EKS-CAF-00014

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CAF-00014

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/PHK	528.4	4.2E-159	24	291	268

Status

Unreviewed

Ensembl Protein

ENSCAFP00000024512

UniProt Accession

E2R3E4;

Protein Name

Protein Synonyms/Alias

Gene Name

PHKG2

Gene Synonyms/Alias

PHKG2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCAFG00000016653	ENSCAFP00000024512	ENSCAFT00000026395

Organism

Canis familiaris

Functional Description

Protein Length

406

Protein Sequence
(FASTA)

MTLDVGPEDE LPDWAAAKEF YQKYDPKDVI GRGVSSVVRR CVHRATGHEF AVKIMEVTAE 60

RLSPEQLEEV REATRRETHI LRQVAGHPHI ITLIDSYESS SFMFLVFDLM RKGELFDYLT 120

EKVALSEKET RSIMRSLLEA VSFLHANNIV HRDLKPENIL LDDNMQIRLS DFGFSCHLEP 180

GEKLRELCGT PGYLAPEILK CSMDETHPGY SKEVDLWACG VILFTLLAGS PPFWHRRQIL 240

MLRMIMEGQY QFSSPEWDDR SNTVKDLISK LLQVDPEERL TAEQALQHPF FERCEGSQPW 300

NLTPRQRFRV AVWTVLAAGR VALSTQRVRP LTKSALLRDP YALRPVRRLI DSCAFRLYGH 360

WVKKGEQQNR AALFQHQPPG PFPIMGPEEE GDSAAISEED AMLALG 406

Nucleotide Sequence
(FASTA)

ATGACGCTGG ACGTGGGGCC GGAGGATGAG CTGCCCGACT GGGCTGCGGC CAAAGAGTTT 60

TACCAGAAGT ACGACCCTAA GGACGTCATT GGCAGAGGAG TGAGCTCCGT GGTGCGCCGT 120

TGCGTTCATC GAGCTACTGG CCATGAGTTT GCGGTGAAGA TCATGGAGGT GACAGCTGAG 180

CGACTAAGTC CTGAACAGCT AGAGGAGGTG CGAGAAGCCA CGCGGCGAGA GACGCACATC 240

CTTCGCCAGG TCGCCGGCCA CCCCCACATC ATCACTCTCA TCGATTCCTA CGAGTCTTCT 300

AGCTTCATGT TCCTGGTGTT TGACCTGATG CGGAAGGGAG AGCTGTTTGA CTATCTCACA 360

GAGAAAGTGG CCCTCTCAGA AAAGGAGACC AGGTCCATCA TGAGGTCTCT GCTGGAAGCA 420

GTGAGCTTTC TCCATGCTAA CAACATTGTG CACCGAGACT TGAAGCCTGA GAATATTCTC 480

CTAGATGACA ATATGCAGAT CCGACTTTCA GATTTTGGGT TCTCCTGCCA CCTGGAACCT 540

GGCGAGAAGC TCCGAGAGTT GTGTGGGACC CCAGGCTACC TAGCACCAGA GATCCTTAAA 600

TGCTCCATGG ATGAGACCCA CCCCGGCTAC AGCAAGGAGG TTGACCTCTG GGCCTGTGGG 660

GTGATTTTGT TTACACTCCT GGCTGGCTCA CCACCATTCT GGCACCGACG TCAGATCCTG 720

ATGTTACGCA TGATCATGGA GGGCCAGTAC CAGTTTAGTT CACCTGAGTG GGATGACCGT 780

TCCAACACTG TAAAGGACCT GATCTCAAAG CTGCTACAGG TGGATCCTGA GGAGCGCCTG 840

ACAGCTGAGC AAGCCCTACA GCACCCCTTC TTTGAGCGTT GTGAAGGCAG CCAACCCTGG 900

AACCTCACCC CCCGCCAGCG GTTCCGGGTG GCAGTGTGGA CTGTGCTTGC TGCTGGACGA 960

GTGGCCTTAA GCACCCAGCG TGTCCGGCCA CTGACCAAGA GTGCACTGTT GAGGGACCCT 1020

TATGCGCTGC GGCCAGTGCG GCGCCTCATT GACAGTTGTG CCTTCCGGCT CTATGGGCAC 1080

TGGGTGAAGA AGGGTGAGCA ACAGAACCGA GCCGCGCTCT TCCAGCACCA GCCCCCTGGG 1140

CCTTTTCCCA TCATGGGCCC TGAAGAGGAG GGGGACTCAG CTGCTATCTC TGAGGAGGAC 1200

GCCATGCTGG CACTGGGCTA G 1221

Domain Profile

S: 1     yepkeilGrGvssvvrrciekatgqefavkiidvsaeklseeevkelreatlkeveilrq  60

         y+pk+++GrGvssvvrrc+++atg+efavki++v+ae+ls+e+++e+reat++e++ilrq

Q: 24    YDPKDVIGRGVSSVVRRCVHRATGHEFAVKIMEVTAERLSPEQLEEVREATRRETHILRQ  83

         9***********************************************************

S: 61    vsGhpsiiklkdvyesssflflvfdlmkkGelfdyltekvtlseketrkimralleavey  120

         v+Ghp+ii+l+d+yesssf+flvfdlm+kGelfdyltekv+lseketr+imr+lleav++

Q: 84    VAGHPHIITLIDSYESSSFMFLVFDLMRKGELFDYLTEKVALSEKETRSIMRSLLEAVSF  143

         ************************************************************

S: 121   lhaknivhrdlkpenillddneniklsdfGfstqleeGeklrelcGtpgylapeilkcsm  180

         lha+nivhrdlkpenillddn++i+lsdfGfs++le+GeklrelcGtpgylapeilkcsm

Q: 144   LHANNIVHRDLKPENILLDDNMQIRLSDFGFSCHLEPGEKLRELCGTPGYLAPEILKCSM  203

         ************************************************************

S: 181   deeapGyskevdlwalGvilytllaGsppfwhrkqllmlrlimeGkyqftspewddisee  240

         de++pGyskevdlwa+Gvil+tllaGsppfwhr+q+lmlr+imeG+yqf+spewdd+s++

Q: 204   DETHPGYSKEVDLWACGVILFTLLAGSPPFWHRRQILMLRMIMEGQYQFSSPEWDDRSNT  263

         ************************************************************

S: 241   vkdliskllvvdpekrltaeealahpff  268

         vkdliskll+vdpe+rltae+al+hpff

Q: 264   VKDLISKLLQVDPEERLTAEQALQHPFF  291

         ***************************8

Domain Sequence
(FASTA)

YDPKDVIGRG VSSVVRRCVH RATGHEFAVK IMEVTAERLS PEQLEEVREA TRRETHILRQ 60

VAGHPHIITL IDSYESSSFM FLVFDLMRKG ELFDYLTEKV ALSEKETRSI MRSLLEAVSF 120

LHANNIVHRD LKPENILLDD NMQIRLSDFG FSCHLEPGEK LRELCGTPGY LAPEILKCSM 180

DETHPGYSKE VDLWACGVIL FTLLAGSPPF WHRRQILMLR MIMEGQYQFS SPEWDDRSNT 240

VKDLISKLLQ VDPEERLTAE QALQHPFF 268

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005964	; C:phosphorylase kinase complex
GO:0005524	; F:ATP binding
GO:0004689	; F:phosphorylase kinase activity
GO:0005978	; P:glycogen biosynthetic process

KEGG

cfa:607275

;

InterPros

IPR020636	; Ca/CaM-dep_Ca-dep_prot_Kinase.
IPR011009	; Kinase-like_dom.
IPR002291	; Phosph_kin_gamma.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

PR01049

; PHOSPHBKNASE.

Created Date

20-Feb-2013