EKS-CAF-00348

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CAF-00348

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/PEK	360.1	1.1E-107	167	581	415

Status

Unreviewed

Ensembl Protein

ENSCAFP00000037595

UniProt Accession

J9NSB6;

Protein Name

Protein Synonyms/Alias

Gene Name

Cfa.8910

Gene Synonyms/Alias

Cfa.8910;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCAFG00000015665	ENSCAFP00000037595	ENSCAFT00000050124
ENSCAFG00000015665	ENSCAFP00000023026	ENSCAFT00000024820

Organism

Canis familiaris

Functional Description

Protein Length

632

Protein Sequence
(FASTA)

MLGGSSGARE REAEGDGAEA VPAPPAIEFP ADGSDPKYDE SDVPAELQVL KGPLQQPTFP 60

FAVANQLLLV SLLEHLSHVH EPNPLRSRQV FKLLCQTFIK MGLLSSFTCS DEFSSLRLHH 120

NRAITHLMRS AKERVRQDPC EDNSHTQKIR SREIAFEAQT SRYLNEFEEL AVLGKGGYGR 180

VYKVRNKLDG QYYAIKKILI NGATKTDCMK VLREVKVLAG LQHPNIVGYH TAWIEHVHVT 240

HAQADRISIQ LPSLEVISDE EGDRYVNSKN DESNSSSIIF AEFTSGKDKS LGKSGIENRN 300

NRLVNYSTSL IPRDTSEFES PSFLQRNGLA DLPSSSIIEH QLPLRHHSDL EENFTSTGES 360

SENLSLLGQT EVQYHLMLHI QMQLCELSLW DWIVERNQRG RQYVDESACP YVMASVATKI 420

FQELVEGVFY IHNMGIVHRD LKPRNIFLHG PDQQVKIGDF GLACTDIIQK NTDWIGRDGK 480

RPPTHTSRVG TCLYASPEQL EGSDYDAKSD MYSLGVILLE LFQPFGTEME RVHILTGLRS 540

GQIPDSLSKR CPVQAKYIQH LTRRNASQRP SALQLLQSEL FHLNSKQVNL TLQMKILEQE 600

KEIEELKKQL SLLSQDKGAK DDMKDGTVPV LP 632

Nucleotide Sequence
(FASTA)

ATGCTGGGGG GCAGCTCCGG TGCCCGAGAG CGCGAGGCGG AGGGCGACGG GGCGGAGGCT 60

GTGCCTGCGC CTCCTGCCAT CGAGTTCCCG GCCGACGGCT CGGACCCCAA GTATGATGAA 120

TCTGATGTCC CAGCAGAACT CCAAGTATTA AAAGGACCCC TACAACAGCC GACTTTCCCT 180

TTTGCAGTTG CAAACCAACT CTTGCTCGTC TCTTTGCTGG AGCACTTGAG CCATGTGCAT 240

GAACCAAACC CGCTCCGTTC AAGACAGGTG TTTAAATTGC TTTGCCAGAC CTTTATCAAA 300

ATGGGGCTGC TGTCTTCTTT CACCTGTAGT GATGAGTTTA GCTCATTGAG GCTACATCAC 360

AACAGAGCTA TTACTCATTT AATGAGATCT GCTAAAGAGA GAGTTCGTCA GGATCCTTGT 420

GAAGATAATT CTCATACCCA GAAGATCAGA TCAAGGGAAA TAGCCTTTGA AGCACAGACT 480

TCACGTTACC TAAATGAATT TGAAGAGCTT GCTGTCTTAG GCAAAGGTGG ATACGGAAGA 540

GTGTACAAGG TCAGGAATAA ATTAGATGGT CAGTATTATG CAATTAAAAA AATCCTGATT 600

AATGGTGCAA CTAAAACAGA TTGTATGAAG GTACTACGGG AAGTGAAGGT GCTGGCAGGC 660

CTTCAGCATC CTAACATAGT AGGCTATCAC ACTGCTTGGA TAGAACATGT TCACGTGACC 720

CATGCACAAG CAGATCGAAT TTCTATTCAG CTGCCATCTC TGGAAGTGAT CTCTGACGAG 780

GAGGGTGACA GGTATGTGAA TAGTAAAAAT GATGAAAGTA ACAGCTCATC CATTATCTTC 840

GCCGAGTTCA CCTCAGGAAA AGACAAATCC TTAGGAAAAT CTGGCATTGA AAATCGGAAT 900

AATAGATTGG TGAACTACAG CACCAGTTTA ATCCCCAGAG ACACCAGTGA ATTTGAATCA 960

CCCAGTTTTC TCCAAAGAAA TGGTTTGGCT GATTTGCCTT CCAGCTCAAT TATTGAACAT 1020

CAGCTGCCAC TTAGGCATCA TTCCGACTTA GAAGAGAATT TCACATCCAC TGGGGAATCT 1080

TCTGAAAACT TAAGTTTGTT GGGGCAGACA GAGGTGCAGT ACCACTTGAT GCTGCACATC 1140

CAGATGCAGC TGTGTGAGCT CTCCCTGTGG GACTGGATAG TGGAGAGAAA CCAGCGGGGT 1200

CGGCAGTATG TGGACGAATC TGCATGTCCT TATGTCATGG CCAGTGTTGC AACAAAGATT 1260

TTTCAAGAAC TGGTGGAAGG TGTATTTTAC ATACATAACA TGGGAATCGT ACACAGAGAT 1320

CTGAAGCCAA GAAATATTTT TCTTCATGGC CCTGATCAGC AAGTAAAAAT AGGAGACTTT 1380

GGTCTGGCCT GCACAGACAT CATTCAAAAG AACACAGACT GGATCGGTAG AGATGGGAAG 1440

AGGCCACCCA CACACACTTC CAGAGTGGGT ACTTGTCTAT ACGCTTCACC TGAGCAGTTG 1500

GAAGGATCCG ACTATGACGC CAAGTCAGAT ATGTACAGCT TGGGTGTGAT CCTGCTAGAG 1560

CTCTTTCAGC CATTTGGAAC AGAAATGGAG CGAGTACACA TTTTAACAGG TTTAAGAAGT 1620

GGTCAGATAC CTGACTCCCT CAGTAAGAGG TGTCCCGTGC AAGCCAAGTA CATCCAGCAC 1680

TTAACTAGAA GGAATGCATC TCAGAGACCA TCTGCTCTTC AGCTGCTGCA AAGTGAACTT 1740

TTCCACTTGA ATAGTAAACA GGTTAACCTC ACCCTACAGA TGAAAATACT AGAGCAAGAA 1800

AAAGAAATCG AAGAACTAAA GAAGCAGCTG AGTCTCCTTT CTCAGGACAA AGGGGCCAAG 1860

GATGATATGA AGGATGGGAC TGTGCCCGTC CTGCCTTAA 1899

Domain Profile

S: 1     feeikvlGkGgfgvVlkaknkldkkeyaikriklnkakke.lekverevkaLaklehpni  59

         fee++vlGkGg+g+V+k++nkld+++yaik+i +n a+k+ ++kv+revk+La l+hpni

Q: 167   FEELAVLGKGGYGRVYKVRNKLDGQYYAIKKILINGATKTdCMKVLREVKVLAGLQHPNI  226

         899*********************************************************

S: 60    vrYfaawleekeesl...............................tdsseveaeaelee  88

         v Y++aw+e+ +                                  +

Q: 227   VGYHTAWIEHVHVTHaqadrisiqlpslevisdeegdryvnskndeS-------------  273

         ************98866677776666666555555555555555551.............

S: 89    sesseesdtk..................................................  98

Q: 274   ---------Nsssiifaeftsgkdkslgksgienrnnrlvnystsliprdtsefespsfl  324

         .........044445555555555555555555777777777777777777777777888

S: 99    ....................................................llyiqmel  106

                                                             +l+iqm+l

Q: 325   qrngladlpsssiiehqlplrhhsdleenftstgessenlsllgqtevqyhlMLHIQMQL  384

         8888888888888888888888888888888899**************************

S: 107   ceketLkdwiderk......llesrselvm.....rlfkqllegleylHskgliHrdLkp  155

         ce  +L+dwi er+      ++es++ +vm     ++f++l+eg+ y+H++g++HrdLkp

Q: 385   CE-LSLWDWIVERNqrgrqyVDESACPYVMasvatKIFQELVEGVFYIHNMGIVHRDLKP  443

         **.*********999999999999999999******************************

S: 156   sniFld.sddqvKigDFgLatalaealkedvkqdaqskeakhtgqvgtklymsPeqleks  214

         +niFl+  d+qvKigDFgLa++++ ++++d+  ++ ++ ++ht++vgt+ly+sPeqle+s

Q: 444   RNIFLHgPDQQVKIGDFGLACTDIIQKNTDWIGRDGKRPPTHTSRVGTCLYASPEQLEGS  503

         ******99****************************************************

S: 215   qYnkkvDifsLGlilfeLlypfstemervetltelrdgkipedfddkvpkekkllqklls  274

         +Y++k+D++sLG+il+eL++pf temerv++lt lr+g+ip+++++++p+++k++q+l++

Q: 504   DYDAKSDMYSLGVILLELFQPFGTEMERVHILTGLRSGQIPDSLSKRCPVQAKYIQHLTR  563

         ************************************************************

S: 275   rdpkeRpsasellksell  292

         r++++Rpsa +ll+sel+

Q: 564   RNASQRPSALQLLQSELF  581

         ***************986

Domain Sequence
(FASTA)

FEELAVLGKG GYGRVYKVRN KLDGQYYAIK KILINGATKT DCMKVLREVK VLAGLQHPNI 60

VGYHTAWIEH VHVTHAQADR ISIQLPSLEV ISDEEGDRYV NSKNDESNSS SIIFAEFTSG 120

KDKSLGKSGI ENRNNRLVNY STSLIPRDTS EFESPSFLQR NGLADLPSSS IIEHQLPLRH 180

HSDLEENFTS TGESSENLSL LGQTEVQYHL MLHIQMQLCE LSLWDWIVER NQRGRQYVDE 240

SACPYVMASV ATKIFQELVE GVFYIHNMGI VHRDLKPRNI FLHGPDQQVK IGDFGLACTD 300

IIQKNTDWIG RDGKRPPTHT SRVGTCLYAS PEQLEGSDYD AKSDMYSLGV ILLELFQPFG 360

TEMERVHILT GLRSGQIPDS LSKRCPVQAK YIQHLTRRNA SQRPSALQLL QSELF 415

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xiphophorus maculatus"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0006950	; P:response to stress

KEGG

InterPros

IPR015516	; Haem-reg_EIF2A_Kinase.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 2.

SMARTs

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013