EKS-CAF-00212

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CAF-00212

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDKL	527.7	6.3E-159	5	288	284

Status

Unreviewed

Ensembl Protein

ENSCAFP00000021096

UniProt Accession

E2RRC1;

Protein Name

Protein Synonyms/Alias

Gene Name

CDKL1

Gene Synonyms/Alias

CDKL1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCAFG00000014292	ENSCAFP00000036431	ENSCAFT00000048347
ENSCAFG00000014292	ENSCAFP00000021096	ENSCAFT00000022713

Organism

Canis familiaris

Functional Description

Protein Length

358

Protein Sequence
(FASTA)

MMEKYEKIGK IGEGSYGVVF KCRNRDTGQI VAIKRFLESE DDPVIKKIAL REIRMLKQLK 60

HPNLVNLLEV FRRKRKLHLV FEYCDHTVLH ELDRHQRGVP EHLVKNITWQ TLQAVNFCHK 120

HDCIHRDVKP ENILITKHSV IKLCDFGFAR LLTGPSDYYT DYVATRWYRS PELLVGDTQY 180

GPPVDVWAIG CVFAELLSGV PLWPGKSDVD QLYLIRKTLG DLIPRHQQVF SMNQYFSGVK 240

IPDPEDMEPL ELKFPNISYP ALGLLKGCLH MNPAERLTCE QLLQHPYFDS MRETGDSAKE 300

LDRPTRKTLR QSRKHLPGVK VLQLQCLPQL TSSGFLPALD NKKYYWNMKK LNYHFPNI 358

Nucleotide Sequence
(FASTA)

ATGATGGAGA AGTATGAAAA AATCGGGAAA ATTGGCGAAG GATCCTATGG AGTTGTGTTC 60

AAGTGCAGAA ACAGGGACAC GGGTCAGATC GTAGCCATCA AGAGATTTTT GGAGTCAGAA 120

GATGACCCTG TCATAAAGAA AATCGCCCTT CGAGAAATCC GCATGCTCAA GCAACTCAAA 180

CATCCCAACC TCGTGAACCT TCTCGAAGTC TTCAGAAGGA AGCGGAAGCT TCACCTGGTG 240

TTTGAGTACT GTGACCACAC GGTTCTCCAT GAGCTGGATA GACACCAAAG AGGGGTACCA 300

GAACATCTTG TGAAGAACAT AACTTGGCAG ACGTTGCAAG CTGTGAATTT TTGCCATAAA 360

CACGATTGCA TACATAGAGA TGTGAAGCCA GAAAATATCC TCATCACAAA ACATTCAGTG 420

ATTAAGCTTT GTGACTTTGG ATTTGCCCGA CTTTTGACTG GACCCAGTGA CTACTACACA 480

GACTACGTGG CTACTAGGTG GTACCGCTCC CCAGAACTAT TGGTGGGGGA CACACAGTAT 540

GGCCCCCCAG TAGATGTTTG GGCAATTGGC TGTGTCTTTG CTGAGCTGCT GTCAGGGGTA 600

CCTCTGTGGC CAGGAAAATC AGATGTGGAT CAGCTCTATC TGATTCGGAA AACCTTGGGA 660

GATCTCATTC CTAGGCACCA ACAAGTATTT AGCATGAATC AGTACTTCAG TGGGGTGAAA 720

ATTCCAGACC CTGAAGATAT GGAACCACTT GAATTAAAAT TTCCAAACAT CTCTTATCCT 780

GCCCTCGGGC TCTTGAAGGG CTGTCTCCAC ATGAATCCTG CTGAGAGGCT GACCTGTGAA 840

CAGCTGTTGC AGCACCCCTA TTTTGACAGC ATGAGAGAAA CGGGGGATTC GGCCAAAGAA 900

CTTGACAGAC CCACAAGGAA GACCCTACGA CAGAGCCGAA AGCACCTGCC TGGGGTAAAA 960

GTGTTGCAGT TGCAGTGCCT ACCTCAGCTA ACTAGCAGTG GCTTCCTTCC AGCTCTGGAT 1020

AATAAGAAGT ACTACTGGAA TATGAAGAAA CTTAACTACC ATTTTCCAAA CATT 1074

Domain Profile

S: 1     yeklgkvGeGsyGvvlkcrnkdtgqivaikkfleseddkevkkialreikllkqlkhenl  60

         yek+gk+GeGsyGvv+kcrn+dtgqivaik+flesedd+++kkialrei++lkqlkh+nl

Q: 5     YEKIGKIGEGSYGVVFKCRNRDTGQIVAIKRFLESEDDPVIKKIALREIRMLKQLKHPNL  64

         9***********************************************************

S: 61    vnllevfrrkkklylvfeyvdktvldelerypnGveeelvkkilyqilkaiefchknnii  120

         vnllevfrrk+kl+lvfey+d+tvl+el+r+++Gv+e+lvk+i++q+l+a++fchk+++i

Q: 65    VNLLEVFRRKRKLHLVFEYCDHTVLHELDRHQRGVPEHLVKNITWQTLQAVNFCHKHDCI  124

         ************************************************************

S: 121   hrdikpenilisksgvvklcdfGfarllaapgdvytdyvatrwyrapellvgdtkyGksv  180

         hrd+kpenili+k++v+klcdfGfarll++p+d+ytdyvatrwyr+pellvgdt+yG++v

Q: 125   HRDVKPENILITKHSVIKLCDFGFARLLTGPSDYYTDYVATRWYRSPELLVGDTQYGPPV  184

         ************************************************************

S: 181   dvwaiGcllaelltGeplfpgksdvdqlykirktlGeliprhqkifsknevfaGvklpev  240

         dvwaiGc++aell+G pl+pgksdvdqly+irktlG+liprhq++fs+n++f+Gvk+p++

Q: 185   DVWAIGCVFAELLSGVPLWPGKSDVDQLYLIRKTLGDLIPRHQQVFSMNQYFSGVKIPDP  244

         ************************************************************

S: 241   edleslekkypklnevlldllkkclkldpaerlsceellkheyf  284

         ed+e+le k+p++++ +l llk+cl+++paerl+ce+ll+h+yf

Q: 245   EDMEPLELKFPNISYPALGLLKGCLHMNPAERLTCEQLLQHPYF  288

         *******************************************9

Domain Sequence
(FASTA)

YEKIGKIGEG SYGVVFKCRN RDTGQIVAIK RFLESEDDPV IKKIALREIR MLKQLKHPNL 60

VNLLEVFRRK RKLHLVFEYC DHTVLHELDR HQRGVPEHLV KNITWQTLQA VNFCHKHDCI 120

HRDVKPENIL ITKHSVIKLC DFGFARLLTG PSDYYTDYVA TRWYRSPELL VGDTQYGPPV 180

DVWAIGCVFA ELLSGVPLWP GKSDVDQLYL IRKTLGDLIP RHQQVFSMNQ YFSGVKIPDP 240

EDMEPLELKF PNISYPALGL LKGCLHMNPA ERLTCEQLLQ HPYF 284

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013