EKS-CAF-00097

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CAF-00097

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Atypical/PIKK	401.5	3.7E-120	2704	3023	320

Status

Unreviewed

Ensembl Protein

ENSCAFP00000021395

UniProt Accession

F1PEL7;

Protein Name

Protein Synonyms/Alias

Gene Name

Cfa.11489

Gene Synonyms/Alias

Cfa.11489;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCAFG00000014454	ENSCAFP00000021395	ENSCAFT00000023032
ENSCAFG00000014454	ENSCAFP00000035996	ENSCAFT00000048574

Organism

Canis familiaris

Functional Description

Protein Length

3065

Protein Sequence
(FASTA)

MSLALNDLLI CCRQLEHDRA TERRKEVEKF KRLIRDPETI QHLDRHSDSK QSKYLNWDAV 60

FRFLQKYVQK ETECLRTAKP SVSASTQATR QKKMQEISSL VKYFIKCANK RAPRLKCQEL 120

LNYIMDTVKD SFNGAVYGAD CSNILLKDIL SVRKYWCEIS QQQWLELFSV YFNLYLKPPQ 180

DMNRVLVARI IHAVTKGCCL QTDGLNSKFL DFFSKAIQHA RQEKSAAGLN HILAAFIIFL 240

KTLAGNFRIR VCQLGDEILP TLLYIWTQHR LNDSLKEVII ELFQLQIYMH HPKGAKTQEK 300

GAYESSKWQS ILYNLYDLLI NEISHIGSRG KYSSGSRNVA VKENLIELMA DICHQVFNED 360

TRSLEISQSY TTTQREFNDY SVPCKKKKIE LGWEVIKDHL QKSQSDFDLV PWLQITTQLI 420

SKYPSSLPNF ELSSLLMILY QLLPQRRHGE RTPYVLRCLM EVALCQGKKS NLEGSQKSDL 480

LKLWNKIWSV TFRGISSEQI QAENFGLLGA IIQGSLIEVD REFWKLFTGS ACRPSCPAVC 540

CLTLAMNICL VPETVRTGVE QNVGEVNRNF SLKELIMKWL LLYQLEDDFE DSSELPPVLH 600

SNFPHLAVEK ILVSLTMKNC KAAMNFLQRV PECEQHQKDE EEPSFSEVEE LFLKTTFDKM 660

GFLTIVKESA VEKQQSTGGL FVHQNLKESL DRYLLGLSEQ LLSNYSPETT DAETLIRCSS 720

LLVGVLGCYC SVSVITEEEA YTSELFQKAK SLMQCAGESI TLFKNKTHEE SRIVSLRNMM 780

NLCTSCLCNC MKPSPNKIAS RFFLRLLTSK LMNDIADICR SLASFIRKPF DFGEVESMED 840

DTDDNLMEME DQSSMNLFSD SPAGSASDAN VSGEGQSTIG AMNPLAEEHL SKQDLLFLDM 900

LKFLCVCVTT AQTSTVSFRA ADIRRKLLML IDSSVLDPSK SLHLHMYLVL LKELPGEEYP 960

LPMEEVVELL KPLSNVCSLY RRDQDVCKAV LNHIVHIVRN LCQGNMDAEN TRDAQGQFLT 1020

VIGAFWHLAK EGKCTFSVRM ALVKCLKTLL EADPYSKWAI LNVMGKDFPV NEVFPHFLAD 1080

NHHQVSMLAA ESINRLFQDM KHGGSSTLLK ALPLKLQQTA FENAYLKAQE GMIEVSCRAE 1140

NPEHLDEIYN RKSVLLMTVA VILCCSPVCE KQALFALCKS VKENGLEPHL IKKVLEKVSE 1200

TFGYRCLEDF MASHLDYLVL EWLNLQDTEN SLYSFPFILL NYTNVEDFYR SCYKVLIPHL 1260

VIRSRFDEVK SIANQIQEDW KSLLTHCFPK ILVNILPYFA YECTGDSGMA QQRETATKVY 1320

DMLKDENLLG KQIDHLFLSN LPEIVVELLM TLHEPATSGA SQSTDLCDFS GDLDPPPNPP 1380

HFPSHVIKAT FAYISNCHKT KLKSILEILS KSPDSYQKIL LAICEQATET NNVYKKHRIL 1440

KIYHLFVTLL LKDIKSALGG AWAFVLRDVI YTLIHYINKR VRPSRFMDVS LRSFSLCCDL 1500

LSRVCHTAVT YCKDALENHL HVIIGTLIPL VNDQMEVQDQ VLDLLKYLVI DNKDNENLYM 1560

TIKLLDPFPD HDVFKDLRIT QQKIKYSNGP FSLLEEINHF LSVSVYDALP LTRLEGLKDV 1620

CRQLAQHKDQ MADLMRASQD NPQDGIMVKL IVSLLQLCKM AVNHTGEREV LEAVGSCLGE 1680

VGPVDFSTIA IQHSRDISSI KASELFEDKE LQWTFITLTY LNNTLVEDCV KVRSAAVTCL 1740

KSILATKTGH SFWEIYKMTT DPMLIYLQPF RTSRKKFLEV PRLDKESPLE GLDDTSLWIP 1800

QSENHDIWIK RLTCAFLDSG GTKSEILQLL KPMCEVKADF CQTVLPYLIH DILLQDTNES 1860

WRNLLSTQIQ GFFTNCFRHS SPTSRSTTPA NLDSESEHFF RSCVDKKSQR TMLAVVDYMR 1920

RQKRPSIGTV FDDAFWLELN YLEVAKVAQS CAAHFTALFY AEIYADKKSM EEDKRNRSLT 1980

FEEASQNTAI SSLSEKSKEE TGISLQDLLL EIYRSIGEPD SLYGCGGGKM LQPLTRLRTY 2040

EHEAMWGKAL VTYDLETAIS SSTRQAGIIQ ALQNLGLCHI LSIYLKGLDH ENKECCAELQ 2100

ELHYQAAWRN MQWEHCISVN KGTEGISYHE SLYNALQSLR DREFSTFYES LRYARVKEVE 2160

ELCKGGLESV YSLYPTLSRL QAIGELENIG QLLSRSVTDR QPSEVYTKWR KHSQLLKDSD 2220

FSFQEPIMAL RTVILEILME KEMENSQREC FRDILTKHLV ELSILARTAK NTQLPERAIF 2280

QIKQYNPASC GVSEWQLEEA QVFWAKKEQS LALSILKQMI KKLDASCAQN DPDLSLLYTE 2340

CLRVCGTWLA ETCLENPAVI MQTYLEKAVE VARNYDGESS DELRNGKMKA FLSLARFSDT 2400

QYQRIENYMK SSEFENKQAL LKRAKEEVGL LREHKIQTNR NARYTVKVQR ELELDECALR 2460

ALKEDRKRFL CKAVENYISC LLSGEGHDMW IFRLCSLWLE NSGVPEVNGM MKRDGMKIPS 2520

YKFLPLMYQL AARMGTKMMG GLGFHEVLNN LISRISMEHP HHTLFIILAL ANANKDEFLT 2580

KPEAARRSRI TKNAPKQSSQ LDEEQDRTEA ANRIIHTIRS RRPHMVRSVE ALCDAYIILA 2640

NLDAAQWKTQ RKGINIPADQ PITKLKNLED VVVPTMEIKV DPTGEYRNLV TVQSFKAEFR 2700

LAGGLNLPKI IDCLGSDGKE RRQLVKGRDD LRQDAVMQQV FQMCNTLLQR NTETRKRKLT 2760

ICTYKVVPLS QRSGVLEWCT GTVPIGEFLV NNENGAHKRY RPEDLSALHC QKKMMDVQKK 2820

SFEEKYETFM DICQKFQPVF RYFCMEKFLD PAVWFEKRLA YTRSVATSSI VGYILGLGDR 2880

HVQNILINEQ SAELVHIDLG VAFEQGKILP TPETVPFRLT RDIVDGMGIT GVEGVFRRCC 2940

EKTMEVMRSS QETLLTIVEV LLYDPLFDWT MNPLKALYLQ QRLEDDTELH STPSGDDQEC 3000

KRSLSDSDQS FNKVAERVLM RLQEKLKGVE EGTVLSVGGQ VNLLIQQAMD PKNLSRLFPG 3060

WKAWV 3065

Nucleotide Sequence
(FASTA)

ATGAGTCTAG CGCTTAATGA TCTGCTTATT TGCTGCCGTC AACTAGAACA TGATAGAGCT 60

ACAGAACGAA GGAAAGAAGT TGAGAAATTC AAGCGCCTGA TTCGGGATCC TGAAACTATT 120

CAACATTTAG ATCGGCATTC AGATTCCAAA CAAAGCAAAT ATTTGAATTG GGATGCTGTT 180

TTTAGATTTT TACAGAAATA TGTTCAGAAA GAAACAGAAT GTCTGCGAAC AGCAAAACCA 240

AGTGTGTCAG CCTCAACACA AGCCACTAGG CAGAAAAAGA TGCAAGAAAT CAGTAGTTTG 300

GTCAAATATT TCATCAAATG TGCAAATAAA AGAGCGCCCA GACTAAAATG TCAAGAACTC 360

TTGAACTATA TCATGGATAC AGTGAAAGAT TCATTTAATG GTGCCGTTTA TGGAGCTGAC 420

TGTAGCAACA TTCTGCTCAA GGACATTCTT TCAGTGAGGA AATACTGGTG TGAAATATCT 480

CAGCAACAGT GGCTAGAATT GTTCTCTGTG TACTTCAATC TATACCTTAA ACCTCCACAA 540

GACATGAATA GAGTTTTAGT GGCTAGAATC ATTCATGCTG TGACTAAAGG ATGCTGTTTG 600

CAAACTGATG GATTAAATTC CAAATTTTTG GATTTCTTTT CCAAGGCTAT TCAGCATGCC 660

AGACAGGAAA AGAGCGCCGC AGGTCTAAAT CACATCTTAG CAGCGTTTAT CATCTTCCTC 720

AAGACATTGG CTGGTAACTT TCGAATTCGA GTGTGTCAAT TAGGAGATGA AATTCTTCCT 780

ACCTTGCTTT ATATTTGGAC TCAACATAGA CTTAATGATT CCTTAAAAGA AGTAATTATT 840

GAATTATTTC AACTACAAAT TTATATGCAT CATCCAAAGG GAGCCAAAAC CCAAGAAAAA 900

GGTGCTTATG AATCAAGTAA ATGGCAAAGT ATCTTATATA ACTTGTATGA TCTGCTAATT 960

AATGAGATAA GTCATATAGG AAGCAGAGGG AAATATTCTT CAGGCTCTCG TAATGTTGCT 1020

GTCAAGGAAA ACTTGATTGA GTTGATGGCG GATATTTGTC ACCAGGTCTT TAATGAAGAT 1080

ACTAGATCTC TGGAGATTTC TCAGTCTTAC ACTACCACAC AAAGAGAATT TAATGATTAC 1140

AGTGTACCTT GCAAAAAGAA GAAAATAGAA TTAGGCTGGG AAGTAATAAA AGATCATCTT 1200

CAGAAGTCAC AGAGTGATTT TGATCTTGTG CCTTGGTTAC AGATTACAAC CCAGTTAATA 1260

TCAAAATATC CTTCAAGCTT GCCTAACTTT GAGTTGTCAT CATTACTGAT GATACTATAC 1320

CAGCTTCTAC CTCAACGACG ACATGGGGAG CGCACACCGT ATGTGTTACG ATGCCTCATG 1380

GAAGTTGCAT TGTGTCAAGG CAAAAAGTCA AACTTAGAAG GCTCACAGAA ATCAGATTTG 1440

TTGAAACTCT GGAATAAAAT TTGGTCTGTT ACCTTTCGTG GTATAAGTTC TGAACAAATA 1500

CAAGCTGAAA ACTTTGGTTT ACTTGGAGCT ATAATTCAAG GCAGTTTAAT TGAGGTTGAT 1560

AGAGAATTCT GGAAGTTATT TACTGGGTCA GCCTGCAGAC CTTCATGTCC TGCAGTATGC 1620

TGCTTGACTC TGGCAATGAA CATCTGTTTG GTTCCAGAAA CTGTAAGAAC AGGAGTGGAG 1680

CAGAATGTAG GTGAAGTAAA TAGAAATTTT TCTTTGAAGG AATTGATAAT GAAATGGCTC 1740

TTACTCTATC AGTTAGAGGA TGACTTTGAA GATAGTTCAG AGCTGCCTCC AGTTCTTCAC 1800

AGTAATTTTC CTCATCTTGC AGTGGAGAAA ATTCTTGTGA GTCTCACTAT GAAAAATTGT 1860

AAAGCTGCAA TGAATTTTCT CCAAAGAGTG CCAGAATGTG AACAGCACCA AAAAGATGAA 1920

GAAGAGCCTT CGTTCTCAGA AGTTGAAGAA CTGTTTCTTA AGACAACTTT TGACAAGATG 1980

GGTTTTTTAA CCATCGTGAA AGAATCTGCT GTAGAGAAGC AGCAGTCTAC TGGAGGCCTT 2040

TTTGTCCACC AAAATCTCAA GGAATCTCTG GATCGCTATC TCCTGGGATT ATCAGAACAG 2100

CTCTTAAGTA ACTACTCACC TGAGACTACA GATGCAGAGA CGCTTATCCG GTGTTCAAGT 2160

CTTTTGGTGG GTGTTCTCGG CTGCTATTGC TCTGTAAGTG TAATAACAGA AGAGGAGGCA 2220

TATACATCAG AATTATTCCA GAAAGCCAAG TCTCTGATGC AGTGTGCAGG AGAAAGTATC 2280

ACTCTGTTTA AAAACAAGAC ACATGAGGAA TCTAGGATTG TTTCACTGAG AAATATGATG 2340

AACCTCTGTA CTAGTTGCTT GTGTAACTGT ATGAAGCCCA GTCCAAATAA GATAGCATCT 2400

CGATTTTTCC TGCGATTGTT GACATCAAAG CTAATGAATG ATATTGCAGA TATATGTAGA 2460

AGTTTGGCGT CCTTTATCAG AAAGCCATTT GACTTTGGAG AAGTAGAATC AATGGAAGAC 2520

GATACTGATG ACAATCTGAT GGAGATGGAA GATCAGTCAT CCATGAATCT ATTCAGTGAT 2580

TCCCCTGCTG GCAGTGCTAG TGATGCAAAT GTATCTGGAG AGGGCCAGAG TACTATTGGT 2640

GCCATGAATC CTTTAGCTGA AGAACATCTG TCAAAGCAAG ATCTGCTTTT CTTGGACATG 2700

CTCAAGTTCT TGTGTGTGTG TGTAACTACT GCTCAGACCA GCACTGTGTC ATTTAGAGCA 2760

GCTGACATTC GGAGGAAATT GTTAATGTTA ATTGATTCTA GCGTGCTCGA CCCTAGTAAA 2820

TCTCTCCATC TGCACATGTA TCTAGTGCTT TTGAAGGAGC TTCCTGGAGA AGAATATCCT 2880

TTGCCAATGG AAGAGGTTGT TGAACTTCTA AAACCACTAT CCAATGTGTG TTCTTTGTAT 2940

CGACGTGACC AGGATGTTTG TAAGGCAGTT TTAAACCACA TTGTTCATAT AGTGAGGAAC 3000

CTGTGTCAAG GCAATATGGA TGCTGAAAAC ACAAGGGATG CTCAAGGGCA GTTTCTAACA 3060

GTGATTGGAG CATTTTGGCA CTTAGCAAAA GAGGGGAAAT GCACTTTCTC TGTAAGAATG 3120

GCACTAGTAA AATGCCTTAA AACTTTGCTT GAGGCTGATC CTTATTCAAA ATGGGCTATT 3180

CTTAATGTGA TGGGAAAAGA CTTCCCTGTA AATGAAGTAT TTCCACATTT TCTTGCTGAT 3240

AATCATCATC AAGTTAGCAT GTTGGCTGCA GAGTCAATCA ATAGGTTATT CCAGGATATG 3300

AAACATGGAG GTTCTTCCAC ATTATTGAAG GCACTTCCTT TGAAGCTTCA GCAGACAGCT 3360

TTTGAAAATG CGTACTTGAA AGCTCAGGAA GGAATGATAG AAGTGTCCTG CAGAGCTGAG 3420

AACCCTGAAC ATTTGGATGA AATTTATAAC AGAAAATCTG TTTTACTGAT GACAGTAGCT 3480

GTGATTTTAT GCTGTAGCCC TGTCTGTGAA AAACAGGCTT TGTTCGCACT GTGCAAGTCT 3540

GTGAAAGAGA ATGGATTAGA ACCTCACCTC ATTAAAAAGG TTTTAGAGAA AGTTTCTGAA 3600

ACTTTTGGAT ATAGATGTTT AGAAGACTTC ATGGCTTCTC ATTTGGATTA TCTGGTTTTG 3660

GAATGGCTAA ATCTTCAAGA TACTGAAAAT AGTTTATATT CTTTCCCTTT TATTTTACTA 3720

AACTACACAA ATGTTGAGGA CTTCTATAGA TCATGTTACA AGGTTTTGAT CCCACATCTG 3780

GTGATTAGAA GTCGTTTTGA TGAGGTGAAG TCCATTGCTA ATCAGATTCA AGAGGATTGG 3840

AAAAGTCTTC TAACACACTG CTTTCCAAAG ATTCTTGTAA ATATTCTTCC TTACTTTGCC 3900

TATGAGTGTA CAGGAGATAG TGGGATGGCA CAGCAGAGAG AGACAGCTAC CAAAGTCTAC 3960

GATATGCTTA AAGATGAAAA CTTACTAGGA AAACAGATTG ATCATTTATT CCTTAGTAAC 4020

TTACCGGAGA TTGTTGTGGA GTTGTTGATG ACCTTACATG AACCAGCAAC TTCTGGTGCC 4080

AGCCAGAGCA CGGACCTCTG TGACTTTTCA GGGGATTTGG ATCCTCCTCC TAATCCACCT 4140

CATTTTCCAT CACATGTGAT TAAAGCAACA TTTGCCTATA TCAGCAATTG CCATAAAACC 4200

AAGCTTAAAA GCATTTTGGA AATTCTTTCC AAAAGTCCTG ATTCCTATCA GAAAATTCTC 4260

CTAGCCATAT GTGAGCAAGC CACTGAGACA AATAATGTTT ATAAAAAGCA CAGAATTCTT 4320

AAAATATATC ACCTGTTTGT TACTTTATTA CTGAAAGATA TAAAAAGTGC CTTAGGAGGA 4380

GCCTGGGCCT TTGTTCTTCG AGATGTTATC TATACTTTGA TTCATTATAT CAACAAAAGG 4440

GTTAGGCCTT CTCGTTTCAT GGATGTGTCG TTACGGAGCT TCTCCCTGTG TTGTGACCTG 4500

TTAAGCCGGG TTTGCCACAC AGCAGTCACG TACTGTAAGG ATGCTCTAGA AAATCATCTT 4560

CATGTCATCA TCGGTACACT TATACCCCTA GTGAATGATC AGATGGAAGT TCAGGACCAG 4620

GTATTGGACT TGTTGAAATA CTTAGTGATA GATAACAAGG ATAATGAAAA CCTATATATG 4680

ACAATTAAAC TTTTAGATCC TTTTCCTGAC CATGATGTCT TTAAGGATTT GCGCATTACT 4740

CAGCAGAAAA TTAAATACAG TAATGGACCC TTTTCACTTT TGGAGGAAAT AAACCATTTT 4800

CTCTCGGTGA GTGTTTATGA TGCACTCCCT TTGACAAGGC TTGAAGGCTT GAAGGATGTC 4860

TGCAGACAGC TCGCACAGCA TAAGGACCAG ATGGCAGACC TCATGAGAGC ATCTCAGGAT 4920

AACCCGCAGG ATGGCATAAT GGTGAAGCTC ATTGTCAGCT TGTTGCAGTT ATGCAAGATG 4980

GCAGTGAACC ACACTGGTGA AAGAGAAGTA TTAGAGGCTG TTGGAAGCTG CCTGGGAGAA 5040

GTGGGTCCTG TAGATTTCTC TACGATAGCC ATACAGCATA GCAGAGATAT ATCTTCTATT 5100

AAGGCCTCTG AGTTATTTGA AGATAAAGAA CTTCAGTGGA CCTTCATCAC ATTGACCTAC 5160

CTGAATAACA CACTGGTAGA AGATTGTGTC AAAGTACGAT CAGCTGCTGT TACCTGTTTG 5220

AAGAGCATTT TAGCCACAAA GACTGGACAT AGTTTCTGGG AGATTTATAA GATGACGACT 5280

GACCCCATGC TGATCTATCT ACAGCCTTTT AGAACATCGA GGAAAAAGTT TTTAGAAGTA 5340

CCCAGACTGG ATAAAGAAAG TCCTTTAGAA GGCCTGGATG ATACAAGCCT GTGGATTCCC 5400

CAAAGTGAAA ATCATGATAT TTGGATTAAA AGGCTGACTT GTGCTTTTTT GGATAGTGGA 5460

GGCACAAAAA GTGAAATTCT TCAATTATTA AAGCCAATGT GTGAAGTGAA AGCTGACTTT 5520

TGTCAGACTG TGCTTCCATA CTTGATTCAT GATATTTTAC TGCAAGATAC AAATGAGTCC 5580

TGGAGAAACC TGCTTTCTAC ACAGATTCAG GGATTCTTCA CTAATTGTTT CAGACACTCC 5640

TCACCAACGA GCCGATCCAC AACCCCTGCA AATTTGGATT CTGAGTCAGA GCACTTTTTC 5700

CGATCCTGTG TGGATAAAAA ATCACAAAGA ACAATGCTGG CTGTCGTGGA CTACATGAGG 5760

AGACAGAAGA GACCTTCCAT AGGAACAGTT TTCGATGATG CTTTCTGGCT GGAGTTGAAT 5820

TATCTAGAAG TTGCTAAGGT AGCTCAGTCC TGTGCCGCTC ACTTTACAGC ATTGTTCTAT 5880

GCAGAAATCT ACGCAGATAA GAAAAGCATG GAAGAAGACA AAAGAAACAG AAGTCTTACG 5940

TTTGAGGAAG CAAGCCAGAA TACAGCTATT TCTAGTTTGA GTGAAAAAAG TAAAGAAGAA 6000

ACTGGAATAA GTTTACAGGA TCTGCTTTTA GAAATCTACA GAAGTATAGG AGAGCCAGAC 6060

AGTCTGTATG GCTGTGGCGG AGGGAAAATG TTACAGCCCC TTACTAGACT GCGTACATAC 6120

GAACATGAAG CAATGTGGGG GAAAGCCCTG GTTACCTATG ACCTTGAGAC AGCAATCTCC 6180

TCATCAACCC GCCAGGCAGG AATAATTCAG GCCTTGCAGA ATTTGGGACT CTGCCATATT 6240

CTCTCCATCT ATTTAAAAGG ATTAGATCAT GAAAACAAGG AGTGCTGTGC CGAGCTACAG 6300

GAGCTCCACT ACCAAGCTGC GTGGAGGAAC ATGCAGTGGG AGCACTGCAT TTCTGTCAAC 6360

AAAGGAACAG AAGGAATCAG TTACCATGAA TCATTGTACA ATGCTCTCCA GTCTCTAAGA 6420

GATAGAGAAT TCTCCACATT TTATGAAAGT CTCAGATATG CCAGGGTGAA GGAAGTGGAA 6480

GAGCTGTGCA AGGGTGGCCT CGAGTCTGTG TACTCACTCT ACCCCACACT CAGCAGGCTG 6540

CAGGCCATCG GGGAGCTCGA AAACATCGGG CAGCTCCTCT CCAGATCAGT CACGGATAGG 6600

CAACCATCCG AAGTATACAC AAAGTGGCGG AAACACTCCC AGCTTCTCAA AGACAGTGAT 6660

TTCAGTTTCC AGGAGCCCAT CATGGCTCTC CGCACAGTCA TTTTGGAAAT CCTGATGGAA 6720

AAGGAAATGG AGAACTCCCA GAGAGAATGT TTTAGGGACA TTCTTACCAA GCACCTTGTA 6780

GAACTTTCCA TACTGGCCCG AACTGCCAAG AACACTCAGC TCCCTGAAAG AGCAATATTT 6840

CAAATTAAAC AGTATAATCC AGCAAGTTGT GGAGTCTCTG AGTGGCAGCT GGAGGAAGCA 6900

CAAGTATTTT GGGCAAAAAA GGAGCAGAGT CTTGCCCTAA GTATTCTCAA GCAAATGATC 6960

AAGAAGTTGG ATGCCAGTTG TGCACAGAAT GATCCCGACC TAAGCCTTCT GTACACAGAG 7020

TGTCTGAGGG TTTGTGGCAC CTGGTTAGCA GAAACTTGCC TAGAAAACCC TGCAGTGATT 7080

ATGCAGACCT ATCTAGAAAA GGCAGTGGAA GTTGCTAGAA ATTACGATGG AGAAAGCAGT 7140

GATGAACTTA GAAATGGAAA AATGAAAGCG TTTCTCTCAT TAGCACGGTT CTCAGATACA 7200

CAGTACCAGA GAATTGAAAA CTACATGAAA TCATCAGAGT TTGAAAACAA GCAGGCTCTT 7260

TTGAAAAGGG CCAAAGAGGA AGTGGGCCTT CTTAGGGAAC ATAAAATCCA GACCAACAGA 7320

AATGCAAGAT ACACAGTAAA GGTTCAGCGG GAGCTGGAGC TGGATGAATG TGCACTCCGT 7380

GCACTGAAAG AGGATCGTAA ACGTTTCTTA TGTAAAGCAG TTGAAAATTA CATCAGTTGC 7440

TTATTGAGTG GAGAAGGACA TGATATGTGG ATATTCCGTC TTTGTTCTCT CTGGCTTGAA 7500

AATTCCGGAG TTCCTGAAGT CAATGGCATG ATGAAGAGAG ATGGAATGAA GATTCCATCA 7560

TATAAATTTT TGCCTCTCAT GTACCAGTTG GCTGCCAGAA TGGGGACCAA AATGATGGGA 7620

GGCCTAGGAT TTCATGAAGT CCTCAATAAT CTTATCTCTA GAATTTCAAT GGAGCACCCC 7680

CATCACACTT TGTTTATTAT ACTGGCCTTA GCAAATGCAA ACAAAGATGA ATTTTTGACC 7740

AAACCAGAGG CAGCAAGAAG GAGTAGAATA ACTAAAAATG CACCTAAACA AAGCTCTCAG 7800

CTTGATGAGG AACAGGATCG AACAGAGGCT GCAAACAGAA TAATCCACAC TATCAGAAGT 7860

CGGAGACCTC ATATGGTCAG AAGTGTGGAA GCACTTTGTG ATGCTTACAT CATATTAGCA 7920

AACTTAGATG CCGCTCAGTG GAAGACTCAG AGAAAAGGCA TCAATATCCC AGCAGACCAG 7980

CCAATCACTA AACTGAAGAA TTTAGAAGAT GTTGTTGTTC CAACTATGGA AATTAAGGTG 8040

GACCCCACAG GAGAATACAG AAATCTGGTG ACTGTACAGT CATTTAAAGC AGAATTTCGT 8100

TTAGCAGGAG GTCTAAATTT ACCGAAAATA ATAGACTGTT TGGGGTCTGA TGGCAAGGAA 8160

AGGAGACAGC TCGTCAAGGG CCGTGATGAC CTGAGACAAG ACGCTGTCAT GCAGCAGGTT 8220

TTCCAGATGT GTAACACGTT ACTGCAGAGG AACACAGAGA CCAGGAAGAG GAAGCTGACT 8280

ATCTGCACGT ACAAGGTGGT TCCGCTTTCT CAGCGAAGCG GGGTTCTCGA ATGGTGCACG 8340

GGAACCGTCC CTATTGGTGA GTTTCTTGTC AACAATGAGA ATGGTGCTCA TAAGAGATAC 8400

AGGCCAGAGG ACTTGAGTGC CCTTCACTGC CAGAAGAAAA TGATGGATGT ACAAAAAAAG 8460

TCTTTTGAAG AGAAATATGA AACTTTCATG GATATCTGCC AAAAATTTCA GCCAGTTTTC 8520

CGTTACTTCT GCATGGAAAA GTTCTTGGAC CCAGCTGTTT GGTTTGAGAA GCGACTGGCT 8580

TATACTCGCA GTGTGGCCAC TTCCTCGATT GTTGGTTACA TACTTGGACT TGGTGATCGA 8640

CATGTGCAGA ATATCTTGAT AAATGAGCAG TCTGCAGAAC TTGTACATAT AGATTTGGGA 8700

GTTGCTTTTG AACAGGGTAA AATCCTCCCT ACTCCTGAAA CAGTTCCTTT CAGGCTCACC 8760

AGAGATATTG TGGATGGGAT GGGCATTACT GGTGTTGAAG GCGTCTTCAG AAGATGCTGT 8820

GAGAAAACCA TGGAGGTTAT GAGAAGCTCT CAGGAAACCC TGTTAACCAT TGTGGAGGTT 8880

CTCCTGTACG ACCCCCTGTT TGACTGGACT ATGAATCCTC TGAAAGCTTT GTATTTACAG 8940

CAGAGGCTGG AGGATGACAC TGAGCTCCAC TCCACTCCCA GTGGAGATGA CCAGGAATGC 9000

AAACGCAGTC TCAGTGACAG TGACCAGAGT TTCAACAAAG TAGCAGAGCG TGTCTTGATG 9060

AGATTACAGG AGAAACTGAA AGGAGTGGAA GAAGGAACGG TGCTCAGTGT GGGGGGACAG 9120

GTGAATCTGC TCATACAGCA AGCTATGGAC CCCAAAAATC TCAGCCGACT TTTCCCAGGA 9180

TGGAAAGCGT GGGTATGA 9198

Domain Profile

S: 13    skqkpkklllrGsdgkeypyLvkgkeDlrqdervlqlfslvNtlLakdketsrrkLkirt  72

          ++ pk +  +Gsdgke+++Lvkg++Dlrqd++++q+f+++NtlL++++et++rkL+i+t

Q: 2704  GLNLPKIIDCLGSDGKERRQLVKGRDDLRQDAVMQQVFQMCNTLLQRNTETRKRKLTICT  2763

         566799999***************************************************

S: 73    ykVvplstrsgliewventvsLkellkklvekkavlldqpisyrykdlstvqarkpklkh  132

         ykVvpls+rsg++ew+++tv+++e+l   v++++++++   +yr++dls+  ++k+++++

Q: 2764  YKVVPLSQRSGVLEWCTGTVPIGEFL---VNNENGAHK---RYRPEDLSALHCQKKMMDV  2817

         **************************...799999999...*******************

S: 133   lkls....levfkevlenlvpkdllkklllekfpspeewfelrkaytrslAvislvgyiL  188

         +k+s    +e f++++++++p  +++++++ekf++p++wfe+r aytrs+A++s+vgyiL

Q: 2818  QKKSfeekYETFMDICQKFQP--VFRYFCMEKFLDPAVWFEKRLAYTRSVATSSIVGYIL  2875

         *********************..9************************************

S: 189   gLgdrhlenllidqetgevvhidfgvafekaktqlkvpekvPFRLTrnivnalgvtgveG  248

         gLgdrh++n+li+++++e+vhid+gvafe++k+ l++pe+vPFRLTr+iv+++g+tgveG

Q: 2876  GLGDRHVQNILINEQSAELVHIDLGVAFEQGKI-LPTPETVPFRLTRDIVDGMGITGVEG  2934

         *********************************.**************************

S: 249   vfrasceavlrvlreskeklltiLevflydplvdwkk......kkktsketeeelaekak  302

         vfr++ce++++v+r+s+e+llti+ev+lydpl+dw++      + +++ e+++el+++ +

Q: 2935  VFRRCCEKTMEVMRSSQETLLTIVEVLLYDPLFDWTMnplkalYLQQRLEDDTELHSTPS  2994

         *******************************************9****************

S: 303   aealkikkllskvekaenavatrdlllle  331

          +++++k+ ls+ ++++n+va+r+l++l+

Q: 2995  GDDQECKRSLSDSDQSFNKVAERVLMRLQ  3023

         ************************99987

Domain Sequence
(FASTA)

GLNLPKIIDC LGSDGKERRQ LVKGRDDLRQ DAVMQQVFQM CNTLLQRNTE TRKRKLTICT 60

YKVVPLSQRS GVLEWCTGTV PIGEFLVNNE NGAHKRYRPE DLSALHCQKK MMDVQKKSFE 120

EKYETFMDIC QKFQPVFRYF CMEKFLDPAV WFEKRLAYTR SVATSSIVGY ILGLGDRHVQ 180

NILINEQSAE LVHIDLGVAF EQGKILPTPE TVPFRLTRDI VDGMGITGVE GVFRRCCEKT 240

MEVMRSSQET LLTIVEVLLY DPLFDWTMNP LKALYLQQRL EDDTELHSTP SGDDQECKRS 300

LSDSDQSFNK VAERVLMRLQ 320

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0000781	; C:chromosome, telomeric region
GO:0005819	; C:spindle
GO:0016303	; F:1-phosphatidylinositol-3-kinase activity
GO:0005524	; F:ATP binding
GO:0004677	; F:DNA-dependent protein kinase activity
GO:0007420	; P:brain development
GO:0007050	; P:cell cycle arrest
GO:0071480	; P:cellular response to gamma radiation
GO:0006975	; P:DNA damage induced protein phosphorylation
GO:0006281	; P:DNA repair
GO:0007292	; P:female gamete generation
GO:0031572	; P:G2/M transition DNA damage checkpoint
GO:0007507	; P:heart development
GO:0071044	; P:histone mRNA catabolic process
GO:0016572	; P:histone phosphorylation
GO:0008630	; P:intrinsic apoptotic signaling pathway in response to DNA damage response
GO:0042159	; P:lipoprotein catabolic process
GO:0007094	; P:mitotic cell cycle spindle assembly checkpoint
GO:0043066	; P:negative regulation of apoptotic process
GO:0030889	; P:negative regulation of B cell proliferation
GO:0051402	; P:neuron apoptotic process
GO:0018105	; P:peptidyl-serine phosphorylation
GO:0043517	; P:positive regulation of DNA damage response, signal transduction by p53 class mediator
GO:0043525	; P:positive regulation of neuron apoptotic process
GO:0002331	; P:pre-B cell allelic exclusion
GO:0090399	; P:replicative senescence
GO:0001756	; P:somitogenesis
GO:0000723	; P:telomere maintenance

KEGG

InterPros

IPR016024	; ARM-type_fold.
IPR015519	; ATM/Tel1.
IPR003152	; FATC.
IPR011009	; Kinase-like_dom.
IPR000403	; PI3/4_kinase_cat_dom.
IPR018936	; PI3/4_kinase_CS.
IPR003151	; PIK-rel_kinase_FAT.
IPR014009	; PIK_FAT.
IPR021668	; TAN.

Pfam

PF02259	; FAT; 1.
PF02260	; FATC; 1.
PF00454	; PI3_PI4_kinase; 1.
PF11640	; TAN; 1.

SMARTs

SM00146

; PI3Kc; 1.

Prosites

PS51189	; FAT; 1.
PS51190	; FATC; 1.
PS00915	; PI3_4_KINASE_1; 1.
PS00916	; PI3_4_KINASE_2; 1.
PS50290	; PI3_4_KINASE_3; 1.

Prints

Created Date

20-Feb-2013