCTC CCTCAGAGCC AGCTGTCCCA CCAAGACCTG 2100

CAACTTGTGA AGGGAGCCAT GGCGGCTACA TACTCTGCAC TCAACAGCTC CAAGCCCACC 2160

CCTCAGCTGA AGCCCATCGA GTCATCTATC CTAGCCCAGC GGCGGGTGAG GAAGCTGCCT 2220

TCCACCACCC TG 2232

Domain Profile

S: 1     yevkedlGvGsysvckrcvhkatnqefavkiidkskrdtseeieillryeqhpnivtlkd  60

         y+vke++GvGsysvckrcvhkatn+e+avk+idkskrd+seeieillry+qhpni+tlkd

Q: 427   YVVKETIGVGSYSVCKRCVHKATNMEYAVKVIDKSKRDPSEEIEILLRYGQHPNIITLKD  486

         689*********************************************************

S: 61    vyddgkyvylvlellkGGelldrikkkkffsereasailrtlvkaveylheqGvvhrdlk  120

         vyddgk+vylv+el++GGelld+i+++kffsereas +l+t++k+veylh+qGvvhrdlk

Q: 487   VYDDGKHVYLVTELMRGGELLDKILRQKFFSEREASFVLHTISKTVEYLHSQGVVHRDLK  546

         ************************************************************

S: 121   penilyvdesdnaesikiidfGfaklkraengllktpcytlnfvapevlkrqGydeacdl  180

         p+nilyvdes+n+e+++i+dfGfak++raengll+tpcyt+nfvapevlkrqGyde+cd+

Q: 547   PSNILYVDESGNPECLRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDEGCDI  606

         ************************************************************

S: 181   wslGvllytmlaGyvpfangpedtaeeilakikeGkfslsGeawdsvseeakdlvskllt  240

         wslG+llytmlaGy+pfangp+dt+eeil++i++Gkf+lsG++w++vse+akdlvsk+l+

Q: 607   WSLGILLYTMLAGYTPFANGPSDTPEEILTRIGSGKFTLSGGNWSTVSETAKDLVSKMLH  666

         ************************************************************

S: 241   vdpakrlkleqllkhswl  258

         vdp++rl+++q+l+h+w+

Q: 667   VDPHQRLTAKQVLQHPWI  684

         *****************8

Domain Sequence
(FASTA)

YVVKETIGVG SYSVCKRCVH KATNMEYAVK VIDKSKRDPS EEIEILLRYG QHPNIITLKD 60

VYDDGKHVYL VTELMRGGEL LDKILRQKFF SEREASFVLH TISKTVEYLH SQGVVHRDLK 120

PSNILYVDES GNPECLRICD FGFAKQLRAE NGLLMTPCYT ANFVAPEVLK RQGYDEGCDI 180

WSLGILLYTM LAGYTPFANG PSDTPEEILT RIGSGKFTLS GGNWSTVSET AKDLVSKMLH 240

VDPHQRLTAK QVLQHPWI 258

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR000961	; AGC-kinase_C.
IPR011009	; Kinase-like_dom.
IPR017892	; Pkinase_C.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069	; Pkinase; 2.
PF00433	; Pkinase_C; 1.

SMARTs

SM00133	; S_TK_X; 1.
SM00220	; S_TKc; 2.

Prosites

PS51285	; AGC_KINASE_CTER; 1.
PS00107	; PROTEIN_KINASE_ATP; 2.
PS50011	; PROTEIN_KINASE_DOM; 2.
PS00108	; PROTEIN_KINASE_ST; 2.

Prints

Created Date

20-Feb-2013