EKS-CAF-00247

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CAF-00247

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/CAMKL	388.3	1.6E-116	56	307	252

Status

Unreviewed

Ensembl Protein

ENSCAFP00000026984

UniProt Accession

F1P9C6;

Protein Name

Protein Synonyms/Alias

Gene Name

MARK3

Gene Synonyms/Alias

MARK3;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCAFG00000018257	ENSCAFP00000026984	ENSCAFT00000029020

Organism

Canis familiaris

Functional Description

Protein Length

746

Protein Sequence
(FASTA)

MSTRTPLPTV NERDTENHTS HGDGRQEVTS RTGRSGARCR NSIASCADEQ PHIGNYRLLK 60

TIGKGNFAKV KLARHILTGR EVAIKIIDKT QLNPTSLQKL FREVRIMKIL NHPNIVKLFE 120

VIETDKTLYL IMEYASGGEV FDYLVAHGRM KEKEARAKFR QIVSAVQYCH QKRIVHRDLK 180

AENLLLDADM NIKIADFGFS NEFTVGSKLD TFCGSPPYAA PELFQGKKYD GPEVDVWSLG 240

VILYTLVSGS LPFDGQNLKE LRERVLRGKY RIPFYMSTDC ENLLKRFLVL NPIKRGTLEQ 300

IMKDRWINAG HEEDELKPFV EPELDISDQK RIDIMVGMGY SQEEIQESLS KMKYDEITAT 360

YLLLGRKSSE LDASDSSSSS NLSLAKVRPS SDLNNSTGQS PHHKVQRSVS SSQKQRRYSD 420

HAGPAIPSVV AYPKRSQTST ADSDLKEDGI PSRKSSGSAV GGKGIAPASP MLGNASNPNK 480

ADIPERKKSS TVPSTNTASG GMTRRNTYVC SERTTADRHS VIQNGKENST IPDPRTPVAS 540

THSVSSAATP DRLRFPRGTA SRSTFHGQPR ERRTATYNGP PASPSLSHEA TPLSQTRSRG 600

STNLFSKLTS KLTRRNMSFR FIKRLPTEYE RNGRYEGSSR NVSAEQKDEN KEAKPRSLRF 660

TWSMKTTSSM DPNDMMREIR KVLDANNCDY EQRERFLLFC VHGDGHAENL VQWEMEAIKG 720

EVCPPGDLRR KGNRSLRGPM WKDARS 746

Nucleotide Sequence
(FASTA)

ATGTCCACTA GGACCCCGCT GCCAACGGTG AATGAAAGAG ACACTGAGAA CCACACGTCA 60

CATGGAGATG GGCGGCAAGA AGTTACCTCT CGCACTGGGC GCTCTGGAGC TAGGTGTAGA 120

AACTCTATAG CTTCCTGTGC TGATGAACAA CCTCACATCG GAAACTACAG ACTATTGAAA 180

ACAATCGGCA AGGGGAATTT TGCAAAAGTG AAATTGGCAA GACACATCCT TACAGGCAGA 240

GAGGTTGCAA TAAAAATAAT TGACAAAACT CAGTTGAATC CAACAAGTCT ACAAAAGCTC 300

TTCAGAGAAG TAAGAATAAT GAAGATTTTA AATCATCCAA ACATAGTGAA GTTGTTTGAA 360

GTCATTGAAA CTGACAAAAC ACTCTACCTA ATCATGGAGT ATGCAAGTGG AGGTGAAGTG 420

TTTGACTATT TGGTCGCACA TGGAAGAATG AAGGAAAAAG AAGCAAGAGC TAAATTTAGA 480

CAGATTGTAT CTGCAGTCCA GTACTGCCAC CAAAAGCGGA TTGTTCACAG AGACCTCAAG 540

GCCGAAAATC TATTGTTAGA TGCTGATATG AACATTAAAA TAGCTGACTT TGGTTTTAGC 600

AATGAATTTA CTGTTGGCAG TAAACTGGAT ACGTTTTGTG GCAGTCCTCC ATATGCAGCC 660

CCAGAGCTCT TCCAGGGCAA GAAATATGAT GGGCCGGAAG TTGACGTGTG GAGCCTTGGC 720

GTAATTCTCT ACACTCTAGT CAGCGGGTCA CTCCCCTTTG ATGGACAGAA CCTAAAGGAA 780

CTGAGAGAAA GAGTATTAAG AGGGAAATAC AGAATCCCTT TCTACATGTC CACAGACTGT 840

GAAAACCTTC TCAAACGTTT CCTGGTGCTA AATCCAATAA AACGAGGCAC TCTAGAGCAA 900

ATCATGAAGG ACAGATGGAT CAATGCAGGG CATGAAGAAG ATGAACTTAA ACCATTTGTT 960

GAACCAGAAC TAGACATCTC AGACCAGAAA AGAATAGATA TTATGGTGGG AATGGGATAT 1020

TCACAAGAAG AAATTCAAGA ATCTCTTAGT AAAATGAAAT ATGATGAGAT CACAGCTACG 1080

TATTTGCTGT TGGGGAGAAA ATCTTCAGAG CTGGATGCTA GTGACTCCAG TTCTAGCAGC 1140

AATCTTTCAC TTGCTAAGGT TAGGCCAAGC AGTGACCTCA ACAACAGTAC TGGCCAGTCT 1200

CCCCACCACA AGGTGCAGAG AAGTGTTTCT TCCAGCCAGA AGCAGAGGCG GTACAGTGAC 1260

CATGCTGGAC CAGCTATTCC TTCAGTTGTG GCATATCCGA AAAGGAGTCA GACCAGCACT 1320

GCAGATAGTG ACCTCAAAGA AGATGGAATT CCTTCTCGGA AATCAAGTGG AAGTGCTGTT 1380

GGAGGAAAGG GAATTGCTCC AGCCAGCCCC ATGCTTGGGA ATGCAAGTAA TCCCAATAAG 1440

GCTGATATTC CTGAACGCAA GAAAAGCTCT ACTGTCCCTA GTACTAATAC AGCATCTGGT 1500

GGAATGACAC GGCGAAATAC TTACGTTTGC AGTGAAAGAA CTACAGCTGA TAGACATTCA 1560

GTAATTCAGA ATGGGAAAGA AAACAGCACT ATTCCTGATC CGAGGACTCC AGTTGCTTCA 1620

ACGCACAGTG TCAGCAGTGC AGCCACCCCA GACCGACTCC GCTTCCCGCG GGGCACTGCC 1680

AGTCGCAGCA CTTTCCATGG CCAGCCCCGG GAGCGGCGGA CTGCCACATA TAATGGCCCG 1740

CCTGCCTCAC CCAGCCTGTC CCATGAAGCC ACACCGTTGT CACAGACTCG AAGCCGAGGC 1800

TCCACTAATC TTTTTAGTAA ATTAACTTCA AAACTTACAA GGAGAAACAT GTCATTCAGG 1860

TTTATCAAAA GGCTTCCAAC TGAATATGAG AGGAACGGGA GATATGAGGG CTCAAGTCGC 1920

AACGTATCTG CTGAGCAAAA GGATGAAAAC AAAGAAGCAA AACCTCGCTC CCTGCGCTTT 1980

ACCTGGAGCA TGAAAACCAC TAGTTCCATG GATCCCAATG ACATGATGCG GGAAATCCGC 2040

AAAGTGCTGG ACGCCAATAA CTGCGACTAT GAGCAGAGAG AGCGCTTCTT ACTCTTCTGT 2100

GTCCATGGTG ATGGGCATGC AGAGAACCTC GTGCAGTGGG AGATGGAGGC AATAAAGGGA 2160

GAAGTCTGCC CTCCTGGCGA CCTGAGGAGG AAGGGAAACA GGAGCCTCCG CGGGCCCATG 2220

TGGAAAGACG CCAGGTCTTG A 2241

Domain Profile

S: 1     ykllktlGegsfgkVklakhketkekvavKiikkkklseeslekikrEieilkklkhpni  60

         y+llkt+G+g+f+kVkla+h +t+++va+Kii+k++l+ +sl+k++rE++i+k+l+hpni

Q: 56    YRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNHPNI  115

         99**********************************************************

S: 61    ikllevietkkklylvleyasggeLfdyieekgrlkekearklfkqlvsavkYlhskgiv  120

         +kl+eviet+k+lyl++eyasgge+fdy++++gr+kekear+ f+q+vsav+Y+h+k+iv

Q: 116   VKLFEVIETDKTLYLIMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKRIV  175

         ************************************************************

S: 121   HrDlKpeNllldkkenikiaDFGlanlfkegklletfcGsppYaaPellkgkkYegpkvD  180

         HrDlK+eNllld+++nikiaDFG++n+f+ g++l+tfcGsppYaaPel++gkkY+gp+vD

Q: 176   HRDLKAENLLLDADMNIKIADFGFSNEFTVGSKLDTFCGSPPYAAPELFQGKKYDGPEVD  235

         ************************************************************

S: 181   vWslGvvLyalvtgklPfdeenlkellekilkgkleipkklskelesLlrklLvvdpekR  240

         vWslGv+Ly+lv+g+lPfd++nlkel+e++l+gk++ip+++s+++e+Ll+++Lv +p kR

Q: 236   VWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPIKR  295

         ************************************************************

S: 241   atieeilkhewl  252

          t+e+i+k++w+

Q: 296   GTLEQIMKDRWI  307

         ***********7

Domain Sequence
(FASTA)

YRLLKTIGKG NFAKVKLARH ILTGREVAIK IIDKTQLNPT SLQKLFREVR IMKILNHPNI 60

VKLFEVIETD KTLYLIMEYA SGGEVFDYLV AHGRMKEKEA RAKFRQIVSA VQYCHQKRIV 120

HRDLKAENLL LDADMNIKIA DFGFSNEFTV GSKLDTFCGS PPYAAPELFQ GKKYDGPEVD 180

VWSLGVILYT LVSGSLPFDG QNLKELRERV LRGKYRIPFY MSTDCENLLK RFLVLNPIKR 240

GTLEQIMKDR WI 252

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR001772	; Kinase-assoc_KA1.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.
IPR015940	; UBA/transl_elong_EF1B_N_euk.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220	; S_TKc; 1.
SM00165	; UBA; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.
PS50030	; UBA; 1.

Prints

Created Date

20-Feb-2013