EKS-CAF-00432

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CAF-00432

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/ULK	326.5	1.6E-97	4	254	251

Status

Unreviewed

Ensembl Protein

ENSCAFP00000035943

UniProt Accession

J9JHL2;

Protein Name

Protein Synonyms/Alias

Gene Name

STK36

Gene Synonyms/Alias

STK36;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCAFG00000014919	ENSCAFP00000021994	ENSCAFT00000023691
ENSCAFG00000014919	ENSCAFP00000035943	ENSCAFT00000046131

Organism

Canis familiaris

Functional Description

Protein Length

1319

Protein Sequence
(FASTA)

MEKYHVLEMI GEGSFGRVYK GRRKYSAQVV ALKFIPKLGR SEKELRNLQR EIEIMRGLRH 60

PNIVHMLDSF ETDKEVVVVT DYAEGELFQI LEDDGKLPED QVQAIAAQLV SALYYLHSHR 120

ILHRDMKPQN ILLAKGGGIK LCDFGFARAM STNTMVLTSI KGTPLYMSPE LVEERPYDHT 180

ADLWSVGCIL YELAVGTPPF YTTSIFQLVS LILKDPVRWP TTISPCFKSF LQGLLTKDPR 240

QRLSWPDLLH HPFIAGRVTI ITEPGGSDLG TPFTSHLPPE LQVLKEQQVH RLAPKGNRSR 300

ILRLACKRMA EEAKRKKHQN TGPALEQEDR TSKMASGTAP LPRLRATPQE PGLIAGILAS 360

EMKSSWAEWG AGETPPAPRE NQITQDCEQA DPELRPEVVG QQSIDAVDLE NEEPDSDDEW 420

QHLLKTGEPV PIQLKAPLTL LCNPDFCQRI QGQLHEAGGQ ILKDVPEDAS HILPALRVLS 480

SLLSSCSDSV PLYSFCREAG LPGLLLSLLR HSQESNSIQQ QCWYGTFLRD LMAVIQAYFA 540

CTFNLERSQT GDSLQVFQEA ANLFLDQLGK LLAQPDDSKQ TLRRDSLMCF TVLCEAMDGN 600

SWTISKAFYS SLLTTQRAVL DGLLHGLTVP QLSFHTPPGA PQVSQPLREQ SEDLPGAMSS 660

ALAAICTAPV GLPSCWEAKE QISRHLANQL SEDSNQLRPS LISGLQHPIL CLHLLKVLYS 720

CCHISERLCH LLGQEPLALE SLLMLVQGKV KVVDWEESTE VALYLLSLLV LQLQDLPPGM 780

EKLGNEIATL FTHSHIVSLV SAAACLLGQL GQQGVTFDLQ PVEWIAAASH ALSAPAEVRL 840

IPPGCCGFYD GLLILLLQLL TQPGKGSLLR DVADSEIWTV LWHRFSMALR LPEEVSPQEE 900

EPSLSRPQSP EPDWTLISPQ GMAALLSLAV ATFTQEPQLC LSHLSQRGSI LMSTLKHLLS 960

PSFLRQLGRA PQGAEFLPVV VLSVCQLLCF PFALDVDADL FRGVLADFVD SEVAAHLLQV 1020

CCHHLPLPQV ELPVSLLTRL ALTDLTSLNQ FVNTVAASPR TVISFLSVAL LGDQPLLTSD 1080

LLSLLAHTAR VLSPSHLSFI QELLAGSDES YRPLRSLLGH PEHSVRARTY GLLGHLLQHS 1140

MALRGALQSQ AGLLNLLLLG LGDKDPAVRR SASFAVGNAA YQAGPLGPAL AAAVPGMTQL 1200

LEDPQAGIRR NAVSALGNLG PEGLGAELLQ YQVPQRLLEM ACGDPQLNVK EAALIALRSL 1260

RQEPCIHQAD GFQGCSCYSW RCGAPSPIWA TRPCGHDGGP SWPQREQSTT ILASAGETA 1319

Nucleotide Sequence
(FASTA)

ATGGAAAAGT ACCACGTGTT GGAGATGATT GGAGAAGGCT CTTTTGGGAG GGTGTATAAG 60

GGTCGAAGAA AATACAGTGC TCAGGTGGTG GCCCTGAAGT TCATTCCAAA ATTAGGACGC 120

TCAGAGAAGG AGCTGAGAAA TCTGCAACGA GAGATTGAAA TCATGCGGGG TCTGCGGCAT 180

CCTAACATAG TGCATATGCT TGACAGCTTT GAAACTGACA AAGAGGTGGT GGTGGTGACA 240

GACTATGCTG AGGGAGAGCT CTTTCAGATC TTGGAAGATG ACGGAAAACT TCCTGAAGAC 300

CAGGTTCAAG CCATCGCTGC CCAGTTGGTG TCTGCTCTGT ACTATCTGCA TTCCCACCGC 360

ATCCTCCACC GAGACATGAA ACCGCAGAAC ATCCTTCTTG CCAAGGGTGG TGGTATCAAG 420

CTCTGTGACT TTGGATTTGC CCGGGCGATG AGCACCAACA CGATGGTGCT GACCTCCATC 480

AAAGGCACAC CACTTTATAT GTCTCCAGAG CTGGTGGAAG AGCGACCATA TGACCACACC 540

GCAGACCTCT GGTCTGTGGG CTGCATACTG TATGAGTTGG CTGTAGGCAC CCCTCCCTTC 600

TATACTACAA GCATCTTTCA GCTGGTCAGC CTCATTCTCA AGGACCCTGT GCGCTGGCCA 660

ACCACCATTA GTCCTTGCTT CAAGAGCTTC CTGCAGGGAC TGCTCACCAA AGACCCCAGG 720

CAGCGTCTGT CCTGGCCAGA CCTCTTACAT CATCCCTTTA TAGCTGGTCG TGTCACCATA 780

ATAACTGAAC CAGGAGGCTC AGATTTGGGC ACCCCATTCA CCAGTCATCT ACCCCCAGAA 840

CTTCAGGTCC TAAAGGAACA GCAGGTGCAT CGACTGGCCC CCAAGGGCAA TCGATCTCGC 900

ATCTTGCGAC TTGCCTGTAA GCGCATGGCT GAGGAGGCCA AGCGGAAGAA ACACCAGAAC 960

ACAGGACCTG CCCTTGAGCA AGAGGATAGG ACCAGCAAGA TGGCTTCTGG CACAGCCCCT 1020

CTGCCTAGAC TAAGAGCCAC TCCTCAGGAA CCAGGCCTCA TAGCTGGGAT CTTGGCCTCA 1080

GAAATGAAGA GCAGCTGGGC TGAATGGGGG GCTGGAGAGA CCCCCCCTGC ACCTCGGGAA 1140

AACCAGATCA CCCAGGATTG TGAACAAGCT GACCCAGAGC TGAGGCCAGA GGTGGTGGGC 1200

CAGCAGAGCA TTGATGCAGT GGACCTAGAA AATGAGGAGC CAGATAGCGA TGACGAGTGG 1260

CAACACCTGC TAAAGACTGG TGAACCTGTG CCCATCCAAC TGAAGGCTCC TCTCACTCTG 1320

CTGTGCAATC CTGACTTCTG CCAACGCATC CAGGGTCAGC TGCATGAGGC TGGAGGGCAG 1380

ATCCTGAAAG ATGTGCCGGA GGACGCTTCC CATATCCTTC CTGCACTTCG GGTCCTGAGC 1440

AGTCTTCTAT CCAGCTGCAG CGACTCTGTT CCCTTGTACT CCTTCTGCCG TGAGGCAGGG 1500

CTCCCCGGGC TCCTGCTCAG CCTGCTCAGA CACAGCCAGG AGAGCAACAG TATCCAGCAG 1560

CAATGTTGGT ATGGGACCTT CTTACGGGAC CTGATGGCTG TGATTCAGGC CTACTTTGCC 1620

TGTACCTTCA ATCTGGAGAG GAGCCAGACA GGTGACAGCC TACAGGTGTT TCAGGAGGCT 1680

GCCAACCTCT TTCTGGACCA GTTGGGGAAA CTGCTGGCCC AACCAGATGA CTCTAAGCAA 1740

ACTTTGCGGA GGGATAGCCT TATGTGCTTT ACTGTTCTGT GTGAAGCCAT GGATGGGAAC 1800

AGCTGGACCA TCTCCAAAGC CTTTTACTCC AGCCTGCTGA CAACGCAGCG GGCGGTGCTG 1860

GATGGGCTTC TTCACGGTTT GACAGTCCCC CAGCTCTCTT TCCACACCCC CCCAGGAGCC 1920

CCCCAAGTGA GCCAGCCACT GCGGGAGCAG AGTGAGGATC TGCCTGGAGC CATGTCCTCT 1980

GCGCTGGCAG CCATATGTAC TGCTCCTGTG GGGCTGCCCA GCTGCTGGGA GGCCAAGGAG 2040

CAGATCTCTA GGCATTTGGC GAACCAGCTC AGTGAAGACA GCAACCAACT GAGGCCATCC 2100

CTCATCTCTG GCTTGCAGCA TCCCATCCTG TGCCTACACC TTCTCAAGGT TCTCTACTCA 2160

TGCTGCCACA TCAGTGAGCG CCTGTGCCAT CTTCTAGGGC AAGAGCCCTT GGCCTTGGAG 2220

TCACTGTTGA TGTTGGTCCA GGGGAAGGTA AAGGTCGTGG ATTGGGAAGA GTCTACTGAA 2280

GTGGCTCTCT ACCTCCTCTC CCTTCTTGTC CTTCAGCTGC AAGATCTGCC TCCTGGAATG 2340

GAGAAGCTAG GCAATGAGAT TGCTACTCTC TTTACTCATT CACACATCGT CTCTCTTGTG 2400

AGTGCAGCAG CCTGTCTGTT GGGACAACTT GGGCAGCAAG GGGTGACCTT CGACCTCCAG 2460

CCTGTGGAGT GGATTGCTGC AGCCTCACAC GCTCTGTCTG CCCCTGCGGA GGTCCGGCTG 2520

ATTCCACCAG GTTGCTGTGG CTTCTATGAT GGCCTCCTCA TCCTCCTGCT ACAGCTTCTC 2580

ACCCAGCCAG GAAAGGGTAG CCTGTTAAGG GATGTGGCTG ACTCAGAAAT ATGGACCGTT 2640

CTGTGGCACC GGTTCTCAAT GGCTCTGAGG CTCCCTGAGG AGGTGTCTCC ACAGGAAGAG 2700

GAGCCATCAC TATCCAGGCC ACAAAGCCCA GAGCCAGACT GGACGCTGAT CTCACCCCAA 2760

GGCATGGCAG CCCTGCTGAG TCTGGCTGTG GCCACCTTCA CCCAGGAGCC CCAGTTATGC 2820

CTGAGCCACC TGTCACAGCG TGGAAGTATC CTCATGTCCA CTCTGAAGCA CCTGCTTTCC 2880

CCCAGCTTCC TGCGTCAGCT GGGCCGGGCG CCTCAGGGGG CTGAGTTTCT GCCCGTCGTG 2940

GTGCTCTCTG TCTGCCAGCT CCTCTGCTTC CCCTTCGCCC TGGATGTGGA TGCCGACCTC 3000

TTCAGAGGTG TCTTGGCTGA CTTTGTGGAC TCAGAAGTCG CGGCCCACCT GCTGCAGGTC 3060

TGCTGCCACC ATCTTCCGTT GCCTCAAGTC GAGTTGCCTG TCAGCCTCCT CACACGCCTG 3120

GCCCTCACGG ATCTCACGTC TCTCAACCAG TTTGTGAACA CAGTGGCTGC CTCCCCTAGA 3180

ACTGTCATCT CCTTCCTCTC AGTTGCCCTC CTGGGTGACC AGCCACTGCT AACCTCCGAC 3240

CTTCTCTCCT TGCTGGCCCA CACAGCCCGA GTGTTGTCTC CTAGCCACTT GTCCTTTATC 3300

CAAGAACTCC TGGCCGGCTC CGATGAGTCC TATCGGCCCC TGCGCAGTCT CCTGGGCCAC 3360

CCAGAGCATT CTGTGCGGGC CCGCACTTAT GGGCTCCTGG GACACTTACT GCAACACAGC 3420

ATGGCCCTGC GTGGGGCGCT GCAGAGCCAG GCCGGGCTGC TCAACCTTCT GCTATTGGGG 3480

CTTGGAGACA AGGACCCTGC GGTGCGGCGC AGTGCCAGTT TCGCTGTGGG CAATGCAGCC 3540

TACCAAGCTG GTCCCCTGGG ACCTGCCTTG GCCGCCGCGG TACCCGGTAT GACCCAGCTG 3600

CTGGAAGATC CTCAGGCTGG CATCCGGCGC AATGCCGTGT CTGCTCTGGG GAACCTGGGG 3660

CCTGAGGGAT TGGGGGCAGA GCTGTTACAG TACCAAGTAC CCCAGCGGCT CCTAGAAATG 3720

GCATGTGGAG ACCCCCAGCT GAATGTGAAG GAAGCTGCCC TCATTGCCCT CCGGAGCCTC 3780

CGACAGGAGC CCTGCATCCA TCAGGCTGAC GGATTTCAAG GATGCAGCTG CTACTCCTGG 3840

AGGTGCGGGG CACCTTCTCC AATTTGGGCC ACGAGGCCAT GTGGCCATGA TGGGGGCCCC 3900

TCATGGCCTC AGCGAGAACA GAGCACTACG ATATTGGCCT CCGCCGGGGA AACAGCTTAA 3960

Domain Profile

S: 1     ysleeeiGkGsfavvykgrlrkktsqvvAikvvekkkl.kkslenlekeikilkelkhen  59

         y++ e+iG+Gsf+ vykgr rk ++qvvA+k++ k ++ +k+l+nl++ei+i++ l+h+n

Q: 4     YHVLEMIGEGSFGRVYKGR-RKYSAQVVALKFIPKLGRsEKELRNLQREIEIMRGLRHPN  62

         8999***************.******************9*********************

S: 60    ivalldveetskevylvmeycaggdLakllkqkkeLsedtvreflqqlasalkaLhskki  119

         iv++ld++et+kev++v++y++ g+L ++l+++++L+ed+v+++++ql+sal++Lhs++i

Q: 63    IVHMLDSFETDKEVVVVTDYAE-GELFQILEDDGKLPEDQVQAIAAQLVSALYYLHSHRI  121

         **********************.*************************************

S: 120   vhrDlkPqniLlsyadakkelkkvtlkladFglarvlkeesma.atlkGsplYmaPEvvk  178

         +hrD+kPqniLl+        k +++kl+dFg+ar++++++m  +++kG+plYm+PE+v+

Q: 122   LHRDMKPQNILLA--------KGGGIKLCDFGFARAMSTNTMVlTSIKGTPLYMSPELVE  173

         *************........89********************9****************

S: 179   eqqydakaDlWSiGtilyellvGkpPfaaesiseLvekiekndvleppipkeisselkdl  238

         e+ yd++aDlWS+G+ilyel+vG+pPf+++si++Lv+ i k++v   ++p++is+++k++

Q: 174   ERPYDHTADLWSVGCILYELAVGTPPFYTTSIFQLVSLILKDPV---RWPTTISPCFKSF  230

         ********************************************...*************

S: 239   lqsLLqrdpkkRisfeelfahpfl  262

         lq+LL++dp++R+s+ +l++hpf+

Q: 231   LQGLLTKDPRQRLSWPDLLHHPFI  254

         **********************96

Domain Sequence
(FASTA)

YHVLEMIGEG SFGRVYKGRR KYSAQVVALK FIPKLGRSEK ELRNLQREIE IMRGLRHPNI 60

VHMLDSFETD KEVVVVTDYA EGELFQILED DGKLPEDQVQ AIAAQLVSAL YYLHSHRILH 120

RDMKPQNILL AKGGGIKLCD FGFARAMSTN TMVLTSIKGT PLYMSPELVE ERPYDHTADL 180

WSVGCILYEL AVGTPPFYTT SIFQLVSLIL KDPVRWPTTI SPCFKSFLQG LLTKDPRQRL 240

SWPDLLHHPF I 251

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011989	; ARM-like.
IPR016024	; ARM-type_fold.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013