EKS-CAF-00486

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CAF-00486

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/RSKL	305.9	5.9E-91	884	1056	173

Status

Unreviewed

Ensembl Protein

ENSCAFP00000018304

UniProt Accession

E2RR13;

Protein Name

Protein Synonyms/Alias

Gene Name

RPS6KC1

Gene Synonyms/Alias

RPS6KC1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCAFG00000012413	ENSCAFP00000018304	ENSCAFT00000019734

Organism

Canis familiaris

Functional Description

Protein Length

1066

Protein Sequence
(FASTA)

MTSPRERGGD LARFYTVTEP QRHPRGYTVY KVTARVVSRR NPEDVQEIIV WKRYSDFKKL 60

HKELWQIHKN LFRHSELFPP FAKGIVFGRF DETVIEERRQ CAEDLLQFSA NIPALYNSKQ 120

LEDFFKGGII NDGSELIGPA EAYSDSLVDS FPECSTEGFS SDSDLISLTV DVDSLAELDD 180

GMASNQNSPV RTFGLNLSSD PSALGAVASD SEQNKPEEER ESRSLFPGSL KSKLGKRDYL 240

EKAGELIKLA LKKEEEDDYE AASNFYRKGV DLLLEGVQGE SSPTRREAVK RKTAEYLMRA 300

ENLSSLYGKP QLDDVSQPPG SRSSKPPWNL RSPAEELKAF RVLGVIDKVL LVMDTRTEQT 360

FILKGLRKSS EYSRNRKTII PRCVPNMVCL HKYIVSEESV FLVLQHAEGG KLWSYISKFL 420

NRSPEESFDI GEVKKSTLTK VHLQQPTSSP QDSSSFESRG SDGGTIHKVL PLKTSLTPSS 480

QDDSNQDEEG QDSSPKWPDS GSSSEEECTT SYLTLCNEYG QEKIEPGSLN EESFMKIGGN 540

GVDTKVIESF PTHLAADSDS PSTQQMAHEL KFFAGDDAVE AISSPGTSDS LNRSKNSPME 600

FFRIDSKDST SELLGLDFGE KLYSLKSEPL KPFFTLPDGD STSRSFTTSE SKIEFIAQDT 660

ISRGSDDSVP VISFKDAAFD DVIGTDEGRP DLLVNLPGEL EATKDGAAVG PTKFTQTNIG 720

IIESKLLEAP DVLCLRLSTE QCQASEEEGT EELSDPSRPK SHSIAEKHNA QGDLGMLFVA 780

AVDHSSSGDM SLSHSSDPNF QGLGVVESAV TANNTEESLF RISNPLSGAN EYNVNTDTLK 840

TEEVLLFTDQ TEDLAKEELT LFQRDSATKG ESGLALEGDK EIHQLFEDLD KKLALNSRFY 900

IPEGCIQRWA AEMVVALDAL HREGIVCRDL NPNNILLNDR GHIQLTYFSR WSEVEDSCDS 960

DAIERMYCAP EVGAITEETE ACDWWSLGAV LFELLTGKTL VECHPAGINT HTTLNMPECV 1020

SEEARSLIQQ LLQFNPVERL GAGVAGVEDI KSHPFFNPVD WAELMR 1066

Nucleotide Sequence
(FASTA)

ATGACCTCTC CCCGGGAGCG GGGTGGCGAC CTGGCCCGTT TCTACACTGT CACCGAGCCC 60

CAGCGACATC CCAGGGGCTA CACGGTGTAT AAGGTCACCG CCCGGGTTGT TTCACGAAGA 120

AATCCAGAGG ATGTCCAGGA GATAATCGTA TGGAAGAGAT ACAGTGACTT TAAGAAACTA 180

CACAAAGAAC TATGGCAAAT TCACAAAAAC TTATTCCGAC ATTCAGAATT GTTTCCTCCA 240

TTTGCTAAAG GAATAGTGTT TGGACGATTT GATGAAACTG TCATTGAAGA GAGAAGACAG 300

TGTGCTGAAG ATTTGCTACA GTTCTCTGCC AATATCCCTG CTCTTTATAA CAGTAAACAA 360

CTTGAAGATT TTTTCAAGGG TGGAATAATT AATGATGGTT CTGAATTGAT TGGTCCTGCT 420

GAAGCTTATT CTGATTCCCT CGTTGATAGC TTTCCTGAGT GTAGTACAGA AGGTTTCTCC 480

AGTGACAGTG ATCTGATATC TCTTACTGTT GACGTGGATT CTCTTGCTGA GTTAGATGAT 540

GGAATGGCTT CCAATCAAAA TTCTCCCGTT AGAACTTTTG GTCTCAATCT TTCTTCGGAT 600

CCTTCAGCAC TAGGGGCTGT TGCTTCTGAC AGTGAACAGA ACAAACCAGA AGAAGAACGA 660

GAAAGTCGCA GCCTCTTCCC TGGCAGTTTA AAATCTAAGC TTGGCAAGAG AGATTATTTG 720

GAGAAAGCCG GAGAATTAAT AAAGCTGGCT TTAAAAAAAG AAGAAGAAGA TGACTATGAA 780

GCTGCTTCCA ATTTTTATAG GAAAGGAGTT GATTTACTCC TAGAAGGTGT TCAAGGAGAG 840

TCAAGCCCTA CACGTCGAGA AGCTGTGAAG AGAAAAACAG CAGAGTATCT CATGCGAGCA 900

GAGAATCTAT CCAGCCTTTA TGGAAAACCT CAACTTGATG ATGTATCCCA GCCTCCAGGA 960

TCACGAAGTT CAAAGCCCCC TTGGAACCTA AGGAGTCCTG CCGAGGAGCT GAAGGCCTTT 1020

AGAGTCCTTG GGGTGATTGA CAAGGTTTTA CTTGTAATGG ATACAAGGAC AGAACAGACA 1080

TTCATTTTAA AAGGTCTAAG GAAAAGCAGT GAATACAGCA GGAACAGAAA GACCATCATC 1140

CCCCGCTGCG TGCCCAACAT GGTGTGTCTG CACAAGTACA TCGTTTCTGA GGAGTCCGTA 1200

TTTCTTGTGC TGCAGCACGC GGAAGGTGGC AAACTCTGGT CATATATCAG TAAGTTTCTA 1260

AACAGAAGCC CTGAAGAAAG CTTTGACATC GGGGAAGTGA AAAAATCTAC ACTTACTAAA 1320

GTTCACCTGC AACAGCCAAC TTCTAGTCCT CAGGACAGCA GCAGCTTTGA ATCCAGAGGA 1380

AGTGATGGTG GAACCATTCA TAAAGTTTTG CCTTTGAAGA CTAGTCTTAC TCCAAGCTCT 1440

CAAGATGATA GCAACCAAGA TGAAGAAGGC CAAGATAGCT CTCCAAAATG GCCAGATTCG 1500

GGCTCAAGTT CAGAAGAAGA ATGCACTACT AGTTATTTGA CATTATGCAA TGAATATGGG 1560

CAAGAAAAGA TTGAACCAGG GTCATTGAAT GAAGAGTCTT TCATGAAGAT TGGAGGGAAT 1620

GGTGTTGATA CCAAAGTTAT TGAAAGCTTC CCAACACACC TTGCTGCTGA CAGTGACAGC 1680

CCCAGCACCC AGCAGATGGC TCACGAGCTG AAGTTCTTTG CTGGAGATGA TGCCGTAGAA 1740

GCAATTAGTT CTCCAGGAAC GTCAGATTCC CTTAATAGAT CTAAAAACAG TCCCATGGAA 1800

TTCTTTAGGA TAGATAGTAA GGATAGCACT AGTGAACTCC TAGGCCTTGA TTTTGGAGAA 1860

AAATTGTATA GTCTAAAGTC AGAGCCTTTG AAACCATTTT TCACTCTTCC AGATGGAGAC 1920

AGCACTTCCA GGAGTTTCAC TACTAGTGAA AGCAAGATAG AGTTTATAGC TCAGGACACC 1980

ATTAGCAGGG GCTCAGATGA CTCTGTCCCA GTTATTTCTT TTAAAGATGC TGCTTTTGAT 2040

GATGTCATTG GCACTGATGA AGGAAGGCCT GATCTTCTTG TAAATCTACC TGGTGAATTG 2100

GAGGCAACCA AAGATGGTGC AGCAGTGGGA CCTACTAAGT TTACACAGAC TAATATAGGC 2160

ATAATTGAAA GTAAACTATT GGAAGCCCCT GATGTTTTAT GCCTCAGGCT TAGTACTGAA 2220

CAATGCCAAG CAAGTGAGGA AGAAGGCACA GAGGAATTGA GTGATCCTTC TAGGCCTAAA 2280

TCCCATAGTA TAGCAGAGAA ACACAATGCA CAGGGGGATC TTGGGATGTT ATTTGTAGCA 2340

GCTGTTGATC ATAGTAGTTC AGGAGACATG TCTTTGTCAC ATAGCTCAGA TCCTAACTTC 2400

CAAGGACTTG GAGTGGTTGA GTCGGCAGTG ACTGCAAACA ACACTGAAGA AAGCTTATTC 2460

CGTATTTCTA ACCCACTCTC AGGTGCTAAT GAATATAATG TAAACACAGA CACTTTAAAA 2520

ACTGAAGAAG TATTGCTGTT TACAGATCAA ACTGAGGATT TGGCTAAAGA GGAACTGACT 2580

TTATTTCAGA GAGACTCAGC GACTAAGGGG GAGAGTGGAT TAGCACTAGA AGGAGACAAG 2640

GAAATACATC AGCTTTTTGA GGACCTTGAT AAAAAATTAG CACTAAACTC CAGGTTTTAC 2700

ATCCCCGAGG GCTGCATTCA AAGATGGGCA GCTGAAATGG TGGTAGCCCT TGATGCTTTA 2760

CATAGAGAGG GAATTGTGTG CCGCGATTTG AACCCAAACA ACATCTTATT GAATGATAGA 2820

GGACACATTC AGCTAACGTA TTTTAGCAGG TGGAGTGAGG TTGAAGATTC CTGTGACAGC 2880

GATGCCATAG AGAGAATGTA CTGTGCCCCA GAGGTTGGAG CAATCACAGA AGAAACAGAA 2940

GCCTGTGATT GGTGGAGTTT GGGTGCTGTC CTCTTTGAAC TTCTCACTGG CAAGACTCTG 3000

GTTGAGTGCC ATCCAGCAGG AATAAATACT CATACTACTT TGAACATGCC AGAATGTGTC 3060

TCTGAAGAGG CTCGCTCACT CATACAACAG CTCTTACAGT TCAACCCTGT GGAGCGTCTT 3120

GGTGCTGGAG TTGCTGGTGT TGAAGATATC AAATCTCACC CATTTTTTAA CCCTGTGGAT 3180

TGGGCAGAAC TGATGAGATG A 3201

Domain Profile

S: 210   kalqsvdkalslrravwslpEelikqWaaelvvaleaLHeegvlirDlnadniLldskGh  269

         +  +  dk+l+l+ + +++pE++i++Waae+vval+aLH+eg+++rDln++niLl+++Gh

Q: 884   QLFEDLDKKLALNSR-FYIPEGCIQRWAAEMVVALDALHREGIVCRDLNPNNILLNDRGH  942

         444455566655544.89******************************************

S: 270   llltYfgrwsevekscrreavdnlysAPEvgaiselteasDwWslGalLyelLtGkalae  329

         ++ltYf+rwseve+sc+++a++++y+APEvgai+e+tea+DwWslGa+L+elLtGk+l+e

Q: 943   IQLTYFSRWSEVEDSCDSDAIERMYCAPEVGAITEETEACDWWSLGAVLFELLTGKTLVE  1002

         ************************************************************

S: 330   ahPsgiqahtelqlPevvSeeAkdLleeLLqfePalRlGaGeagvdelkaHPFF  383

         +hP+gi++ht+l++Pe+vSeeA++L+++LLqf+P +RlGaG+agv+++k+HPFF

Q: 1003  CHPAGINTHTTLNMPECVSEEARSLIQQLLQFNPVERLGAGVAGVEDIKSHPFF  1056

         *****************************************************9

Domain Sequence
(FASTA)

QLFEDLDKKL ALNSRFYIPE GCIQRWAAEM VVALDALHRE GIVCRDLNPN NILLNDRGHI 60

QLTYFSRWSE VEDSCDSDAI ERMYCAPEVG AITEETEACD WWSLGAVLFE LLTGKTLVEC 120

HPAGINTHTT LNMPECVSEE ARSLIQQLLQ FNPVERLGAG VAGVEDIKSH PFF 173

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005769	; C:early endosome
GO:0005524	; F:ATP binding
GO:0035091	; F:phosphatidylinositol binding
GO:0004672	; F:protein kinase activity
GO:0007154	; P:cell communication

KEGG

cfa:490288

;

InterPros

IPR011009	; Kinase-like_dom.
IPR007330	; MIT.
IPR001683	; Phox.
IPR000719	; Prot_kinase_cat_dom.

Pfam

PF04212	; MIT; 1.
PF00069	; Pkinase; 1.
PF00787	; PX; 1.

SMARTs

SM00745	; MIT; 1.
SM00312	; PX; 1.

Prosites

PS50011	; PROTEIN_KINASE_DOM; 1.
PS50195	; PX; 1.

Prints

Created Date

20-Feb-2013