EPS-CAF-00036

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-CAF-00036

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	187.8	3.7E-55	711	957	247

Status

Unreviewed

Ensembl Protein

ENSCAFP00000029944

UniProt Accession

E2RA12;

Protein Name

Protein Synonyms/Alias

Gene Name

PHLPP2

Gene Synonyms/Alias

PHLPP2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCAFG00000020189	ENSCAFP00000029941	ENSCAFT00000032153
ENSCAFG00000020189	ENSCAFP00000029944	ENSCAFT00000032156

Organism

Canis familiaris

Functional Description

Protein Length

1249

Protein Sequence
(FASTA)

MKRNGSRNCL TRRSRFGSRE RDWLREDVSR GCVYLYGADT TTAATTTSAS ASSDLHLVLC 60

TVETPASEIC AGEGRESLYL QLHGDLVRRL EPTERPLQIV YDYLSRLGFD DPVRIQEEAT 120

DPDLGCMLRF YGEKPCQMDH LDRILLSGIY NVRKGKTQLH KWAERLVVLC GTCLIVSSVK 180

DCQTGKMHIL PLVGGKVEEV KRRQHSLAFS SAGAQAQTYH VSFETLAECQ RWQRQASKVV 240

SQRISTVDLS CYSLEEVPEH LFYSQDITYL NLRHNFMQLE RPGGLDTLYR FSQLKGLNLS 300

HNKLGLFPVL LCEISTLTEL NLSCNGFHDL PSQIGSLLNL QTLCLDGNFL TTLPEELGNL 360

QQLSSLGISF NNFSQIPEVY GKLTMLDKVV MAGNCLKVLN LGVLNRMSHI RHVDLRMNLL 420

KTVVTENLEG NKYITHMDLR DNQLADLDLS SLCSLEQLHC ERNQLRELTL SGFSLRTLYA 480

SSNRLTAVNV YPVPSQLTSL ELSRNLLECV PDWACEAKKM EVLDVSYNLL TEVPMRILSS 540

LSLRKLTVAH NQLQSLPMLV EHIPLEVLDI QHNLLTRLPD TLFSKALNKL NKLEQLEELN 600

LSGNKLKTIP TTIANCKRLH TLVAHSNNIS IFPEILQLPQ IQFVDLSCND LTEILIPEAL 660

PATLQDLDLT GNTNLVLEHK TLDTFSHITT LKIDQKPLPT TDSTVTSTFW SHGLAEMAGQ 720

RNKLCVSALA VDNCAEGVGA VYGMFDGDRN EELPRLLQCT MADVLLEEVQ QSTNDTVFMA 780

NTFLVSHRKL GMAGQKLGSS ALLCYIRPDT ADPASSFSLT VANVGTCQAV LCRSGKPVPL 840

SKVFSLEQDL EEAQRVKDQK AIITEDNKVN GVTCCTRMLG CTYLYPWILP KPHICATPLT 900

IQDELLILGN KALWEHLSYT EAVNAVRHVQ DPLAAAKKLC TLAQSYGCQD NVGAMVVYLN 960

IGEEGCTCEM NGLTLPGPVG FASTTIIKDP PKPTTPSSSS GIASEFGSEM STSEVSSEVG 1020

STASDEHNTV GLDAGLLPRP ERRCSLHPTP TSGVFQRQPS CATFSSNQSD NGLDSDDDQP 1080

VEGVITNGSK VEVEVDIHCC RGRDLENSPT LTENSPTPCP EEHARGSFFG IRRQNSVNSG 1140

ILLPVSKDRM ELQKSPSTSC LYGKKLSNGS IVPLEDSLNL IEVATEAPKK KTGYFAAPTQ 1200

LEPEDQFVVP RDLEEEVKEQ MKQHQESRPE PEPNEEDRTE LPEEFDTAL 1249

Nucleotide Sequence
(FASTA)

ATGAAACGCA ATGGGAGCAG GAATTGTTTG ACTAGGCGAA GTAGGTTTGG TTCTCGAGAA 60

AGAGACTGGC TGAGAGAAGA TGTCAGCAGA GGTTGTGTTT ACCTTTATGG AGCAGACACG 120

ACCACTGCCG CCACAACCAC CTCTGCCTCC GCCTCCTCTG ACTTACATCT TGTCCTGTGC 180

ACCGTGGAGA CACCAGCATC AGAAATCTGT GCTGGTGAGG GAAGGGAAAG TCTTTATTTA 240

CAGCTTCATG GAGACCTAGT CAGGAGACTA GAACCTACAG AACGACCTCT TCAGATCGTT 300

TATGATTACT TGTCCAGGCT GGGATTTGAT GACCCTGTGC GTATACAGGA GGAGGCAACA 360

GATCCTGACC TCGGCTGTAT GCTTCGATTT TATGGTGAAA AACCATGCCA GATGGATCAT 420

CTGGATCGAA TCCTTCTGTC TGGCATCTAT AACGTACGCA AGGGAAAGAC CCAGCTGCAT 480

AAGTGGGCTG AACGCCTAGT TGTTCTCTGT GGCACCTGCC TCATCGTTTC CTCAGTGAAG 540

GATTGTCAGA CTGGAAAGAT GCACATTTTG CCTCTGGTTG GGGGAAAGGT AGAAGAAGTG 600

AAGCGGCGGC AGCATTCCCT CGCATTCAGC TCAGCTGGAG CCCAAGCTCA GACCTATCAT 660

GTCAGCTTTG AGACTCTGGC TGAGTGCCAG AGATGGCAGC GACAGGCATC CAAGGTGGTG 720

TCCCAGCGAA TCAGCACTGT TGACCTCTCA TGTTACAGCC TTGAGGAGGT TCCTGAGCAT 780

CTCTTCTACA GTCAAGATAT CACCTACCTC AATTTGCGAC ACAACTTCAT GCAGTTGGAA 840

AGACCAGGGG GCCTTGACAC TCTGTACAGA TTTTCTCAGC TGAAGGGGCT GAATTTGTCC 900

CACAACAAAC TTGGGTTGTT TCCTGTATTG TTATGTGAGA TTTCTACCCT GACTGAGCTC 960

AACCTCTCCT GTAATGGATT TCACGACCTG CCGAGTCAGA TTGGCAGTCT GCTAAATCTT 1020

CAAACCCTCT GTCTTGATGG CAACTTTCTG ACAACTTTAC CTGAAGAATT GGGAAATCTG 1080

CAACAGCTTT CTTCCCTGGG AATTTCCTTC AACAACTTTA GTCAAATACC TGAAGTTTAT 1140

GGGAAGCTCA CTATGTTAGA TAAAGTGGTT ATGGCAGGAA ATTGCCTGAA AGTCCTAAAC 1200

CTTGGGGTGC TGAACAGGAT GAGCCATATC AGACATGTGG ATTTAAGGAT GAACCTTTTG 1260

AAAACTGTGG TTACTGAAAA TCTGGAGGGA AATAAGTACA TCACCCACAT GGATTTGCGG 1320

GACAATCAAC TAGCTGACTT AGATCTTAGC TCCTTGTGTA GCTTGGAGCA GCTGCACTGT 1380

GAGCGGAACC AGCTGAGAGA GCTGACACTC AGTGGCTTCT CCCTTCGGAC TCTCTACGCC 1440

AGTTCCAACA GGCTGACAGC AGTGAATGTC TATCCAGTAC CCAGTCAACT CACTTCTCTA 1500

GAACTTTCCC GAAATCTGCT AGAATGTGTC CCTGACTGGG CCTGTGAAGC AAAGAAGATG 1560

GAAGTATTAG ATGTGAGCTA TAATCTTCTG ACAGAAGTTC CCATGAGAAT CCTTAGTAGC 1620

TTGAGTCTTA GGAAGCTGAC AGTGGCACAC AACCAGCTGC AGAGCCTGCC CATGCTGGTG 1680

GAGCACATCC CTCTGGAAGT GTTGGATATT CAGCATAACT TACTCACCAG GCTGCCAGAT 1740

ACTCTCTTCT CCAAGGCCTT AAACAAACTA AATAAATTGG AGCAATTGGA GGAACTGAAC 1800

CTAAGTGGCA ACAAGCTTAA AACCATTCCC ACGACCATAG CCAACTGCAA AAGGCTTCAT 1860

ACCCTTGTGG CACACTCCAA CAACATCAGC ATCTTCCCAG AAATACTGCA GTTGCCCCAG 1920

ATCCAGTTTG TAGACCTAAG TTGCAATGAC TTGACAGAAA TCCTGATTCC GGAGGCACTG 1980

CCTGCCACTT TACAAGACCT TGACCTGACT GGAAATACAA ATCTGGTTTT GGAACACAAG 2040

ACATTGGACA CATTTAGCCA TATCACAACC TTGAAAATTG ATCAGAAACC TCTACCAACC 2100

ACTGATTCTA CTGTTACATC AACCTTCTGG AGCCATGGAC TGGCTGAGAT GGCAGGGCAG 2160

AGAAATAAGC TATGTGTATC TGCCCTAGCC GTGGATAACT GTGCAGAGGG GGTAGGAGCT 2220

GTATATGGCA TGTTTGATGG GGACCGAAAC GAGGAGCTCC CTCGCCTCCT CCAGTGTACC 2280

ATGGCAGACG TGCTTTTGGA AGAAGTCCAG CAGTCAACAA ATGACACAGT TTTCATGGCT 2340

AACACCTTCT TGGTATCTCA CAGGAAATTG GGAATGGCTG GCCAGAAGCT GGGCTCCTCT 2400

GCTCTCCTTT GTTATATCCG CCCTGACACT GCCGACCCAG CGAGTAGTTT TAGCTTGACT 2460

GTAGCCAACG TTGGCACATG CCAGGCAGTC CTATGCCGCA GTGGGAAACC AGTGCCACTC 2520

TCAAAAGTCT TCAGCCTAGA ACAGGACCTG GAGGAGGCTC AAAGGGTGAA GGACCAGAAA 2580

GCCATCATAA CAGAGGACAA CAAAGTGAAT GGGGTAACCT GCTGTACCCG GATGCTGGGC 2640

TGTACATACC TCTACCCTTG GATCCTCCCT AAACCTCACA TATGTGCCAC TCCACTTACC 2700

ATTCAAGATG AATTGCTGAT TCTGGGAAAC AAAGCATTGT GGGAACACTT GTCATATACA 2760

GAAGCTGTCA ACGCAGTACG CCATGTGCAA GACCCCTTAG CTGCTGCCAA GAAGCTGTGC 2820

ACATTAGCCC AGAGCTATGG TTGTCAGGAC AATGTGGGGG CGATGGTGGT TTATTTGAAC 2880

ATTGGTGAGG AAGGGTGCAC GTGTGAAATG AATGGGCTCA CCCTCCCAGG TCCTGTGGGC 2940

TTTGCTTCCA CCACCATCAT CAAGGACCCA CCGAAGCCAA CCACTCCTTC CTCTAGTAGT 3000

GGCATTGCCT CTGAGTTCGG CAGCGAGATG TCCACTTCAG AGGTGAGCAG CGAGGTGGGG 3060

TCCACGGCTT CTGATGAACA CAACACTGTC GGGCTGGATG CTGGCTTGCT TCCAAGGCCA 3120

GAGAGGCGCT GTAGCCTCCA TCCAACACCC ACCTCGGGGG TTTTTCAGCG CCAGCCTTCT 3180

TGTGCAACTT TCTCAAGTAA CCAGTCTGAC AATGGCCTGG ACAGTGATGA CGACCAGCCT 3240

GTTGAAGGTG TCATAACAAA TGGCAGCAAA GTAGAAGTAG AAGTAGATAT CCACTGCTGT 3300

AGGGGCAGGG ATCTCGAGAA CTCCCCCACT CTTACAGAGA ATTCTCCAAC CCCATGTCCT 3360

GAGGAACATG CTAGAGGATC ATTTTTTGGG ATCCGAAGAC AGAACAGTGT GAATAGTGGC 3420

ATACTTCTGC CAGTGAGCAA GGACAGGATG GAGTTGCAGA AGTCCCCCTC CACTTCCTGT 3480

CTCTATGGAA AGAAACTCTC AAATGGCTCT ATTGTGCCCC TAGAAGATAG CCTGAACCTC 3540

ATTGAAGTGG CCACAGAAGC ACCCAAGAAG AAAACTGGCT ACTTCGCTGC CCCAACTCAG 3600

CTGGAGCCAG AGGATCAGTT TGTCGTACCT CGTGACCTGG AAGAGGAAGT GAAAGAGCAA 3660

ATGAAACAAC ACCAGGAAAG CAGGCCTGAG CCTGAGCCCA ACGAAGAAGA TCGGACCGAG 3720

CTCCCGGAGG AGTTTGACAC AGCACTG 3747

Domain Profile

S: 2     lvgvvsvngrrnemedavtsspnflkspekkdrlaffgvyDGhggsevakfcseklheil  61

         ++g++++ g+rn+++ ++ +++n ++        a++g++DG++++e  + +++++ ++l

Q: 711   SHGLAEMAGQRNKLCVSALAVDNCAEGV-----GAVYGMFDGDRNEELPRLLQCTMADVL  765

         68999**********8887655555554.....579************************

S: 62    aeelesseseerkvkkalakaFlstdeelkvleeksldidksGstavvalikds......  115

          ee++    ++++ + ++a++Fl  +++l       ++ +k Gs+a++++i+++

Q: 766   LEEVQ----QSTNDTVFMANTFLVSHRKL------GMAGQKLGSSALLCYIRPDtadpas  815

         ***99....77888889************......89***************99999***

S: 116   ..klyvanvGdSravLcrngkavelssdHkpsre.dEleRieeaggsvilkdgaRvlGvL  172

           +l+vanvG ++avLcr+gk+v+ls+ ++ +++ +E +R++++++ +++++  +v+Gv+

Q: 816   sfSLTVANVGTCQAVLCRSGKPVPLSKVFSLEQDlEEAQRVKDQKAIITEDN--KVNGVT  873

         *******************************99989*********9999998..******

S: 173   avsRalGdlylkpyvtpePevtshrltsedefliLasDGlwdvvsneeavslvrdvlekk  232

         +++R+lG++yl+p++ p+P++  ++lt +de liL+ + lw+++s  eav++vr+v +

Q: 874   CCTRMLGCTYLYPWILPKPHICATPLTIQDELLILGNKALWEHLSYTEAVNAVRHVQD--  931

         **********************************************************..

S: 233   eaeqeaakkLvklalargskdnvsaivv  260

           + +aakkL++la+++g++dnv a+vv

Q: 932   --PLAAAKKLCTLAQSYGCQDNVGAMVV  957

         ..************************97

Domain Sequence
(FASTA)

SHGLAEMAGQ RNKLCVSALA VDNCAEGVGA VYGMFDGDRN EELPRLLQCT MADVLLEEVQ 60

QSTNDTVFMA NTFLVSHRKL GMAGQKLGSS ALLCYIRPDT ADPASSFSLT VANVGTCQAV 120

LCRSGKPVPL SKVFSLEQDL EEAQRVKDQK AIITEDNKVN GVTCCTRMLG CTYLYPWILP 180

KPHICATPLT IQDELLILGN KALWEHLSYT EAVNAVRHVQ DPLAAAKKLC TLAQSYGCQD 240

NVGAMVV 247

Keyword

Complete proteome; Leucine-rich repeat; Reference proteome; Repeat.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Cavia porcellus"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>